JP3302520B2 - Body fluid treatment device and priming method for body fluid treatment device - Google Patents
Body fluid treatment device and priming method for body fluid treatment deviceInfo
- Publication number
- JP3302520B2 JP3302520B2 JP32176194A JP32176194A JP3302520B2 JP 3302520 B2 JP3302520 B2 JP 3302520B2 JP 32176194 A JP32176194 A JP 32176194A JP 32176194 A JP32176194 A JP 32176194A JP 3302520 B2 JP3302520 B2 JP 3302520B2
- Authority
- JP
- Japan
- Prior art keywords
- dialysate
- blood
- tube
- inlet
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3643—Priming, rinsing before or after use
- A61M1/3644—Mode of operation
- A61M1/3649—Mode of operation using dialysate as priming or rinsing liquid
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Description
【０００１】[0001]
【産業上の利用分野】本発明は血液透析治療時に、プラ
イミングと返血の際に使用する生理食塩水の代わりに透
析液を使用することのできる体液処理装置と体液処理装
置のプライミング方法に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a body fluid processing apparatus and a priming method for a body fluid processing apparatus which can use a dialysate instead of a physiological saline used for priming and blood return during hemodialysis treatment.
【０００２】[0002]
【従来の技術及び発明が解決しようとする課題】現在、
血液透析治療は透析器の中に透析膜を配置して、血液室
と透析室に区画し、血液室の中に血液、透析液室の中に
透析液を向流により還流させて、血液中の不要物質を透
析液中に移動させることにより実施されている。しかし
ながら、透析器とこれに接続される動静脈側回路に、治
療開始前に生理食塩液をプライミングし、さらに透析器
と動静脈側回路内に導出した血液を返血する際にも生理
食塩液を流し続けるので、多量の生理食塩水を消費しな
ければならなかった。そこで本発明者は、生理食塩水を
使用せずに血液透析器治療を行うことのできる体液処理
装置を鋭意検討した結果次の発明に到達した。2. Description of the Related Art
In hemodialysis treatment, a dialysis membrane is placed in a dialyzer, divided into a blood chamber and a dialysis chamber. Is carried out by moving unnecessary substances into the dialysate. However, the dialyser and the arteriovenous circuit connected thereto are primed with physiological saline before the start of treatment, and the physiological saline is also used when returning the blood drawn into the dialyzer and arteriovenous circuit. , A large amount of saline had to be consumed. The inventor of the present invention has intensively studied a body fluid treatment apparatus capable of performing hemodialysis treatment without using a physiological saline solution, and has reached the following invention.
【０００３】[0003]
【課題を解決するための手段】［１］本発明は、内部に
限外ロ過膜（３）を配置して血液室（１３）と透析液室
（１４）に区画し、前記血液室（１３）の上流側に血液
入口（１５）を形成するとともに下流側に血液出口（１
６）を形成し、前記透析液室（１４）の上流側に透析液
出口（１８）を形成するとともに下流側に透析液入口
（１７）を形成した、透析器（２）と、前記血液入口
（１５）に接続される動脈側回路（４）と、前記血液出
口（１６）に接続される静脈側回路（５）と、前記透析
液入口（１７）に接続される透析液導入チューブ（８）
と、前記透析液出口（１８）に接続される透析液排出チ
ューブ（９）とから構成され、前記動脈側回路（４）の
途中に分岐チューブ（７）を介して前記限外ロ過膜
（３）により逆ロ過された透析液の貯留バッグ（６）を
接続した体液処理装置（１）を提供する。 ［２］本発明は、次の各工程よりなる［１］記載の体液
処理装置（１）のプライミング方法を提供する。 （１）：透析液導入チューブ（８）と透析液排出チュー
ブ（９）の端部を透析装置（１２）に接続し、透析液を
透析装置（１２）より、透析液導入チューブ（８）を経
て透析液室（１４）へプライミングする工程、 （２）：透析液を限外ロ過膜（３）により逆ロ過して、
限外ロ過膜（３）を洗浄する工程、 （３）：透析液を限外ロ過膜（３）により逆ロ過して動
脈側回路（４）、分岐チューブ（７）を経て透析液貯留
バッグ（６）に充填する工程、 （４）：透析液貯留バッグ（６）中の透析液を動脈側回
路（４）を経て血液室（１３）、静脈側回路（５）へプ
ライミングする工程、Means for Solving the Problems [1] In the present invention, an ultrafiltration membrane (3) is disposed inside to provide a blood chamber (13) and a dialysate chamber.
(14) , a blood inlet (15) is formed on the upstream side of the blood chamber (13) , and a blood outlet (1 ) is formed on the downstream side.
6) is formed, the dialysate inlet at a downstream side together with the upstream side to form a dialysate outlet (18) of the dialysis fluid chamber (14)
A dialyzer (2) forming (17) and the blood inlet
An arterial circuit (4) connected to (15) , a venous circuit (5) connected to the blood outlet (16) , and a dialysate introduction tube (8 ) connected to the dialysate inlet (17). )
If the configured from a dialysate outlet tube connected to a dialysate outlet (18) (9), wherein the ultrafiltration membrane through a branch tube (7) in the middle of the arterial circuit (4)
Provided is a bodily fluid treatment device (1) to which a storage bag (6) for a dialysate reversely filtered by (3) is connected. [2] The present invention provides a priming method for a bodily fluid treatment device (1) according to [1], comprising the following steps. (1): The ends of the dialysate inlet tube (8) and the dialysate outlet tube (9 ) are connected to a dialyzer (12) , and the dialysate is introduced from the dialyzer (12) into the dialysate inlet tube (8) . Priming into the dialysate chamber (14) via (2): reverse filtration of the dialysate through the ultrafiltration membrane (3) ,
A step of washing the ultrafiltration membrane (3) , (3): the dialysate is reversely filtered through the ultrafiltration membrane (3 ) and passed through the arterial circuit (4) and the branch tube ( 7). Filling the storage bag (6) , (4): priming the dialysate in the dialysate storage bag (6) via the arterial circuit (4) to the blood chamber (13) and the venous circuit (5) . ,
【０００４】[0004]
【実施例】図１は本発明の体液処理装置１の概略図を示
す。体液処理装置１は透析器２と、これに接続される動
脈側回路４及び静脈側回路５により構成される。透析器
２はハウジング２ａの内部に限外ロ過膜３を配置して、
血液室１３と透析液室１４に区画されている。前記血液
室１３の上流側には血液入口１５が形成されるとともに
下流側に血液出口１６が形成されている。また前記透析
液室１４の上流側には透析液出口１８が形成されるとと
もに下流側に透析液入口１７が形成されている。前記血
液入口１５には動脈側回路４が接続され、前記血液出口
１６には静脈側回路５が接続されている。動脈側回路４
の途中にはチャンバー１０を配置するとともに分岐チュ
ーブ７を介して透析液貯留バッグ６が接続されている。
また静脈側回路５の途中にもチャンバー１１が配置され
ている。前記透析液入口１７には透析液導入チューブ８
が接続され、前記透析液出口１８には透析液排出チュー
ブ９が接続されている。透析液導入チューブ８と透析液
排出チューブ９の他方の端部は透析装置１２に接続され
る。FIG. 1 is a schematic view of a body fluid treatment apparatus 1 according to the present invention. The body fluid treatment device 1 includes a dialyzer 2 and an arterial circuit 4 and a venous circuit 5 connected thereto. The dialyzer 2 has an ultrafiltration membrane 3 disposed inside a housing 2a,
It is partitioned into a blood chamber 13 and a dialysate chamber 14. A blood inlet 15 is formed on the upstream side of the blood chamber 13 and a blood outlet 16 is formed on the downstream side. A dialysate outlet 18 is formed on the upstream side of the dialysate chamber 14, and a dialysate inlet 17 is formed on the downstream side. The artery side circuit 4 is connected to the blood inlet 15, and the vein side circuit 5 is connected to the blood outlet 16. Arterial circuit 4
A dialysis fluid storage bag 6 is connected via a branch tube 7 while a chamber 10 is arranged in the middle of the process.
A chamber 11 is also provided in the vein side circuit 5. The dialysate inlet tube 17 is provided at the dialysate inlet 17.
The dialysate outlet tube 18 is connected to the dialysate outlet tube 18. The other ends of the dialysate introduction tube 8 and the dialysate discharge tube 9 are connected to a dialyzer 12.
【０００５】本発明においては、透析液を限外ロ過膜３
を介して逆ロ過し、動脈側回路４、分岐チューブ７を経
て透析液貯留バッグ６に充填するため、透析器２はでき
るだけ高い限外ロ過能を有するように工夫するのが良
い。（例えばハウジングの形状、構造、限外ロ過膜３の
選択等。） また透析液貯留バッグ６は組み立て時に動脈側回路４に
一体に接続しても良いし、使用時に動脈側回路４に接続
しても良い。透析液貯留バッグ６の容量は５００−ｍｌ
（ミリリットル）から２−ｌ（リットル）に設定され、
治療目的に応じて自由に設定することができる。[0005] In the present invention, the dialysate is added to the ultrafiltration membrane 3.
, And the dialysate 2 is filled into the dialysate storage bag 6 via the arterial circuit 4 and the branch tube 7, so that the dialyzer 2 should be devised so as to have the highest possible ultrafiltration capacity. (For example, the shape and structure of the housing, selection of the ultrafiltration membrane 3, etc.) The dialysate storage bag 6 may be integrally connected to the arterial circuit 4 at the time of assembling, or may be connected to the arterial circuit 4 at the time of use. You may. The capacity of the dialysate storage bag 6 is 500-ml
(Milliliter) to 2-l (liter),
It can be set freely according to the purpose of treatment.
【０００６】次に体液処理装置１を用いた透析液のプラ
イミング方法の一例について説明する。最初に透析装置
１２より透析液を透析液導入チューブ８を経て、透析室
１４へプライミングする。続いて透析液出口１８及び血
液入口１５を封止するかあるいは透析液排出チュ−ブ９
及び動脈側回路４（血液入口１５の近く）の途中をクラ
ンプした後、透析液を限外ロ過膜３により逆ロ過して、
限外ロ過膜３を洗浄する。洗浄に使用した透析液は血液
出口１６、静脈側回路５を経て排出する。次に、血液出
口１６を封止するかあるいは静脈側回路５（血液出口１
６の近く）をクランプし、血液入口１５あるいは静脈側
回路４（血液入口１５の近く）を開放した後、透析液を
限外ロ過膜３により逆ロ過して、動脈側回路４、分岐チ
ューブ７を経て透析液貯留バッグ６に充填する。透析液
貯留バッグ６中の透析液を動脈側回路４を経て、血液室
１３、静脈側回路５にプライミングする。透析器２と各
回路４、５内に患者から導出した血液を返血する際にも
透析液貯留バッグ６中の透析液を透析器２と各回路４、
５中に流して使用することができる。Next, an example of a method for priming a dialysate using the body fluid treatment apparatus 1 will be described. First, the dialysate is primed from the dialyzer 12 into the dialysis chamber 14 via the dialysate introduction tube 8. Subsequently, the dialysate outlet 18 and the blood inlet 15 are sealed or the dialysate drain tube 9 is closed.
And after clamping the middle of the arterial circuit 4 (near the blood inlet 15), the dialysate is reverse filtered through the ultrafiltration membrane 3,
The ultrafiltration membrane 3 is washed. The dialysate used for washing is discharged through the blood outlet 16 and the venous circuit 5. Next, the blood outlet 16 is sealed or the vein side circuit 5 (the blood outlet 1) is closed.
6) and the blood inlet 15 or the venous circuit 4 (near the blood inlet 15) is opened, the dialysate is reverse filtered through the ultrafiltration membrane 3, and the arterial circuit 4 is branched. The dialysis fluid storage bag 6 is filled through the tube 7. The dialysate in the dialysate storage bag 6 passes through the arterial circuit 4 and is primed to the blood chamber 13 and the venous circuit 5. The dialysate in the dialysate storage bag 6 is also returned to the dialyser 2 and the respective circuits 4 and 5 when returning the blood derived from the patient to the dialyser 2 and the respective circuits 4 and 5.
5 and can be used.
【０００７】[0007]
【発明の作用効果】透析治療開始前に動脈側回路の途中
に設けた透析液貯留バッグ６内に透析液を限外ロ過３に
より逆ロ過して貯留しておくことができるので、これを
従来の生理食塩水の代わりにプライミングと返血時に使
用することができる。このため従来の様に多量の生理食
塩水を消費しなくても良いので安価な透析治療が可能と
なる。The dialysate can be stored in the dialysate storage bag 6 provided in the middle of the arterial circuit before the start of the dialysis treatment by reverse filtration through the ultrafiltration 3. Can be used during priming and blood return instead of conventional saline. For this reason, it is not necessary to consume a large amount of physiological saline as in the related art, so that inexpensive dialysis treatment can be performed.
【図１】本発明の体液処理装置の概略図。FIG. 1 is a schematic diagram of a body fluid treatment apparatus of the present invention.
１ 体液処理装置 ２ 透析器 ２ａ ハウジング ３ 限外ロ過膜 ４ 動脈側回路 ５ 静脈側回路 ６ 透析液貯留バッグ ７ 分岐チューブ ８ 透析液導入チューブ ９ 透析液排出チューブ １０、１１ チャンバー １２ 透析装置 １３ 血液室 １４ 透析液室 １５ 血液入口 １６ 血液出口 １７ 透析液入口 １８ 透析液出口 REFERENCE SIGNS LIST 1 body fluid treatment device 2 dialyzer 2a housing 3 ultrathin membrane 4 arterial circuit 5 venous circuit 6 dialysate storage bag 7 branch tube 8 dialysate introduction tube 9 dialysate discharge tube 10, 11 chamber 12 dialyser 13 blood Room 14 dialysate chamber 15 blood inlet 16 blood outlet 17 dialysate inlet 18 dialysate outlet
Claims (2)
（１３）と透析液室（１４）に区画し、前記血液室（１
３）の上流側に血液入口（１５）を形成するとともに下
流側に血液出口（１６）を形成し、前記透析液室（１
４）の上流側に透析液出口（１８）を形成するとともに
下流側に透析液入口（１７）を形成した、透析器（２）
と、 前記血液入口（１５）に接続される動脈側回路（４）
と、 前記血液出口（１６）に接続される静脈側回路（５）
と、 前記透析液入口（１７）に接続される透析液導入チュー
ブ（８）と、 前記透析液出口（１８）に接続される透析液排出チュー
ブ（９）とから構成され、 前記動脈側回路（４）の途中に分岐チューブ（７）を介
して前記限外ロ過膜（３）により逆ロ過された透析液の
貯留バッグ（６）を接続した、 ことを特徴とする体液処理装置（１）。1. An ultra-low membrane inside(3)Place the blood chamber
(13)And dialysate chamber(14)Partitioned into the blood chamber(1
3)Blood inlet upstream of(15)Form and below
Blood outlet on the downstream side(16)Forming the dialysisliquidRoom(1
4)Dialysate outlet upstream of(18)Together with
Dialysate inlet downstream(17)Formed dialyzer(2)
And the blood inlet(15)Arterial circuit connected to(4)
And the blood outlet(16)Vein side circuit connected to(5)
And the dialysate inlet(17)Dialysate introduction tube connected to
B(8)And the dialysate outlet(18)Dialysate drain tube connected to
B(9)WhenComposed of The arterial circuit(4)Branch tube in the middle of(7)Through
do itOf the dialysate reversely filtered by the ultrafiltration membrane (3)
Storage bag(6)Body fluid treatment device, characterized in that:(1).
項１記載の体液処理装置（１）のプライミング方法。
（１）：透析液導入チューブ（８）と透析液排出チュー
ブ（９）の端部を透析装置（１２）に接続し、透析液を
透析装置（１２）より、透析液導入チューブ（８）を経
て透析液室（１４）へプライミングする工程、 （２）：透析液を限外ロ過膜（３）により逆ロ過して、
限外ロ過膜（３）を洗浄する工程、 （３）：透析液を限外ロ過膜（３）により逆ロ過して動
脈側回路（４）、分岐チューブ（７）を経て透析液貯留
バッグ（６）に充填する工程、 （４）：透析液貯留バッグ（６）中の透析液を動脈側回
路（４）を経て血液室（１３）、静脈側回路（５）へプ
ライミングする工程、2. A priming method of the body fluid treatment device according to claim 1, characterized in that from each of the following steps (1).
(1): The ends of the dialysate inlet tube (8) and the dialysate outlet tube (9 ) are connected to a dialyzer (12) , and the dialysate is introduced from the dialyzer (12) into the dialysate inlet tube (8) . Priming into the dialysate chamber (14) via (2): reverse filtration of the dialysate through the ultrafiltration membrane (3) ,
A step of washing the ultrafiltration membrane (3) , (3): the dialysate is reversely filtered through the ultrafiltration membrane (3 ) and passed through the arterial circuit (4) and the branch tube ( 7). Filling the storage bag (6) , (4): priming the dialysate in the dialysate storage bag (6) via the arterial circuit (4) to the blood chamber (13) and the venous circuit (5) . ,
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32176194A JP3302520B2 (en) | 1994-11-30 | 1994-11-30 | Body fluid treatment device and priming method for body fluid treatment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32176194A JP3302520B2 (en) | 1994-11-30 | 1994-11-30 | Body fluid treatment device and priming method for body fluid treatment device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH08150201A JPH08150201A (en) | 1996-06-11 |
| JP3302520B2 true JP3302520B2 (en) | 2002-07-15 |
Family
ID=18136155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP32176194A Expired - Lifetime JP3302520B2 (en) | 1994-11-30 | 1994-11-30 | Body fluid treatment device and priming method for body fluid treatment device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3302520B2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3695506B2 (en) | 1998-10-07 | 2005-09-14 | ニプロ株式会社 | Dialysis machine and washing priming method |
| JP2000107283A (en) | 1998-10-07 | 2000-04-18 | Nissho Corp | Dialysis apparatus and washing priming method |
| ITBO20010354A1 (en) | 2001-06-05 | 2002-12-05 | Gambro Dasco Spa | METHOD OF FILLING AND WASHING OF A FILTER OF A DIALYSIS MACHINE |
| US8029454B2 (en) * | 2003-11-05 | 2011-10-04 | Baxter International Inc. | High convection home hemodialysis/hemofiltration and sorbent system |
| JP2011182992A (en) * | 2010-03-09 | 2011-09-22 | Kawasumi Lab Inc | Priming method and dialyzer of dialysis system |
| JP5573350B2 (en) * | 2010-05-17 | 2014-08-20 | ニプロ株式会社 | Blood purification equipment |
-
1994
- 1994-11-30 JP JP32176194A patent/JP3302520B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08150201A (en) | 1996-06-11 |
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