JP2800585B2 - Blood circulation assist device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood system capable of reducing the burden on the heart by performing a minimally invasive insertion of blood vessels and blood vessels from peripheral blood vessels without performing thoracotomy. The present invention relates to a circulation assist device.

[0002]

2. Description of the Related Art Conventionally, for the treatment of severe heart disease, an artificial heart and a complete artificial heart have been actively studied, and the artificial heart has already been commercialized. However, the application of these techniques requires thoracotomy in earnest and under careful preparation, and is almost ineffective for rescue of emergency patients such as acute myocardial infarction. In order to save the life of these emergency patients, the mechanical assistance of the pumping action of the heart temporarily,
The blood assisted circulation method is used as a method of substituting and recovering the function of the heart. This blood assisted circulation method includes a counterpulsation method.In the systolic phase of the cardiac cycle, the aortic pressure is reduced to reduce the afterload, and blood from the ventricle is helped. By increasing coronary blood flow, it assists the ventricle in which dysfunction has occurred, and aims to improve systemic circulation. As the counterpulsation, an intra-aortic balloon pumping method (IABP) performed by inserting a balloon catheter into the aorta is most commonly performed. However, this intra-aortic counterpulsation method has the drawbacks of reducing cardiac load and increasing coronary blood flow, and has little effect on systemic circulatory support. On the other hand, for the purpose of whole body circulatory support,
Arteriovenous bypass, which draws blood from the artery and pumps the drawn blood into the vein, is used in combination with a membrane oxygen exchange device. Has not been sufficiently fulfilled.

[0003]

SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned drawbacks of the prior art, and has as its object to provide a minimally invasive blood circulation assisting device capable of reducing cardiac load and assisting whole body circulation or cerebral circulation. And

[0004]

Means for Solving the Problems The inventors of the present invention have conducted intensive studies to solve the above-mentioned problems, and as a result, without removing thoracotomy, blood vessels were inserted from peripheral blood vessels into the right atrium. It is found that the above-mentioned object can be achieved by pumping blood from the peripheral blood vessel into the aorta or carotid artery and pumping the blood from the peripheral blood vessel to the aorta or carotid artery. A blood vessel is removed from the blood vessel and inserted into the left atrium through the oval foramen of the right atrium and atrial septum to extract blood.The extracted blood is sent to the blood vessel by the pump, and the blood vessel enters the aorta or carotid artery from the peripheral blood vessel. It has been found that the above object can be achieved by sending blood in such a manner, and based on the findings, the present invention has been completed.

That is, the present invention comprises the following aspects of the invention. 1. A blood vessel that can be inserted into the right atrium from a peripheral blood vessel to extract blood, and a blood vessel that can be inserted into the aorta or carotid artery from the peripheral blood vessel to send blood to the aorta or carotid artery and is driven by the aortic balloon pumping drive A blood vessel to which a balloon is attached and a blood outlet is provided on the downstream side; a blood pump capable of sucking blood from the devascularized vessel and sending blood to the blood vessel; And an oxygen gas exchanger that can be exchanged. 2. A blood vessel that can be inserted from the peripheral blood vessel into the right atrium to extract blood, and a blood vessel that can be inserted into the aorta or carotid artery from the peripheral blood vessel to send blood to the aorta or carotid artery, and a blood outlet on the downstream side A blood vessel, a blood pump capable of sucking blood from the blood removal vessel and pumping the blood to the blood vessel, an oxygen gas exchanger capable of exchanging carbon dioxide in blood with oxygen, and a blood vessel. A blood circulation assisting device, comprising: a blood outflow adjusting mechanism capable of controlling the degree of opening of the blood outlet so that the blood outflow from the downstream side blood outlet satisfies the following expression. 0.1 ≦ Fp / (Fd + Fp) ≦ 0.5 (where Fd indicates the blood outflow from the distal end of the blood vessel,
p indicates the amount of blood flowing out from the blood outlet on the downstream side of the blood vessel. ) 3. A blood vessel that can be inserted from the peripheral blood vessel into the right atrium to extract blood, and a blood vessel that can be inserted into the aorta or carotid artery from the peripheral blood vessel to send blood to the aorta or carotid artery, and a blood outlet on the downstream side A blood vessel having a blood vessel, wherein at the time of blood vessel insertion, a blood vessel whose inner cylinder closing the blood discharge port on the blood vessel downstream side is inserted into the blood vessel downstream side tube,
A blood circulation assist comprising a blood pump capable of sucking blood from the blood removal vessel and sending blood to the blood supply vessel, and an oxygen gas exchanger capable of exchanging carbon dioxide in blood for oxygen. apparatus. 4. With a puncture core at the tip, a devascularization that can be inserted into the left atrium from the peripheral blood vessels through the foramen ovale of the right atrium and atrial septum to extract blood, and a peripheral blood vessel inserted into the aorta or carotid artery A blood vessel that can pump blood to the aorta or carotid artery and has a blood outlet on the downstream side,
A blood circulation assist comprising: a blood pump capable of sucking blood from the blood removal vessel and pumping blood to the blood supply vessel; and an oxygen gas exchanger capable of exchanging carbon dioxide in blood for oxygen. apparatus. 5. Item 5. The blood circulation assistance according to Item 4, wherein the inner cylinder closing the blood discharge port on the downstream side of the blood vessel when the blood vessel is inserted is the blood vessel inserted into the downstream tube. apparatus. 6. With a puncture core at the tip, a devascularization that can be inserted into the left atrium from the peripheral blood vessels through the foramen ovale of the right atrium and atrial septum to extract blood, and a peripheral blood vessel inserted into the aorta or carotid artery A blood vessel that can pump blood to the aorta or carotid artery and has a blood outlet on the downstream side,
A blood pump capable of sucking blood from the blood removal vessel and pumping the blood to the blood supply vessel, an oxygen gas exchanger capable of exchanging carbon dioxide in the blood with oxygen, and a blood discharge port on the downstream side of the blood supply vessel A blood outflow adjusting device capable of controlling the degree of opening of the blood outlet so that the outflow of blood satisfies the following expression. 0.1 ≦ Fp / (Fd + Fp) ≦ 0.5 (where Fd indicates the blood outflow from the distal end of the blood vessel,
p indicates the amount of blood flowing out from the blood outlet on the downstream side of the blood vessel. )

Hereinafter, the present invention will be described in detail. In the present invention, it is necessary that the blood removal vessel and the blood supply vessel can be inserted from a peripheral blood vessel. As the peripheral blood vessel into which the blood vessel is removed and the blood vessel is inserted according to the present invention, it is preferable to select a peripheral blood vessel located near the skin and having a large diameter. Most preferred is a vein, hip, iliac, carotid or subclavian vein.
In this way, the use of a blood removal vessel and a blood vessel that can be inserted from a peripheral blood vessel that is close to the skin allows the blood to be withdrawn very easily without performing thoracotomy surgery, that is, without significantly damaging the body. And feed. The removal of blood vessels and the insertion of blood vessels into peripheral blood vessels may be performed percutaneously, or may be performed by exposing blood vessels surgically. It is preferable to perform the removal of the blood vessels and the insertion of the blood vessels while seeing through.

The blood removal vessel of the present invention is not particularly limited as long as it has a function of extracting blood, and various tubes can be used. Those having a mouth are preferred. This devascularization is preferably inserted from a peripheral venous vessel. The outer diameter of the devascularization vessel of the present invention must be such that it can be inserted into peripheral blood vessels and does not obstruct the flow of blood in the inserted blood vessels as much as possible, and usually has an outer diameter of 5 to 20 mm. Is used. The inner diameter of the blood removal vessel of the present invention depends on the amount of blood circulation to be assisted, but usually about 4 to 18 mm. The length of the devascularized blood vessel of the present invention is required to be long enough to be inserted from a peripheral blood vessel and reach the right atrium or the left atrium.
A length of 100 cm is used.

[0008] The blood supply vessel of the present invention is not particularly limited as long as it has a function of sending out blood and has a blood discharge port on the downstream side. Can be used. The position of the blood ejection port provided on the downstream side is not particularly limited as long as it is on the downstream side of the blood vessel.
A range of 60 cm is preferred. Further, the blood supply vessel preferably has a blood discharge port at the distal end as another blood discharge port other than the blood discharge port provided on the downstream side. Further, it is preferable that a blood outflow amount adjusting mechanism is provided at the blood discharge port on the downstream side of the blood vessel. Examples of the blood outflow adjusting mechanism include various blood outflow adjusting mechanisms such as a valve and an orifice. It is preferable to control the opening degree of the blood outlet so that the blood outflow amount from the blood outlet on the downstream side of the blood vessel satisfies the following expression. 0.1 ≦ Fp / (Fd + Fp) ≦ 0.5 (where Fd indicates the amount of blood flowing out from the distal end of the blood vessel.
p indicates the amount of blood flowing out from the blood outlet on the downstream side of the blood vessel. )

When the value of the above equation is less than 0.1, blood flow becomes difficult and blood circulation in the lower limb is easily hindered, which may lead to necrosis. It becomes more difficult to send the required blood volume. In order to control the blood outflow in this range, the strength and structure of valves and orifices can be appropriately selected.
Furthermore, when inserting a blood vessel, it is preferable that the inner tube is inserted into a tube on the downstream side of the blood vessel so that the blood discharge port on the downstream side of the blood vessel can be closed. At the time of insertion of a blood vessel, blood pressure may increase and blood may blow out from the blood outlet, but by inserting this inner tube and closing the blood outlet with the inner tube, blood is surely blown out. Can be prevented. A balloon is attached to the blood supply vessel, and aortic balloon pumping (IAB) is performed.
P) It is preferable to have a function. When a balloon is attached to the blood vessel, it is preferable to attach a peel-off type sheath to the outside of the blood vessel because it can be easily inserted into the blood vessel. The vessel is inserted into the vessel with its outside covered by a peel-off sheath, and then the sheath is peeled off and removed.

[0010] The outer diameter of the blood vessel of the present invention must be such that it can be inserted into a peripheral blood vessel and does not obstruct the flow of blood in the introduced blood vessel as much as possible. A material having an outer diameter of? Also,
The inner diameter of the blood supply tube of the present invention may be appropriately selected depending on the amount of blood circulation to be assisted. You. When an oscillating blood pump is used as the blood pump, the one having an inner diameter of about 2 to 10 mm can be used. The length of the blood supply vessel of the present invention is required to be long enough to reach the aorta or carotid artery by insertion from a peripheral blood vessel, but a length of 30 to 120 cm is usually used. The blood removal vessel and the blood vessel according to the present invention are preferably provided with a fitting for connecting to a blood pump or a gas exchanger. In addition, a branch, a cock, and the like can be attached to the hand of the blood vessel and the blood vessel to remove bubbles at the time of insertion. When percutaneously inserting the blood removal vessel and blood vessel of the present invention from the peripheral blood vessel, attach a hemostatic device to the blood removal vessel and blood vessel so that blood does not flow from the interface between the blood vessel and the blood vessel and the blood vessel. Is preferred. As this hemostatic device,
For example, a hemostatic sheath and the like can be mentioned.

The material of the blood removal vessel and the blood supply vessel of the present invention is not particularly limited, and various materials such as a material conventionally used as a heart cannula can be applied. For example, soft polyvinyl chloride, silicon, Examples thereof include polyethylene, polypropylene, and polyurethane, but it is preferable that the material is as soft as possible. In addition,
It is desirable that the blood removal vessel of the present invention be reinforced spirally with a linear material such as metal or hard resin. Further, the inner and outer surfaces of the blood removal vessel and the blood vessel of the present invention which come into contact with blood are preferably antithrombotic because they can be used continuously for a long period of time, and are made of, for example, an antithrombotic material such as polyurethane and cardiosan. Or an antithrombotic treatment such as immobilization or sustained release of an antithrombotic material such as heparin, urokinase, h-TPA. In addition, it is preferable that a contrast agent is applied to or mixed with the blood removal vessel and blood supply vessel of the present invention. In the present invention, a blood pump capable of sucking blood from a blood removal vessel and sending blood to a blood supply vessel is required.

Examples of the blood pump include a pulsating pump such as a diaphragm pump, a sack pump, a tube pump and a pusher plate pump, a vibration pump such as a permanent magnet vibration pump, a roller pump, and a centrifugal pump. Various pumps can be used, but a vibrating pump that is extremely effective for blood circulation to peripheral blood vessels even if the blood vessels are thin is preferable. In order to further enhance the effects of reducing the cardiac load and increasing the coronary blood flow, it is preferable to attach a balloon to the blood supply vessel to have an aortic balloon pumping function. Since the pump of the present invention is mounted outside the body, the device of the present invention can be quickly mounted on an emergency patient. The present invention includes a mode using a devascular that can be inserted into the right atrium as in the first mode and a mode using a devascular that can be inserted into the left atrium as in the second mode. The former will be described sequentially. In the first aspect of the present invention, there is a need for a blood vessel that can be inserted into a right atrium from a peripheral blood vessel.

In the first embodiment of the present invention, when a blood vessel is inserted into the aorta, the blood vessel can be inserted directly from the peripheral artery into the aorta. Can be inserted into the aorta via the foramen ovale and left atrium. In the latter case, when the devascularized vessel and the blood vessel are inserted into the right atrium by the same route, two separate blood vessels and the blood vessel may be separately inserted from the peripheral blood vessel. It is preferable to use a heavy pipe because the operation is easy. In the case of a double tube, either the outer tube or the inner tube may be devascularized, but it is preferable that the outer tube be devascularized. If the outer vessel is avascular, the avascular vessel is shorter than the inner vessel and blood can be drawn from the right atrium. In addition, the inner blood vessel has a single tube with no external devascularization at the distal end, and the single blood vessel portion penetrates through the foramen ovale of the atrial septum and is inserted into the left atrium. . When the blood vessel is inserted into the carotid artery, the blood vessel is preferably inserted directly from the carotid artery.

When a blood vessel is inserted into the aorta via the foramen ovale and left atrium, it is preferable to attach a puncture core to the distal end of the blood vessel. Thus, the blood vessel can easily penetrate the foramen ovale. The tip of the puncture core is appropriately bent so that it can easily penetrate the foramen ovale. The foramen ovale is open when you are a fetus,
This method is extremely excellent because it is a part that closes at birth and does not damage the heart itself even if it penetrates. The puncture core is made of a flexible material, and when inserted into a blood vessel, has a substantially linear shape so as not to obstruct insertion of a blood vessel. The blood vessel and the puncture core may be manufactured by integral molding. Further, it is preferable that a puncture needle is inserted into the puncture core through a hole of a guide wire provided therein to pierce the foramen ovale. This makes it easier to pierce the foramen ovale. When the blood vessel is inserted into the left atrium via the foramen ovale, it is preferable to attach a detachment prevention device so that the inserted blood vessel does not fall out of the foramen ovale. As the detachment preventing device, various detachment preventing devices can be used, and examples thereof include a balloon and a male record.

In the first aspect of the present invention, an oxygen gas exchanger capable of exchanging carbon dioxide in blood for oxygen is required. This oxygen gas exchanger may be attached before and after the blood pump. As an oxygen gas exchanger,
Various types can be used, but a membrane oxygen gas exchanger is preferable. When an oxygen gas exchanger is used, it is preferable that the oxygen gas exchange rate can be increased by passing the oxygen gas exchanger while vibrating the blood using a vibration pump.

In addition, instead of the blood vessel of the first embodiment of the present invention, a blood vessel that can be inserted into a right ventricle or a pulmonary artery from a peripheral blood vessel is used, and blood deprived from the right atrium is replaced with an oxygen gas exchanger. When the operation of pumping the blood into the right ventricle or the blood vessel inserted into the pulmonary artery by the pump after the passage, the lung assist or the lung assist and the right ventricular assist can be performed. In this case, the blood removal vessel and the blood supply vessel may be separately inserted from the peripheral blood vessel, but it is preferable to form the blood removal vessel and the blood supply vessel into a double tube as described above. In a second aspect of the present invention, there is a need for a devascularization that can be inserted from peripheral blood vessels through the vena cava and further into the left atrium through the foramen ovale of the right and atrial septum. It is preferable to attach a puncture core to the distal end of the devascularized vessel.
Thereby, the devascularization can easily penetrate the foramen ovale. The tip of the puncture core is appropriately bent so that it can easily penetrate the foramen ovale. The bending of the tip of the puncture core is not particularly limited.
An arc shape of / 10 to 1/4 is usually used. The puncture core has a structure that can normally penetrate the interior of a blood removal vessel like the puncture core of the first aspect, and preferably has a structure that can freely enter and exit the blood removal vessel. Further, this puncture core is made of a flexible material similar to that of a blood vessel, and becomes substantially linear when penetrating the blood vessel so as not to hinder insertion of a blood vessel.

Further, it is preferable that a puncture needle is inserted into a puncture core through a hole of a guide wire provided therein to penetrate the foramen ovale. This makes it easier to penetrate the foramen ovale. In addition, it is preferable that the puncture needle and the puncture needle are manufactured by integral molding because the puncture needle is hard to be detached from the puncture core. Further, it is preferable to attach a detachment prevention device to the devascularization vessel so that the inserted devascularization does not fall out of the foramen ovale. Examples of the detachment prevention device include a balloon and a male record. In the second embodiment of the present invention, when the devascularization is to be inserted into the right atrium, it may be inserted from the peripheral blood vessel while the puncture core is inserted inside the devascularization. After reaching the right atrium, a puncture core may then be inserted inside the devascularization vessel. It is preferable to attach a balloon near the distal end of the devascularization vessel and slightly inflate the balloon when inserting the devascularization vessel from the peripheral blood vessel, since the devascularization can easily reach the right atrium along the flow of blood. In the second embodiment of the present invention, an oxygen gas exchanger is not required, but an oxygen gas exchanger may be used.

[0018]

According to the present invention, blood is extracted by using a blood removal vessel that can be inserted into the right atrium from a peripheral blood vessel, and blood that is drawn by using a blood supply vessel that can be inserted into the aorta or carotid artery from the peripheral blood vessel. After oxygen gas exchange, it can be sent to the aorta or carotid artery,
It has made it possible to support the lungs, reduce the burden on the heart, and assist the whole body or the brain. Also,
The present invention provides for the extraction of blood from peripheral vessels into the right atrium, through the foramen ovale of the atrial septum into the left atrium, to withdraw blood and to pump the aorta or carotid artery from the peripheral vessels. As a result, it has become possible to reduce the burden on the heart and to assist the circulation of the whole body or the brain. Hereinafter, embodiments of the present invention will be described more specifically with reference to the drawings. However, the present invention is not limited by these examples.

[0019]

FIG. 1 is a perspective view showing an example of a blood removal vessel according to the present invention. A nylon spiral 3 is wound around the main body of the blood removal vessel 1 made of polyurethane and having an outer diameter of 8 mm and an inner diameter of 7 mm, and is reinforced. A blood extraction port 2 for extracting blood is provided at the distal end of the blood removal vessel 1. Further, a balloon 4 is attached to the distal end of the devascularization vessel 1, and the balloon 4 is connected to a balloon connector 6. The balloon 4 is inflated by taking helium gas in and out of the balloon connector 6,
You can wither. The balloon 4 can be prevented from falling out of the foramen ovale by inflating the vein 1 after piercing the foramen ovale of the atrial septum. On the other hand, a connector 5 for connection with a pump is attached to the base of the blood removal vessel 1. FIG. 2 is a perspective view showing another example of the blood removal vessel of the present invention. In this example, a male recorder 7 is attached in place of the balloon 4 in FIG.
The male record 7 as shown in FIG. 2 is a state diagram when the external force is removed, but when an external force such as to stretch the devascularization 1 is given,
The blood vessel 1 is extended in the longitudinal direction so that the protrusion is eliminated.

FIG. 3 is a perspective view showing an example of the blood vessel of the present invention. A blood sending port for sending blood is attached to the distal end of a blood supply vessel 8 made of polyurethane and having an outer diameter of 7 mm and an inner diameter of 6 mm, and a balloon 10 is attached to the back of the distal end. This balloon 10
Is connected to a balloon connector 12 having an outer diameter of 2 mm, and can be inflated or deflated by helium gas taken in and out of the balloon connector 12. The balloon 10 is a balloon for counterpulsation, and can send blood with pulsation to the whole body. In addition, a flap valve is provided in front of the balloon 10 on the downstream side of the blood vessel, and forms a blood discharge port 11. FIG. 4 is a sectional view showing an example of the puncture core of the present invention. The tip of the puncture core 13 is bent,
Easy to penetrate the foramen ovale. A guide wire 14 is inserted inside the puncture core 13, and a puncture needle 15 is provided at the tip of the guide wire 14 to make it easier to penetrate the oval hole. The guide wire 14 is used for the puncture core 1
The puncture needle 15 can be positioned at the tip of the puncture core 13 by taking the inside of the puncture needle 3 in and out.

FIG. 5 is a perspective view showing a state where the puncture core 13 is inserted into the interior of the blood removal vessel 1 of the present invention. Puncture lead 13
Can be inserted into and removed from the interior of the devascularization vessel 1 and is inserted up to the distal end of the devascularization vessel 1.
The tip is bent according to the shape of. FIG. 6 shows FIG.
FIG. 2 is a perspective view showing a state in which the puncture core 13 of FIG. Since the puncture core 13 has been pulled out of the blood removal vessel 1, a male tape 7 projects from the distal end of the blood removal vessel 1 in the width direction of the blood removal vessel 1.

FIG. 7 is a schematic view when the blood circulation assisting device according to the second embodiment of the present invention is attached to the body. Devascularization 1
Is inserted into the body from the crotch vein 25, is inserted into the left atrium 21 via the inferior vena cava 16, the right atrium 18 and the foramen ovale 19. On the other hand, the blood supply vessel 8 is inserted from the hip artery 26 and inserted into the aorta 24. The blood extracted from the blood removal vessel 1 is sent out to the aorta through the blood supply vessel 8 via the oscillating blood pump. Blood is pumped out in response to the movement of the heart, so as not to strain the heart. The inflation and deflation of the balloon 10 is preferably synchronized with the heart cycle by a balloon drive that can be synchronized with the heart cycle. Further, a blood outlet 11 is provided at the branch point of the aorta and the hip artery on the downstream side of the blood supply vessel 8, and the blood outflow from the blood outlet 11 is 20% of the total blood outflow. %Met. In FIG. 7, a balloon is not attached near the distal end of the devascularization vessel 1. However, the balloon with the balloon attached is inflated by inflating the balloon after the devascularization reaches the left atrium. Can be prevented from falling out. FIG. 8 is a schematic diagram when the blood circulation assist device of the first embodiment of the present invention is attached to the body.

The avascularized vessel 1 is inserted into the body through the hip vein 25 and passes through the inferior vena cava 16 into the right atrium 18.
On the other hand, the blood vessel 8 is inserted from the hip artery 26 and
Has been inserted. The blood extracted from the blood removal vessel 1 is sent to the aorta via the oscillating blood pump and the oxygen gas exchanger. Others are the same as FIG. Although the oxygen gas exchanger is arranged after the oscillating blood pump in the figure, it may be arranged before the oscillating blood pump. FIG. 9 is a sectional view of a two-stage permanent magnet type oscillating flow blood pump used in the blood circulation assisting device of the present invention.
An oscillating flow pump is a pump that can obtain a pumping action by vibrating a pipe in the pipe axis direction.

The vibrating tube 32 has left and right support springs 33.
, And a spring valve is provided at one end, and vibrates in the tube axis direction by magnetic force. The vibration force is applied to the vibration tube 32
Is obtained by changing the bias magnetic field generated by the permanent magnet 34 on the outer periphery of the magnetic field by the magnetic field generated by the electromagnetic coil 35. The amplitude and amplitude of the vibrating tube can be controlled by the current value of the coil and its frequency. The sliding part of the blood pump is sealed with a bellows 36 and a rubber film, so that blood cells can be prevented from being destroyed. The blood is sucked from the suction port 37 on the right side of the vibration pump, and the pressure of the blood rises due to the vibration of the vibration tube 32, the spring valve is opened, and the blood in the vibration tube moves into the spring valve chamber (the casing 30). The valve then closes as the pressure in the vibrating tube decreases, and the blood in the spring valve chamber is discharged from the discharge port 38 by the piston effect due to the leftward movement of the vibrating tube 32.

[0025]

According to the blood circulation assisting device of the present invention, it is possible to attach the patient to the patient very easily without performing a thoracotomy and to assist the blood circulation. When the blood removal is performed by inserting the blood removal vessel of the present invention into the right atrium and extracting blood and inserting the blood supply vessel into the aorta or carotid artery to supply blood, the support of the lungs, the reduction of cardiac load, the increase of coronary blood flow and the support of general circulation It can support the circulation of the brain. In the case where the blood removal vessel of the present invention is inserted into the left atrium to draw out blood, and the blood supply vessel is inserted into the aorta or carotid artery to feed blood, the burden on the heart can be reduced, coronary blood flow can be increased, and circulatory support of the whole body or cerebral circulatory can be achieved. It can be performed.

[Brief description of the drawings]

FIG. 1 is a perspective view showing an example of a blood removal vessel of the present invention.

FIG. 2 is a perspective view showing another example of the blood removal vessel of the present invention.

FIG. 3 is a perspective view showing an example of a blood vessel according to the present invention.

FIG. 4 is a sectional view showing an example of a puncture core according to the present invention.

FIG. 5 shows a puncture core 13 inside the blood removal vessel 1 of the present invention.
It is a perspective view which shows the state which inserted.

FIG. 6 is a perspective view showing a state in which the puncture core 13 of FIG.

FIG. 7 is a schematic diagram when the blood circulation assisting device according to the second embodiment of the present invention is attached to a body.

FIG. 8 is a schematic diagram when the blood circulation assisting device according to the first embodiment of the present invention is attached to a body.

FIG. 9 is a sectional view of a vibration pump used in the blood circulation assisting device of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Devascularization 2 Blood extraction port 3 Spiral 4 Balloon 5 Connector 6 Balloon connector 7 Maleco 8 Blood supply vessel 9 Blood supply port 10 Balloon 11 Blood outlet 12 Balloon connector 13 Puncture core 14 Guide wire 15 Puncture needle 16 Lower vena cava 17 Upper Vena cava 18 right atrium 19 oval foramen 20 right ventricle 21 left atrium 22 pulmonary artery 23 left ventricle 24 aorta 25 hip vein 26 hip artery

Claims (6)

(57) [Claims] 1. A blood vessel that can be inserted from a peripheral blood vessel into the right atrium to extract blood, and a blood vessel that can be inserted into the aorta or carotid artery from a peripheral blood vessel to send blood to the aorta or carotid artery, and aortic balloon pumping Driven by the drive
A blood vessel having a balloon attached thereto and having a blood discharge port on the downstream side, a blood pump capable of sucking blood from the devascularized vessel and sending blood to the blood vessel, and a carbon dioxide in the blood. A blood circulation assist device comprising an oxygen gas exchanger capable of exchanging oxygen. 2. The blood is drawn by inserting it into the right atrium from a peripheral blood vessel.
Prolapsed vessels and aorta or neck from peripheral vessels
Can be inserted into an artery to send blood to the aorta or carotid artery
And a blood vessel having a blood outlet on the downstream side,
Aspirates blood from the devascularization vessel and pumps blood to the blood vessel
A blood pump that can oxygenate carbon dioxide in the blood
Can be exchanged with the oxygen gas exchanger and the downstream side of the blood vessel
So that the blood outflow from the blood outlet of the part satisfies the following formula
In addition, a blood outflow regulator that can control the degree of opening of the blood outlet
A blood circulation assist device, comprising: 0.1 ≦ Fp / (Fd + Fp) ≦ 0.5 (where Fd indicates the blood outflow from the distal end of the blood vessel,
p indicates the amount of blood flowing out from the blood outlet on the downstream side of the blood vessel.
You. ) 3. The blood is drawn from a peripheral blood vessel by inserting it into the right atrium.
Prolapsed vessels and aorta or neck from peripheral vessels
Can be inserted into an artery to send blood to the aorta or carotid artery
Blood vessels with a blood outlet on the downstream side
Therefore, when inserting a blood vessel, the blood discharge port on the downstream side of the blood vessel is
When the inner tube to be closed is inserted into the downstream tube of the blood vessel,
Blood from the blood vessel and the blood removal vessel,
Blood pump that can pump out and carbon dioxide in the blood
From an oxygen gas exchanger that can exchange oxygen for oxygen
A blood circulation assisting device characterized in that: 4. A puncture core at the distal end, which extends from peripheral blood vessels to the right atrium.
Blood through the foramen ovale of the atrial septum and into the left atrium.
The avascular or aortic or peripheral vessels that can be pumped out
Can be inserted into the carotid artery to pump blood into the aorta or carotid artery
Blood supply with a blood outlet on the downstream side
Blood from the vessel and the blood vessel from the blood removal vessel,
Blood pump that can pump out and carbon dioxide in the blood
An oxygen gas exchanger that can exchange oxygen with oxygen.
A blood circulation assist device, characterized in that: 5. A blood vessel downstream side of a blood vessel when the blood vessel is inserted.
The inner cylinder that closes the blood outlet of the blood vessel is inserted into the tube on the downstream side of the blood vessel.
5. The blood vessel which has been inserted.
Blood circulation assist device. 6. A puncture core at a distal end, which is connected to a peripheral vessel to a right atrium.
Blood through the foramen ovale of the atrial septum and into the left atrium.
The avascular or aortic or peripheral vessels that can be pumped out
Can be inserted into the carotid artery to pump blood into the aorta or carotid artery
Blood supply with a blood outlet on the downstream side
Blood from the vessel and the blood vessel from the blood removal vessel,
Blood pump that can pump out and carbon dioxide in the blood
An oxygen gas exchanger that can exchange blood with oxygen
The blood outflow from the blood outlet on the downstream side of the tube satisfies the following formula.
Blood outflow that can control the degree of opening of the blood outlet
Blood circulation assist device having a volume adjustment mechanism
Place. 0.1 ≦ Fp / (Fd + Fp) ≦ 0.5 (where Fd indicates the blood outflow from the distal end of the blood vessel,
p indicates the amount of blood flowing out from the blood outlet on the downstream side of the blood vessel.
You. )