JP2627660B2 - Methods for improving amino acid absorption in ruminants - Google Patents
Methods for improving amino acid absorption in ruminantsInfo
- Publication number
- JP2627660B2 JP2627660B2 JP1076451A JP7645189A JP2627660B2 JP 2627660 B2 JP2627660 B2 JP 2627660B2 JP 1076451 A JP1076451 A JP 1076451A JP 7645189 A JP7645189 A JP 7645189A JP 2627660 B2 JP2627660 B2 JP 2627660B2
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- ruminants
- methods
- amino acids
- acid absorption
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Description
【発明の詳細な説明】 〔産業上の利用分野〕 本発明は反芻動物のアミノ酸吸収量改善方法に関す
る。The present invention relates to a method for improving the absorption of amino acids in ruminants.
動物の肥育、乳量の増大等を目的として飼料にアミノ
酸を添加し、動物に投与することは知られている。しか
し、牛や羊などの反芻動物の場合、特に肥育期以降のも
のでは，アミノ酸を飼料に添加して投与してもアミノ酸
の血中濃度は上昇しない。これは、投与したアミノ酸が
ルーメン内に存在する多数の微生物により分解され、ア
ミノ酸を吸収する第４胃以降まで到達しないためといわ
れている。It is known that amino acids are added to feed and administered to animals for the purpose of fattening animals, increasing milk yield, and the like. However, in the case of ruminants such as cattle and sheep, especially in the fattening period or later, even if amino acids are added to feed and administered, the blood concentration of amino acids does not increase. It is said that this is because the administered amino acid is decomposed by a large number of microorganisms present in the lumen and does not reach the abomasum and beyond which absorb the amino acid.
そこでルーメン内で微生物分解を受けず、第４胃以降
でアミノ酸吸収させるルーメンバイパス手法として、種
々のコーティングアミノ酸製剤や微生物分解を受けない
アミノ酸誘導体が考案されている。Therefore, various coating amino acid preparations and amino acid derivatives that are not subjected to microbial degradation have been devised as a lumen bypass technique that does not undergo microbial degradation in the rumen and absorbs amino acids after the abomasum.
コーティングアミノ酸製剤は、ルーメン内での微生物
分解を受けにくいが、第４胃以降での溶解性が悪く、結
局アミノ酸が利用されないまま体外へ排泄されてしま
う。又反すうを受けてしまうとコーティング処理が噛み
砕かれてしまいルーメン内で微生物分解を受けてしまう
など投与アミノ酸が十分吸収されない。又、製剤化に手
数がかかるという問題がある。The coated amino acid preparation is less susceptible to microbial degradation in the rumen, but has poor solubility in the abomasum and beyond, resulting in excretion of the amino acid without use. In addition, when subjected to rumination, the coating amino acid is chewed and the administered amino acid is not sufficiently absorbed, such as being subjected to microbial degradation in the lumen. In addition, there is a problem that it takes time to formulate the preparation.
又、アミノ酸誘導体は、従来のアミノ酸と比べて安全
性の保障がないという問題がある。In addition, amino acid derivatives have a problem that their safety is not guaranteed as compared with conventional amino acids.
そこで本発明者らは種々検討した結果、アミノ酸を水
に溶解し、それを反芻動物に投与すると投与したアミノ
酸の血中濃度が大幅に上昇することを見い出した。The present inventors have conducted various studies and found that when an amino acid is dissolved in water and administered to a ruminant, the blood concentration of the administered amino acid is significantly increased.
本発明は上記知見に基づき完成されたものである。即
ち、本発明はアミノ酸の１種又は２種以上を含有する液
体組成物を反芻動物に経口投与することを特徴とする反
芻動物のアミノ酸吸収量改善方法に関する。The present invention has been completed based on the above findings. That is, the present invention relates to a method for improving the absorption of amino acids in ruminants, which comprises orally administering a liquid composition containing one or more amino acids to ruminants.
本発明で使用するアミノ酸は反芻動物が必要とするア
ミノ酸であれば特に制限ないが、必須アミノ酸が好まし
く、例えばメチオニン、リジン、トレオニン、トリプト
ファンなどがあげられる。The amino acid used in the present invention is not particularly limited as long as it is an amino acid required by a ruminant, but an essential amino acid is preferable, and examples thereof include methionine, lysine, threonine and tryptophan.
上記アミノ酸を水又は動物に悪影響を与えないエチルア
ルコールなどの溶媒又は含水溶媒に溶解もしくは懸濁さ
せることにより本発明の液状組成物が得られる。The liquid composition of the present invention can be obtained by dissolving or suspending the amino acid in water, a solvent such as ethyl alcohol that does not adversely affect animals, or a water-containing solvent.
この液状組成物中のアミノ酸の含量は１種当り0.1〜3
0w/v％、好ましくは0.1〜10w/v％、更に好ましくは0.5
〜5w/v％程度が良い。The content of amino acids in this liquid composition is 0.1 to 3 per species.
0 w / v%, preferably 0.1 to 10 w / v%, more preferably 0.5
About 5w / v% is good.
この液状組成物には更に溶解補助剤、分散剤、安定剤を
加えても良い。更に蛋白質原料（粉乳、脱脂粉乳、蛋白
分解物等）、炭水化物（ブドウ糖、庶糖、オリゴ糖、で
んぷん等）、油脂（バター、植物油、魚油等）、ビタミ
ン、ミネラル、クエン酸、エチルアルコール、着色料、
香料を加えても良い。The liquid composition may further contain a solubilizer, a dispersant, and a stabilizer. Furthermore, protein raw materials (milk powder, skim milk powder, protein hydrolyzate, etc.), carbohydrates (glucose, sucrose, oligosaccharides, starch, etc.), fats and oils (butter, vegetable oil, fish oil, etc.), vitamins, minerals, citric acid, ethyl alcohol, coloring agents ,
Flavors may be added.
更に抗生物質等の抗菌性物質、防腐剤、酸化防止剤を加
えて良い。Further, antibacterial substances such as antibiotics, preservatives and antioxidants may be added.
本発明の液状組成物を反芻動物に投与する方法として
は、バケツ、オケなどの広口容器に入れて自由摂取させ
ても良いが、強制的に経口投与した方が好ましい。投与
量はアミノ酸として一種当り1mg/kg体重以上、好ましく
は1mg〜1000mg/kg体重、更に好ましくは10mg〜500mg/kg
体重が良い。投与期間は必要に応じて１回投与又は連続
投与どちらでも良い。As a method of administering the liquid composition of the present invention to a ruminant animal, the composition may be freely taken in a wide-mouthed container such as a bucket or an oke, but it is preferable to forcibly orally administer the composition. The dosage is 1 mg / kg body weight or more as one amino acid per amino acid, preferably 1 mg to 1000 mg / kg body weight, more preferably 10 mg to 500 mg / kg.
Good weight. The administration period may be either single administration or continuous administration as necessary.
（効果） 次に本発明の効果を実験例により証明する。(Effects) Next, the effects of the present invention will be proved by experimental examples.
実験例１緬羊におけるメチオニン、リジン、トレオニン
血中濃度試験方法−１ （対照） 体重約50kgの緬羊に体重kg当りDL−メチオニン、Ｌ−
リジン、Ｌ−トレニオンを各々100mg相当量を所定量の
飼料に混合し、給与した。EXPERIMENTAL EXAMPLE 1 Methionine, Lysine, Threonine Blood Concentration Test Method-1 in Sheep Sheep (Control) DL-methionine, L-
Lysine and L-trenion were each mixed and supplied in a predetermined amount of a feed equivalent to 100 mg.
方法−２（本発明方法）同量のアミノ酸組成物を200ml
の水に溶かし液状にて、強制的に、経口的に飲ませた後
所定量の飼料を給与した。Method-2 (the method of the present invention) 200 ml of the same amount of the amino acid composition
After forcibly orally drinking in a liquid form dissolved in water, a predetermined amount of feed was fed.
２法ともに試験開始前および試験開始後４、８時間目
に採血し血漿中のメチオニン、リジン、トレオニン濃度
を測定しアミノ酸の吸収性を測定した。結果を表１、２
に示す。In both methods, blood was collected before the start of the test and 4 to 8 hours after the start of the test, and the concentrations of methionine, lysine, and threonine in the plasma were measured, and the absorbability of amino acids was measured. Tables 1 and 2 show the results.
Shown in
従って、本発明方法により血中アミノ酸量の増大に伴
う反芻動物の肥育効率の改善、乳量の増大、加齢に伴う
乳量の減少の防止などが期待される。 Therefore, the method of the present invention is expected to improve the fattening efficiency of ruminant animals due to an increase in the amount of amino acids in blood, to increase the amount of milk, and to prevent a decrease in the amount of milk due to aging.
Claims (1)
状組成物を反芻動物に経口投与することを特徴とする反
芻動物のアミノ酸吸収量改善方法。1. A method for improving the amount of amino acids absorbed by ruminants, which comprises orally administering a liquid composition containing one or more amino acids to ruminants.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1076451A JP2627660B2 (en) | 1989-03-30 | 1989-03-30 | Methods for improving amino acid absorption in ruminants |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1076451A JP2627660B2 (en) | 1989-03-30 | 1989-03-30 | Methods for improving amino acid absorption in ruminants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02255047A JPH02255047A (en) | 1990-10-15 |
| JP2627660B2 true JP2627660B2 (en) | 1997-07-09 |
Family
ID=13605514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1076451A Expired - Lifetime JP2627660B2 (en) | 1989-03-30 | 1989-03-30 | Methods for improving amino acid absorption in ruminants |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2627660B2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3888699B2 (en) * | 1993-12-28 | 2007-03-07 | 協和醗酵工業株式会社 | Animal nutritional composition |
| CA2261972C (en) * | 1996-07-26 | 2008-02-12 | Ajinomoto Co., Inc. | Method of breeding high-level lactation dairy cows using rumen-bypassed amino acids |
| JP2010110303A (en) * | 2008-11-10 | 2010-05-20 | Marubeni Nisshin Feed Co Ltd | Substitute milk composition for calf |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5513056A (en) * | 1978-07-14 | 1980-01-29 | Sakio Katsumata | Extraction of aqueous growth accelerating liquid |
-
1989
- 1989-03-30 JP JP1076451A patent/JP2627660B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02255047A (en) | 1990-10-15 |
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