JP3046991U - Disposable component detector for test solution analyzer - Google Patents

Abstract

(57) [Summary] (Modifications required) [Problem] The number of parts is small, the structure is simple, the test solution can be easily and safely injected, and the contact between the test solution and the atmosphere can be avoided as much as possible. Provided is a disposable component detector for a test solution analyzer capable of obtaining a proper test value. A test solution passage is provided inside a housing, and a test solution injection hole is provided in an upstream portion of the test solution passage.
The exhaust device 104 is provided in the downstream portion, and a sensor device 103 capable of detecting at least one component of the test liquid injected into the test liquid passage 101 is provided. The terminal is provided so as to be exposed at a portion between the air outlet 102 and the exhaust hole 104 and the terminal portion thereof is exposed to the outside of the housing 100. A plug member 105 made of a permeable material is provided.

Description

[Detailed description of the invention]

[0001]

[Technical field to which the invention belongs]

 The present invention provides an improved device for detecting components in a test solution that can be used in a test solution analyzer that can measure and analyze gas components, pH values, etc. in test solutions such as body fluids of humans and animals. About.

[0002]

[Prior art]

 This type of test solution analyzer is used for examining the cardiopulmonary function of a patient, for example, inside a facility such as a hospital or an analysis center, or outdoors such as at an accident site, etc. Pressure PO2, sodium Na, potassium K, chlorine Cl, calcium ion Ca, urea nitrogen BUN, glucose Glu, hematocrit Hct, bicarbonate ion HCO3-, oxygen saturation SO2, total carbon dioxide TCO2, excess base BE, It is used for measuring and analyzing the concentration of various gases and ions such as hemoglobin Hgb, and various stationary and portable types have been proposed and put to practical use. Particularly, as a portable analyzer, for example, Japanese Patent Publication No. 8-20398 discloses a component detector equipped with a sensor device having a plurality of detectors for detecting components in a test solution separately from the main body of the analyzer. An analyzer of the type provided is disclosed. The above-described component detector includes: a holding portion for holding a liquid sample to be analyzed in the housing (hereinafter, referred to as a test solution), a test solution passage communicating with the holding portion, and a test solution passage. A storage device provided downstream of the test liquid passage, and an air storage portion that contains a predetermined amount of air therein and has a portion that can be deformed by an external pressing force. An air pressure supply passage communicating the air storage unit and the holding unit is provided, and is configured to be detachable from the test liquid analyzer main body. The component detector configured as described above is configured to be detachable from a dedicated analyzer, and when an operator drops a test liquid to be analyzed onto the holding unit, and then attaches the component detector to the analyzer, the analysis is performed. Pressing means provided on the apparatus side presses the air storage section to push out the air in the air storage section to the holding section side, and the test liquid held in the holding section flows to the test liquid passage by the air pressure, and the sensor It is configured to be in contact with the detection unit of the device. As described above, in the conventional component detector for a portable analyzer, the test solution is temporarily held in the holding unit, and is pushed out of the air storage unit by being mechanically pressed by the analyzer. Since the test liquid is flushed to the detection part of the sensor device with air, the amount of air that pushes out the test liquid can always be kept constant, and a predetermined amount of test liquid is accurately held in the holding part. This has the effect that the test liquid can be reliably supplied to the detection unit of the sensor device. In addition, since the amount of air pushed out from the air storage unit, the distance between the test solution passage and the detection unit of the sensor device, and the volume of the test solution holding unit are fixed, the necessary amount of the test solution is minimized. It is also possible to perform analysis with a small amount of test solution.

[0003]

[Problems to be solved by the invention]

 However, the above-described conventional component detector for a portable analyzer can reduce the required amount of test solution and downsize the component detector itself, but the amount of air supplied to the test solution holding unit is constant. As a result, the amount of test liquid to be held in the holding section must be kept constant, and the amount is very small. As a result, analysis is performed in a very small test liquid holding section. There is a problem in that the operator has to perform a difficult task of dropping the required amount of the test liquid accurately. In particular, portable test solution analyzers that use such a component detector are more suitable for use outdoors, such as at accident sites and ambulances, as well as on moving vehicles, rather than in hospitals or analysis centers. This is a problem because the fine work of accurately dropping a small amount of the test liquid to the holding portion of the component detection tool as described above is a great burden for the operator. In addition, if the test solution holding part is small, the test solution cannot be dripped into the holding part well and the test solution leaks out to the housing surface. There is a danger of touching the liquid directly. Furthermore, if the test liquid is dropped as described above, the test liquid comes into contact with the atmosphere when the test liquid is dropped, the components to be measured in the test liquid are affected, and accurate measurement can be performed. There is also the problem that it may disappear. Furthermore, the above-described conventional component detection device must be provided with a deformable air storage unit or a mechanism for pressing the air storage unit on the analyzer side. Not only is this complicated, but also the configuration of the analyzer becomes complicated.

Accordingly, the present invention solves the various problems associated with such a conventional disposable component detector for a test solution analyzer, and has a simple structure with a small number of parts and a simple test solution. It is an object of the present invention to provide a disposable component detector for a test solution analyzer that can be injected safely, can minimize contact between the test solution and the atmosphere, and can obtain an accurate test value.

[0005]

[Means for Solving the Problems]

 In order to achieve the above object, a disposable component detector for a test solution analyzer according to the present invention includes a test solution passage inside a housing, and a test solution injection hole provided in an upstream portion of the test solution passage. An exhaust hole is provided in the downstream portion, and a sensor device capable of detecting at least one component of the test liquid injected into the test liquid passage is provided between the injection hole and the exhaust hole in the test liquid passage. And a terminal portion thereof is exposed to the outside of the housing, and a plug member made of a material permeable to air and impermeable to liquid is provided in the exhaust hole. Wherein the terminal portion is configured to be detachably connected to an analyzer capable of analyzing at least one component in the test solution based on the detection result of the detection portion. .

[0006]

DESCRIPTION OF THE PREFERRED EMBODIMENTS FIG. 1 is a schematic top view and an AA cross-sectional view of a disposable component detector (hereinafter simply referred to as a detector) for a test solution analyzer showing one embodiment of the present invention. It is. As shown in FIG. 1A, the detector has a test liquid passage 101 inside a housing 100, a test liquid injection hole 102 at an upstream end of the test liquid passage 101, and a test liquid passage 102 at a downstream end. Exhaust holes 103 are respectively formed. A sensor device 104 for detecting a component to be analyzed in the test liquid is provided in the test liquid passage 101. Although not shown in detail, the sensor device 104 is arranged so that its detecting portion is exposed inside the test solution passage 101, and its terminal portion is exposed outside the housing 100. It is arranged so that a terminal part can be attached to an analyzer (not shown). Further, as shown in FIG. 1B, a plug member 105 formed to have a property of being permeable to air and impermeable to liquid is attached to the exhaust hole 103. The plug member 105 is made of, for example, a porous synthetic resin made of a water-repellent material in which pores contain a water-absorbing resin having a high water absorption. To briefly explain the operation of the component detector configured as described above, the component detector is first set in an appropriate analyzer so that the injection hole 102 is exposed to the outside. At this time, the terminal of the sensor device 104 is connected to the detection result input terminal of the analyzer. When the operator inserts the nozzle portion 106a of the test liquid injector 106 into the injection hole 102 and injects a test liquid such as blood from the injection hole 102 with the test liquid injector 106, the test liquid is injected into the plug member 105. At this point, the water-absorbent resin absorbs the test liquid and swells to close the pores of the porous synthetic resin, so that the plug member 105 seals the exhaust hole 103 and the test liquid is further injected with the injector 106. Prevent infusion. This ensures that the inside of the test liquid passage 101 is filled with the test liquid from the injection hole 102 to the exhaust hole 103, and the detection liquid of the sensor device 104 provided between the injection hole 102 and the exhaust hole 103 is supplied to the detection liquid. Is reliably supplied. When the detection unit of the sensor device 104 touches the test liquid, it reacts with a predetermined component, and the result appears as a current value or a voltage value at the terminal unit. The analyzer measures and analyzes each component based on the current and voltage values obtained from these terminals, and displays them on an appropriate monitor or prints them out. As described above, when injecting the test solution, the operator simply attaches the nozzle of the injector to the injection hole and injects the test solution with the injector until it can no longer be injected. The operator does not need to pay attention to the injection volume, etc., since the required amount of test solution can be reliably injected. The test liquid passage 101 may have various forms. For example, a waste liquid portion having a volume capable of storing a predetermined amount of test liquid is provided downstream of the sensor device 104, and the waste liquid portion is provided. An exhaust hole may be provided in the downstream part of the air conditioner. By providing the waste liquid portion in this way, it becomes possible to increase the amount of the test liquid that can be injected or to flow a calibration liquid described later. In addition, the length of the test liquid passage 101 can be appropriately set according to the number of detection units of the sensor device and the amount of the test liquid to be injected. Further, the injection hole 102 is preferably formed so that the nozzle portion 106a of the injector 106 can be fitted in a liquid-tight manner. For example, the nozzle portion 106a of the injector may be adapted to the size and shape of the nozzle portion of the syringe according to JIS standards. The portion may be tapered so that it can be fitted in a liquid-tight manner, and a sealing member may be provided on the injection hole 102 and / or the nozzle portion 106a of the injector. Further, the detection tool communicates with a storage portion for storing a calibration liquid for performing calibration on each detection portion of the sensor device as necessary, and an upstream portion of the sensor device in the test liquid passage 101 from the storage portion. A communication path may be provided so that the calibration liquid flows through the sensor device before the test liquid is injected, so that calibration of each detection unit can be performed.

[0007]

【Example】

 Next, a more specific embodiment of the detector according to the present invention will be described with reference to one embodiment shown in FIGS. FIG. 2 is a schematic development view of the detection tool according to the present invention, and FIG. 3 is a schematic top view of a test liquid passage in the detection tool after the housing is assembled, which will be described later. As shown in the figures, the detector comprises a housing 1 made of a suitable material such as a transparent or translucent plastic. The housing 1 is composed of two substrates 1A and 1B which are superimposed on each other and a thin partition plate 1C having an adhesive layer on both sides. The partition plate 1C is sandwiched between the two substrates 1A and 1B. Is assembled so that the two substrates 1A and 1B are joined in a liquid-tight manner.

On one substrate 1A, on the inner surface, that is, the surface facing the thin partition plate 1C, a test solution passage 2 formed by a groove for passing a test solution such as a body fluid of a human or animal to be tested is formed. It is formed in a U-shape along the peripheral edge. At the upstream end of the test liquid passage 2, an injection hole 3 for the test liquid communicating with the outside of the housing is formed, and at the downstream portion of the test liquid passage 2, a first waste liquid formed in a zigzag shape is formed. The part 4 is formed. FIG. 4 is a partial cross-sectional view of a portion corresponding to the injection hole 3 in the base 1A. As shown in the drawing, the injection hole 3 is slightly tapered from the inner surface to the outer surface of the substrate 1A. A guide shoulder 3a is provided around the injection hole 3 on the outer surface of the body. As a result, a test liquid injector (not shown) such as a syringe can be hermetically inserted into the injection hole 3, and the test liquid can be injected into the test liquid passage 2 without touching the atmosphere.

The grooves constituting the first waste liquid portion 4 are formed in a zigzag as shown in FIGS. 2 and 3, and the width and depth thereof are different from those of the test liquid passage 2 to obtain a sufficient volume. It is set larger than the part. As shown in FIGS. 2 and 3, the test solution passage 2 has a relatively narrow portion 2a extending from the injection hole 3, a detecting portion contact portion 2b following the relatively narrow portion 2a, and a detecting portion. It has a constricted portion 2c following the part contact portion 2b, and a portion 2d extending from the constricted portion 2c to the first waste liquid portion 4. On the upstream side of the sensor contact portion 2b of the test liquid passage 2, a narrow groove 6 forming a part of the calibration liquid passage is formed inward. Further, a branch passage 7 extending toward the peripheral edge portion is formed in the sensor contact portion 3b of the test liquid passage 3, and the leading end of the branch passage 7 terminates in a through hole 8. The through hole 8 is positioned so as to be opposed to the reference electrode, and can be loaded with a gel-like saturated potassium chloride solution. Further, an opening 9 is formed in an inner region of the one substrate 1A surrounded by the U-shaped test liquid passage 2, and this opening 9 is a means for pressing a calibration liquid container described later at the time of measurement. It is provided to receive. Furthermore, a through hole 10 for guiding and locking when a detection tool is inserted into a test liquid analyzer described later is provided at a substantially central portion of one substrate 1A.

On the other side of the substrate 1B, a shallow concave surface 12 for mounting the sensor device 11 is formed along one corner on the inner surface thereof, that is, the surface facing the thin partition plate 1C. At the position corresponding to the opening 9 in the substrate 1A, the mounting concave surface 14 of the calibration liquid container 13 is formed. FIG. 5 is an enlarged view of a portion corresponding to the mounting concave surface 14 of the calibration liquid container 13 and the substrate 1B. As shown in the drawing, the calibration liquid container 13 is made of a material having no gas permeability or a low material. Inside, a reagent for calibration of each detection unit in the sensor device 11 is hermetically accommodated. In this embodiment, the outer periphery 13a of the calibration liquid container is bonded at least so as not to be peeled off by the internal pressure when pressed by the pressing means of the analyzer described later. A discharge portion 13b is formed on the outer peripheral edge portion 13a, and a portion corresponding to the discharge portion 13b is formed of an easily peelable sealant so as to be peelable at least under an internal pressure when pressed by a pressing means of an analyzer described later. Glued. The peeling mechanism using the easily peelable sealant includes an interfacial peeling mechanism in which the sealant and the adherend are not completely fused and can be peeled with an appropriate strength, and can be peeled between the coating layer and the laminate film. A delamination mechanism or an agglomeration delamination mechanism that peels off due to internal cohesion and destruction of the sealant layer upon opening can be considered. By forming the calibration liquid container as described above, only the release section 13b is peeled off when pressed by the pressing means of the analyzer described later, so that the internal reagent can be released from the calibration liquid container. Become. In this way, the strength of the calibration liquid container is reduced compared to a detector that uses a structure in which the calibration liquid container is broken with a needle-shaped object to release the calibration liquid by forming the discharge part using the easily peelable sealant. As a whole, it can be made higher, and as a result, a material having low gas permeability can be used, so that the storage stability of the reagent when storing the detector is remarkably improved. In addition, a position corresponding to the free end of the narrow groove 6 which constitutes a part of the calibration liquid passage on one substrate 1A from the portion corresponding to the discharge portion 13b of the calibration liquid container 13 of the mounting concave surface 14 on the substrate 1B. The narrow groove 16 which forms a part of the calibration liquid passage is formed by the above. The narrow groove 16 communicates with the narrow groove 6 formed on one of the substrates 1A through a hole 23 provided in the partition plate 1C when assembled, thereby forming a single calibration liquid passage to form the calibration liquid. The calibrator solution container 13 is pressed against the analyzer to make the discharge portion 13b of the solution container 13 communicate with the test solution passage 2 and to calibrate each terminal of each sensor device of the sensor device 11 prior to measurement of the test solution. When the discharge portion 13b is peeled off by the means, the calibration solution in the calibration solution container 13 flows to the detection portion contact portion 2b in the test solution passage 2. Although not shown in detail in the drawings, the calibration liquid container mounting concave surface 14, the narrow groove 16 forming a part of the calibration liquid passage, and the calibration liquid container 13 receive reagents from the release portion 13 b of the calibration liquid container 13. It goes without saying that various configurations such as providing a guide groove to ensure that the reagent flows into the narrow groove 16 without leaking to other portions when the reagent is discharged are adopted.

Reference numeral 17 denotes a second waste liquid portion formed of a zigzag groove symmetrically formed with the waste liquid portion 4 at a position corresponding to the first waste liquid portion 4 on one substrate 1A. The waste liquid portion 17 communicates with a first waste liquid portion 4 formed on one of the substrates 1A through a hole 24 provided in the partition plate 1C when assembled, and forms one continuous waste liquid passage. (See FIG. 3). Further, at the downstream end of the waste liquid portion 17, an exhaust hole 18 communicating with the outside is formed, and as shown in FIG. 6, the exhaust hole 18 is permeable to air and not to liquid. A plug member 19 that functions as a transmissive member is mounted (FIG. 6 shows a partial cross-sectional view of the exhaust hole 18 in the substrate 1B). The plug member 19 is made of, for example, a porous synthetic resin made of a water-repellent material and containing a water-absorbent resin having a high water-absorbing rate in the pores thereof. When the liquid is injected, when the test liquid reaches the plug member 19, the water-absorbing resin absorbs the test liquid and expands to close each hole of the porous synthetic resin. Is closed, and the test liquid can no longer be injected with the injector. This ensures that the inside of the test liquid passage 2 from the injection hole 3 to the exhaust hole 18 is filled with the test liquid, so that the detection section of the sensor device 11 provided between the injection hole 3 and the exhaust hole 18 The test liquid is reliably supplied.

FIG. 7 is a schematic enlarged view of the sensor device 11. As shown in the drawing, the sensor device 11 includes a plurality of detection units 11b having electrodes formed by applying conductive ink on an insulating substrate 11a. The detection unit 11b includes: an acidity PH, a carbon dioxide partial pressure PCO2, an oxygen partial pressure PO2, sodium Na, potassium K, chlorine Cl, ionized calcium Ca, urea nitrogen B UN, glucose Glu, hematocrit Hct, bicarbonate ion HCO3- Depending on the components to be detected, such as oxygen saturation SO2, total carbon dioxide TCO2, excess base BE, hemoglobin Hgb, etc., the gas component to be detected passes through the portion corresponding to the test solution passage 2 of each electrode. A possible gas permeable membrane and a reagent layer formed by coating a chemical substance or a natural substance that reacts with the component to be detected can be appropriately provided. The detecting unit 11b further includes a counter electrode when a current detection method is used to measure the oxygen partial pressure or glucose concentration in blood, and further includes, for example, hydrogen, sodium or potassium in the test solution. If a potential difference detection method is used to measure the ion concentration of the sample, a reference electrode is further provided, and if the conductivity in the test solution is measured to measure the amount of hematocrit, a reference electrode is used. It can take various forms depending on the component to be detected, such as applying an AC voltage to the rectifier. In the illustrated embodiment, the detectors 11b are arranged so as to be able to measure eight types of inspection values among these inspection values. Each of the detecting portions 11b is connected to terminals 11e arranged along one side edge of the substrate 11a via a conductor 11d formed by applying conductive ink, and these terminals 11e are connected to the housing 1d. Are arranged so as to be exposed to the outside from the substrate 1A when assembled. That is, FIG. 8 is a schematic perspective view showing a state where the housing 1 is assembled. As can be seen from this drawing, the width of one substrate 1A is slightly smaller than that of the other substrate 1B, and the terminals 11e are two When the two substrates 1A and 1B are superimposed, they are arranged on portions of the substrate 1B that protrude from the substrate 1A. The insulating substrate may be made of any insulating material, such as ceramic, glass, glass epoxy, plastic, etc., as long as it is not damaged by the test solution. Plastic films such as vinyl, polyester, polyethylene, and polypropylene are preferable. Further, as a printing method for applying the conductive ink, preferably, a screen printing method capable of efficiently forming a large amount of a uniform material can be considered, but the printing method is not limited thereto, and the ink jet method, the nozzle coating method, and the dispenser may be used. Any method such as printing or casting can be used.

A through-hole 20 is provided at a position on the other substrate 1B corresponding to the through-hole 10 in one of the substrates 1A. When the two substrates 1A and 1B are bonded to each other, the through-holes 10 and 20 are formed. Are aligned and matched.

The partition plate 1C is provided with a plurality of openings 21 at positions along the detecting portion abutting portion 2b and the branch passage 7 of the test liquid passage 2 on the one substrate 1A. The test liquid flowing into the detection portion contact portion 2b and the branch passage 7 is made to come into contact with the detection portions 11c and the electrodes 11b on the other substrate 1B through these openings 21. Further, the partition plate 1C is provided with a hole 22 provided at a position corresponding to the through hole 10 in the one substrate 1A and the through hole 20 on the other substrate 1B, a free end of the narrow groove 6 of the one substrate 1A and the other substrate. The hole 23 for communicating with the free end of the narrow groove 16 of 1B to form one calibration liquid passage, and the waste liquid part 4 of one substrate 1A and the waste liquid part 17 of the other substrate 1B are communicated. A hole 24 for forming a continuous waste liquid portion is provided.

FIG. 9 is a schematic perspective view of a portable analyzer as an embodiment of a test solution analyzer that can use the detector according to the present invention, and FIG. 10 schematically shows internal processing of the analyzer. It is a block diagram. The portable analyzer includes an insertion slot 30 into which the card-type disposable detector illustrated in FIGS. 2 to 8 is inserted, an arithmetic processing unit 31 that performs arithmetic processing on output signals detected by each detection unit in the card-type disposable detector. A storage unit 32 for storing the calculation result of the calculation processing unit 31; a display unit 33 arranged on the upper surface of the casing for displaying data of the calculation result of the calculation processing unit 31; And a printer 34 for printing the data. The operation unit of the apparatus is incorporated in the display unit 33 shown in FIG. 9, and the calibration liquid container pressing means is provided inside the apparatus. The calibration liquid container pressing means is a card-type disposable detector. It can be operated by inserting it.

The operation of the analyzer and the detector configured as described above will be described with reference to a patient's blood analysis as an example. First, the prepared card-type disposable detector is inserted into the insertion port 30 of the portable analyzer, and calibration and measurement of each detector of the sensor device are performed. That is, by inserting the card-type disposable detector, the measurement item is determined, the reagent container pressing means in the portable analyzer is automatically activated, and passes through the opening 9 formed in the substrate 1A of the detector. The calibration liquid container 13 is pressed at a predetermined pressure. As a result, the discharge part 13b of the calibration liquid container 13 is peeled off, and the calibration liquid contained therein is released to the calibration liquid passages 6, 16, and the detection part of the test liquid passage 2 is passed through the calibration liquid passages 6, 16. The calibration liquid flows into the contact part 2b, and comes into contact with the detection part 11b. At this time, the analyzer performs calibration for each detector 11b based on the current value, voltage value, and the like detected from each terminal 11e.

Thereafter, the nozzle of the syringe containing the blood collected from the patient is fitted into the injection hole 3 of the card-type disposable detector, and the blood is injected into the internal test solution passage 2. At this time, since the test liquid passage 2 has a relatively narrow portion 2a on the upstream side of the detecting portion abutting portion 2b and a constricted portion 2c on the downstream side, the blood injection pressure varies. However, the infused blood slowly and stably flows along the detecting portion abutment portion 2b of the test liquid passage 2, and each terminal of the sensor device stably and accurately detects a desired test value. can do. Thus, the blood fluid that has passed through the detection portion abutment portion 2b of the test liquid passage 2 flows from the constricted portion 2c to the first waste liquid portion 4 through the downstream portion 2d. In this case, during the injection of blood by the syringe, the amount of injected blood can be easily recognized by monitoring the state of accumulation of blood in the first waste liquid section 4 from outside. Further, the downstream end of the second waste liquid section 17 connected to the first waste liquid section 4, that is, the exhaust hole 18 formed at the downstream end of the test liquid passage 2, is permeable to air and is liquid-permeable. Since the impervious plug member 19 is mounted on the test sample, even if the blood is injected into the plug member 19 and the test liquid passage 2 becomes full, even if the amount of special blood to be injected is not carefully monitored. The plug member 19 closes the exhaust port 18 so that no more blood can be automatically injected. Unlike the conventional method, in which the injected blood is held in the test device and the calibration operation is performed, and then the test value of the blood held in the test device is measured, unlike the conventional method, the blood injected into the test device is used in the present invention. Since blood measurement values are measured substantially simultaneously with the injection, accurate measurement values can be obtained.

The current value and the voltage value detected by each of the detection units 11b are sent from a terminal 11e to an arithmetic processing unit 31 in the portable analyzer, where they are subjected to arithmetic processing, and are subjected to the acidity PH and the carbon dioxide gas content. Pressure PCO2, oxygen partial pressure PO2, sodium Na, potassium K, chlorine Cl, calcium ion Ca, urea nitrogen BUN, glucose Glu, hematocrit Hct, bicarbonate ion HCO3-, oxygen saturation SO2, total carbon dioxide TCO2, Data relating to various gas concentrations and ion concentrations such as excess base BE and hemoglobin Hgb are output. On the one hand, these data are stored in the storage unit 33 and displayed on the display unit 33 disposed on the upper surface of the casing. Is displayed. These data can be printed out by operating the printer 34 if necessary.

In the illustrated embodiment, the housing 1 is composed of the two substrates 1A and 1B and the partition plate 1C. However, the present invention is not limited to this embodiment, and a configuration in which a test liquid passage can be formed inside. Then, any configuration can be considered. In the illustrated embodiment, the two substrates are entirely made of a transparent or translucent material. However, the present invention is not limited to this embodiment and may be made of an opaque material. Part of the first and second waste liquid portions 4 and 17 may be made of a transparent material so that the state can be confirmed. Further, in this embodiment, the terminals of the sensor device are exposed by forming one substrate to be narrower than the other substrate. You may comprise so that it may be exposed. Further, in the illustrated embodiment, the two substrates are bonded by a partition plate having an adhesive layer on both surfaces, but this is not limited to the present embodiment, and the two substrates can be directly bonded by an adhesive. Good. Further, although the sensor device is provided separately from the housing, a detection unit or the like may be provided directly on the housing. Furthermore, the number of detection units can be arbitrarily set according to the number and type of test values. Further, in the illustrated embodiment, the detection tool is provided with a calibration liquid container having a release section that can be easily peeled off, and is configured so that each detection section can be calibrated before the analysis of the test liquid. Without being limited to the present embodiment, the calibration liquid container may be provided as needed. In addition, even when a calibration solution container is provided, the configuration of the calibration solution container is not limited to the present embodiment.For example, a hole is formed by using a needle-shaped member provided in a housing of an analyzer or a detector during use. The reagent may be configured to be discharged toward the detection section of the test liquid passage.

[0020]

[Effect of the invention]

 The disposable component detector according to the present invention has a test liquid passage inside the housing, a test liquid injection hole is provided at an upstream portion of the test liquid passage, and an exhaust hole is provided at a downstream portion, and the test liquid passage is injected into the test liquid passage. A sensor device capable of detecting at least one component of the test liquid which has been exposed to a portion between the injection hole and the exhaust hole in the test liquid passage, and a terminal portion thereof is provided outside the housing. A stopper member made of a material permeable to air and impermeable to liquid is provided in the exhaust hole so that the test liquid to be analyzed is injected into a syringe or the like. The plug member is made of a material that is permeable to air and impervious to liquid, and the downstream end of the test liquid passage is To prevent leakage of test solution In the operator during injection, especially an effect that the workability is very good since nor to worry injection volume of the test solution. In addition, since the test liquid can be directly injected to the detection part in the test liquid passage, there is no need to provide a part that temporarily holds the test liquid or a mechanism to send the held test liquid to the detection part. In addition, it is possible to simplify the configuration of the analyzer using the detector as well as the detector itself. Further, by forming the plug member from a water-repellent porous synthetic resin body containing a water-absorbing synthetic resin, when the test liquid reaches the plug member at the downstream end of the test liquid passage, the water-absorbing synthetic resin is formed. The resin absorbs the test liquid and expands to close the pores of the porous synthetic resin body, thereby automatically closing the exhaust hole and preventing further injection of the test liquid. Further, a waste liquid portion having a volume capable of storing a predetermined amount of the test liquid is provided at least downstream of the sensor device in the test liquid passage, and the exhaust hole is provided in the waste liquid portion, so that the test liquid to be inspected is provided. The flexibility with respect to the variation of the injection amount can be increased, and the operability and the workability can be facilitated. Furthermore, the injection hole for the test solution is inserted into the nozzle portion of the test solution injector so that the nozzle portion can be fitted in a liquid-tight manner. For example, when the test solution injector is a syringe, the nozzle portion conforms to the JIS standard. If the taper is formed in accordance with the size and shape, the test solution can be injected without touching the atmosphere when the test solution is injected, so that the influence of the atmosphere on the measured values can be avoided and the reliability of the detection data can be improved. Performance can be greatly improved.

[Brief description of the drawings]

FIG. 1A is a schematic top view of a disposable component detector (hereinafter simply referred to as a detector) for a test liquid analyzer according to an embodiment of the present invention, and FIG. (A)
FIG.

FIG. 2 is a schematic development view of the detection tool according to the present invention.

FIG. 3 is a schematic top view of a test liquid passage in the detection tool after the housing is assembled.

FIG. 4 is a partial cross-sectional view of a portion corresponding to the injection hole 3 in the base 1A.

FIG. 5 is an enlarged view of a portion corresponding to the mounting concave surface 14 in the calibration liquid container 13 and the substrate 1B.

FIG. 6 is a partial sectional view of an exhaust hole portion of a substrate 1B.

FIG. 7 is a schematic enlarged view of the sensor device 11;

FIG. 8 is a schematic perspective view showing a state where the housing 1 is assembled.

FIG. 9 is a schematic perspective view showing an embodiment of a portable analyzer that can use the detector according to the present invention.

10 is a block diagram showing a configuration of the portable analyzer shown in FIG.

[Explanation of symbols]

 REFERENCE SIGNS LIST 100 housing 101 test liquid passage 102 injection hole 103 sensor device 104 exhaust hole 105 plug member 106 test liquid injector 106a nozzle portion 1 housing 1A substrate 1B substrate 1C partition 2 test liquid passage 2a relatively narrow width extending from injection hole 3 Part 2b Detecting part abutment part 2c Narrowed part 2d Part extending from narrowed part 2c to first waste liquid part 3 Injection hole 4 Waste liquid part 6 Narrow groove constituting a part of calibration liquid passage 7 Branch passage 8 Through hole 9 Pressing Opening hole for use 10 Through hole 11 Sensor device 11a Substrate 11b Detector 11d Conductor 11e Terminal 12 Concave surface 13 Calibration liquid container 13a Peripheral edge 13b Discharge unit 14 Calibration liquid container mounting concave surface 16 Narrow groove constituting a part of calibration liquid passage 17 2nd waste liquid part 18 exhaust hole 19 plug member 20 through-hole 21 opening 22 through-hole 23 narrow groove 6 Hole 24 first waste portion 4 and the hole 30 insertion opening 31 processing unit 32 storage unit 33 display unit 34 the printer for communicating the second waste fluid section 17 for communicating the beauty 16

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁶ Identification code Agency reference number FI Technical indication location G01N 27/46 371G

Claims (5)

[Utility model registration claims] 1. A test liquid passage is provided inside a housing, a test liquid injection hole is provided in an upstream portion of the test liquid passage, and an exhaust hole is provided in a downstream portion, and at least the test liquid injected into the test liquid passage is provided. A sensor device capable of detecting one component is provided such that the detection portion is exposed at a portion between the injection hole and the exhaust hole in the test liquid passage, and the terminal portion is exposed outside the housing. The exhaust hole is provided with a plug member made of a material permeable to air and impermeable to liquid. A disposable component detector for a test solution analyzer characterized by being configured to be detachably connected to an analyzer capable of analyzing one component. 2. The component detector according to claim 1, wherein the plug member is formed of a water-repellent porous synthetic resin body containing a water-absorbing synthetic resin. 3. The method according to claim 1, wherein the test liquid passage includes a waste liquid part having a volume capable of storing a predetermined amount of test liquid at least downstream of the sensor device, and the exhaust hole is provided in the waste liquid part. The component detector according to claim 1 or 2, wherein 4. The component detection tool according to claim 1, wherein the test liquid injection hole is configured such that a nozzle portion of the test liquid injector can be fitted in a liquid-tight manner. . 5. The test solution passage includes a calibration solution passage branched between a portion where the detection unit of the sensor device is exposed and a test solution injection hole, and an external pressure is applied to an upstream portion of the calibration solution passage. The component detector according to any one of claims 1 to 4, further comprising a calibration liquid container that releases the internal calibration liquid into the calibration liquid passage by pressure.