JP3132552U - Medical multi-chamber container - Google Patents

Abstract

Disclosed is a medical multi-chamber container capable of preventing administration of a drug before mixing to a patient.
An infusion bag main body, an easily peelable seal partition portion that partitions the infusion bag main body into a plurality of storage chambers, a discharge portion for discharging the liquid in the storage chamber, and an infusion bag main body. A sandwiching closure 10 having a suspension part provided for hanging the door and a pair of sandwiching pieces, and sandwiching both sides of the storage chamber by the pair of sandwiching pieces to block the suspension part unusable. The easily peelable seal partition portion 2 and the sandwiching closure 10 are sandwiched and closed so that the easily peelable seal partition portion 2 is opened and the hanging portion can be used as the internal pressure of the storage chamber 3 increases. The holding state of the tool 10 is released, and the easy-peeling seal partition portion 2 is composed of a first portion and a second portion having different peel strengths, and the second portion is the first portion. It has a peel strength that is easier to peel than the portion 2a.
[Selection] Figure 1

Description

  The present invention relates to a medical multi-chamber container having a plurality of storage chambers partitioned by an easily peelable seal partition.

  Among drugs administered to a patient by intravenous injection, there are unstable drugs that cause a change with time when pre-mixed. Examples of the change with time include so-called Maillard reaction that browns when an amino acid infusion and a glucose infusion are mixed and stored. In addition, if fat emulsion and electrolyte solution are blended and stored, the fat will aggregate, and if phosphoric acid-containing liquid and calcium-containing liquid are blended, calcium phosphate will precipitate and undesirable changes will occur. Wake up.

  The following medical multi-chamber containers are often used for such drugs. The medical multi-chamber container includes a plastic film container main body having two storage chambers for storing a drug, and a discharge unit for discharging the drug from the container main body. The two storage chambers are partitioned by an easily peelable seal partition portion in which the inner wall surfaces of the container body are heat-sealed. In use, the vicinity of the center of one of the storage chambers is pressed to increase the pressure in the storage chamber, and the easily peelable seal partition portion is opened. As a result, the two storage chambers communicate with each other and the two drugs are mixed. Thereafter, the discharge part is opened by insertion or the like, the container is suspended, and the mixed medicine is administered to the patient (for example, Japanese Patent Laid-Open No. 8-229099). In the above container, before opening the easy peel seal partition, that is, before mixing the drug, the discharge part is opened by insertion or the like, and a warning display is displayed so that the drug before mixing is not administered to the patient. Printed on the surface.

  However, it may be used without performing the mixing operation regardless of the alert display. In such a case, in the storage chamber on the side where the discharge part is attached, a solution that does not interfere with infusion alone is accommodated, but the medicinal solution to be mixed and used is not infused.

  Therefore, a medical multi-chamber container has been proposed in which infusion cannot be performed unless a mixing operation is performed (for example, International Publication No. WO2006 / 126459, Registered Utility Model No. 3118291).

  The present invention has improved a medical multi-chamber container in which infusion cannot be performed unless a mixing operation is performed, and a medical multi-chamber container that can more efficiently prevent administration of a drug before mixing to a patient. The issue is to provide.

  In order to solve the above problems, a medical multi-chamber container according to the present invention includes an infusion bag main body, an easily peelable seal partition that partitions the infusion bag main body into a plurality of storage chambers, and a liquid for discharging the liquid in the storage chamber. A discharge portion, a suspension portion used for hanging the infusion bag body, and a pair of sandwiching pieces, and sandwiching both surfaces of the storage chamber by the pair of sandwiching pieces, the discharge portion or the suspension portion A sandwiching closure that unusably closes the suspension part, and the easy-peeling seal partitioning part and the sandwiching closure are opened by the internal pressure rise of the storage chamber, and the discharge part Or it is comprised so that the clamping state of the said clamping device may be cancelled | released so that a hanging part can be used, The said easily peelable seal partition part is the 1st part and 2nd part from which peeling strength differs And the second part is the front The accommodation chamber on the side where the clamping device is not clamped is pressed to increase the internal pressure of the accommodation chamber, so that the first passage is opened prior to the first portion, and the throttle channel is formed by the opening that opens earlier. It has a peel strength that is easier to peel than the first portion.

  The clamping closure is sandwiched between the longitudinal ends of the medical multi-chamber container and the central portion in the lateral direction, and the easily peelable seal portion extends laterally between the longitudinal ends of the medical multi-chamber container. It is preferable that the second portion is provided at a central portion in the lateral direction of the easily peelable seal partition portion.

  It is preferable that the lateral length of the second portion is 1 to 2.5 times the lateral length of the clamping closure.

  It is preferable that the vertical width of the second portion is narrower than the vertical width of the first portion.

  The first portion includes a third portion and a fourth portion having different peel strengths, and the third portion is provided adjacent to the second portion, and moreover than the fourth portion. It is preferable to have peel strength that facilitates peeling.

  It is preferable that the third portion has a tapered portion whose width in the vertical direction is gradually reduced as it approaches the central portion in the horizontal direction.

  The opening strength of the easily peelable seal partitioning part is preferably 150 to 250N.

  In this specification, “vertical direction” means the vertical direction when the medical multi-chamber container is suspended, and “lateral direction” means the direction crossing the “vertical direction”. The same applies to the scope of the utility model registration request.

  According to the present invention, before the easy-release seal partition is opened, that is, before mixing the medicine, the hanging part cannot be used and the container cannot be suspended. Administration to a patient can be prevented.

    Hereinafter, an embodiment of a medical multi-chamber container according to the present invention will be described with reference to FIGS. In addition, the same code | symbol was attached | subjected about the same component through all the drawings and all embodiment.

  FIG. 1 is a perspective view showing an embodiment of a medical multi-chamber container according to the present invention, FIG. 2 shows a clamping closure attached to the medical multi-chamber container of FIG. 1, and (a) is a clamping state. (B) is a released state, (c) is a removed state corresponding to the II-II section of FIG. 3, respectively, FIG. 3 is a plan view of the medical multi-chamber container of FIG. 4 is a plan view showing the medical multi-chamber container with the clamping closure of FIG. 1 removed.

  The medical multi-chamber container includes an infusion bag main body 1 made of flexible and transparent plastic, and a plurality of storage chambers 3 and 4 formed by separating the infusion bag main body 1 by an easily peelable seal partition portion 2. And a discharge portion 5 for mixing and discharging the liquid in the storage chambers 3 and 4, and a hanging portion 6 for hanging the bag body 1 on the opposite side of the discharge portion 5 (see FIG. 4) ) Is formed, and the hanging part 6 is closed unusable by the sandwiching closure 10.

  In addition, when one or both of the storage chambers 3 and 4 are pressed, the infusion bag body 1 increases the internal pressure of the pressed storage chamber, and the easy peel seal partition portion 2 peels and stores in response to the increase in internal pressure. The chambers 3 and 4 are configured to communicate with each other.

  In the illustrated example, the hanging part 6 is formed by a through-hole penetrating the peripheral strong seal part 1a of the infusion bag body 1 as shown in FIG.

  The sandwiching closure 10 has a pair of first sandwiching pieces 11 a and second sandwiching pieces 11 b that can sandwich both sides of the storage chamber 4. The 1st clamping piece 11a and the 2nd clamping piece 11b are connected via the hinge part 14. As shown in FIG. The 1st clamping piece 11a and the 2nd clamping piece 11b are carrying out the substantially plate shape in the example of illustration.

  The first sandwiching piece 11 a is formed with a first cylindrical part 12 that can be fitted into the hanging part 6. The first cylindrical portion 12 has a locking protrusion 12 a formed on the outer peripheral surface. When the cylindrical portion 12 is fitted into the hanging portion 6, the locking protrusion 12 a becomes a strong peripheral edge seal portion 1 a of the infusion bag body 1. It is locked so that it cannot be pulled out immediately.

  A second cylindrical portion 15 that can be inserted into the first cylindrical portion 12 is formed in the second sandwiching piece 11b. The second cylindrical portion 15 is closed at the bottom so that it cannot penetrate through the inside of the cylinder.

  An engagement protrusion 13 a is formed on the inner peripheral surface of the first cylindrical portion 12, and an engagement protrusion 13 b that engages with the engagement protrusion 13 a is formed on the outer peripheral surface of the second cylindrical portion 15. The engagement protrusion 13 a is formed in a hook shape on the inner peripheral surface of the first cylindrical portion 12. The engaged protrusion 13b has a plurality of hook-shaped protrusions formed on the outer peripheral surface of the second cylindrical portion 15 at predetermined angular intervals.

  In a state in which the storage chamber 4 is sandwiched between the first sandwiching piece 11a and the second sandwiching piece 11b, the first sandwiching piece 11a and the second sandwiching member are engaged by engaging the engaging projection 13a and the engaged projection 13b. The clamping state with the piece 11b is maintained, and the through hole of the hanging part 6 is closed. In the sandwiched state, the first sandwiching piece 11a and the second sandwiching piece 11b are arranged so that the peripheral edges of the first sandwiching piece 11a and the second sandwiching piece 11b are connected to both sides of the storage chamber 4 and the peripheral strong seal portion 1a connected to the storage chamber 4. It is almost in close contact with no gaps, and cannot be opened with fingernails.

  The easy peel seal partition part 2 is formed by a seal part such as a substantially band-shaped heat seal that extends in the lateral direction of the infusion bag body 1, and is formed by a first part 2a and a second part 2b having different peel strengths. Has been. The second portion 2b is opened prior to the first portion 2a when the storage chamber 3 on the side where the sandwiching closure 10 is not sandwiched is pressed and the internal pressure of the storage chamber 3 is increased. The peel strength is easier to peel than the first portion 2a. Since the second portion 2b opens prior to the first portion 2a, the opening formed by the second portion 2b forms a throttle channel temporarily or instantaneously.

  In the illustrated example, the through-hole constituting the hanging part 6 is formed at one end in the vertical direction of the medical multi-chamber container and at the center in the horizontal direction, and is sandwiched so as to cover the hanging part 6. The closing tool 10 holds the storage chamber 4 from both sides, and the second portion 2b is provided at a position facing the holding closing tool 10, that is, at the center in the horizontal direction of the easy-release seal partition portion 2. ing.

  In order to make the second portion 2b easier to peel from the first portion 2a, the vertical width D2 of the second portion 2b is narrower than the vertical width D1 of the first portion 2a. Further, the lateral length W1 of the second portion 2b is 1 to 2.5 times the lateral length W2 of the sandwiching closure 10.

  Further, the opening strength of the easily peelable seal partition portion 2 is 150 to 250 N, preferably 180 to 230 N. Here, the “opening strength” means the strength to withstand that all of the easy-peeling seal portion 2 peels (that is, opens). On the other hand, the peel strength means the strength with which a predetermined range portion of the easy peel seal portion 2 can withstand the peel.

  In the present invention, the opening strength is a flat plate of 90 x 90 mm, a flat plate is installed on the container 3 of the infusion bag 1 placed on a flat surface, and a pressing force is applied from the outside. Then, the opening strength when the easily peelable seal portion 2 was opened was measured at a pressing speed of 200 mm / min and a pressing load of 1000 N using an autorough (compression tester manufactured by Shimadzu System Solutions Co., Ltd.). For the peel strength, prepare a film piece with an easy peel seal part with a length of 70 mm and a width of 15 mm, and measure the peel strength per predetermined length by pulling an autograph (Shimadzu System Solutions Co., Ltd. tensile tester). It was measured at a pulling speed of 200 mm / min and a pulling load of 100 N.

  Usually, the opening strength of the easily peelable seal partition portion in this type of container is 300 to 2000 N (see JP 2004-476 A). This is for the purpose of preventing the easily peelable seal partitioning portion from being opened before use due to an impact during transportation or the like, but it is difficult for medical personnel with weak power to open. Therefore, in the case of using the clamping device as in the present invention, the flow rate from the storage chamber 3 to 4 is slow and the pressure in the storage chamber 4 increases slowly, so that the clamping device is not released. There was a problem. Therefore, by setting the opening strength of the easy peel seal partition portion 2 to 150 to 250 N, the easy peel seal partition portion 2 can be opened and the sandwiching closure 10 can be released with certainty.

  Further, since this type of container is transported by folding the easy peel seal partition 2 like a hinge, the impact is likely to be applied to the end of the easy peel seal partition 2, that is, the first portion 2 a. Therefore, this type of problem can be prevented by making the seal width (longitudinal width) of the first portion 2a thicker than that of the second portion 2b or by increasing the peel strength. In this case, the peeling strength per predetermined length of the first portion 2a is 2 to 5 N / 15 mm, preferably 2.3 to 4 N / 15 mm, and the peeling per predetermined length of the second portion 2 b. The strength is 2 to 3 N / 15 mm, preferably 2.3 to 2.7 N / 15 mm. The seal width (vertical width) of the first portion 2a is preferably 1.1 to 1.2 times that of the second portion 2b. If it is less than 1.1 times, the above effect cannot be obtained sufficiently, and if it is more than 1.2 times, the appearance of the container may be impaired.

  In the medical multi-chamber container having the above-described configuration, the easy-release seal partition portion 2 is firstly pressed by manually pressing the storage chamber 3 to which the holding closure 10 is not attached to increase the internal pressure of the storage chamber 3. Is opened. At this time, the second portion 2b is opened prior to the first portion 2a, and a temporary or instantaneous throttle channel is posted by the opening of the second portion 2b.

  Since the first clamping piece 11a and the second clamping piece 11b of the clamping closure 10 clamp the storage chamber 4, the first clamping piece 11a and the second clamping piece 11b are separated as the internal pressure of the storage chamber 4 increases. Force acts in the direction of With the action of this force, the engagement state between the engagement protrusion 13a and the engagement protrusion 13b is released, and the holding state between the first holding piece 11a and the second holding piece 11b is also released (FIG. 2B). )).

  By forming the throttle channel as described above, the force of the pressed liquid in the storage chamber 3 flowing to the adjacent storage chamber 4 increases, and the sandwiched state of the sandwiching closure 10 is easily released. That is, the flow rate from the storage chamber 3 to the storage chamber 4 is increased by the throttle channel compared with the case where the first portion 2a and the second portion 2b are simultaneously opened, and the holding closure 10 The pressure in the storage chamber 4 for pushing open the first clamping piece 11a and the second clamping piece 11b is also increased. In addition, since the second portion 2b is arranged at a position facing the sandwiching closure 10, the liquid whose flow rate is increased by the throttle channel flows directly toward the sandwiching closure 10, This makes it easier to release the holding of the holding closure 10. Further, by setting the lateral length W1 of the second portion 2b to 1 to 2.5 times the lateral length W2 of the sandwiching closure 10, the pressure flow flowing directly to the sandwiching closure 10 is sandwiched and closed. The release of the clamping closure 10 can be promoted by hitting substantially the entire tool 10. Immediately after the second portion 2b is opened, the first portion 2a is opened.

  When the engagement between the first sandwiching piece 11a and the second sandwiching piece 11b is released and the sandwiching state is released, the sandwiching closure 10 is removed from the medical multi-chamber container 1 (FIG. 2 (c)), and the sandwiching closure is performed. Since the hanging part 6 that has been closed by the first holding piece 11a and the second holding piece 11b of the tool 10 appears and can be used and the medical multi-chamber container 1 can be suspended, the medicine discharge port 5 Can be opened by needle insertion or the like, and the mixed drug can be introduced into the patient.

  As mentioned above, although embodiment of this invention was described, this invention is not limited to the said embodiment, A various change is possible unless it deviates from the meaning of this invention.

  For example, as shown in FIG. 5, the first portion 2a is composed of a third portion 2aa and a fourth portion 2ab having different peel strengths, and the third portion 2aa is adjacent to the second portion 2b. The third portion 2aa is provided with a tapered portion 2t having a longitudinal width D1 that gradually decreases as it approaches the central portion in the horizontal direction, and has a peel strength that is easier to peel than the fourth portion 2ab. Can be made.

  The taper portion 2t has an effect of guiding the liquid flow in the storage chamber 3 to the second portion 2b during the opening operation described above, and collects the liquid flow in the throttle channel formed by the second portion 2b. The liquid inside is vigorously flowed into the storage chamber 4.

  In the example shown in FIG. 5, the first portion 2 a protrudes toward the storage chamber 3. However, as shown in FIG. 6, the first portion 2 a protrudes to both sides of the storage chambers 3 and 4. Anyway.

  Furthermore, in said embodiment, in order to form the 1st part 2a and the 2nd part 2b in the easily peelable seal partition part 2, it formed by changing the vertical direction width | variety of the easily peelable seal partition part 2. Make a difference in the peel strength by forming a step on the heating contact surface of a heating iron (not shown) used for heat sealing and making a difference in the pressing force of the heating iron during heat welding. You can also. In this case, the peel strength per predetermined length of the first portion 2a is 2 to 5 N / 15 mm, preferably 2.3 to 4 N / 15 mm, and the peel strength per predetermined length of the second portion 2 b is 1.5 to 3 N / 15 mm, preferably 1.8 to 2.7 N / 15 mm. FIG. 7 is an example showing a medical multi-chamber container provided with an easily peelable seal partition portion 2 formed as described above, FIG. 7 (a) is a plan view, and FIG. 7 (b) is FIG. 7 (a). It is bb sectional drawing of).

  Further, the sandwiching closure for covering the hanging part 6 is not limited to the above-described embodiment, but the sandwiching closure disclosed in the registered utility model No. 3118291 and various other forms can be adopted. . Further, in the above-described embodiment, only the sandwiching closure for covering the hanging part 6 has been described. However, instead of the sandwiching closure for covering the hanging part 6, it is disclosed in International Publication No. WO2006 / 126459. The present invention can also be applied to a medical multi-chamber container equipped with a closing closure that closes the discharge portion, such as a holding closure that closes the discharge portion.

It is a perspective view which shows one Embodiment of the medical multi-chamber container which concerns on this invention. FIG. 1 shows a holding closure attached to the medical multi-chamber container of FIG. 1, wherein (a) shows a holding state, (b) shows a released state, and (c) shows a removed state, respectively, in the section II-II in FIG. It is center sectional drawing shown correspondingly. It is a top view of the medical multiple-chamber container of FIG. It is a top view which shows the medical multiple-chamber container which removed the clamping closure of FIG. It is a top view which shows the change aspect of the medical multiple chamber container which concerns on this invention. It is a top view which shows the change aspect of the medical multiple chamber container which concerns on this invention. FIG. 7 (a) is a plan view and FIG. 7 (b) is a cross-sectional view taken along line bb of FIG. 7 (a), showing a modification of the medical multi-chamber container according to the present invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Medical multiple-chamber container 2 Easy peel seal partition part 2a 1st part 2b 2nd part 2aa 3rd part 2ab 4th part 3 and 4 Storage chamber 6 Hanging part 10 Clamping closure 11a, 11b Clamping piece

Claims (7)

An infusion bag body,
An easily peelable seal partition that partitions the infusion bag body into a plurality of storage chambers;
A discharge part for discharging the liquid in the storage chamber;
A hanging part provided for hanging the infusion bag body,
A pair of sandwiching pieces, and a sandwiching closure that sandwiches both sides of the storage chamber by the pair of sandwiching pieces and unplugs the discharge part or the hanging part unusably.
The easily peelable seal partition portion and the sandwiching closure of the sandwiching closure device are configured so that the easily peelable seal partition portion is opened and the discharge portion or the hanging portion can be used due to an increase in internal pressure of the storage chamber. It is configured to release the pinching state,
The easy peel seal partition part is composed of a first part and a second part having different peel strengths,
The second portion is opened before the first portion due to an increase in the internal pressure of the storage chamber when the storage chamber on the side where the clamping device is not sandwiched is pressed, and an opening that opens ahead of the first portion. A medical multi-chamber container having a peel strength that is more easily peeled from the first portion so as to form a throttle channel. The clamping closure is sandwiched between the longitudinal ends of the medical multi-chamber container and the central portion in the lateral direction, and the easily peelable seal portion extends laterally between the longitudinal ends of the medical multi-chamber container. 2. The medical multi-chamber container according to claim 1, wherein the second portion is provided at a central portion in a lateral direction of the easy-peel seal partition portion. The medical multi-chamber container according to claim 2, wherein a lateral length of the second portion is 1 to 2.5 times a lateral length of the sandwiching closure. The medical multi-chamber container according to claim 1, wherein the vertical width of the second portion is narrower than the vertical width of the first portion. The first portion is composed of a third portion and a fourth portion having different peel strengths,
2. The medical multi-chamber container according to claim 1, wherein the third portion is provided adjacent to the second portion and has a peel strength that is easier to peel than the fourth portion. 6. The medical multi-chamber container according to claim 5, wherein the third portion has a tapered portion whose width in the vertical direction is gradually narrowed toward the lateral center. The multi-chamber container for medical use according to any one of claims 1 to 6, wherein an opening strength of the easily peelable seal partition portion is 150 to 250N.

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