JP3051021U - Health promotion agent by combination of Bifidobacterium and certain oligosaccharides - Google Patents

Abstract

(57) [Summary] (Corrected) [Solving Means] A health promoting agent in which a bifidobacterium wrapped in enteric-coated soft capsules and a certain type of oligosaccharide formed by tableting are enclosed in a bag of packaging material. [Effect] By wrapping only bifidobacteria and certain oligosaccharides in a single bag and ingesting them together, the balance of intestinal bacteria due to the relationship between bifidobacteria and food (oligosaccharides) is maintained, and human health is maintained and Can be improved.

Description

[Detailed description of the invention]

[0001]

[Technical field to which the invention belongs]

 The present invention relates to the combination of bifidobacteria with certain oligosaccharides that have been eaten by humans for a long time, such as onions, burdock, bananas, honey, bamboo shoots, soybeans, sweet potatoes, starch, and milk. There is strangely. In order to get the weak bifidobacteria to the intestine, it is necessary to gently wrap them in enteric-coated soft capsules. In order to grow weak bifidobacteria that finally arrived in the intestine in a harsh environment where harmful bacteria in the intestine (such as Escherichia coli and Welsh bacteria) are proliferating, certain oligosaccharides are put together. It is important to take. Certain oligosaccharides can only feed on bifidobacteria, not on harmful bacteria (such as Escherichia coli and Welsh bacteria). Ingesting oligosaccharides as a diet for Bifidobacteria enables them to live in harsh intestinal environments. By wrapping only bifidobacteria and certain types of oligosaccharides in a single bag and ingesting them together, it is possible to maintain the balance of intestinal bacteria due to the relationship between bifidobacteria and diet (oligosaccharides) and maintain and promote human health. And for the purpose.

[0002]

[Prior art]

 Currently, bifidobacteria and certain oligosaccharides are found in various foods and drinking waters. It is commercialized in cookies, wafers, chocolate, candy, chewing gum, yogurt, lactic acid bacteria drinks, ice cream, and anything else. However, the relationship between bifidobacteria and oligosaccharides in all products does not seem to be understood by consumers. Bifidobacterium is a very weak microorganism and cannot reach the intestine by oral administration. It is necessary to devise ways to process weak bifidobacteria and reach the intestines. Even if it does, it is not easy to create a condition where bifidobacteria become dominant in the intestine if severe and strong harmful bacteria (such as Escherichia coli and Welsh bacteria) occupy the intestine. As a form of food material, a method such as `` Bifidobacterium powder '', `` oil-coated bifidobacterium powder '', or `` Bifidobacterium microcapsule '' has been devised so that weak bifidobacteria can be produced and reach the intestine. We are. Bifidobacteria and oligosaccharides are used in all kinds of food and drinking water, but none has been commercialized using only bifidobacteria and oligosaccharides.

[0003]

[Problems to be solved by the invention]

 Sugar is an excellent sweetener, but it is a problem as a cause of tooth decay, obesity or diabetes. Sugar is broken down and absorbed in the small intestine and used as energy for the human body. However, some oligosaccharides do not break down in the small intestine and are not absorbed. So it is not used for human energy. An example of a method for producing certain types of oligosaccharides is as follows: When an enzyme that degrades sugar that black mold produces is used and high-concentration sugar is used as a raw material to act at high temperatures, fructose produced while decomposing sugar Is linked to the end of the sugar to form a type of oligosaccharide. This oligosaccharide is a health-oriented material with high quality and refreshing sweetness similar to sugar. This type of oligosaccharide reaches the intestine without being digested in the human stomach. It is characterized by its ability to feed on intestinal bacteria, especially lactic acid bacteria (Bifidobacteria), and not on harmful bacteria (such as Escherichia coli and Welsh bacteria). Therefore, it is used as a feed for lactic acid bacteria (Bifidobacterium) in the intestine, can promote the growth, and can suppress the growth of harmful bacteria (such as Escherichia coli and Welsh bacteria). The growth of bifidobacteria in the intestine and a better balance of the intestinal environment help maintain health. Getting through the harsh stomach and getting to the intestines is no easy task. Vulnerable bifidobacteria almost die from the mouth, through the esophagus, to the stomach, and do not reach the intestine. The weak bifidobacteria must be gently wrapped in an enteric-coated soft capsule to reach the intestine, and the weak bifidobacterium that has finally reached the intestine can be transformed into harmful bacteria in the intestine (Escherichia coli and Welsh bacteria). Ingest certain sugars together so that they can grow and survive in the harsh environment in which they grow. Certain oligosaccharides can only feed on bifidobacteria and not on harmful bacteria (such as Escherichia coli or Welsh bacteria), so they can start to live in harsh intestinal environments. Bifidobacterium is covered with gelatin, and gently wrapped in enteric-coated soft capsule. It is important to make enteric-coated soft capsules with a film component that allows living bifidobacteria to reach the intestine.It is important that certain types of oligosaccharides formed by tableting reach the intestine at the same time as food for bifidobacteria. This is the biggest issue.

[0004]

[Means for Solving the Problems]

 Enteric-coated capsules are designed to dissolve Bifidobacteria in the stomach without reaching the intestine and then dissolving them, and then absorb the components in the intestine. In the past, enteric capsule capsule components that could not be produced without the use of pharmaceutical ingredients were realized with natural food ingredients zein and sodium alginate. Zein is a natural protein found in corn. Sodium alginate is a natural dietary fiber found in kelp and seaweed. The use of this enteric capsule film eliminates the blocking property of the capsule and significantly improves heat resistance and strength compared to conventional soft capsules. By using this enteric capsule membrane, living bifidobacteria mixed with gelatin can be wrapped softly and can reach the intestine. The shape and content can be freely set to build up. Certain orico sugars are available in granules, powders, and liquids. Bifidobacteria mixed with gelatin wrapped in a capsule of enteric-coated capsules and certain oligosaccharides are included together, so tablets or granules are used to form tablets. The packaging material that wraps the bifidobacteria and the orico-sugar together uses a transparent two-layer film. The outside is a transparent film of polyethylene terephthalate and the inside is silica-deposited with polyethylene. A three-way heat seal is made of a transparent two-layer film only, while a four-way heat seal uses an aluminum-deposited film.

[0005]

[Embodiment of the invention]

 Bifidobacteria wrapped in an enteric-coated capsule and certain types of oligosaccharides formed by compression can maintain the raw material as natural and natural as possible and maintain its freshness. In the process of chemical conversion, consideration must be given to product forms that have little quality deterioration factors such as additives, heat, water, pressure, and air oxidation. Other factors such as daily intake, absorption into the body, ease of eating, ease of handling, cost, and relevant laws and regulations must also be considered. The reason that this product form was clearly limited to tableted products and soft capsules, rather than food forms, is largely because these forms are superior in maintaining the stability of specific ingredients.

[0006]

【Example】

 (2) One bifidobacterium wrapped in a film of enteric-coated capsules and three types of oligosaccharides formed by tableting in appropriate quantities. Wrap the aluminum-deposited two-layer film in a bag of appropriate size and shape (three-way heat seal, four-way heat seal). (2) A bag containing an appropriate amount of 1 type of bifidobacterium wrapped in a capsule of enteric coated capsule and 3 types of oligosaccharides formed by tableting, and making a box that contains the appropriate amount of the bag and properly fits in it I'm sorry.

[0007]

[Effect of the invention]

 Examining the status of this type of oligosaccharide in the gastrointestinal tract, it is said that there are hundreds of bacteria inhabiting the human intestine, and that there are one hundred trillion. About 10% of the dry weight of stool is bacterial cells. Most of the intestinal bacteria in newborn infants are bifidobacteria, but the number of bacteria such as Escherichia coli and Welsh is increasing over time. In older people, Escherichia coli and Welsh bacteria dominate intestinal bacteria. Bifidobacteria and lactic acid bacteria are useful bacteria for humans, and in particular, bifidobacteria have a function of suppressing harmful bacteria in the large intestine. Typical physiological effects of bifidobacteria include intestinal action, improvement of intestinal flora, suppression of intestinal putrefaction products, improvement of defecation properties, immunostimulatory effect, enhancement of bone strength, and synthesis of vitamins. Certain oligosaccharides have the characteristic of improving the intestinal microflora by allowing individual individuals to grow the bifidobacteria in the intestine more specifically by suppressing other bacteria. In other words, when used as a feed for bifidobacteria, it has the same physiological function as bifidobacteria and contributes to maintaining and promoting our health.

[Brief description of the drawings]

FIG. 1. Bifidobacterium mixed with gelatin wrapped in enteric capsules.

FIG. 2. Certain types of oligosaccharides formed by compression.

FIG. 3 is a bag made of a transparent two-layer film enclosing bifidobacteria wrapped in an enteric capsule and certain oligosaccharides formed by tableting. (A) Three-way heat sealing. (B) Four-way heat sealing.

FIG. 4 is a form commercialized by three-way heat sealing.

[Explanation of symbols]

 1. Bifidobacterium mixed with gelatin. 2. Capsule coating. 3. Certain oligosaccharides. 4. polyethylene terephthalate. 5. polyethylene. 6. Aluminum foil. 7. Heat seal part.

Claims (1)

[Utility model registration claims] 1. A health promoting agent comprising bifidobacteria wrapped in an enteric soft capsule and a certain type of oligosaccharide formed by tableting enclosed in a bag of packaging material.