JP2003339822A - High temperature sterilized eye drop applicator - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an eye drop applicator, enabling easy manufacture and easy sterilization, securing sterilization assurance and having excellent eye drops applying operability. <P>SOLUTION: This applicator is integrally formed of resin material not molten and deformed when sterilization is performed continuously for twenty minutes under the condition of 121°C. <P>COPYRIGHT: (C)2004,JPO

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical eyedrop container (hereinafter simply referred to as an eyedropper container) and an eyedropper that accommodate a medical eyedrop solution freely.

[0002]

2. Description of the Related Art As an eye drop container filled with a medical eye drop solution, there is, for example, the one shown in FIG. 6 or 7. That is, when the inner plug 11 is attached to the container body 10 formed in a hollow cylindrical shape, and the cap is included, the total amount of the eyedropper becomes 3
A so-called three-piece type eye drop container (FIG. 6) formed from a member, an integrally molded type container (FIG. 7) in which a liquid injection cylinder and a container body are integrally formed by a blow molding technique, a so-called bottle pack eye drop The container is commonly used. In this bottle pack ophthalmic container, a predetermined amount of drug solution is filled and sealed simultaneously with blow molding or vacuum forming. In particular, in the container shown in FIG. 7, a needle-like projection 9 for penetrating and forming a liquid injection hole is integrally formed at the tip of the container body A on the male screw 5a of the container body A made of a flexible thermoplastic material. This is a structure in which the cap B is detachably screwed. In this container, the needle-like projection 9 of the cap B forms a liquid injection hole 6c in the liquid injection portion at the tip of the container body A by screwing operation to the tightening side that is one step deeper than the normal closed position of the cap B. To do. Further, as another eyedrop container, for example, Japanese Patent Laid-Open No. 2001-1206
As shown in FIG. 39, a so-called open bottle pack ophthalmic container in which the tip portion of the bottle pack ophthalmic container has a tip shape having an inner stopper function and a liquid injection hole 6c is previously formed therein is considered.

[0003]

[Patent Document 1] JP 2001-120639 A

Since eye drops are directly administered to the eye, which is a particularly sensitive organ in the human body, it is strictly required to maintain the sterility until the time of instillation. Therefore, the above-mentioned three-piece eyedrop container is manufactured by sterilizing each member with EO gas, electron beam or γ-ray, and then filling the drug solution. On the other hand, in the case of a bottle pack eye drop container or an open bottle pack eye drop container, since it is integrally molded under a heating condition by a blow molding method or the like, it is possible to fill the drug solution without particularly sterilizing the container. However, in any case, since the drug solution needs to be filled in the eyedrop container in a sterilized state, it is strict after sterilization by a steam sterilization method or a filtration sterilization method using a membrane filter. Aseptically fill in a sterile room with well-conditioned conditions. However, according to such a filling method, the filling work is complicated and the work efficiency is low, and a large amount of capital investment is required.

[0005]

With respect to the above-mentioned technique, if after filling the chemical solution, the eye drop containers can be collectively heat sterilized, the sterilization operation can be integrated at one time, and
Eliminates the need for aseptic filling. In this case, the above-mentioned expensive capital investment can be omitted. Also, conventionally, it was necessary to carefully check the sterilization state for each sterilization operation, but if heat sterilization is performed collectively, such inspection work only needs to be performed after the final sterilization work. , Workability will be improved. Therefore, a technique for sterilizing eye drop containers together with a drug solution has been studied for many years, but has not been successful yet, and an eye drop container that enables such a technique is desired. In the three-piece type eyedrop container, generally, the container body and the inner plug are made of different materials. That is, the container body is formed of a soft resin in order to facilitate extrusion of the chemical liquid. The inner plug is formed of a relatively hard resin in order to ensure the constant amount discharge of the chemical liquid. As described above, since the container body and the inner plug are made of different materials and the heat shrinkage ratios of the resin materials are different from each other, when heat sterilization is performed after they are integrally assembled, the inner plug falls off into the container body. Or the assembly margin becomes loose, and it becomes difficult to secure liquid tightness. Further, when the container body and the inner plug are molded with a relatively hard material, the dimensional accuracy in fitting and assembling the both tends to be a problem, and again, a problem tends to occur in securing liquid tightness. . Further, if the container body is rigid, a large force is required to extrude and discharge the chemical liquid, which causes a decrease in operability.

On the other hand, in the case of an integrally molded product such as the bottle pack eye drop container or the open bottle pack eye drop container, since there is no inner plug, there is no problem of dropping the inner plug, but extruding and discharging the chemical solution is easy. It is usually formed of a soft resin in order to improve the moldability and maintain moldability.

However, a container molded from a soft resin is likely to undergo melt deformation during heat sterilization. Therefore, there is a problem in that the shape of the liquid injection hole 6c becomes unstable, and the amount of the eye drop discharge of the liquid medicine varies, which makes it unsuitable for medical purposes.

Therefore, in view of the above-mentioned drawbacks, an object of the present invention is to provide an eye drop container which is easy to manufacture and easy to sterilize, can assure sterility more reliably, and is excellent in eye drop operability.

[0009]

The present inventors have found that the temperature is 121 ° C.
Focusing on the fact that all the bacteria die when heated for 20 minutes, the results of intensive research show that the desired eyedrop container can be formed by integrally molding using a resin material that withstands these conditions and does not melt or deform. The present invention was conceived, thinking that it could be obtained. The characteristic configuration of the eyedrop container of the present invention is that, when sterilized by maintaining it at 121 ° C. for 20 minutes,
The point is that they are integrally molded from a resin material that does not substantially melt or deform.

The resin material is preferably a polypropylene-polyethylene random copolymer, and the polyethylene content of the polypropylene-polyethylene random copolymer is preferably 1 to 10%, particularly 3 to 5%. preferable. In addition, it is preferable that a hollow hollow cylindrical body portion is provided with a hollow portion that can be held by two fingertips.

Further, as an eye drop using such a medical eye drop container, a cap that can be screwed into the medical eye drop container is provided, and a liquid injection cylinder part provided at the tip of the medical eye drop container is provided. It is characterized in that a concave portion having a bottomed conical shape whose inner diameter becomes larger toward the tip side is formed as a recess, and a liquid injection portion is provided at the bottom of this concave portion.

[Effects] As described above, in the conventional eye drop container, for example, the container body and the inner stopper are separately sterilized, and then they are assembled under aseptic conditions, and aseptically filled with the sterilized drug solution. did not become. In this regard, since the eyedrop container of the present invention is integrally molded with a resin material that does not substantially melt or deform when sterilized by maintaining it at 121 ° C. for 20 minutes, 121 ° C. after being filled with the chemical solution, It can be sterilized under the condition of 20 minutes. Therefore, it becomes possible to perform the conventional complicated work process only by one sterilization work after the preparation of the eye drop container and the filling of the drug solution, and the manufacturing work process can be simplified. Further, since such a sterilization treatment is a strict sterilization treatment that is said to kill all ordinary bacteria, sterilization can be surely performed by one sterilization operation.

If polypropylene-polyethylene random copolymer is used as the resin material, not only the heat resistance is high and the above-mentioned sterilization treatment is possible, but even if it is hard, it is relatively flexible so that it can be relatively easily instilled. Since it is a different material, it has high workability, and it is possible to manufacture an eyedrop container in which the container body and the inner stopper are integrally formed with good workability.
The eye drop operability can also be favorably maintained.

Furthermore, the polyethylene content of the polypropylene-polyethylene random copolymer is 1 to 1
By setting the content to 0%, particularly 3 to 5%, it is possible to obtain a resin material having a hardness that is compatible with workability and eye drop workability without impairing the heat resistance described above.

When the eye drop container is provided with a hollow hollow cylindrical body which is flexible and has a recess which can be grasped by two fingertips, the drug solution in the container is administered. ,
Since the hollow portion formed in the body of the container is held by two fingertips, the holding position of the fingertips is stable. Moreover, when the body of the container is pressed, a part of the body that is in contact with the fingertips is already dented, so that a part of the cylindrical body is dented against the elastic restoring force. Compared to when deforming,
The pressing operation force can be reduced. Therefore, while being a simple and inexpensive remodeling that only forms a hollow portion in the hollow cylindrical body, it is easier to hold than a conventional eyedrop container,
Moreover, since the eye drop operability can be improved by reducing the pressing operation force, the drug solution in the container can be accurately and easily administered.

Further, as an eyedropper using the eyedrop container, if the eyedropper is provided with a cap that can be screwed and mounted, the eyedrop container can be screwed and mounted in a hygienic storage state. , It is switched to the non-wearing state in which the cap is removed and the eyedropper can be operated. In the liquid injection cylinder provided at the tip of the medical eye drop container, a concave portion having a conical bottomed shape having a larger inner diameter toward the tip side is formed as a recess, and by providing a liquid injection portion at the bottom of the recess, It has a stopper function and can adjust the amount of one drop at the time of instillation to a constant value.

[0017]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below with reference to the drawings. 1 to 5 show an eyedropper of the present invention mainly used for medical purposes. This eyedropper is a flexible thermoplastic material filled with a predetermined amount of chemical liquid at the same time as blow molding or vacuum forming. It is composed of an eye drop container A made of, and a cap B which is detachably screwed to a male screw 5a formed on the screw cylinder portion 5 of the eye drop container A.

Here, FIG. 1 is a diagram showing a schematic structure of the eyedropper of the present invention, FIG. 2 is a diagram showing a state near the tip of the eyedropper container in a state where the cap and the eyedropper container are separated, and FIG. FIG. 4 is a view showing a state in which the eyedrop container is turned into a state, FIG.
FIG. 4 is a diagram showing a state at the time of dropping administration.

The eye drop container A has a circular bottom portion 1 which is curved inward, and a hollow cylindrical body portion 2 which is continuous with the periphery of the bottom portion 1.
And a cylindrical neck portion 3 continuous with the shoulder portion 2a of the body portion 2.
An annular step 4 that bulges outward in the diametrical direction from the upper position of the neck 3, a screw cylinder 5 having a male screw 5a continuous to the upper side thereof, and a liquid injection continuous to the upper side thereof. It is composed of a liquid injection cylinder 6 having a port 6a.

The constituent material of this eyedrop container A is 121 ° C.
Polypropylene-polyethylene random copolymer, polypropylene, and the like are resin materials that do not melt or deform when they are sterilized by maintaining them for 20 minutes under conditions, and the entire eyedrop container A formed is elastically deformable. These material properties include MI, and the preferable MI is 0.2 to 2.5, and more preferably 0.3 to 1.5.

Further, as the polypropylene-polyethylene random copolymer, a random polymer of propylene containing 1 to 10%, particularly 3 to 5% of ethylene can be applied, and the moldability is sufficient, and the above-mentioned sterilization is performed. It is suitable for the manufacture of eye drop containers because it can withstand the conditions sufficiently.
Further, when polypropylene is applied, it can withstand the above-mentioned sterilization conditions sufficiently, but it may be difficult to mold depending on the shape of the eyedrop container, and thus it is suitable for molding a simple shape eyedrop container.

As shown in FIG. 2, the liquid injection cylinder 6 of the eye drop container A is formed with a bottomed conical recess 6b having a larger inner diameter on the liquid injection port 6a side (tip side). This recess 6b
A liquid injection hole 6c having a small diameter is formed in the liquid injection portion formed at the bottom of the.

The depth of the recess 6b is in the range of 2 to 7 mm,
Preferably in the range 5-7 mm, most preferably 6 mm
And the diameter (base diameter) of the liquid injection port 6a
Is adjusted in the range of φ2 mm to φ4 mm according to the liquidity of the chemical solution. In order to make the volume of one drop constant (adjusted within the range of 25 to 50 μL per volume depending on the purpose), when the surface tension is large, the diameter of the injection port 6a should be reduced to reduce the surface tension. If the liquid is small, the diameter of the liquid injection port 6a is increased. Further, the injection hole 6c has a diameter of 0.1 mm.
It is formed by using a needle having a diameter in the range of mm to φ0.8 mm.
The diameter of the needle is preferably small, most preferably about φ0.2 mm, but if it is too small, it becomes technically difficult. Therefore, a needle in the range of φ0.4 mm to φ0.6 mm is actually used.

Therefore, by appropriately setting the diameter of the liquid injection port 6a, the depth of the concave portion 6b, and the hole diameter of the liquid injection hole 6c, the eye drop is performed in accordance with the pressing operation of the finger of the body portion 2. The amount of droplets ejected from the container A can be controlled to a set amount.

As shown in FIGS. 1 and 4, the body portion 2 of the eye drop container A is formed with a recess portion 7 which can be held by two fingertips, and the recess portion 7 is formed in the body portion. A pair of flat or substantially flat sandwiching surfaces 7 formed at two locations in the circumferential direction of 2 and facing each other across the container axis X.
It is composed of a. Each of the sandwiching surfaces 7a is gently curved with a curvature smaller than that of the other parts of the body portion 2 when viewed in the container axis X direction, and is also viewed in a radial direction orthogonal to the container axis X direction (front view). ), The intermediate portion excluding both end portions in the container axis X direction is formed in a straight line parallel to the container axis X. Of course, the entire surface may be curved.

The cap B is integrally formed with a first sealing convex portion 15 which is fitted into the concave portion 6b of the eyedrop container A to be hermetically sealed when the male screw 5a of the eyedrop container A is screwed. The protrusion amount of the first sealing convex portion 15 is 0.6 to 1.0 mm.
It is a degree. With the above configuration, the cap B can be favorably screwed into the eyedrop container A to be integrated.

The material of this cap B is a polypropylene-polyethylene random copolymer.

[Manufacturing Method of Eye Drop] The manufacturing method of the eye drop of the present invention will be described below in the order of manufacturing the eye drop container and integrating with the cap. A method for manufacturing the eye drop container A before the recess 6b and the liquid injection hole 6c are formed is well known in the art, and will be briefly described with reference to FIG.

As shown in FIG. 8A, the eyedrop container A
Pair of main molding dies 2 having a first cavity 20 for molding a portion in the range from the annular step portion 4 to the bottom portion 1 of
1 and a pair of sub-molding dies 23 having a second cavity 22 for molding the screw cylinder part 5 and the liquid injection cylinder part 6 of the eyedrops container A are placed on top of them in an opened state. From the extruder head 24, a varisson 25 having a predetermined length, which is an elongated hollow tube-shaped semi-molten thermoplastic material, is extruded along the vertical direction through both molds 21 and 23.

Next, as shown in FIG. 8B, the main molding die 21 is closed and operated, and along the molding surface 21a of the main molding die 21 by the blowing action of compressed air or the vacuum action. Mold the ballison 25 while expanding it. In this state, as shown in FIG. 8B, a predetermined amount of liquid (chemical liquid) is filled from the chemical supply pipe 26. When this liquid filling step is completed, as shown in FIG. 8C, the sub-molding die 23 is closed and operated, and along the molding surface of the sub-molding die 23 by the blowing action of compressed air or the vacuum action. The varison 25 is expanded while being molded, and the filled liquid is sealed (enclosed) at the same time as the molding. Then, the work is completed in the step of FIG.

Next, the manufacturing method for forming the conical bottomed concavity 6b and the small diameter injection hole 6c in the injection cylinder 6 which is the tip of the eye drop container A blow-molded or vacuum-formed as described above. explain.

In the manufacturing method of the first method shown in FIGS. 9A to 9D, the metal convex molding die 30 for molding the conical recessed portion 6b having the bottom and the injection hole 6c are formed. The metal needle-shaped mold 31 is used. The convex mold 30 is
At the tip of the mounting shaft 30A, a conical shaped projection 30B for molding a bottomed conical recess 6b and a bowl-shaped (bell-shaped) molding surface 30C for molding the outer peripheral surface of the liquid injection cylinder 6 of the eye drop container A are formed.
And the needle-shaped mold 3
1 is configured by forming a needle-shaped molding protrusion 31B forming a small-diameter injection hole at the tip of the mounting shaft 31A.

In the first manufacturing method, as shown in FIG. 9 (a), a part of the liquid injection cylinder 6 which is the tip of the eye drop container A is heated with a hot air or halogen lamp, a laser beam, or the like. The first heating means C at room temperature or 70 ° C to 150 ° C
Heat to. The heating temperature depends on the material and shape of the eyedrop container A, but is preferably a temperature at which the tip of the eyedrop container A is slightly softened. If the thermoplastic material of the eye drop container A is a soft resin material such as polyethylene, the tip portion will buckle if not heated, so at least the portion formed by the convex forming die 30 should be formed before the forming. It is necessary to heat the heating means C to a temperature at which it does not buckle. However, in the case of a resin material or shape that can withstand buckling, that is, in the case of being able to withstand the pressing of the convex molding die 30 from the container axis X direction, molding is possible even at room temperature.

Next, as shown in FIG. 9B, while the part of the liquid injection cylinder portion 6 of the eye drop container A heated by the first heating means C is not cooled, the convex mold 30 is placed in the container. By pressing from the direction of the axis X, the bottom of the conical recess 6b having a larger inner diameter on the side of the injection hole 6a is formed in the injection cylinder portion 6 of the eye drop container A. At this time, the bowl-shaped molding surface 30C of the convex molding die 30 makes it possible to remove burrs at the time of blow molding that project to the outer peripheral surface of the liquid injection cylinder portion 6 of the eyedrop container A.

The temperature of the convex mold 30 itself is controlled in the range of room temperature to 150 ° C. in accordance with the shape and wall thickness of the liquid injection cylinder 6 of the eyedrop container A to be molded. The heating temperature is preferably as low as possible in consideration of cooling and solidification of the tip of the liquid injection cylinder 6. The convex mold 30 can be easily replaced according to the liquid property of the liquid to be filled.

Next, as shown in FIGS. 9 (c) and 9 (d),
The needle-shaped mold 31 is pressed against the center position of the bottom of the concave portion 6b formed in the liquid injection cylinder portion 6 of the eyedrop container A from the direction of the container axis X, and the eyedrops are applied in accordance with the pressing operation by the fingertip of the body portion 2. A small-diameter injection hole that can control the amount of liquid droplets ejected from the container A to a set amount is formed. In the process of forming the liquid injection hole 6c by the needle-shaped protrusion 31B of the needle-shaped mold 31, a method of operating the needle-shaped protrusion 31B at room temperature and a method of operating the needle-shaped protrusion 31B
A method of heating and then working is proposed. The method to be adopted is the shape of the injection hole 6c or the shape of the recess 6b to be formed,
In addition, it is selected according to other conditions such as the shape and material of the container and the manufacturing cost. When heating is required, the heating temperature is at least the needle-shaped protrusion 31B of the needle-shaped mold 31.
At a temperature at which the resin of the container material melts, 130 ° C to 180
It is preferable to heat in the range of ° C.

The needle-shaped mold 31 is heated by a second heating means D such as high-frequency induction heating, a halogen lamp, warm air, and the like. The mounting shaft 31A, which is the root of the needle-shaped mold 31, is a water jacket or compressed air. It is configured to be cooled by the cooling means E such as. Then, when the needle-shaped mold 31 is cooled to a predetermined temperature, the needle-shaped mold 31 is extracted from the liquid injection cylinder portion 6 of the eyedrop container A molded in the predetermined shape along the container axis X direction. .

The needle-shaped mold 31 may be subjected to surface treatment such as plating, fluororesin coating, or special plating in order to improve the releasability and releasability of the resin.
This surface treatment is preferably one that can withstand high temperatures and does not easily peel off.

Although the container body A can be obtained as described above, on the other hand, the cap B used in the present application is previously obtained by molding it into the predetermined shape described so far.

Now, after the manufacturing of the container body A is completed as described above, at the time of initial mounting when the cap is first mounted on the container body A, the thermoplastic material of the container body A is The cap B is screwed onto the container body A while maintaining plasticity and having a certain degree of plasticity such that the outline outline shape of the container body A does not collapse even when the cap B is screwed. At this time, since the configuration including the first sealing convex portion 15 is adopted on the side of the cap B, the first sealing convex portion 15 is brought into close contact with the concave portion 6b, and its airtight state is secured. .

By adopting the above constitution, it is possible to obtain an eyedrop container which is excellent in hermeticity and easy to use. [Example] According to the above-described embodiment, an eye drop container having a volume of 5 ml was obtained under various molding conditions and sterilization temperature conditions. As a result, the chemical solution extrusion performance shown in Table 1 was obtained in the hollow portion 7.

[0042]

[Table 1]

From this table, when an eye drop container is integrally molded using the above-mentioned resin material, it can withstand a sterilization operation at 121 ° C. for 20 minutes even if a 5 ml container is molded with 1.8 g of resin. It was found that the composition can be easily molded, and the chemical liquid extrusion operability in that case can be set to a favorable value of about 10 to 12N. The extrusion operability is measured as follows. : With the eye drop container A containing water, the liquid injection cylinder portion 6 faces downward, and the hollow portion 7 of the eye drop container A.
Confirm that the inside of the liquid injection cylinder 6 excluding the concave portion 6b that holds the central part of the outside surface of the liquid is not filled with water (no air is retained near the liquid injection port 6a). Then, the pressing force required to press the recess 7 by narrowing the interval for holding the eyedrop container and to drop one drop of water from the liquid injection port 6a of the eyedrop container is a digital force gauge. It was measured at. With respect to the extrusion stress, if the extrusion stress is 20 N or more, the user will feel a strong resistance to the fingertip during the eyedropping operation, so it is preferably set to 15 N or less. In addition, with the same resin material as described above,
When an eye drop container that does not have a dent that withstands similar sterilization conditions was formed, the extrusion stress was 35.3 N (3.64 kg).
It was found to be about f), and it was found that the thing of the present invention was extremely excellent in eye drop operability.

[Other Embodiments] In each of the above-described embodiments, the liquid injection cylinder portion 6 of the container body A that has been blow molded or vacuum formed.
In addition, it is possible to control the conical recessed portion 6b having a bottom with a larger inner diameter toward the injection port 6a and the amount of liquid droplets ejected from the container body A in accordance with the pressing operation of the body portion 2 with a fingertip to a set amount. Although the eyedrop container in which the small-diameter injection hole 6c is formed in advance has been described, the present invention is not limited to such an eyedrop container, and as shown in FIG. At the same time, a needle-shaped projection 9 for penetrating and forming a liquid injection hole at the tip of the container body A is formed on the male screw 5a of the container body A made of a flexible thermoplastic material which is filled and sealed with a predetermined amount of liquid medicine.
Cap B which is integrally formed with is detachably screwed,
The cap B has a needle-like projection 9 to form a liquid injection hole 6c in the liquid injection portion at the tip of the container body A by screwing the cap B one step deeper than the normal closed position. I am doing it. Since the other configurations are the same as the configurations described in the embodiment, the same components are denoted by the same reference numerals as those in the embodiment and the description thereof is omitted.

Further, in the above-mentioned embodiment, the eyedrop container having the recessed portion has been described, but the present invention is not limited to this shape, and it can be applied to those without the recessed portion. Can be applied and even
The shape is not limited to a cylindrical shape, but may be an elliptical shape, various forms can be adopted, and the shape is appropriately set based on the resin material used, the application, and the like.

[Brief description of drawings]

FIG. 1 is a diagram showing a schematic configuration of an eyedropper of the present invention.

FIG. 2 is a front sectional view of the vicinity of the tip of the eyedrop container with the cap and the eyedrop container separated.

FIG. 3 is a front cross-sectional view of the vicinity of the tip of the eyedrop container when the cap is screwed into the eyedrop container.

FIG. 4 is an overall side view of the eye drop container.

FIG. 5 is a diagram showing a usage state during drip administration.

FIG. 6 is a view showing an eyedropper having an eyedropper container having an inner stopper.

FIG. 7 is a side sectional view of an eyedrop container configured so that a liquid injection hole can be formed therethrough.

FIG. 8 is a molding process diagram of the eye drop container by blow molding or vacuum molding.

FIG. 9 is a process explanatory view showing the method for manufacturing the eyedropper.

[Explanation of symbols]

A eye drop container B cap T tip 2 torso 6 Injection cylinder 6a Injection port 6b recess 6c Injection hole 7 depression 8a Step portion 8b Tip protrusion 15 1st sealing projection 16 Second sealed protrusion 17 Third guide projection

─────────────────────────────────────────────────── ─── Continued Front Page (51) Int.Cl. ⁷ Identification Code FI Theme Coat (Reference) B65D 1/00 A

Claims (5)

[Claims] 1. A medical eye drop container integrally molded from a resin material that does not melt or deform when maintained at 121 ° C. for 20 minutes for sterilization. 2. The eye drop container for medical use according to claim 1, wherein the resin material is a polypropylene-polyethylene random copolymer. 3. The ophthalmic container for medical use according to claim 2, wherein the polypropylene-polyethylene random copolymer has a polyethylene content of 3 to 5%. 4. The hollow body having a flexible hollow cylindrical shape is provided with a recessed portion that can be held by two fingertips.
The eye drop container for medical use according to any one of 3 above. 5. A cap that can be screwed onto the medical eye drop container according to any one of claims 1 to 4, and a liquid injection cylinder part provided at a distal end of the medical eye drop container,
An eyedropper in which a conical concave portion having a bottom is formed so that the inner diameter becomes larger toward the tip side, and a liquid injection portion is provided at the bottom of the concave portion.