JP3265650B2 - Blood circulation assist device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood circulation assisting device capable of directly sending blood to a coronary artery or the like. The present invention relates to a blood circulation assisting device capable of sending blood directly to a coronary artery or the like.

[0002]

2. Description of the Related Art Conventionally, in order to save the life of an emergency patient such as acute myocardial infarction, the blood assisted circulation method has been used as a method of temporarily assisting and substituting the pumping action of the heart mechanically to restore the function of the heart. Forcibly circulating blood through a coronary artery or the like has been performed. This blood assisted circulation method includes a counterpulsation method.In the systolic phase of the cardiac cycle, the aortic pressure is reduced to reduce the afterload, and blood from the ventricle is helped. By increasing coronary blood flow, it assists the ventricle in which dysfunction has occurred, and aims to improve systemic circulation. As the counterpulsation, an intra-aortic balloon pumping method (IABP) performed by inserting a balloon catheter into the aorta is most commonly performed. However, this intra-aortic counterpulsation method sometimes failed to sufficiently increase coronary blood flow. On the other hand, an arteriovenous bypass method in which blood is drawn out from an artery or vein with a catheter for the purpose of assisting blood circulation and the drawn blood is sent to an artery or vein such as a coronary artery through a catheter by a pump is used in combination with a membrane oxygen exchange device. Have been. However,
This method has a drawback that the blood is passed through an elongated catheter, so that the pressure loss is large, and the objects of circulatory support and reduction of cardiac load cannot be sufficiently achieved.

[0003]

SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and has been made in view of the above circumstances, and has been made in view of the above circumstances. It is an object of the present invention to provide a blood circulation assisting device with less blood circulation.

[0004]

Means for Solving the Problems As a result of intensive studies to solve the above-mentioned problems, the present inventor has found that a discharge port or a suction port provided at a distal end portion of a catheter having a blood passage therein has a hand portion. The suction port or the discharge port is provided at a position within 40 cm in the direction of, a check valve is provided between the discharge port and the suction port, and further by providing a specific blood sending means, it is found that the above object can be achieved. Based on the knowledge, the present invention has been completed. That is, the present invention provides: (1) a blood circulation assisting device having a catheter having a blood passage therein and blood feeding means, wherein the catheter has a discharge port at a distal end thereof, and a discharge port is provided from the discharge port to a hand section. Has a suction port in the portion of the catheter wall within 20 cm in the direction,
A check valve is provided at the discharge port or in the blood passage between the discharge port and the suction port, and the blood feeding means can sequentially and repeatedly close and penetrate the blood path substantially before or after the suction port. A catheter balloon mechanism in which a balloon is mounted in the blood passage, or a blood passage volume variation mechanism capable of sequentially repeating reduction and restoration of the volume of the blood passage before or after the suction port. (2) The blood circulation assisting device according to (1), wherein the balloon is formed of an oxygen gas permeable membrane. (3) A catheter having a blood passage therein and blood feeding means. A blood circulation assisting device, having a suction port at the distal end of the catheter, having a discharge port in a portion of the catheter wall within 20 cm in the direction of the hand from the suction port,
A check valve is provided at the suction port or in the blood passage between the suction port and the discharge port, and the blood feeding means can sequentially and repeatedly close and penetrate the blood path substantially before or after the discharge port. A catheter balloon mechanism in which a balloon is mounted in the blood passage, or a blood passage volume variation mechanism capable of sequentially repeating reduction and restoration of the volume of the blood passage before or after the discharge port. (4) The blood circulation assisting device according to (3), wherein the balloon is formed of an oxygen gas permeable membrane.

Hereinafter, the present invention will be described in detail. Application No. 1
In the blood circulation assisting device of the present invention, a discharge port is provided at a distal end portion of a catheter having a blood passage therein. The distal end of the catheter provided with the discharge port means not only the distal end of the catheter but also the peripheral portion of the distal end of the catheter, and the mounting position of the discharge port is preferably the distal end. The shape and size of the discharge port are not particularly limited as long as the shape and size can be inserted into a target department and can discharge blood, but the shape is preferably circular or elliptical,
The size is preferably larger, but may be appropriately selected according to the size of the catheter diameter. In addition, the tip may have a curved shape to improve the controllability of the direction. The tip can be softened so as not to damage the tissue, and the diameter of the tip can be reduced.

[0006] In the blood circulation assisting apparatus of the first invention of the present application, a suction port is provided at a portion within 40 cm in the hand direction from a discharge port provided at the distal end of the catheter. The position where the suction port is provided is within a range of 40 cm in the hand direction from the discharge port, preferably within a range of 20 cm, particularly preferably within a range of 10 cm. Since the positions of the discharge port and the suction port are short, pressure loss can be reduced. The shape and size of the suction port are not particularly limited as long as the shape and size can suck blood, and may be appropriately selected according to the diameter, thickness, and material of the catheter. The number of suction ports may be one, or two or more. When a plurality of suction ports are provided, the suction ports may be arranged in the longitudinal direction of the catheter, may be arranged in the outer circumferential direction of the catheter, or may be a combination thereof. It should be noted that a check valve may be provided at the suction port to suck blood but prevent blood once sucked from leaving the suction port. Thereby, blood can be more efficiently discharged.

The catheter used in the blood circulation assisting device of the first invention of the present application has a blood passage therein, and this blood passage needs to be at least between the discharge port and the suction port. It may be in the form of a tube extending from the distal end of the catheter to the entire length of the proximal portion. The cross-sectional shape of the catheter is not particularly limited, but is circular,
A shape such as an ellipse or a polygon is preferred, and a circle is particularly preferred. The outer diameter of the catheter of the present invention is preferably such that it can be inserted into peripheral blood vessels and does not obstruct the flow of blood in the inserted blood vessels as much as possible.
Those having an outer diameter of ２０20 mm are used. The inner diameter of the catheter of the present invention depends on the amount of blood circulation to be assisted. Since the amount of blood circulation is usually about 250 milliliters / minute, a catheter having a diameter of about 2 to 18 mm is usually used. The length of the catheter of the present invention may be determined by appropriately selecting the length necessary for insertion from a peripheral blood vessel to reach various arteries and veins. The material of the catheter of the present invention is not particularly limited, and various materials such as a material conventionally used as a heart cannula can be applied. For example, soft polyvinyl chloride, silicon, polyethylene, polypropylene, polyurethane, polyamide And the like. It is desirable that the catheter of the present invention be spirally reinforced with a linear material such as metal or hard resin. Further, the inner and outer surfaces of the catheter of the present invention that come into contact with blood are preferably used because they have antithrombotic properties and can be used continuously for a long period of time.For example, polyurethane or cardiosan may be composed of an antithrombotic material, Alternatively, it is preferable that an antithrombotic treatment such as immobilization or sustained release of an antithrombotic material such as heparin, urokinase, h-TPA has been performed.

[0008] The vascular circulation assistance device of the first invention of the present application has a check valve in the discharge port or in a blood passage between the discharge port and the suction port. The check valve provided at the discharge port has a function of discharging blood from the discharge port but not sucking external blood. Thereby, the blood can be discharged efficiently. The check valve provided in the blood passage between the discharge port and the suction port can send blood in the direction of the discharge port provided in the tip portion, but on the contrary, it can send blood in the direction of the suction port. It has a function that cannot be performed.
The check valve is not particularly limited and various check valves can be used. For example, a blow-off valve, a tricuspid valve,
A disc valve and the like are mentioned, and a valve device (hereinafter, referred to as a jellyfish valve) already proposed by the present applicant in JP-A-2-82981 is also preferably used. The check valve may be attached to the discharge port or in the blood passage between the discharge port and the suction port, but is preferably closer to the discharge port. Further, the check valve may be attached to any one of the outlet or the blood passage between the outlet and the inlet, or may be attached to both.

[0009] The blood circulation assisting apparatus of the first invention of the present application has blood sending means. There are two modes of this blood delivery means: an intra-catheter balloon mechanism or a blood passage volume variation mechanism. The intra-catheter balloon mechanism is a mechanism in which a balloon capable of sequentially closing and penetrating the blood passage before or after the suction port is mounted in the blood passage. The balloon may be adhered and attached to the inner wall of the blood passage, or may be floated and attached in the blood passage, but is preferably adhered to the inner wall. Also, the balloon may be attached so that the blood passage can be substantially closed and penetrated before or after the suction port, and attached to the tip side or near hand side of the suction port, and the suction port is provided when the balloon is inflated. Although it may be one that can substantially block the blood passage at the same time as the air is blocked, it is preferable to attach the balloon so that the balloon does not cover the suction port when the balloon is inflated. As described above, a check valve may be provided at the suction port to suck blood but prevent blood once sucked from flowing out of the suction port. In particular, when the suction port is between the check valve provided in the blood passage and the balloon, it is preferable to provide a check valve at the suction port. By inflating or deflating the balloon attached in this way, or by repeating this operation sequentially, it is possible to successively substantially close and penetrate the blood passage. The term “substantially occluded” means not only complete occlusion but also occlusion having some clearance. It is preferable that there be a clearance, since the blood is easily sucked from the suction port when the balloon is provided between the check valve and the suction port.

[0010] In the intra-catheter balloon mechanism, a check valve that can send out blood in the direction of the discharge port but does not flow blood in the direction of the suction port into the blood passage between the balloon and the suction port. An additional attachment may be used to ensure blood delivery by balloon inflation. When this balloon is composed of an oxygen gas permeable membrane and oxygen gas is used as a gas for inflating the balloon, when the balloon is inflated, the oxygen gas moves through the oxygen gas permeable membrane of the balloon to the blood in the blood passage, and oxygen This is preferred because it allows the delivery of enriched blood. When the balloon is composed of an oxygen gas permeable membrane, the whole balloon may be composed of an oxygen gas permeable membrane, or a part of the balloon may be composed of an oxygen gas permeable membrane. Examples of the oxygen gas permeable membrane include silicon, fluororubber, and polyacetylene-based polymer. As described above, it is preferable that the balloon is formed of an oxygen gas permeable membrane, because blood can be sent out and oxygen can be enriched at the same time. The balloon inflation gas passage may be mounted inside the passage catheter or may be embedded inside the catheter wall. Inflation or deflation of the balloon may be performed by a balloon driving device.As the balloon driving device, for example, the balloon is driven by vibrating or driving a diaphragm connected to a base of a balloon inflation gas passage connected to the balloon. That can perform expansion and contraction. The period of the inflation and deflation of the balloon may be appropriately selected and determined according to the required blood volume.
It is preferable to increase the flow rate by moving the flow at a high speed of 00 Hz to create a flow substantially close to a steady flow.

The blood passage volume changing mechanism has means for sequentially reducing and restoring the volume of the blood passage before or after the suction port. Means for reducing and restoring the volume of these blood passages is not particularly limited, and various means can be used.For example, a balloon is attached to the outside of the catheter, and the balloon is inflated to inflate the inside of the catheter wall. Indented,
Means to reduce the volume of the blood passage, then deflate the balloon and replace the catheter wall, reducing the volume of the blood passage by attaching the balloon inside the catheter and inflating the balloon, then removing the balloon. Means for reducing the volume of the blood passage by returning the volume of the blood passage to the original state may be used. When the balloon is inflated, it is not necessary to close the blood passage, but only to reduce the volume of the blood passage. The cycle of the reduction and restoration of the volume of the blood passage may be appropriately selected and determined according to the required blood volume, similarly to the intra-catheter balloon mechanism.
It is preferable to increase the flow rate by moving the flow at a high speed of 100 Hz to create a flow substantially close to a steady flow. Note that a check valve may be further attached to the blood passage between the check valve and the suction port. This check valve has a function of sending blood in the direction of the discharge port, but does not allow blood to flow in the direction of the suction port. The same check valve can be used. By providing this check valve, it is possible to discharge blood more efficiently. In addition, as described above, even in the case of the blood passage volume variation mechanism, a check valve can be provided at the suction port to make the discharge of blood more efficient.

Next, the second invention of the present application will be described. The blood circulation assist device of the second invention of the present application has a suction port at the distal end of a catheter having a blood passage therein. The distal end of the catheter provided with the suction port has the same meaning as in the first invention of the present application, but the mounting position of the suction port is preferably the distal end. The shape and size of the suction port are not particularly limited as long as the shape and size can be inserted into a target department and suck blood, but the shape is preferably circular or elliptical, and the size is large. Is preferably larger, but may be appropriately selected according to the size of the catheter diameter. Also,
The tip may have a curved shape for better control of the direction. The tip can be softened so as not to damage the tissue, and the diameter of the tip can be reduced.

The blood circulation assist device of the second invention of the present application has a discharge port in a portion within 40 cm from the suction port toward the hand. The position where the discharge port is provided is within a range of 40 cm in the hand direction from the suction port, but is preferably 20 cm.
And particularly preferably within 10 cm. As described above, since the positions of the discharge port and the suction port are short,
Pressure loss can be reduced. The shape and size of the discharge port are not particularly limited as long as the shape and size can suck blood, and may be appropriately selected according to the diameter, thickness, material, and the like of the catheter. The number of discharge ports may be one or two or more. When a plurality of outlets are provided, the outlets may be arranged in the longitudinal direction of the catheter, may be arranged in the outer peripheral direction of the catheter, or may be a combination thereof. The catheter used in the blood circulation assisting apparatus of the second invention of the present application has a blood passage therein, and this blood passage needs to be at least between the suction port and the discharge port. The catheter may be in the form of a tube over the entire length of the hand portion, and a catheter similar to the catheter of the first invention of the present application can be used.

[0014] The blood circulation assisting device of the second invention of the present application has a check valve in the suction port or in the blood passage between the suction port and the discharge port. The check valve provided at the suction port has a function of sucking blood from the suction port but not discharging the blood once sucked through the suction port. Thereby, the blood can be discharged efficiently. The check valve provided between the suction port and the discharge port can pass blood sucked from the suction port provided at the distal end in the direction of the discharge port, but can pass the blood collected in the blood passage toward the suction port. It has a function that does not pass through. As these check valves, those similar to the check valve of the first invention of the present application described above can be used. The check valve may be attached to the suction port or in the blood passage between the suction port and the discharge port, but is preferably closer to the discharge port. Further, the check valve may be attached to one of the suction port or the blood passage between the suction port and the discharge port, or may be attached to both.

The blood delivery means of the blood circulation assist device of the second invention of the present application is the same as the blood delivery means of the first invention of the present application, and the blood passage can be repeatedly closed and pierced almost sequentially before or after the discharge port. A blood passage volume changing mechanism capable of sequentially repeating the reduction and restoration of the volume of the blood passage before or after the in-catheter balloon mechanism or the discharge port on which the balloon is mounted. Note that a check valve may be further attached to the blood passage between the check valve and the discharge port. This check valve has a function of sending blood in the direction of the discharge port, but does not allow blood to flow in the direction of the suction port. The same check valve can be used. By providing this check valve, it is possible to discharge blood more efficiently.

When the blood circulation assisting device of the present invention is percutaneously inserted from a peripheral blood vessel, a hemostatic device can be attached to the catheter so that blood does not flow out of the interface between the catheter and the blood vessel. Examples of the hemostatic device include a hemostatic sheath. In the blood circulation assisting device of the present invention, the catheter portion can be inserted from a peripheral blood vessel. As the peripheral blood vessel into which the catheter portion of the present invention is inserted, it is preferable to select a peripheral blood vessel located at a location close to the skin and having a large diameter, such as a jugular vein, a subclavian vein, a hip artery, an iliac artery, and a cervical artery. Arteries or subclavian veins are most preferred. As described above, since a catheter that can be inserted from a peripheral blood vessel located near the skin is used, blood can be extremely easily delivered. The insertion of the catheter into the peripheral blood vessel may be performed percutaneously, or may be performed by exposing the blood vessel surgically. The insertion of these catheters is preferably performed while seeing through. For this reason, it is preferable that radiopaque properties be imparted to necessary portions of the catheter.

[0017]

According to the blood circulation assisting device having the above-mentioned structure, the blood outlet is inserted percutaneously from a peripheral blood vessel or the like, and the discharge port or the suction port at the distal end is arranged at the target blood discharge section. By means, blood can be sucked in from the suction port and blood can be sent out from the discharge port. Specifically, when the blood delivery means is an intra-catheter balloon mechanism, the blood passage can be substantially closed and pierced sequentially by sequentially repeating the inflation and contraction of the balloon. When the balloon is contracted, the blood passage is depressurized. The blood is sucked into the blood passage from the suction port, and when the balloon is inflated, the pressure of the sucked blood increases due to the expansion of the balloon and is sent out from the blood passage to the discharge port, and the suction and discharge operations are sequentially repeated. Blood can be pumped out. When the blood delivery means is a blood passage volume variation mechanism, the reduction and restoration of the volume of the blood passage are sequentially repeated, so that when the volume of the blood passage is reduced, the blood in the blood passage is reduced in the case of the first invention of the present application. Discharge from the check valve near the distal end of the catheter to the discharge port. In the case of the second invention of this application, blood in the blood passage is discharged from the suction port to the discharge port within a range of 40 cm in the hand direction, and the volume of the blood passage is At the time of restoration, in the case of the first invention of the present application, the blood sucked from the suction port is sent to the blood passage, and in the case of the second invention of the present application, the blood sucked from the suction port at the distal end passes through the check valve. The blood is sent into the passage, and the blood can be sent out by sequentially repeating the sucking and discharging operations.

[0018]

Embodiments of the present invention will be described below with reference to the drawings. The present invention is not limited by these examples. FIG. 1 is a sectional view showing an example of a distal end portion of a catheter in a blood circulation assisting apparatus having a balloon mechanism in a catheter according to the present invention. In the figure, a catheter 1 is a tube made of a polyurethane resin, having an outer diameter of 6 mmφ and an inner diameter of 4 mmφ. The catheter 1 has a discharge port 2 at its tip, and the discharge port 2
A check valve 5 is provided in the blood passage 4 at a position 1 cm proximal from the blood passage 4. Further, a suction port 3 is provided in the catheter wall at a position 10 cm in the hand direction from the discharge port 2, and between the check valve 5 and the suction port 3, 3 cm in the hand direction from the discharge port 2.
A balloon 6 is mounted on the inner wall of the catheter ranging from 8 cm to 8 cm. This balloon is formed of an oxygen gas permeable membrane made of silicon rubber. The inner wall of the catheter 1 has an oxygen gas passage 7 for balloon inflation.
Is extended to the proximal portion, and the balloon can be inflated by blowing oxygen gas into the oxygen gas passage for balloon inflation. In the figure, the balloon 6 is deflated, and the blood passage 4 is penetrated. When the balloon 6 changes from the inflated state to the contracted state as shown in the figure, the pressure in the blood passage 4 becomes negative, and blood is sucked into the blood passage 4 from the suction port 3.

FIG. 2 is a sectional view when the balloon of FIG. 1 is inflated. When the balloon 6 is inflated from the deflated state to substantially close the blood passage with some clearance, the pressure of the blood in the blood passage 4 increases, and the blood is pushed out from the check valve 5 to the discharge port 2. It is. When the balloon 6 is inflated, oxygen enters the blood through the membrane because the balloon is formed of the oxygen gas permeable membrane, and oxygen-enriched blood can be sent out. By repeating the inflation and deflation of the balloon 6 in this manner, the blood passage 4 can be substantially closed and pierced repeatedly. As a result, blood is sucked into the blood passage 4 and blood in the blood passage 4 is discharged. Can be sent out from the exit. It should be noted that the blood passage 4 may be sealed from the suction port 3 to the near side. Furthermore, between the balloon 6 and the suction port 3, the discharge port 2
A check valve which can send out blood in the direction but not allow blood to flow in the direction of the suction port 3 may be provided.
When the catheter portion of this blood circulation assisting device was inserted into the aorta from the hip artery and the distal end of the catheter was inserted into the coronary artery, and the blood was pumped out, the blood could be pumped out very smoothly.

FIG. 3 is a sectional view showing another example of the distal end portion of the catheter 1 in the blood circulation assisting apparatus having the intra-catheter balloon mechanism of the present invention. In the drawing, a discharge port 2 is provided at a distal end of a catheter 1, and a check valve 5 is provided in a blood passage at the distal end. A suction port 3 is provided 10 cm from the discharge port 2 in the hand direction of the catheter 1. The suction port 3 has a check valve structure, and a blood passage 4 at the distal end of the catheter 1.
Is provided on the wall of the catheter between the check valve 5 and the balloon 6. When the balloon 6 is deflated, the inside of the blood passage 4 is reduced in pressure, the check valve constituting the suction port 3 is drawn into the blood passage, and the suction port 3 is opened.
Blood is sucked and filled in the blood passage 4. Next, when the balloon 6 is inflated, the internal pressure of the blood filled in the blood passage 4 increases, and the check valve of the suction port 3 comes into close contact with the wall of the catheter 1 and the suction port 3 closes, so that the check valve 5 is closed. From the discharge port 2. FIG. 4 is a plan view of the distal end portion of the catheter 1 of FIG.

FIG. 5 is a schematic sectional view showing an example of a blood circulation assisting device having a balloon mechanism in a catheter according to the present invention. The distal end of the catheter 1 is similar to that of FIG. A diaphragm device is attached to the base of the gas passage 7 for balloon inflation, and the pressure inside the gas passage for balloon inflation is increased or decreased by vibrating the diaphragm 8 right and left. This diaphragm device is connected to the diaphragm driving device 13, and can drive the diaphragm 8 by moving fluid from the diaphragm driving device 13. As the diaphragm driving device 13, a commonly used diaphragm driving device can be used. The oscillation cycle of the diaphragm was 50 Hz, and the blood discharged from the discharge port 2 was discharged in a substantially steady flow. An oxygen supply device 9 is provided on the side of the gas passage 7 for balloon inflation of the diaphragm 8.
Is connected, and the inside of the balloon inflation gas passage 7 is filled with oxygen. The balloon 6 is formed of an oxygen-permeable membrane. Since oxygen is absorbed into blood through the oxygen-permeable membrane, oxygen in the balloon inflation gas passage 7 decreases with time. Therefore, oxygen is added from the oxygen supply device 9 by the adjustment device (not shown) in an amount corresponding to the decrease in oxygen. Note that the oxygen supply device 9 is preferably provided with a device that stops the supply of oxygen when the supply amount of oxygen increases by a certain amount or more. Thereby, when the balloon 6 and the gas passage 7 for balloon inflation are broken, it is possible to prevent oxygen from being excessively fed into the blood. Further, a mechanism for generating an alarm may be provided instead of or together with the device for stopping the supply of oxygen.

FIG. 6 is a sectional view showing another example of the distal end portion of the catheter in the blood circulation assisting apparatus having the intra-catheter balloon mechanism of the present invention. In the figure, a suction port 14 is provided at the distal end of the catheter, and a check valve 15 is provided near the suction port 14. This check valve 15
The blood sucked from the suction port 14 can pass in the direction of the discharge port 16, but cannot pass in the opposite direction. The discharge port 16 is provided at a position 10 cm from the suction port 14 in the hand direction of the catheter 1.
The position of the discharge port 16 may be between the check valve 15 and the balloon 6. The catheter has a structure in which the proximal portion from the discharge port 16 is sealed, and only the distal end of the catheter has the blood passage 4. When the balloon 6 is deflated, the pressure inside the blood passage 4 is reduced, and blood is sucked from the suction port 14 through the check valve 15 and filled in the blood passage 4. When the balloon 6 is inflated, the pressure inside the blood passage 4 increases, and the blood filled in the blood passage 4 increases.
It is exhaled from 6. Although not shown, if a check valve is further provided between the balloon 6 and the discharge port 16, the blood can be sent out more efficiently. This check valve has the same function as the check valve 15,
It has a function of passing blood in the direction of the discharge port 16 but not passing blood in the direction from the discharge port 16 to the suction port.
When blood was pumped from the heart to the aorta using this blood filling auxiliary device, blood could be pumped extremely efficiently.

FIG. 7 is a sectional view of the distal end of an example of the blood circulation assisting device having the blood passage volume changing mechanism of the present invention. In the figure, a catheter 1 is a tube made of a polyurethane resin, having an outer diameter of 6 mmφ and an inner diameter of 4 mmφ. The catheter 1 has a discharge port 2 at its distal end, and a blood passage 4 at a position 1 cm proximal to the discharge port 2.
Is provided with a check valve 5. Further, a suction port 3 is provided on the catheter wall at a position 10 cm in the hand direction from the discharge port 2, and a blood passage 4 between the check valve 5 and the suction port 3 is provided.
Is provided with a check valve 10, and a balloon 11 is attached to the outer wall of the catheter within a range of 3 cm to 7 cm from the discharge port 2 in the hand direction. And catheter 1
A balloon inflation oxygen gas passage 12 is buried in the wall of the device up to the hand, and the balloon can be inflated by blowing oxygen gas into the balloon inflation oxygen gas passage. In the figure, the balloon 11 is inflated, the volume of the blood passage 4 is small, and the blood in the blood passage 4 has a high pressure, and passes through the check valve 5 to the discharge port 2.
Sent out from. When the balloon 11 changes from the inflated state to the contracted state, the pressure in the blood passage 4 becomes negative,
Blood is drawn into the blood passage 4 from the suction port 3 through the check valve 10. In this way, by repeatedly inflating and deflating the balloon 11, the reduction and restoration of the volume of the blood passage 4 can be repeated. As a result, blood is sucked into the blood passage 4 and blood in the blood passage 4 is removed. It can be sent out from the discharge port. In addition, the blood passage 4 is connected to the suction port 3.
The hand side may be sealed.

[0024]

According to the blood circulation assisting apparatus of the present invention, it is possible to easily send blood to a coronary artery or the like even with a small catheter with a small pressure loss, and to pump blood from the heart to send blood to the aorta. For example, it is possible to efficiently assist blood circulation in various circulatory organs. As a result, heart recovery or load reduction can be sufficiently expected. Therefore, the blood circulation assist device of the present invention is extremely useful in practical use.

[Brief description of the drawings]

FIG. 1 is a cross-sectional view of a distal end of an example of a blood circulation assisting device having a balloon mechanism in a catheter according to the present invention.

FIG. 2 is a cross-sectional view of the distal end of the blood circulation assist device of the present invention shown in FIG. 1 when the balloon is inflated.

FIG. 3 is a cross-sectional view of a distal end portion of another example of the blood circulation assist device having the intra-catheter balloon mechanism of the present invention.

FIG. 4 is a plan view of the blood circulation assist device of the present invention of FIG. 3;

FIG. 5 is a schematic cross-sectional view of one example of a blood circulation assisting device having the intra-catheter balloon mechanism of the present invention.

FIG. 6 is a cross-sectional view of a distal end portion of another example of the blood circulation assisting device having the intra-catheter balloon mechanism of the present invention.

FIG. 7 is a cross-sectional view of a distal end of an example of a blood circulation assisting device having a blood passage volume changing mechanism of the present invention.

[Explanation of symbols]

 Reference Signs List 1 catheter 2 discharge port 3 suction port 4 blood passage 5 check valve 6 balloon 7 balloon inflation oxygen gas passage 8 diaphragm 9 oxygen supply device 10 check valve 11 balloon 12 balloon inflation oxygen gas passage 13 diaphragm driving device 14 suction port 15 Check valve 16 Discharge port

──────────────────────────────────────────────────続 き Continued on front page (58) Field surveyed (Int.Cl. ⁷ , DB name) A61M 1 / 10,25 / 00

Claims (4)

(57) [Claims] 1. A blood circulation assisting apparatus having a catheter having a blood passage therein and blood feeding means, wherein the catheter has a discharge port at a distal end thereof, and is within 20 cm from the discharge port toward a hand. The suction port on the catheter wall
A has a check valve in the blood passage between the discharge port or the discharge port and suction port, said blood feed means sequentially repeated almost closed and through before or after the blood passage inlet Or a blood passage volume changing mechanism capable of sequentially repeating the reduction and restoration of the volume of the blood passage before or after the suction port. A blood circulation assist device characterized by the above-mentioned. 2. A balloon comprising an oxygen gas permeable membrane.
The blood circulation assist device according to claim 1. 3. A blood circulation assisting device having a catheter having a blood passage therein and blood feeding means, wherein the catheter has a suction port at a distal end thereof, and is within 20 cm from the suction port toward a hand. Outlet on the catheter wall
A check valve in the suction port or in a blood passage between the suction port and the discharge port, and the blood feeding means sequentially repeats substantially closing and penetrating the blood passage before or after the discharge port. A balloon mechanism in which a balloon that can be attached to the blood passage is mounted in the blood passage, or a blood passage volume variation mechanism that can sequentially and repeatedly reduce and restore the volume of the blood passage before or after the discharge port. A blood circulation assist device characterized by the above-mentioned. 4. A balloon comprising an oxygen gas permeable membrane.
The blood circulation assisting device according to claim 3.