JP3628242B2

JP3628242B2 - Recessed part eye drop container

Info

Publication number: JP3628242B2
Application number: JP2000243922A
Authority: JP
Inventors: 洋一河嶋; 幸男樟; 博山田
Original assignee: Santen Pharmaceutical Co Ltd
Current assignee: Santen Pharmaceutical Co Ltd
Priority date: 1999-08-17
Filing date: 2000-08-11
Publication date: 2005-03-09
Anticipated expiration: 2020-08-11
Also published as: JP2001120638A

Description

【０００１】
【発明の属する技術分野】
本発明は、薬液を充填する容器本体のうち、少なくとも胴部が可撓性のある中空円筒状に構成されている点眼容器に関する。
【０００２】
【従来の技術】
従来の点眼容器、特に医療用点眼液に使用される点眼容器としては、中空円筒状のものが汎用されている。例えば、中空円筒状に形成された容器本体に中栓を装着した容器、ブロー成形や真空成形等により容器本体の胴部及び注液口部を共に中空円筒状に一体形成した容器（例えば、実公昭３９−１１９９１号公報参照）が用いられている。また、その容器素材としては、成形の容易さ等から軟質の熱可塑性樹脂が用いられている。
【０００３】
【発明が解決しようとする課題】
この種の点眼容器では、容器本体内の薬液を投与する場合、容器本体の胴部を二本の指先で把持して、容器本体の注液口が投与対象の眼に対面する投与姿勢に保持し、この姿勢を維持しつつ容器本体の胴部を容器軸線側に押圧操作することにより、容器本体の注液口から薬液を滴下供給する。
【０００４】
この押圧操作が容易にできるよう、中空円筒状に形成された点眼容器は軟質の熱可塑性樹脂で成形されているが、押圧力の弱い高齢者等においては押圧操作の制御に不自由を感じることがある。また、把持力が弱い高齢者等においては押圧操作を行う際、指先の把持位置が安定しづらい場合もある。
【０００５】
本発明は、上述の実状に鑑みて為されたものであって、その主たる課題は、容器本体の胴部に対する簡単かつ安価な改造をもって、持ち易く、且つスクイズ性に優れた使い勝手の良い点眼容器を提供する点にある。
【０００６】
【課題を解決するための手段】
本発明の窪み部形成点眼容器の特徴構成は、可撓性のある中空円筒状の胴部に、二本の指先で把持可能な窪み部が形成されており、前記窪み部は、容器軸線方向視においては前記胴部の他の部位の曲率よりも小さな曲率で緩やかに彎曲形成されている挟持面から構成してあると共に、押圧操作力が１．７８〜３．３４Ｎである点にある。
上記特徴構成によれば、容器内の薬液を投与する際、容器の胴部に形成された窪み部を、二本の指先で把持するから、指先の把持位置が安定する。しかも、容器の胴部を押圧操作するとき、その指先に接触している胴部の一部が既に緩やかに窪み形成されているから、円筒状の胴部の一部を弾性復元力に抗して窪み変形させる場合に比して、その押圧操作力を軽減することができる。
従って、中空円筒状の胴部に窪み部を形成するだけの簡単かつ安価な改造でありながら、従来の点眼容器に比して持ち易く、しかも、押圧操作力の軽減化によってスクイズ性を改善することができるから、容器内の薬液を正確、容易に投与することのできる使い勝手の良い窪み部形成点眼容器を提供することができた。
さらに、押圧操作力が１．７８〜３．３４Ｎであるため、窪み部を設けていない点眼容器に対する押圧操作力の約１／３から約半分の押圧操作力で内容物（水）を滴下でき、スクイズ性が向上する。このようにスクイズ性を向上させることによって、押圧力や把持力が弱い人であっても、緩やかに彎曲形成されている挟持面を容易に操作して、容器内に収容された薬液を滴下させることができる。
前記窪み部形成点眼容器は、例えば、２．０〜２．４ｇのポリエチレンでブロー成形又は真空成形し、記窪み部形成点眼容器の胴部の高さが３３．７ｍｍ、直径が１９．６ｍｍであり、前記窪み部の形状は、高さが１９．５ｍｍ、幅が１３．３ｍｍの楕円形である。
【０００７】
本発明の窪み部形成点眼容器の特徴構成は、前記窪み部が、胴部の円周方向二箇所の各々に窪み形成された偏平又はほぼ偏平な把持面から構成されている点にある。
上記特徴構成によれば、容器の胴部を二本の指先で把持する際、胴部の二箇所に形成された偏平又はほぼ偏平な把持面を把持することになるから、把持した指先の局部的な圧迫感が少なくなり、持ち易さをより改善することができる。
【０００８】
本発明の窪み部形成点眼容器の特徴構成は、前記窪み部が、胴部の円周方向二箇所の各々に容器軸線方向中央側ほど容器軸線側に近づく状態で窪み形成された湾曲凹状の把持面から構成されている点にある。
上記特徴構成によれば、容器の胴部を二本の指先で把持する際、胴部の二箇所に形成された指先の曲面に近い湾曲凹状の把持面を把持することになるから、把持した指先の局部的な圧迫感がない又は殆どなく、持ち易さを一層改善することができる。
【０００９】
本発明の窪み部形成点眼容器の特徴構成は、前記胴部を備えた容器本体が、成形と同時に液体が充填される熱可塑性材料製の容器本体から構成されている点にある。
上記特徴構成によれば、特に、製造コストの低廉化が要求される医療用点眼容器に対しても、製造コストの低廉化を図りつつ、持ち易さとスクイズ性を改善することができる。
【００１０】
【発明の実施の形態】
〔第１実施形態〕
図１〜図５は、主として医療用に用いられる本発明の窪み部形成点眼容器を示し、ブロー成形又は真空成形と同時に所定量の薬液が充填された可撓性のある熱可塑性材料製の容器本体Ａと、該容器本体Ａのネジ筒部５に形成された雄ネジ５ａに着脱自在に螺合されるキャップＢとから構成されている。
前記容器本体Ａは、内側に彎曲する円形状の底部１と、これの周縁に連なる中空円筒状の胴部２と、該胴部２の肩部分２ａに連続する円筒状の首部３と、該首部３の上側位置から直径方向外方に膨出する円環状段部４と、これの上側に連続する雄ネジ５ａを備えたネジ筒部５と、これの上側に連続する注液口６ａを備えた注液筒部６とから構成されている。
【００１１】
この容器本体Ａの構成材料である熱可塑性材料としては、ポリエチレン、ポリエチレンーポリプロピレン、ポリプロピレン、ポリエチエチレンテレフタレート、ポリカーボネート等があり、成形された容器本体Ａ全体が弾性変形可能に構成されている。
【００１２】
前記容器本体Ａの注液筒部６には、注液口６ａ側ほど内径が大となる有底円錐状の凹部６ｂが窪み形成され、この凹部６ｂの底面には、前記胴部２の指による押圧操作に連れて容器本体Ａから押出される液滴量を設定量に制御可能な小径の注液孔６ｃが形成されている。
前記凹部６ｂの深さは２〜７ｍｍの範囲、好ましくは、５〜７ｍｍの範囲、最も好ましくは６ｍｍに構成するとともに、前記注液口６ａの口径（口元径）は、薬液の液性に合わせてφ２．０ｍｍ〜φ４．０ｍｍの範囲で調整する。
１滴量を一定化（目的に合わせて１滴量当たり２５〜５０μＬの範囲内に調整）するため、表面張力が大きい液性の場合は、前記注液口６ａの口径を小さくし、表面張力が小さい液性の場合は、前記注液口６ａの口径を大きくする。
更に、前記注液孔６ｃは、φ０．１ｍｍ〜φ０．８ｍｍの範囲の径の針を用いて形成する。この針の径は、小さい方が好ましく、φ０．２ｍｍ程度が最も好ましいが、あまり小さいと技術的に困難となるので、実際には、φ０．４ｍｍ〜φ０．６ｍｍの範囲の針を用いる。
【００１３】
前記容器本体Ａの胴部２には、二本の指先で把持可能な窪み部７が形成されており、更に、この窪み部７は、胴部２の円周方向二箇所で、かつ、容器軸線Ｘを挟んで相対向する部位の各々に窪み形成された偏平又はほぼ偏平な一対の挟持面７ａから構成されている。
前記各挟持面７ａは、容器軸線Ｘ方向視においては胴部２の他の部位の曲率よりも小さな曲率で緩やかに彎曲形成されているとともに、容器軸線Ｘ方向と直行する径方向視（正面視）では、その容器軸線Ｘ方向の両端部分を除く中間部分が容器軸線Ｘと平行な直線状に構成されている。
【００１４】
前記キャップＢには、容器本体Ａの雄ネジ５ａに螺合したとき、該容器本体Ａの凹部６ｂに内嵌して密封する栓状突起８が一体形成されている。
【００１５】
〔第２実施形態〕
図６〜図１０は、前記容器本体Ａの胴部２に形成された二本の指先で把持可能な窪み部７の別実施形態を示し、これは、胴部の円周方向二箇所の各々に容器軸線Ｘ方向中央側ほど容器軸線Ｘ側に近づく状態で窪み形成された一対の湾曲凹状の把持面７ｂから構成されている。
前記各挟持面７ｂは、容器軸線Ｘ方向視においては胴部２の他の部位の曲率よりも小さな曲率で緩やかに彎曲形成されているとともに、容器軸線Ｘ方向と直行する径方向視（正面視）では、指先の彎曲にほぼ沿うように、容器軸線Ｘ方向中央側ほど容器軸線Ｘ側に近づく状態で彎曲形成されている。
尚、その他の構成は、第１実施形態で説明した構成と同一であるから、同一の構成箇所には、第１実施形態と同一の番号を付記してそれの説明は省略する。
【００１６】
〔第３実施形態〕
上述の各実施形態では、ブロー成形又は真空成形された容器本体Ａの注液筒部６に、注液口６ａ側ほど内径が大となる有底円錐状の凹部６ｂと、胴部２の指先による押圧操作に連れて容器本体Ａから押出される液滴量を設定量に制御可能な小径の注液孔６ｃとを予め形成してある点眼容器について説明したが、本願発明は、このような点眼容器に限定される者ではなく、図１１に示すように、ブロー成形又は真空成形と同時に所定量の薬液が充填・密封された可撓性のある熱可塑性材料製の容器本体Ａの雄ネジ５ａに、容器本体Ａの先端部に注液孔を貫通形成するための針状突起９を一体形成してあるキャップＢを脱着自在に螺合して、該キャップＢの通常の閉止位置よりも一段深い締込み側への螺合操作により、キャップＢの針状突起９で容器本体Ａの先端部に注液孔６ａを形成するように構成してある点眼容器であってもよい。
尚、その他の構成は、第１実施形態で説明した構成と同一であるから、同一の構成箇所には、第１実施形態と同一の番号を付記してそれの説明は省略する。
【００１７】
〔第４実施形態〕
上述の第１、第２実施形態では、前記容器本体Ａとして、ブロー成形又は真空成形によって中栓機能を備えた状態で成形された点眼容器を例示したが、このような構成の点眼容器に限定されるものではなく、図１２に示すように、容器本体Ａの筒状口部１０に、射出成形された中栓部材１１を嵌合して構成される点眼容器であってもよい。
尚、その他の構成は、第１実施形態で説明した構成と同一であるから、同一の構成箇所には、第１実施形態と同一の番号を付記してそれの説明は省略する。
【００１８】
【実施例】
本発明に係る胴部に窪み部を形成した２種の点眼容器と、比較例に係る胴部に窪み部を形成していない中空円筒状の点眼容器とを作成し、これらの点眼容器の操作性を、スクイズ性を指標として検討した。
実施例１に係るポリエチレン製点眼容器は、第１実施形態の容器本体Ａに対応する形状を有しているものである。詳しくは、前記実施例１に係るポリエチレン製点眼容器は、その容器軸線Ｘ方向の全長が５６．４ｍｍであって、前記注液口６ａの口径（口元径）を２．９ｍｍに形成してある。そして、前記胴部２は、高さが３３．７ｍｍ、直径１９．６ｍｍの上下端が面取りされた円筒状に形成されている。さらに前記胴部２の側面には、一対の前記窪み部７が、高さＨが１９．５ｍｍ、幅Ｗが１３．３ｍｍに窪み形成され、その深さＤは最深部で１．６ｍｍに設定されている（図１、２参照）。
実施例２に係るポリエチレン製点眼容器は、第２実施形態の容器本体Ｂに対応する形状を有しているものである。詳しくは、実施例２に係るポリエチレン製点眼容器は、その容器軸線Ｘ方向の全長が５６．４ｍｍであって、前記注液口６ａの口径（口元径）を２．９ｍｍに形成してある。そして、前記胴部２は、高さが３３．７ｍｍ、直径１９．６ｍｍの上下端が面取りされた円筒状に形成してある。そして、前記胴部２の側面には、一対の前記窪み部７が高さＨが１９．５ｍｍ、幅Ｗが１３．３ｍｍに窪み形成され、その深さＤは最深部で１．６ｍｍに設定されている（図６、７参照）。
【００１９】
比較例に係る従来のポリエチレン製点眼容器は、図１３に示すように、中空円筒状の胴部を有していて、窪み部を設けていない点を除けば、前記実施例１、２と同じ構成である。従って、同一の構成箇所には、第１実施形態と同一の番号を付記してそれの説明は省略する。
【００２０】
これら３タイプのポリエチレン製点眼容器のそれぞれは、東ソー１７５Ｋ（商品名、東ソー株式会社製）を原料とするものであって、これを溶融し、１容器あたり重量が２．０、２．２及び２．４ｇになるように成形して得た。
【００２１】
水を収容したポリエチレン製点眼容器（検体）を、前記注液筒部６を下向きにして、測定装置の所定位置にセットした。そして、このポリエチレン製点眼容器の窪み部７（比較例にあっては、胴部）の外側面中央部分に前記スクイズ性測定器のチップを当て、前記注液筒部６の凹部６ｂを除く内部に水が充満していないこと（前記注液口６ａ付近に空気が滞留していないこと）を確認してから、前記チップを前記ポリエチレン製点眼容器の軸線側に移動させて押圧し、前記ポリエチレン製点眼容器の注液口６ａから１滴の水が滴下するのに要する押圧操作力を、前記測定装置に付属のデジタルフォースゲージで測定した。
前述した９種のポリエチレン製点眼容器のスクイズ性試験において、それぞれの種に対して５本の検体を用いて、１本の検体につき５回試験を行なった。これらの結果の平均値を表１に示す。
【００２２】
【表１】

【００２３】
表１に示すように、前記点眼容器の容器重量が増加するほど、即ち、その壁厚が厚くなるほど、これらに収容した水を１滴滴下するために必要な押圧操作力が大きくなることは、実施例１、２並びに比較例のすべてにおいて共通していることがわかる。
【００２４】
しかし、同じ容器重量で比較すると、前記窪み部７を、前記胴部７に形成してある実施例１、２に係る点眼容器は、比較例に係る点眼容器に対する押圧操作力の約１／３から約半分の押圧操作力で内容物（水）を滴下することができ、容器本体の胴部に対して簡単かつ安価な改造を施すことによって、スクイズ性が向上していることがわかる。このようにしてスクイズ性を向上させることによって、押圧力や把持力が弱い人であっても、容易にを操作して、容器内に収容された薬液を滴下させることができる点眼容器を得ることができた。
【００２５】
〔その他の実施形態〕
（１）上述の各実施形態では、前記窪み部７を構成する各挟持面７ａ，７ｂを、容器軸線Ｘ方向視において胴部２の他の部位の曲率よりも小さな曲率で緩やかに彎曲形成したが、各挟持面７ａ，７ｂを、容器軸線Ｘ方向視において接線方向に沿う一直線状の偏平面、又は、容器軸線Ｘ側に向かって窪む凹状湾曲に形成して実施してもよい。
（２）前記容器本体Ａとしては、少なくとも胴部２が可撓性のある中空円筒状に構成されているものであれば、如何なる構造の容器本体Ａを用いて実施してもよい。
（３）上述の各実施形態では、前記窪み部７を構成する各挟持面７ａ，７ｂを、胴部２の円周方向二箇所に形成したが、胴部２の円周方向三箇所以上に形成して実施してもよい。
【図面の簡単な説明】
【図１】本発明の窪み部形成点眼容器の第１実施形態を示す容器本体の正面図
【図２】容器本体の側面図
【図３】点眼容器全体の断面側面図
【図４】容器本体の断面平面図
【図５】滴下投与時の容器本体の断面側面図
【図６】本発明の窪み部形成点眼容器の第２実施形態を示す容器本体の正面図
【図７】容器本体の側面図
【図８】点眼容器全体の断面側面図
【図９】容器本体の断面平面図
【図１０】滴下投与時の容器本体の断面側面図
【図１１】本発明の窪み部形成点眼容器の第３実施形態を示す全体の断面正面図
【図１２】本発明の窪み部形成点眼容器の第４実施形態を示す全体の断面正面図
【図１３】比較例に係る容器本体の側面図
【符号の説明】
Ａ容器本体
Ｘ容器軸線
２胴部
７窪み部
７ａ挟持面
７ｂ挟持面[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an ophthalmic container in which at least a body part is configured in a flexible hollow cylindrical shape among container bodies filled with a chemical solution.
[0002]
[Prior art]
A hollow cylindrical container is widely used as a conventional eye drop container, particularly an eye drop container used for a medical eye drop. For example, a container in which a hollow plug is attached to a container body formed into a hollow cylinder, or a container (for example, an actual container) in which a body part and a liquid injection port part of the container body are integrally formed in a hollow cylinder by blow molding or vacuum forming. No. 39-11991) is used. As the container material, a soft thermoplastic resin is used for ease of molding and the like.
[0003]
[Problems to be solved by the invention]
In this type of ophthalmic container, when the drug solution in the container body is administered, the body part of the container body is held with two fingertips, and the liquid injection port of the container body is held in an administration posture facing the eye to be administered. Then, the chemical liquid is dropped and supplied from the liquid injection port of the container body by pressing the body part of the container body toward the container axis while maintaining this posture.
[0004]
In order to facilitate this pressing operation, the ophthalmic container formed in a hollow cylindrical shape is formed of a soft thermoplastic resin, but the elderly with weak pressing force feel inconvenience in controlling the pressing operation. There is. In addition, in elderly people with weak gripping force, the gripping position of the fingertip may be difficult to stabilize when performing a pressing operation.
[0005]
The present invention has been made in view of the above-described actual situation, and its main problem is an easy-to-use ophthalmic container that is easy to hold and has excellent squeeze characteristics with a simple and inexpensive modification to the body of the container body. Is to provide
[0006]
[Means for Solving the Problems]
According to the present invention, the hollow portion-forming eye drop container has a hollow portion having a flexible hollow cylindrical shape, and a hollow portion that can be gripped by two fingertips is formed. In view, it is composed of a clamping surface that is gently bent with a curvature smaller than the curvature of the other part of the body, and the pressing operation force is 1.78 to 3.34 N.
According to the above characteristic configuration, when the drug solution in the container is administered, the depression formed in the body of the container is gripped by the two fingertips, so that the gripping position of the fingertip is stabilized. Moreover, when pressing the barrel part of the container, a part of the barrel part that is in contact with the fingertip has already been gently depressed, so that a part of the cylindrical barrel part resists the elastic restoring force. Therefore, the pressing force can be reduced as compared with the case where the depression is deformed.
Therefore, it is a simple and inexpensive modification that simply forms a hollow in the hollow cylindrical body, but is easier to hold than conventional eye drop containers, and also improves squeeze by reducing the pressing force. Therefore, it was possible to provide an easy-to-use depression-forming ophthalmic container that can accurately and easily administer the drug solution in the container.
Furthermore, since the pressing operation force is 1.78 to 3.34 N, the content (water) can be dripped with a pressing operation force of about 1/3 to about half of the pressing operation force with respect to the ophthalmic container not provided with the depression. , Squeeze property is improved. By improving the squeezing property in this way, even a person with weak pressing force or gripping force can easily operate the sandwiching surface that is gently bent to drop the chemical solution stored in the container. be able to.
The hollow portion-forming eye drop container is, for example, blow-molded or vacuum-molded with 2.0 to 2.4 g of polyethylene, and the body portion of the hollow portion-formed eye drop container has a height of 33.7 mm and a diameter of 19.6 mm. In addition, the shape of the recess is an ellipse having a height of 19.5 mm and a width of 13.3 mm.
[0007]
A characteristic configuration of the ophthalmic container for forming a dent portion according to the present invention is that the dent portion is constituted by a flat or substantially flat gripping surface formed by dents in two circumferential directions of the body portion.
According to the above characteristic configuration, when gripping the body of the container with two fingertips, a flat or almost flat gripping surface formed at two locations of the body is gripped. The feeling of oppressiveness is reduced, and the ease of holding can be improved.
[0008]
According to the present invention, the depression-forming ophthalmic container has a curved concave shape in which the depression is formed in a state where the depression is closer to the container axis side toward the center side in the container axis direction at each of the two circumferential directions of the body part. The point is that it is composed of surfaces.
According to the above characteristic configuration, when gripping the body of the container with two fingertips, the gripping surface having a curved concave shape close to the curved surface of the fingertip formed at two locations of the body is gripped. Ease of holding can be further improved with little or no local fingertip pressure.
[0009]
A characteristic configuration of the eye drop container for forming a recess according to the present invention is that a container body provided with the body is formed of a container body made of a thermoplastic material that is filled with a liquid simultaneously with molding.
According to the above-described characteristic configuration, it is possible to improve the ease of holding and squeeze while reducing the manufacturing cost, particularly for medical eye drop containers that are required to reduce the manufacturing cost.
[0010]
DETAILED DESCRIPTION OF THE INVENTION
[First Embodiment]
1 to 5 show a hollow portion-forming eye drop container of the present invention mainly used for medical purposes, and a container made of a flexible thermoplastic material filled with a predetermined amount of chemical solution simultaneously with blow molding or vacuum molding. The main body A includes a cap B that is detachably screwed into a male screw 5a formed in the screw cylinder portion 5 of the container main body A.
The container body A includes a circular bottom 1 bent inward, a hollow cylindrical body 2 continuous to the periphery of the container body A, a cylindrical neck 3 continuous to the shoulder 2a of the body 2, An annular stepped portion 4 bulging outward from the upper side of the neck portion 3 in the diametrical direction, a screw cylinder portion 5 having a male screw 5a continuous on the upper side thereof, and a liquid injection port 6a continuous on the upper side thereof. The liquid injection cylinder part 6 is provided.
[0011]
Examples of the thermoplastic material that is a constituent material of the container body A include polyethylene, polyethylene-polypropylene, polypropylene, polyethylene terephthalate, and polycarbonate, and the entire molded container body A is configured to be elastically deformable.
[0012]
The liquid injection cylinder portion 6 of the container main body A is formed with a bottomed conical concave portion 6b whose inner diameter increases toward the liquid injection port 6a, and a finger of the barrel portion 2 is formed on the bottom surface of the concave portion 6b. A small-diameter liquid injection hole 6c is formed that can control the amount of droplets extruded from the container main body A to a set amount in accordance with the pressing operation.
The depth of the recess 6b is in the range of 2 to 7 mm, preferably in the range of 5 to 7 mm, and most preferably 6 mm, and the diameter (mouth diameter) of the liquid injection port 6a is adjusted to the liquidity of the chemical solution. And adjust in the range of φ2.0 mm to φ4.0 mm.
In order to make the amount of one drop constant (adjusted within the range of 25 to 50 μL per drop according to the purpose), in the case of a liquid with a large surface tension, the diameter of the liquid injection port 6a is reduced to obtain a surface tension. Is small, the diameter of the liquid injection port 6a is increased.
Further, the liquid injection hole 6c is formed using a needle having a diameter in the range of φ0.1 mm to φ0.8 mm. The diameter of the needle is preferably small, and is most preferably about φ0.2 mm. However, if it is too small, it becomes technically difficult, so in practice, a needle in the range of φ0.4 mm to φ0.6 mm is used.
[0013]
The body 2 of the container body A is formed with a recess 7 that can be gripped by two fingertips. Further, the recess 7 is provided at two locations in the circumferential direction of the body 2 and the container It is composed of a pair of flat or substantially flat sandwiching surfaces 7a that are recessed in each of the opposing portions across the axis X.
Each of the clamping surfaces 7a is gently curved with a curvature smaller than the curvature of the other part of the body 2 when viewed in the container axis X direction, and is viewed in the radial direction (front view) perpendicular to the container axis X direction. ), An intermediate portion excluding both end portions in the container axis X direction is configured in a straight line parallel to the container axis X.
[0014]
The cap B is integrally formed with a plug-like protrusion 8 that is fitted into the recess 6b of the container main body A and sealed when screwed into the male screw 5a of the container main body A.
[0015]
[Second Embodiment]
FIGS. 6-10 shows another embodiment of the hollow part 7 which can be hold | gripped with the two fingertips formed in the trunk | drum 2 of the said container main body A, and this is each two circumferential directions of a trunk | drum. It is comprised from a pair of holding | grip surface 7b of a curved concave shape in which the hollow was formed so that the container axial line X direction center side might approach the container axial line X side.
Each of the clamping surfaces 7b is gently curved with a curvature smaller than the curvature of the other part of the body 2 when viewed in the container axis X direction, and is viewed in the radial direction (front view) perpendicular to the container axis X direction. ), The curve is formed so as to be closer to the container axis X side toward the center in the container axis X direction so as to substantially follow the curve of the fingertip.
In addition, since the other structure is the same as the structure demonstrated in 1st Embodiment, the same number is attached to the same structure location as 1st Embodiment, and the description is abbreviate | omitted.
[0016]
[Third Embodiment]
In each of the above-described embodiments, the injection cylinder 6 of the container body A that has been blow-molded or vacuum-formed, the bottomed conical recess 6b having an inner diameter that increases toward the injection port 6a, and the fingertip of the body 2 Although the ophthalmic container in which the small-diameter liquid injection hole 6c capable of controlling the amount of liquid droplets extruded from the container main body A to the set amount in accordance with the pressing operation according to the above has been described, As shown in FIG. 11, the male thread of the container body A made of a flexible thermoplastic material that is filled and sealed with a predetermined amount of a chemical solution simultaneously with blow molding or vacuum molding, as shown in FIG. A cap B in which a needle-like projection 9 for integrally forming a liquid injection hole is formed at the front end of the container main body A is detachably screwed to 5a, so that the cap B can be removed from a normal closing position. By the screwing operation to the deeper tightening side, the needle-shaped protrusion 9 of the cap B The distal end portion of the vessel main body A may be an eye drop container is arranged to form a injection hole 6a.
In addition, since the other structure is the same as the structure demonstrated in 1st Embodiment, the same number is attached to the same structure location as 1st Embodiment, and the description is abbreviate | omitted.
[0017]
[Fourth Embodiment]
In the first and second embodiments described above, as the container main body A, an ophthalmic container formed with a plug function by blow molding or vacuum molding is illustrated, but the container main body A is limited to an ophthalmic container having such a configuration. Instead, as shown in FIG. 12, an ophthalmic container configured by fitting an injection-molded inner plug member 11 into the cylindrical mouth portion 10 of the container main body A may be used.
In addition, since the other structure is the same as the structure demonstrated in 1st Embodiment, the same number is attached to the same structure location as 1st Embodiment, and the description is abbreviate | omitted.
[0018]
【Example】
Two types of eye drop containers in which a hollow part according to the present invention is formed, and hollow cylindrical eye drop containers in which a hollow part is not formed in a body part according to a comparative example are created, and the operation of these eye drop containers The squeeze property was used as an index.
The polyethylene eye drop container according to Example 1 has a shape corresponding to the container main body A of the first embodiment. Specifically, the polyethylene eye drop container according to Example 1 has a total length in the container axis X direction of 56.4 mm, and the diameter (mouth diameter) of the liquid injection port 6a is 2.9 mm. . The body 2 is formed in a cylindrical shape having a height of 33.7 mm and a diameter of 19.6 mm chamfered. Furthermore, a pair of said recessed parts 7 are formed in the side surface of the said trunk | drum 2 so that height H may be 19.5 mm and width W may be 13.3 mm, and the depth D is set to 1.6 mm in the deepest part. (See FIGS. 1 and 2).
The polyethylene eye drop container according to Example 2 has a shape corresponding to the container main body B of the second embodiment. Specifically, the polyethylene eye drop container according to Example 2 has a total length of 56.4 mm in the container axis X direction, and the diameter (mouth diameter) of the liquid injection port 6a is 2.9 mm. The body 2 is formed in a cylindrical shape having a height of 33.7 mm and a diameter of 19.6 mm chamfered. A pair of the recessed portions 7 is formed in the side surface of the body portion 2 to have a height H of 19.5 mm and a width W of 13.3 mm, and the depth D is set to 1.6 mm at the deepest portion. (See FIGS. 6 and 7).
[0019]
As shown in FIG. 13, the conventional polyethylene eye drop container according to the comparative example is the same as the first and second embodiments except that it has a hollow cylindrical body and is not provided with a recess. It is a configuration. Accordingly, the same components are denoted by the same reference numerals as in the first embodiment, and description thereof is omitted.
[0020]
Each of these three types of polyethylene eye drop containers is made from Tosoh 175K (trade name, manufactured by Tosoh Corporation), and is melted to have a weight of 2.0, 2.2 and It was obtained by molding to 2.4 g.
[0021]
A polyethylene eye drop container (specimen) containing water was set at a predetermined position of the measuring apparatus with the liquid injection cylinder portion 6 facing downward. And the chip | tip of the said squeeze property measuring device is applied to the center part of the outer surface of the hollow part 7 (the trunk part in the comparative example) of this polyethylene eye drop container, and the interior excluding the recess 6b of the liquid injection cylinder part 6 After confirming that the water is not filled with water (no air stays in the vicinity of the liquid injection port 6a), the tip is moved to the axis side of the polyethylene eye drop container and pressed, and the polyethylene The pressing force required to drop one drop of water from the injection port 6a of the eye drop container was measured with a digital force gauge attached to the measuring device.
In the squeeze property test of the nine types of polyethylene eye drop containers described above, the test was performed five times for each sample using five samples for each species. The average value of these results is shown in Table 1.
[0022]
[Table 1]

[0023]
As shown in Table 1, as the container weight of the eye drop container increases, that is, as the wall thickness increases, the pressing operation force necessary for dropping one drop of water contained in these drops increases. It turns out that it is common in all of Examples 1, 2 and the comparative example.
[0024]
However, when compared with the same container weight, the ophthalmic container according to Examples 1 and 2 in which the hollow part 7 is formed in the body part 7 is approximately 1/3 of the pressing operation force with respect to the ophthalmic container according to the comparative example. It can be seen that the contents (water) can be dropped with about half the pressing operation force, and that the squeeze property is improved by making a simple and inexpensive modification to the body of the container body. By improving the squeeze property in this way, even if a person with weak pressing force or gripping force is operated, it is possible to obtain an eye drop container that can be easily operated to drop the chemical contained in the container. I was able to.
[0025]
[Other Embodiments]
(1) In each of the above-described embodiments, the sandwiching surfaces 7a and 7b constituting the hollow portion 7 are gently bent with a curvature smaller than the curvature of other portions of the body portion 2 when viewed in the container axis X direction. However, the sandwiching surfaces 7a and 7b may be formed by forming a straight flat surface along the tangential direction when viewed from the container axis X direction or a concave curve that is recessed toward the container axis X side.
(2) As said container main body A, as long as the trunk | drum 2 is comprised by the flexible hollow cylinder shape, you may implement using the container main body A of what kind of structure.
(3) In each above-mentioned embodiment, although each clamping

surface

7a, 7b which comprises the said hollow part 7 was formed in two places of the circumferential direction of the trunk | drum 2, it is more than three places of the circumferential direction of the trunk | drum 2. You may form and implement.
[Brief description of the drawings]
FIG. 1 is a front view of a container main body showing a first embodiment of a depression-forming eye drop container of the present invention. FIG. 2 is a side view of the container main body. FIG. 5 is a cross-sectional side view of the container main body at the time of dripping administration. FIG. 6 is a front view of the container main body showing a second embodiment of the indentation-forming eye drop container of the present invention. FIG. 8 is a cross-sectional side view of the entire eye drop container. FIG. 9 is a cross-sectional plan view of the container main body. FIG. 10 is a cross-sectional side view of the container main body during dripping administration. FIG. 12 is an overall cross-sectional front view showing a fourth embodiment of the eye drop-forming eye drop container of the present invention. FIG. 13 is a side view of a container main body according to a comparative example. Description】
A Container body X Container axis 2 Body part 7 Recessed part 7a Clamping surface 7b Clamping surface

Claims

A hollow portion having a hollow hollow cylindrical shape is formed with a hollow portion that can be gripped by two fingertips. The hollow portion is in accordance with the curvature of other portions of the body portion in the container axial direction. And a depression forming eye drop container having a pressing operation force of 1.78 to 3.34N.

2. The depression-forming eyedrop container according to claim 1, wherein the depression-forming eyedrop container is blow-molded or vacuum-molded with 2.0 to 2.4 g of polyethylene.

The hollow part forming eye drop container according to claim 1, wherein the body part of the hollow part forming eye drop container has a height of 33.7 mm and a diameter of 19.6 mm.

The shape of the said hollow part is an oval container of a hollow part formation of Claim 1 whose height is 19.5 mm and whose width | variety is 13.3 mm.

The indentation container for forming indentations according to claim 1, wherein the indentation is composed of a flat or substantially flat gripping surface that is indented in each of two circumferential directions of the body.

The hollow part according to claim 5 , wherein the hollow part is configured by a curved concave gripping surface formed in a state in which the hollow part is closer to the container axis side toward the container axis direction center side in each of two circumferential directions of the body part. Forming eye drop container.

The hollow part formation eye drop container as described in any one of Claims 1-6 comprised from the container main body made from a thermoplastic material with which the container main body provided with the said trunk | drum is filled with a chemical | medical solution simultaneously with shaping | molding.