JP2004129723A

JP2004129723A - Syringe serving also as container

Info

Publication number: JP2004129723A
Application number: JP2002295150A
Authority: JP
Inventors: Seiji Shimazaki; 島崎　誠二
Original assignee: ARUTE KK
Current assignee: ARUTE KK
Priority date: 2002-10-08
Filing date: 2002-10-08
Publication date: 2004-04-30
Anticipated expiration: 2022-10-08
Also published as: JP4098593B2

Abstract

<P>PROBLEM TO BE SOLVED: To surely prevent discharge of air bubbles and inert gas from a liquid medicine filled and preserved in a cylinder and remaining of the liquid medicine inside a syringe. <P>SOLUTION: The subject syringe 10 serving also as a container is provided with front and rear stoppers 14 and 15 airtightly and liquidtightly inserted with an interval at the front and back in the axial direction inside the cylinder 11 provided with a cylinder tip member 12 and a finger grip 13 on front and rear ends, and the liquid medicine M is filled and kept between the front and rear stoppers 14 and 15 inside the cylinder 11. The rear end 14b of the front stopper 14 is formed as a conical projection part 14c and the front end 15a of the rear stopper 15 is formed as a conical recessed part 15b to which the projection part 14c of the front stopper 14 is to be fitted. The vertex angle (α) of the conical surface 14d of the projection part 14c of the front part stopper 14 is set to 90° to 170° and the vertex angle β of the conical surface 15e of the recessed part 15b of the rear part stopper 15 is set slightly larger than the vertex angle α. <P>COPYRIGHT: (C)2004,JPO

Description

【０００１】
【発明の属する技術分野】
本発明は、薬液を予め充填、保管しておき使用時に包装から取り出して直ぐに使用することができる容器兼用注射器に関するものである。
【０００２】
【従来の技術】
前記容器兼用注射器は、病医院内において煩雑な操作をすることなく、包装から取り出して直ぐに使用できるので、利便性に優れ、医師や看護婦の作業の軽減に大変に役立ち、このため、多くの病医院で採用されるようになって来ている。
従来の容器兼用注射器は、図３に示すように、容器兼用注射器１の本体となる円筒状のシリンダ２の中に、２個またはそれ以上の個数のゴムまたは軟質のプラスチックスのように弾力性のある材質で製作した円柱状の前、後部ストッパー３，４が、気密、液密にかつシリンダ２の軸方向に摺動可能に挿入されると共に、前記前、後部ストッパー３，４間に薬液Ｍが充填されて安全に保管することができるようになっている。そして、前記シリンダ２の先端には先端側に注射針５を取り付ける筒先６ａを設けたハブ（筒先部材）６が気密、液密に嵌着され、シリンダ２の後端にはフィンガーグリップ７が嵌着されている。前記ハブ６の後端側の内部には、前記前部ストッパー３の外径より若干大きい内径を有し、かつ前部ストッパー３の長さより若干長い軸長を有するバイパスチャンバー６ｂが設けられ、該バイパスチャンバー６ｂの内壁６ｃと底部６ｄに１本または複数本の軸方向の縦溝６ｅと直径方向の横溝６ｆが前記筒先６ａの内孔６ｇに連絡して設けられており、前記シリンダ２の後端から挿入して前記後部ストッパー４に螺合したプランジャロッド８を介して前記後部ストッパー４を押し込むと、前、後部ストッパー３，４間のシリンダ２内に保管されていた薬液Ｍが前方へ移動して、前部ストッパー３が前記バイパスチャンバー６ｂ内に入り込むことによって、密閉が解除されてシリンダ２内の薬液Ｍが前記縦溝６ｅと横溝６ｆを通って前記筒先６ａの内孔６ｇに流れて注射針５に導かれるようになっている。
【０００３】
前記容器兼用注射器１では、前記プランジャーロッド８を押すことにより薬液Ｍを介して前部ストッパー３がシリンダ２内からハブ６のバイパスチャンバー６ｂ内に押し出されて密閉が解除されるまでは、筒先６ａには薬液Ｍが到達しないので、注射針５やそのキャップ９等であっても外部の細菌から重要な部分を守る策が施されているならば、どのような部品でも筒先６ａに取り付けておける利便性があるため、事前に注射針５を取り付けておける容器兼用注射器の構造として最も適したものということができる（例えば、特許文献１，特許文献２、特許文献３）。
【０００４】
【特許文献１】
特公昭６２−５８７４５号公報
【特許文献２】
特公平４−４６１５２号公報
【特許文献３】
特開２００２−１７７３９１号公報
【０００５】
【発明が解決しようとする課題】
しかしながら、前記容器兼用注射器１では、注射をするにあたり、前記前部ストッパー３を前記シリンダ２からハブ６のバイパスチャンバー６ｂ内に押し出して注射の準備を進める際、シリンダ２内に保存してあった薬液Ｍの中に残留していた気泡または窒素などの不活性ガスを先行して外部へ放出する必要があるが、前記前部ストッパー３の後面３ａや後部ストッパー４の前面４ａの薬液Ｍと接する接液部分が、シリンダ２の軸に垂直な平滑面であるために、前部ストッパー３が前記バイパスチャンバー６ｂに入った後、後部ストッパー４が薬液Ｍを押圧することにより、該薬液Ｍが前記バイパスチャンバー６ｂの外周側の縦溝６ｅに押し込まれても、前、後部ストッパー３，４の中心部側にある前記気泡や不活性ガスは容易に外周側に移動して前記縦溝６ｅ内に入り込むことができず、したがって、薬液Ｍ内にある前記気泡や不活性ガスを縦溝６ｅから横溝６ｆ、筒先６ａの内孔６ｇおよび注射針５を通して容易に外部に放出することができない問題があった。また、前記前、後部ストッパー３，４はゴム製であるために、シリンダ２を形成するガラスやプラスチックス等と比べて前記気泡や不活性ガスが周囲面に付着しやすく、この点からも前記気泡や不活性ガスが前記筒先５ａに装着した注射針４から容易に外部へ放出することができない問題があった。これは、注射前の準備に手間取る不便を生じることとなり、容器兼用注射器の利便性を逆に損なう結果となっている。
【０００６】
本発明は、上記事情に鑑みてなされたものであって、容器兼用注射器による注射の準備を進める際、容器兼用注射器のシリンダに保存してあった薬液の中の気泡や不活性ガスを注射針を通して容易に外部へ放出することができると共に、注射終了時に注射器内に薬液が残留するのを防止することができる容器兼用注射器を提供することを目的とする。
【０００７】
【課題を解決するための手段】
本発明は、前記課題を解決するために、以下の点を特徴としている。
すなわち、請求項１に係る容器兼用注射器は、筒状のシリンダと、該シリンダの先端および後端にそれぞれ設けられた筒先部材およびフィンガーグリップと、前記シリンダ内に、その軸方向の前後に間隔をあけて気密、液密に挿入された複数個のストッパーとを備え、前記シリンダ内における複数のストッパー間の空間に薬液が充填、保管される容器兼用注射器において、前記ストッパーのうち、前側に配置された前部ストッパーは、その後端が凸部として形成され、前部ストッパーの後方に隣接して配置された後部ストッパーは、その前端が前記前部ストッパーの凸部が嵌入される凹部として形成され、かつ該凹部はストッパーの直径方向の中心から外周側に行くにしたがって前記前部ストッパーの凸部との間隔が徐々に広がる凹面を有していることを特徴とする。
【０００８】
前記容器兼用注射器においては、注射の事前準備時に、シリンダの筒先を上に向け、後部ストッパーを前方へ押すと、シリンダ内に充填、保管されていた薬液中の気泡や不活性ガスが薬液の上部に移動し、前部ストッパーの凸部の傾斜している斜面に沿ってシリンダの内周面側に移動を仕向けられ、かつ該内周面に沿って浮上され、筒先部材の薬液通路を経て薬液が注出される前に容易に外部へ放出される。また、注射時の終了時に、前部ストッパーの凸部と後部ストッパーの凹部とが、それらの中心側から外周側へ向けて徐々に接触して行くことにより、前、後部ストッパー間にある薬液は、シリンダの内周面に押し出されて前記筒先部材内に導入され、これにより、容器兼用注射器内に残留することなく、筒先部材の薬液通路を経て外部へ押し出される。
【０００９】
請求項２に係る容器兼用注射器は、請求項１に記載の容器兼用注射器において、前記前部ストッパーの凸部は円錐形とされ、前記後部ストッパーの凹部における凹面は円錐面とされていることを特徴とする。
【００１０】
請求項３に係る容器兼用注射器は、請求項２に記載の容器兼用注射器において、前記前部ストッパーの凸部における円錐面の頂角が９０°〜１７０°に設定され、前記後部ストッパーの凹部における円錐面の頂角が前部ストッパーの凸部における円錐面の頂角より僅かに大きく設定されていることを特徴とする。
【００１１】
【発明の実施の形態】
以下、本発明の一実施の形態に係る容器兼用注射器について図１、図２を参照して説明する。
図１において、１０は本発明の一実施の形態に係る容器兼用注射器である。該容器兼用注射器１０は、ガラスまたはプラスチックス製の円筒状（筒状）のシリンダ１１と、該シリンダ１１の先端に嵌着して設けられたハブ（筒先部材）１２と、シリンダ１１の後端に設けられたフィンガーグリップ１３と、前記シリンダ１１の前後端の内部に気密、液密に、かつ軸方向に摺動可能に挿入された前部ストッパー１４および後部ストッパー１５と、前記シリンダ１１の後端側からシリンダ１１内に先端側を挿入されて後部ストッパー１５に連結されたプランジャロッド１６とを備えている。
そして、前記シリンダ１１内にその軸方向に間隔をあけて配置された前記前部ストッパー１４と後部ストッパー１５との間の空間に薬液Ｍが充填、保管されるようになっている。
【００１２】
前記ハブ１２は、円筒状部１２ａの先端側に注射針取付部１２ｂを設け、後端側に大径の装着部１２ｃを設けてなり、前記装着部１２ｃが前記シリンダ１１の先端外周部に嵌着されている。前記注射針取付部１２ｂは、前記円筒状部１２ａの先端の中心部に設けられ、ルアー・ロック方式による注射針１７の装着部（針もと）１７ａを嵌合させるテーパ筒部（筒先）１８と、円筒状部１２ａの先端の外周側に設けられ、前記注射針１７の装着部１７ａの外周フランジ１７ｂを螺合させるネジ１９ａを内周側に形成したルアー・ロック部１９とを備えている。前記円筒状部１２ａの内部に設けた円筒状のパイパスチャンバー１２ｄは、その直径が前記前部ストッパー１４の直径より若干大きく形成され、内壁１２ｅにシリンダ１１の軸方向に沿う縦溝（薬液通路）２０が周方向に間隔をあけて１個または複数個設けられ、底部１２ｆに縦溝２０を前記テーパ筒部１８の内孔１８ａに連絡させる横溝（薬液通路）２１が設けられている。
【００１３】
前記フィンガーグリップ１３は、円筒状部１３ａの後端部に円筒状部１３ａの直径方向に延びるフランジ１３ｂを一体に形成してなり、前記円筒状部１３ａが前記シリンダ１１の後端の外周部に嵌着されており、前記円筒状部１３ａの内側には、内径が前記後部ストッパー１５の外径より小径で、前記プランジャロッド１６の外径より大径に形成された環状の突条１３ｃが設けられており、前記後部ストッパー１５がシリンダ１１の後端より離脱しないようになっている。
【００１４】
前記前部ストッパー１４は、直径を前記シリンダ１１の内径より僅かに大きくされたゴム製または軟質プラスチックス製等の円筒状部材からなり、外周に周方向に沿う溝が１個または複数設けられると共に、前端１４ａがシリンダ１１の軸方向に略垂直な平面に形成され、後端１４ｂがシリンダ１１に中心に頂点Ｃ１を有する円錐形の凸部１４ｃとして形成されている。また、前部ストッパー１４の後方に隣接して配置された後部ストッパー１５は、前部ストッパー１４と同様に、直径を前記シリンダ１１の内径より僅かに大きくされたゴム製または軟質プラスチックス製等の円筒状部材からなり、外周に周方向に沿う溝が１個または複数設けられると共に、その前端１５ａが、前記前部ストッパ１４ーの凸部１４ｃが嵌入される円錐形の凹部１５ｂとして形成され、後端１５ｃがシリンダ１１の軸方向に略垂直な平面に形成され、後端部に形成されたねじ穴１５ｄに前記プランジャーロッド１６の雄ねじ１６ａが螺合されて前部ストッパー１５とプランジャーロッド１６とが連結されている。
【００１５】
前記前部ストッパー１４における凸部１４ｃの円錐面１４ｄの頂角αは、前記シリンダ１１の内径（前、後部ストッパー１４，１５の外径）によって異なるが、９０°〜１７０°の範囲に設定され、前記後部ストッパー１５における凹部１５ｂの円錐面（凹面）１５ｅの頂角βは、前記頂角αの頂角より僅かに大きく、例えば、２°〜１５°程度大きくに設定されている。一般的には、シリンダ１１の内径が小さい場合には前記頂角αを小さくし、シリンダ１１の内径が大きい場合には頂角αを比較的大きくすることができる。
なお、図１中、２２は前記注射針１７の装着部１７ａに嵌着して使用し、注射針１７を保護する円筒状の注射針カバーである。
【００１６】
前記実施の形態に係る容器兼用注射器１０を使用して注射をする際には、その事前準備として、使用者は、容器兼用注射器１０を注射針１７側を上に向けた状態とし、手指でフィンガーグリップ１３を支えながらプランジャーロッド１６を操作して後部ストッパー１５を、前部ストッパー１４の略長さ分だけ押し込む。これにより、前、後部ストッパー１４，１５間の薬液Ｍがシリンダ１１内の前側へ進められ、これに伴って前記前部ストッパー１４が前進して前記ハブ１２のバイパスチャンバー１２ｄ内に押し込まれる。このとき、前部ストッパー１４による密閉が解除されるので、シリンダ１１内に充填、保管されていた薬液Ｍ内の気泡は、注射針１７側を上に向けた状態であるため、薬液Ｍの上部に浮上集合させられており、前部ストッパー１４が円錐形の凸部１４ｃとされているので、円錐面１４ｄ，１５ｅの外側前方に傾斜している斜面に沿ってシリンダ１１の内周面側に移動を仕向けられ、かつ該内壁面に沿って浮上され、前記のように薬液Ｍが通る前に薬液通路を経て容易に注射針１７の先端から外部へ放出される。次に、注射針１７から注射針カバー２２を外すと、薬液Ｍが、前部ストッパー１４の外周部を迂回してバイパスチャンバー１２ｄの内壁１２ｅの縦溝２０を通り、底部１２ｆの横溝２１から注射針取付部１８の内孔１８ａを経て注射針１７から薬液部内に残る微量の気泡と共に少し押し出される。
【００１７】
前記事前準備が終わった後に、人体の所要部位に注射針１７を穿刺して前記プランジャーロッド１６を更に押し込んで注射を行う。注射の終了間際に至ると、前記ハブ１２のバイパスチャンバー１２ｄ内にある前部ストッパー１４に後部ストッパー１５が接近して前部ストッパー１４の凸部１４ｃが後部ストッパー１５の凹部１５ｂ内に嵌入し、遂に、図２に示すように、前部ストッパー１４の凸部１４ｃの頂部が後部ストッパー１５の凹部１５ｂの最奥部に接触する。このとき、前記凹部１５ｂの円錐面１５ｅの頂角βが凸部１４ｃの円錐面１４ｄの頂角αより大きくなっているので、前記凹部１５ｂが後部ストッパー１５の直径方向の中心から外周側に行くにしたがって前記前部ストッパー１４の凸部１４ｃとの間隔が徐々に広がる凹面を有することとなり、前記凸部１４ｃと凹部１５ｂとの間に前記シリンダ１１の中心の周りに外側が開放された三角形状の断面を有する環状空間Ｅが形成された状態となる。
【００１８】
この状態から、更にプランジャーロッド１６を介して後部ストッパー１５を強く押すと、後部ストッパー１５が弾性変形して最奥部から外周側へ向けて徐々に前部ストッパー１４の円錐面１４ｄに接触して行き、前部ストッパー１４の凸部１４ｃと後部ストッパー１５の凹部１５ｂとの間にある薬液が前、後部ストッパー１４，１５の外周側に押し出される。この押し出された薬液は前記ハブ１２のバイパスチャンバー１２ｄの縦溝２０、横溝２１に導きかれ、ハブ１２のテーパ筒１８の内孔１８ａを経て注射針１７から注射部位に注入される。これにより、容器兼用注射器１０内に薬液Ｍを残すことなく注射をすることができる。
【００１９】
このように、前記実施の形態に係る容器兼用注射器１０によれば、前記シリンダ１１内に、その軸方向の前後に間隔をあけて気密、液密に、かつ軸方向に摺動可能に挿入され、シリンダ１１内に充填、保管される薬液Ｍを密封する前、後部ストッパー１４，１５において、前部ストッパー１４は、その後端１４ｂが頂角αを９０°〜１７０°に設定した円錐形の凸部１４ｃとして形成され、前部ストッパー１４の後方に隣接して配置された後部ストッパー１５は、その前端１５ａが前記前部ストッパー１４の凸部１４ｃが嵌入される、頂角βを前記頂角αより僅かに大きくした円錐面１５ｅに設定した凹部１５ｂとして形成されているので、注射の事前準備時にはシリンダ１１内に充填、保管されていた薬液Ｍの中の気泡や不活性ガスを効果的に注射針１７から外部へ放出することができ、また、注射時には容器兼用注射器１０内に薬液Ｍを残すことなく確実に容器兼用注射器１０から押し出して注射の用に無駄なく供することができる。しかも、前記前、後部ストッパー１４，１５は、それらの後端１４ｂと前端１５ａにそれぞれ円錐形の凸部１４ｃと凹部１５ｂを形成するものであるので、構造も比較的簡単であり、容易に製造することができる。
【００２０】
前記前、後部ストッパー１４，１５の凸部１４ｃ、凹部１５ｂの円錐面１４ｄ，１５ｅの頂角α、βは、前記数値の範囲に設定するのが好まく、前記設定数値の範囲より大きくすると、前記凸部１４ｃと凹部１５ｂの円錐面１４ｄ，１５ｅが前記シリンダ１１の軸方向に垂直な平面に近づくため、前記薬液Ｍ中の気泡や不活性ガスの外部への放出効果と、容器兼用注射器１０内への薬液残留の防止効果とを期待することができず、また、前記設定数値の範囲より小さくすると、前記凸部１４ｃの長さと凹部１５ｂの深さが大きくなり、必然的に前、後部ストッパー１４，１５の軸方向の長さが大きくなるので、容器兼用注射器１０の大きくなるか、容器兼用注射器１０を大きくしなければ、シリンダ１１内に充填、保管する薬液Ｍの容量が少なくなる。
【００２１】
なお、前記実施の形態に係る容器兼用注射器１０においては、前記前、後部ストッパー１４，１５の凸部１４ｃ、凹部１５ｂをそれぞれ円錐面１４ｄ，１５ｅに形成したが、本発明はこれに限らず、球面、楕円面等の曲面に形成することもできる。この場合も、前部ストッパー１４の凸部の凸面の曲率半径に対して後部ストッパー１５の凹部の凹面の曲率半径を所定量だけ大きくし、後部ストッパー１５の凹部がその直径方向の中心から外周側に行くにしたがって前部ストッパー１４の凸部との間隔が徐々に広がる凹面を有するようにすることは勿論である。また、前記実施の形態に係る容器兼用注射器１０は、本発明をシリンダ１１の前後端にルアー・ロック形式のハブ１２とフィンガーグリップ１３をそれぞれ嵌着した形式の容器兼用注射器に適用した例であるが、本発明はこれに限らず、前記シリンダ１１とフィンガーグリップ１３を一体に形成したものにも適用でき、さらに、前記ハブ１２は、ルアー・ロック形式のものに限らず、図３に示した従来の容器兼用注射器１のハブ６と同様な形式、その他の形式のものであってもよい。
【００２２】
【発明の効果】
以上説明したように、本発明によれば以下の優れた効果を奏する。
請求項１に係る容器兼用注射器によれば、シリンダ内にその軸方向の前後に間隔をあけて気密、液密に挿入され、シリンダ内に充填、保管される薬液を密封する複数のストッパーにおいて、前部ストッパーは、その後端が凸部として形成され、前部ストッパーの後方に隣接して配置された後部ストッパーは、その前端が前記前部ストッパーの凸部が嵌入される凹部として形成され、かつ該凹部はストッパーの直径方向の中心から外周側に行くにしたがって前記前部ストッパーの凸部との間隔が徐々に広がる凹面を有している構成とされているので、注射の事前準備時にはシリンダ内に充填、保管されていた薬液の中の気泡や不活性ガスを効果的に注射針から外部へ放出することができ、また、注射時には容器兼用注射器内に薬液を残すことなく確実に容器兼用注射器から押し出して無駄なく注射の用に供することができる。
【００２３】
請求項２に係る容器兼用注射器によれば、前部ストッパーの凸部が円錐形とされ、後部ストッパーの凹部における凹面が円錐面とされているので、前記請求項１に係る容器兼用注射器による効果を奏することができる上に、構造も比較的簡単であり、容易に製造することができる。
【００２４】
請求項３に係る容器兼用注射器によれば、前部ストッパーの凸部における円錐面の頂角が９０°〜１７０°に設定され、後部ストッパーの凹部における円錐面の頂角が前部ストッパーの凸部における円錐面の頂角より僅かに大きく設定されているので、前記請求項１に係る容器兼用注射器によるシリンダ内薬液中の気泡や不活性ガスの外部への放出効果と、容器兼用注射器内への薬液残留の防止効果を一層効果的に行わせることができる。
【図面の簡単な説明】
【図１】本発明に一実施の形態に係る容器兼用注射器を示す縦断面図である。
【図２】本発明に一実施の形態に係る容器兼用注射器による注射終了時における前、後部ストッパーの動作位置を示す縦断面図である。
【図３】従来の容器兼用注射器の一例を示す縦断面図である。
【符号の説明】
１，１０　容器兼用注射器
２，１１　シリンダ
３，１４　前部ストッパー
３ａ，１４ｂ　後端
４，１５　後部ストッパー
４ａ，１５ａ　前端
５，１７　注射針
６，１２　ハブ
６ａ，１２ｄ　バイパスチャンバー
６ｅ，２０　縦溝（薬液通路）
６ｆ，２１　横溝（薬液通路）
７，１３　フィンガーグリップ
８，１６　プランジャーロッド
１４ｃ　凸部
１４ｄ　円錐面
１５ｂ　凹部
１５ｅ　円錐面（凹面）
Ｃ１，Ｃ２　頂点
Ｅ　環状間隙
Ｍ　薬液
α、β　頂角[0001]
TECHNICAL FIELD OF THE INVENTION
TECHNICAL FIELD The present invention relates to a container / syringe that can be filled and stored in advance with a drug solution and used immediately after taking out of a package at the time of use.
[0002]
[Prior art]
The container-and-syringe can be used immediately after taking it out of the packaging without complicated operations in the hospital and clinic, so it is excellent in convenience and very useful for reducing the work of doctors and nurses. It is being adopted by hospitals and clinics.
As shown in FIG. 3, a conventional container / injection syringe has elasticity such as two or more rubber or soft plastics in a cylindrical cylinder 2 serving as a main body of a container / injection syringe 1. Column-shaped front and rear stoppers 3 and 4 made of a material having airtightness are inserted air-tightly and liquid-tightly and slidably in the axial direction of the cylinder 2, and a chemical solution is interposed between the front and rear stoppers 3 and 4. M is filled and can be stored safely. A hub (cylinder tip member) 6 provided with a cylinder tip 6a for attaching the injection needle 5 to the tip end of the cylinder 2 is air-tightly and liquid-tightly fitted. A finger grip 7 is fitted to the rear end of the cylinder 2. Is being worn. Inside the rear end side of the hub 6, a bypass chamber 6b having an inner diameter slightly larger than the outer diameter of the front stopper 3 and having an axial length slightly longer than the length of the front stopper 3 is provided. One or more axial longitudinal grooves 6e and diametrical lateral grooves 6f are provided in the inner wall 6c and the bottom 6d of the bypass chamber 6b so as to communicate with the inner hole 6g of the cylinder tip 6a. When the rear stopper 4 is pushed through the plunger rod 8 inserted from the end and screwed to the rear stopper 4, the chemical solution M stored in the cylinder 2 between the front and rear stoppers 3, 4 moves forward. When the front stopper 3 enters the bypass chamber 6b, the hermetic seal is released, and the chemical solution M in the cylinder 2 passes through the vertical groove 6e and the horizontal groove 6f. Is guided to the needle 5 flows into the inner hole 6g of.
[0003]
In the container-and-syringe 1, the plunger rod 8 is pushed to push the front stopper 3 from the inside of the cylinder 2 into the bypass chamber 6 b of the hub 6 via the drug solution M, and the sealing is released until the sealing is released. Since the drug solution M does not reach 6a, any part of the injection needle 5 or its cap 9 can be attached to the cylinder tip 6a if measures are taken to protect important parts from external bacteria. Therefore, it can be said that it is most suitable as a structure of a container / syringe to which the injection needle 5 can be attached in advance (for example, Patent Literature 1, Patent Literature 2, Patent Literature 3).
[0004]
[Patent Document 1]
JP-B-62-58745 [Patent Document 2]
Japanese Patent Publication No. 4-46152 [Patent Document 3]
JP-A-2002-177391
[Problems to be solved by the invention]
However, in the case of the container / syringe 1, when the injection is performed, the front stopper 3 is stored in the cylinder 2 when pushing out the front stopper 3 from the cylinder 2 into the bypass chamber 6b of the hub 6 to prepare for injection. It is necessary to first release bubbles or an inert gas such as nitrogen remaining in the chemical solution M to the outside, but it comes into contact with the chemical solution M on the rear surface 3a of the front stopper 3 or the front surface 4a of the rear stopper 4. Since the liquid contact portion is a smooth surface perpendicular to the axis of the cylinder 2, after the front stopper 3 enters the bypass chamber 6b, the rear stopper 4 presses the chemical liquid M, whereby the chemical liquid M Even if it is pushed into the vertical groove 6e on the outer peripheral side of the bypass chamber 6b, the air bubbles and inert gas at the center of the front and rear stoppers 3, 4 are easily transferred to the outer peripheral side. As a result, the gas and the inert gas in the chemical solution M cannot easily enter the vertical groove 6e from the vertical groove 6e to the outside through the horizontal groove 6f, the inner hole 6g of the barrel 6a, and the injection needle 5. There was a problem that could not be released. In addition, since the front and rear stoppers 3 and 4 are made of rubber, the air bubbles and the inert gas are more likely to adhere to the peripheral surface than the glass or plastics forming the cylinder 2. There has been a problem that air bubbles and inert gas cannot be easily discharged outside from the injection needle 4 attached to the cylinder tip 5a. This results in inconvenience in preparation before injection, which results in a loss of convenience of the combined use syringe.
[0006]
The present invention has been made in view of the above circumstances, and when preparing for injection using a combined container syringe, bubbles and inert gas in a drug solution stored in a cylinder of a combined container syringe are injected with an injection needle. It is an object of the present invention to provide a container / syringe that can be easily released to the outside through a syringe, and that can prevent a drug solution from remaining in the syringe at the end of injection.
[0007]
[Means for Solving the Problems]
The present invention has the following features to solve the above problems.
In other words, the container / syringe according to claim 1 has a cylindrical cylinder, cylinder tip members and finger grips respectively provided at the front end and the rear end of the cylinder, and an interval in the cylinder in the axial direction. A plurality of stoppers that are opened in a gas-tight and liquid-tight manner are provided, and the space between the plurality of stoppers in the cylinder is filled with a drug solution, and in a container dual-purpose syringe that is stored, the stopper is disposed on the front side of the stoppers. The front stopper has a rear end formed as a convex portion, and the rear stopper disposed adjacent to and behind the front stopper has a front end formed as a concave portion into which the convex portion of the front stopper is fitted. And the concave portion has a concave surface in which the distance from the convex portion of the front stopper gradually increases toward the outer peripheral side from the center in the diameter direction of the stopper. And said that you are.
[0008]
In the above-mentioned combined use syringe, at the time of preparation for injection, when the cylinder tip of the cylinder is turned upward and the rear stopper is pushed forward, air bubbles and inert gas in the drug solution filled and stored in the cylinder are located above the drug solution. Move to the inner peripheral surface side of the cylinder along the inclined slope of the convex portion of the front stopper, and float along the inner peripheral surface, and pass through the chemical liquid passage of the cylinder member to pass the chemical liquid. Is easily released to the outside before being poured. Also, at the end of the injection, the convex portion of the front stopper and the concave portion of the rear stopper gradually contact from the center side to the outer peripheral side thereof, so that the drug solution between the front and rear stoppers is Then, it is pushed out to the inner peripheral surface of the cylinder and introduced into the cylinder tip member, so that it is pushed out through the liquid medicine passage of the cylinder tip member to the outside without remaining in the container / syringe.
[0009]
According to a second aspect of the present invention, there is provided a container / syringe device according to the first aspect, wherein the convex portion of the front stopper has a conical shape, and the concave surface of the concave portion of the rear stopper has a conical surface. Features.
[0010]
The container / syringe according to claim 3 is the container / syringe according to claim 2, wherein the apex angle of the conical surface in the convex portion of the front stopper is set to 90 ° to 170 °, and in the concave portion of the rear stopper. The apex angle of the conical surface is set to be slightly larger than the apex angle of the conical surface in the convex portion of the front stopper.
[0011]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, a container / syringe according to an embodiment of the present invention will be described with reference to FIGS.
In FIG. 1, reference numeral 10 denotes a container / syringe according to an embodiment of the present invention. The container / injector 10 includes a cylindrical (cylindrical) cylinder 11 made of glass or plastics, a hub (cylinder tip member) 12 fitted to the tip of the cylinder 11, and a rear end of the cylinder 11. A front grip 14 and a rear stopper 15 which are inserted into the front and rear ends of the cylinder 11 in an air-tight, liquid-tight, and slidable manner in the axial direction. A plunger rod 16 is inserted into the cylinder 11 from the end and connected to the rear stopper 15.
The space between the front stopper 14 and the rear stopper 15, which are arranged in the cylinder 11 at intervals in the axial direction, is filled with the chemical liquid M and stored.
[0012]
The hub 12 is provided with an injection needle mounting portion 12b on the distal end side of the cylindrical portion 12a and a large-diameter mounting portion 12c on the rear end side, and the mounting portion 12c is fitted on the outer peripheral portion of the distal end of the cylinder 11. Is being worn. The injection needle mounting portion 12b is provided at the center of the distal end of the cylindrical portion 12a, and is a tapered cylindrical portion (cylinder tip) 18 into which a mounting portion (needle base) 17a of the injection needle 17 by a luer lock method is fitted. And a luer lock portion 19 provided on the outer peripheral side of the distal end of the cylindrical portion 12a and formed on the inner peripheral side with a screw 19a for screwing the outer peripheral flange 17b of the mounting portion 17a of the injection needle 17 therethrough. . The cylindrical bypass chamber 12d provided inside the cylindrical portion 12a is formed to have a diameter slightly larger than the diameter of the front stopper 14, and a vertical groove (chemical solution passage) along the axial direction of the cylinder 11 on the inner wall 12e. One or a plurality of grooves 20 are provided at intervals in the circumferential direction, and a horizontal groove (chemical solution passage) 21 for connecting the vertical groove 20 to the inner hole 18a of the tapered cylindrical portion 18 is provided on the bottom 12f.
[0013]
The finger grip 13 is formed integrally with a flange 13b extending in the diameter direction of the cylindrical portion 13a at a rear end portion of the cylindrical portion 13a. An annular ridge 13c is fitted inside the cylindrical portion 13a and has an inner diameter smaller than the outer diameter of the rear stopper 15 and larger than the outer diameter of the plunger rod 16. The rear stopper 15 does not come off from the rear end of the cylinder 11.
[0014]
The front stopper 14 is made of a cylindrical member made of rubber or soft plastics whose diameter is made slightly larger than the inner diameter of the cylinder 11, and one or more grooves along the circumferential direction are provided on the outer periphery. The front end 14a is formed in a plane substantially perpendicular to the axial direction of the cylinder 11, and the rear end 14b is formed as a conical convex portion 14c having a vertex C1 at the center of the cylinder 11. Similarly to the front stopper 14, the rear stopper 15 disposed adjacent to the rear of the front stopper 14 is made of rubber or soft plastics whose diameter is slightly larger than the inner diameter of the cylinder 11. It is formed of a cylindrical member, and one or more circumferential grooves are provided on the outer circumference, and a front end 15a thereof is formed as a conical concave portion 15b into which the convex portion 14c of the front stopper 14 is fitted. The rear end 15c is formed in a plane substantially perpendicular to the axial direction of the cylinder 11, and the male screw 16a of the plunger rod 16 is screwed into a screw hole 15d formed in the rear end, so that the front stopper 15 and the plunger rod 16 are connected.
[0015]
The vertex angle α of the conical surface 14d of the convex portion 14c in the front stopper 14 varies depending on the inner diameter of the cylinder 11 (the outer diameter of the front and rear stoppers 14, 15), but is set in the range of 90 ° to 170 °. The vertex angle β of the conical surface (concave surface) 15e of the concave portion 15b of the rear stopper 15 is set slightly larger than the vertex angle of the vertex angle α, for example, about 2 ° to 15 °. Generally, when the inner diameter of the cylinder 11 is small, the apex angle α can be reduced, and when the inner diameter of the cylinder 11 is large, the apex angle α can be relatively large.
In FIG. 1, reference numeral 22 denotes a cylindrical injection needle cover which is used by fitting to the mounting portion 17a of the injection needle 17 and protects the injection needle 17.
[0016]
When performing an injection using the container / syringe 10 according to the above-described embodiment, as a preliminary preparation, the user sets the container / syringe 10 with the injection needle 17 facing upward, and fingers the finger. By operating the plunger rod 16 while supporting the grip 13, the rear stopper 15 is pushed in by a substantial length of the front stopper 14. As a result, the chemical liquid M between the front and rear stoppers 14 and 15 is advanced to the front side in the cylinder 11, and accordingly, the front stopper 14 advances and is pushed into the bypass chamber 12d of the hub 12. At this time, since the sealing by the front stopper 14 is released, the bubbles in the drug solution M filled and stored in the cylinder 11 are in a state where the injection needle 17 side is directed upward. The front stopper 14 is formed as a conical convex portion 14c, so that the front stopper 14 is formed on the inner peripheral surface side of the cylinder 11 along a slope inclined forward and outward of the conical surfaces 14d and 15e. It is directed to move and floats along the inner wall surface, and is easily discharged from the distal end of the injection needle 17 to the outside through the drug solution passage before the drug solution M passes as described above. Next, when the injection needle cover 22 is removed from the injection needle 17, the liquid medicine M bypasses the outer peripheral portion of the front stopper 14, passes through the vertical groove 20 of the inner wall 12e of the bypass chamber 12d, and is injected from the horizontal groove 21 of the bottom portion 12f. It is slightly pushed out from the injection needle 17 through the inner hole 18a of the needle mounting portion 18 together with a small amount of air bubbles remaining in the liquid medicine part.
[0017]
After the preparation is completed, an injection needle 17 is punctured into a required part of the human body, and the plunger rod 16 is further pushed to perform injection. Immediately before the end of the injection, the rear stopper 15 approaches the front stopper 14 in the bypass chamber 12d of the hub 12, and the projection 14c of the front stopper 14 fits into the recess 15b of the rear stopper 15, Finally, as shown in FIG. 2, the top of the projection 14 c of the front stopper 14 contacts the deepest part of the recess 15 b of the rear stopper 15. At this time, since the vertex angle β of the conical surface 15e of the concave portion 15b is larger than the vertex angle α of the conical surface 14d of the convex portion 14c, the concave portion 15b goes from the diametric center of the rear stopper 15 to the outer peripheral side. Accordingly, the front stopper 14 has a concave surface in which the distance between the convex portion 14c and the convex portion 14c gradually increases, and a triangular shape having an outside open around the center of the cylinder 11 between the convex portion 14c and the concave portion 15b. An annular space E having a cross section of?
[0018]
In this state, when the rear stopper 15 is further strongly pushed through the plunger rod 16, the rear stopper 15 is elastically deformed and gradually comes into contact with the conical surface 14d of the front stopper 14 from the innermost portion to the outer peripheral side. The chemical solution between the convex portion 14c of the front stopper 14 and the concave portion 15b of the rear stopper 15 is pushed to the outer peripheral side of the front and rear stoppers 14, 15. The extruded liquid medicine is guided to the vertical groove 20 and the horizontal groove 21 of the bypass chamber 12 d of the hub 12, and is injected from the injection needle 17 to the injection site through the inner hole 18 a of the tapered cylinder 18 of the hub 12. Thereby, the injection can be performed without leaving the drug solution M in the container / syringe 10.
[0019]
As described above, according to the container / syringe 10 according to the embodiment, the airtight, liquidtight, and axially slidably inserted into the cylinder 11 with an interval in front and rear in the axial direction. Before sealing the liquid medicine M filled and stored in the cylinder 11, the front stopper 14 of the rear stoppers 14 and 15 has a conical protrusion whose rear end 14b has an apex angle α of 90 ° to 170 °. The rear stopper 15, which is formed as a portion 14c and is disposed adjacent to and behind the front stopper 14, has a front end 15a at which the convex portion 14c of the front stopper 14 is fitted. Since it is formed as a recess 15b set in a slightly larger conical surface 15e, air bubbles and inert gas in the drug solution M that has been filled and stored in the cylinder 11 at the time of preparation for injection can be effectively removed. It can be discharged from the injection needle 17 to the outside, and can be reliably pushed out of the combined container syringe 10 without leaving the drug solution M in the combined syringe 10 during injection, and can be used for injection without waste. In addition, since the front and rear stoppers 14 and 15 have conical convex portions 14c and concave portions 15b formed at the rear end 14b and the front end 15a, respectively, the structure is relatively simple and easy to manufacture. can do.
[0020]
It is preferable that the apex angles α and β of the convex portions 14c of the front and rear stoppers 14 and 15 and the conical surfaces 14d and 15e of the concave portions 15b be set within the above-mentioned numerical ranges. Since the conical surfaces 14d and 15e of the convex portion 14c and the concave portion 15b approach a plane perpendicular to the axial direction of the cylinder 11, the effect of releasing bubbles and inert gas in the chemical solution M to the outside and the effect of the container / syringe 10 The effect of preventing the chemical solution from remaining in the interior cannot be expected, and if it is smaller than the set value range, the length of the convex portion 14c and the depth of the concave portion 15b become large, and the front and rear portions are inevitably increased. Since the axial lengths of the stoppers 14 and 15 increase, the size of the medical solution M to be charged and stored in the cylinder 11 is small unless the size of the container / injector 10 is increased or the size of the container / injector 10 is not increased. It becomes.
[0021]
In the container / syringe 10 according to the embodiment, the projections 14c and the depressions 15b of the front and rear stoppers 14, 15 are formed on the conical surfaces 14d, 15e, respectively. However, the present invention is not limited to this. It can also be formed into a curved surface such as a spherical surface or an elliptical surface. Also in this case, the radius of curvature of the concave surface of the concave portion of the rear stopper 15 is increased by a predetermined amount with respect to the radius of curvature of the convex surface of the convex portion of the front stopper 14, so that the concave portion of the rear stopper 15 is shifted from the center in the diameter direction to the outer peripheral side. Needless to say, a concave surface gradually widens with the convex portion of the front stopper 14 as going to. The container / syringe 10 according to the above-described embodiment is an example in which the present invention is applied to a container / syringe in which a luer-lock type hub 12 and a finger grip 13 are fitted to the front and rear ends of a cylinder 11, respectively. However, the present invention is not limited to this, and can also be applied to a structure in which the cylinder 11 and the finger grip 13 are integrally formed. Further, the hub 12 is not limited to a luer lock type, and is shown in FIG. The same type as the hub 6 of the conventional container / syringe 1 or another type may be used.
[0022]
【The invention's effect】
As described above, according to the present invention, the following excellent effects can be obtained.
According to the container / syringe according to claim 1, in a plurality of stoppers that are hermetically and liquid-tightly inserted into the cylinder at intervals in front and rear in the axial direction, and that seal the drug solution filled and stored in the cylinder, The front stopper has a rear end formed as a convex portion, and the rear stopper disposed adjacent to and behind the front stopper has a front end formed as a concave portion into which the convex portion of the front stopper is fitted, and The concave portion has a concave surface in which the distance from the convex portion of the front stopper gradually increases from the center in the diameter direction of the stopper toward the outer peripheral side. Bubbles and inert gas in the drug solution that has been filled and stored can be effectively released from the injection needle to the outside, and the drug solution must not be left in the container / syringe at the time of injection. Can be provided for use without waste injected extruded from reliably combined container-syringe.
[0023]
According to the container / syringe of the second aspect, the convex portion of the front stopper has a conical shape, and the concave surface of the concave portion of the rear stopper has a conical surface. And the structure is relatively simple, and it can be easily manufactured.
[0024]
According to the container / injection syringe of the third aspect, the apex angle of the conical surface in the convex portion of the front stopper is set to 90 ° to 170 °, and the apex angle of the conical surface in the concave portion of the rear stopper is the convex angle of the front stopper. Since it is set slightly larger than the apex angle of the conical surface in the portion, the effect of discharging bubbles or inert gas in the chemical solution in the cylinder by the container / injector according to claim 1 to the outside, and into the container / injector. Can be more effectively prevented from remaining.
[Brief description of the drawings]
FIG. 1 is a longitudinal sectional view showing a container / syringe according to an embodiment of the present invention.
FIG. 2 is a vertical cross-sectional view showing the operation positions of front and rear stoppers at the end of injection by the container / syringe according to one embodiment of the present invention.
FIG. 3 is a longitudinal sectional view showing an example of a conventional container / syringe.
[Explanation of symbols]
1,10 Syringe for container 2,11 Cylinder 3,14 Front stopper 3a, 14b Rear end 4,15 Rear stopper 4a, 15a Front end 5,17 Injection needle 6,12 Hub 6a, 12d Bypass chamber 6e, 20 Vertical groove ( Chemical passage)
6f, 21 lateral groove (chemical solution passage)
7, 13 Finger grip 8, 16 Plunger rod 14c Convex portion 14d Conical surface 15b Recess 15e Conical surface (concave surface)
C1, C2 Apex E Annular gap M Chemical solution α, β Apex angle

Claims

A cylindrical cylinder, cylinder tip members and finger grips respectively provided at the front end and the rear end of the cylinder, and a plurality of cylinders which are inserted into the cylinder in an airtight and liquid-tight manner at intervals in front and rear in the axial direction. And a liquid injector is filled with a drug solution in a space between the plurality of stoppers in the cylinder, and is stored.
Among the stoppers, the front stopper disposed on the front side has a rear end formed as a convex portion, and the rear stopper disposed adjacent to the rear of the front stopper has a front end having a convex portion of the front stopper. Is formed as a concave portion, and the concave portion has a concave surface in which the distance from the convex portion of the front stopper gradually increases from the diametric center of the stopper toward the outer peripheral side. Container combined with a syringe.

2. The container / syringe according to claim 1, wherein the convex portion of the front stopper has a conical shape, and the concave surface of the concave portion of the rear stopper has a conical surface.

The vertex angle of the conical surface in the convex portion of the front stopper is set to 90 ° to 170 °, and the vertex angle of the conical surface in the concave portion of the rear stopper is slightly smaller than the vertex angle of the conical surface in the convex portion of the front stopper. The container / syringe according to claim 2, which is set to be large.