JP2627294B2 - CT device with contrast agent concentration control function - Google Patents
CT device with contrast agent concentration control functionInfo
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- JP2627294B2 JP2627294B2 JP63030074A JP3007488A JP2627294B2 JP 2627294 B2 JP2627294 B2 JP 2627294B2 JP 63030074 A JP63030074 A JP 63030074A JP 3007488 A JP3007488 A JP 3007488A JP 2627294 B2 JP2627294 B2 JP 2627294B2
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- contrast agent
- injection
- injector
- contrast
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- 239000002872 contrast media Substances 0.000 title claims description 46
- 238000002347 injection Methods 0.000 claims description 34
- 239000007924 injection Substances 0.000 claims description 34
- 230000000694 effects Effects 0.000 description 11
- 238000005259 measurement Methods 0.000 description 11
- 238000006243 chemical reaction Methods 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 3
- 238000002591 computed tomography Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- XBDRAUPLGHAFCU-UHFFFAOYSA-N 3-[6-amino-5-(6-ethoxynaphthalen-2-yl)pyridin-3-yl]-n-[2-(dimethylamino)ethyl]benzamide Chemical compound C1=CC2=CC(OCC)=CC=C2C=C1C(C(=NC=1)N)=CC=1C1=CC=CC(C(=O)NCCN(C)C)=C1 XBDRAUPLGHAFCU-UHFFFAOYSA-N 0.000 description 1
- 206010059245 Angiopathy Diseases 0.000 description 1
- 208000003174 Brain Neoplasms Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229940039231 contrast media Drugs 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
Landscapes
- Analysing Materials By The Use Of Radiation (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
【発明の詳細な説明】 〔産業上の利用分野〕 本発明は造影剤濃度調節機能付CT装置に関する。Description: TECHNICAL FIELD The present invention relates to a CT device with a contrast agent density adjusting function.
CT画像を鮮明に得るために、CT装置による撮影前に造
影剤を被検体内に注入するやり方がある。この従来例の
文献には、「CTスキャナ」（215頁参照。コロナ社。昭
和54年度発行。岩井編）がある。In order to obtain a clear CT image, there is a method of injecting a contrast agent into a subject before imaging with a CT device. An example of this conventional document is “CT Scanner” (see page 215, Corona Co., Ltd., published in 1979, edited by Iwai).
この従来例は、造影剤を静脈注射した後にCTスキャン
を行わせる。この従来例によれば脳腫瘍や血管障害など
の病変部の吸収係数を増加させ、明瞭な画像を抽出でき
る。In this conventional example, a CT scan is performed after intravenous injection of a contrast agent. According to this conventional example, a clear image can be extracted by increasing the absorption coefficient of a lesion such as a brain tumor or a vascular disorder.
前記従来例は、造影剤注入とCT装置とが連動しておら
ず、CT装置と造影剤注入との連係に欠ける問題がある。
特に造影剤注入器が普及している現在、造影剤注入器と
CT装置との連係は必要である。従来は、CT装置の操作者
が造影剤注入器の外部コントローラを用いて自己の判断
したタイミングで注入を行わせる例多い。また注入器の
種類によっては造影剤を追加するモードは存在しても、
CT装置との連係は不可能であった。従って、最初に設定
した造影剤の注入条件が最適でないと、造影効果が少な
すぎたり、強すぎてアーチファクトの原因となったり患
者の気分の悪化を招くこともある。造影剤の投入は、そ
の条件及び投入タイミングなどで貴重な知識と感性が必
要であり、経験者の作業によることが多かった。The conventional example has a problem that the contrast agent injection and the CT device are not linked with each other, and the linkage between the CT device and the contrast agent injection is lacking.
In particular, as contrast media injectors are widely used,
Coordination with the CT device is necessary. Conventionally, there are many cases in which an operator of a CT apparatus performs injection at a timing determined by the operator using an external controller of a contrast agent injector. Also, depending on the type of injector, there is a mode to add a contrast agent,
Coordination with the CT device was not possible. Therefore, if the initially set contrast medium injection conditions are not optimal, the contrast effect may be too small or too strong, causing artifacts or deteriorating the patient's mood. The introduction of the contrast agent requires valuable knowledge and sensitivity in terms of the conditions and the timing of the injection, and often requires the work of an experienced person.
本発明の目的は、経験者の知識と感性に頼ることなく
適格な造影剤投入を自動的に可能にしたCT装置を提供す
ることにある。SUMMARY OF THE INVENTION An object of the present invention is to provide a CT apparatus which can automatically supply a suitable contrast agent without relying on the knowledge and sensitivity of an experienced person.
本発明は、Ｘ線CTと造影剤注入器の他に、基準個所で
の基準CT値と測定CT値との大小比較を行う手段と、この
比較結果で注入器の制御を行う制御手段とを設けた。The present invention includes, in addition to the X-ray CT and the contrast agent injector, means for comparing the magnitude of a reference CT value and a measured CT value at a reference location, and control means for controlling the injector based on the comparison result. Provided.
本発明では、制御系によって造影剤注入を制御でき
る。特に、基準CT値と計測CT値をみて造影剤投入量の大
小を判断し、次の造影剤投入量の決定に寄与できる。即
ち、造影剤注入直後の画像CT値を読みとり、被検体の個
人差による造影効果を常にチェックする。造影効果が少
ない場合は、制御系を通じて自動的に造影剤を追加注入
する。また、追加注入量が完全に注入される前に期待し
た造影効果が出た場合は注入を停止させる。これによ
り、コントラストが強すぎることによるアーチファクト
の発生防止、被検体への適正な造影剤の注入の確保、造
影剤投入操作の簡便化を達成する。In the present invention, the contrast agent injection can be controlled by the control system. In particular, it is possible to determine the magnitude of the contrast medium supply amount by referring to the reference CT value and the measured CT value, and to contribute to the determination of the next contrast medium supply amount. That is, the image CT value immediately after the injection of the contrast agent is read, and the contrast effect due to the individual difference of the subject is always checked. If the contrast effect is small, the contrast agent is automatically injected through the control system. If the expected contrast effect is obtained before the additional injection amount is completely injected, the injection is stopped. As a result, it is possible to prevent the occurrence of artifacts due to the contrast being too strong, to ensure the proper injection of the contrast agent into the subject, and to simplify the operation of introducing the contrast agent.
第１図は本発明の実施例図を示す。第２図は動作タイ
ムチャートである。FIG. 1 shows an embodiment of the present invention. FIG. 2 is an operation time chart.
CPU1は、CT装置本体（図示せず）の制御を行う。CT装
置本体とはCT装置の機械系及び駆動制御系との両者を含
む。CT計測データの収集及び処理の系は含まない。The CPU 1 controls a CT device main body (not shown). The CT device main body includes both a mechanical system and a drive control system of the CT device. The system for collecting and processing CT measurement data is not included.
計測インターフェース２及び演算（各種前処理、画像
再構成処理）器３は、計測データを取込んでCT画像を得
る。このCT画像は、磁気ディスク７にインターフェース
６を介して一時的に格納される。この格納CT像又は演算
器３で得られたCT像は画像表示回路４を介して断層像と
して表示される。The measurement interface 2 and the calculation (various pre-processing, image reconstruction processing) unit 3 take in the measurement data to obtain a CT image. This CT image is temporarily stored on the magnetic disk 7 via the interface 6. The stored CT image or the CT image obtained by the calculator 3 is displayed as a tomographic image via the image display circuit 4.
更に重要なことは、CRT5は、計測断層像の表示以外
に、インジェクタ注入のための比較対象のCT値を表示す
る。比較対象のCT値とは、被検体の基準個所の指定CT値
と、当該基準個所から得られる測定CT値とを云う。指定
CT値とは、外部操作ユニット（キーボードを含む）８か
ら与えられる希望CT値であり、測定CT値とは演算器３か
ら得られた実際に計測された実測CT値である。当然のこ
とながら、CT値とは、被検体の組織体へのコード変換前
の値であり、断層像とは、このCT値を被検体の組織体へ
のコード変換した変換後のデータである。コード変換と
は、皮膚については何階調表示するとか、骨については
何階調表示するとかのCT値→階調変換を云う。More importantly, the CRT 5 displays a CT value to be compared for injector injection, in addition to displaying a measured tomographic image. The CT value to be compared refers to a designated CT value of a reference point of the subject and a measured CT value obtained from the reference point. Designation
The CT value is a desired CT value provided from an external operation unit (including a keyboard) 8, and the measured CT value is an actually measured CT value obtained from the computing unit 3 and actually measured. As a matter of course, the CT value is a value before code conversion into the tissue of the subject, and the tomographic image is data after the code conversion of the CT value into the tissue of the subject. . The code conversion means a CT value → gradation conversion such as how many gradations are displayed for the skin and how many gradations are displayed for the bone.
逆に演算器３は、２つのCT値を出力する機能を持つ。 Conversely, the arithmetic unit 3 has a function of outputting two CT values.
造影剤注入器（インジェクタ）10は、インターフェー
ス９を介して造影剤注入指令（注入量を含めた）を受取
り、造影剤の自動投入を行う。この指令はCPU1が行う。The contrast medium injector (injector) 10 receives a contrast medium injection command (including the injection amount) via the interface 9 and automatically supplies the contrast medium. This command is issued by the CPU 1.
尚、伝送路20は共通バスであり、この共通バスを介し
て各種信号の伝送が行われる。The transmission path 20 is a common bus, and various signals are transmitted via the common bus.
第２図の動作タイムチャートを利用して全体動作を説
明しよう。The overall operation will be described with reference to the operation time chart of FIG.
先ず、本計測を開始する前にCTはCPU1の指示のもとに
CT計測を行い、画像の再構成を行い、予備CT値を得る。
そしてCT値をチェックしたい領域（ROI）を設定し、ROI
領域のCT値をCRT5上に表示させ、その表示内容をみて操
作員は操作系８を介して目標とする基準CT値を設定す
る。First, before starting the main measurement, CT
Perform CT measurement, reconstruct images, and obtain preliminary CT values.
Then, set the area (ROI) where you want to check the CT value,
The CT value of the area is displayed on the CRT 5, and the operator sets a target reference CT value via the operation system 8 while viewing the displayed contents.
この基準CT値の設定後に、第２図の動作タイムチャー
トの動作に入る。先ず、計測スタンバイ期間が設定され
る。この期間内で、何回かに分けてCTスキャンが行われ
る。図では、ｎ回のCTスキャンを行わせた。ここで、CT
スキャンとは、１つの断層像を得るために、被検体の回
りをまわりながら、Ｘ線を被検体に曝射させることであ
る。各回のスキャン毎にCT断層像を得る。１回のスキャ
ンによる計測データから１つの断層像を得るための処理
時間は、計測終了と同時か又は数秒以内である。従っ
て、図に示すように第１回のスキャンによるCT断層像＃
１は、２回目のスキャン中には表示できる。After setting the reference CT value, the operation in the operation time chart of FIG. 2 is started. First, a measurement standby period is set. During this period, CT scans are performed several times. In the figure, n CT scans were performed. Where CT
The scanning is to irradiate the subject with X-rays while rotating around the subject to obtain one tomographic image. A CT tomogram is obtained for each scan. The processing time for obtaining one tomographic image from measurement data by one scan is the same as the end of measurement or within several seconds. Therefore, as shown in the figure, the CT tomographic image # by the first scan
1 can be displayed during the second scan.
一方、注入器10を制御する期間は、実際にＸ線が出さ
れて計測するスキャン期間に限る。計測スタンバイ期間
中のみ注入器10は動作可能であり、従って、スタンバイ
期間中は注入器９は何時でもインターフェース９の指示
のもとに動作可能状態で待機している。On the other hand, the period during which the injector 10 is controlled is limited to the scan period in which X-rays are actually emitted and measured. The injector 10 is operable only during the measurement standby period. Therefore, during the standby period, the injector 9 is in an operable state at any time under the instruction of the interface 9.
第２図では、２つの動作の例を示した。動作１は、造
影剤注入効果がゆるやかに現われる例であり、例えば肝
臓のCT断層像の例である。動作２は、造影剤注入効果が
早く現われる例であり、血管や腎臓の例である。FIG. 2 shows two examples of the operation. Operation 1 is an example in which the contrast medium injection effect appears slowly, and is, for example, an example of a CT tomographic image of the liver. Operation 2 is an example in which the contrast medium injection effect appears earlier, and is an example of a blood vessel or a kidney.
動作１では、３回のスキャン期間を含めて注入器10の
連続投入指令を与えている。第１回目と第２回目のスキ
ャンによるCT断層像を得た際に、基準CT値と測定CT値と
をCRT5上に表示させて、両者の大小関係を観察（×印で
大小比較を行う）し、基準CT値が大きいならば、投入指
令を継続させて出す。第３回目のスキャンの結果、ROI
領域での測定CT値が大きくなったが故に、注入器10への
注入指令は停止させる。第４回目，第５回のスキャンに
よっても図では測定CT値が基準CT値よりも大であること
から、注入器10への注入指令は出さない。In the operation 1, a continuous injection command of the injector 10 is given including three scanning periods. When CT tomographic images obtained by the first and second scans are obtained, the reference CT value and the measured CT value are displayed on the CRT5, and the magnitude relationship between them is observed (the magnitude is compared by crosses). If the reference CT value is large, the injection command is continued and issued. ROI from third scan
The injection command to the injector 10 is stopped because the measured CT value in the region has increased. Even in the fourth and fifth scans, since the measured CT value is larger than the reference CT value in the figure, an injection command to the injector 10 is not issued.
心臓や、血管を観測する時は造影効果がすばやく現わ
れ、又すぐに流れ出てしまい又、造影剤がこすぎるとア
ーチファクトが発生し微妙な造影剤コントロールが必要
となる。そのため、動作２では、注入器10の注入は、ス
キャン期間中のみに限らせ、連続注入はさせないことと
している。即ち、第１回目，第２回目のスキャンに同期
して注入器10へ注入指令を与える。この第２回目のスキ
ャンによるCT断層像を得、且つROI領域での測定CT値を
得、この測定CT値と基準CT値とを併せて表示し、その大
小関係をみる。図では未だ基準CT値に達していない。し
かし、その両CT値との偏差をみるに、次回の第３回目の
スキャン時には基準CT値を越えていると考えられること
から、第３回目の造影剤の投入は行わない。そして第３
回目のスキャン後のCT値との間で比較を行い、基準CT値
よりも大きい測定CTが得られたことがわかる。以下、同
様に繰返す。通常血管系では造影注入後３秒位で造影効
果が現われ、その効果は２〜４秒以内である。よって計
測シーケンスを３〜４秒周期で行いかつ注入造影剤の量
を最適化するとたえず血管内の造影剤結果をほぼ一定に
保つ事も可能となる。When observing the heart and blood vessels, the contrast effect appears quickly and flows out immediately, and when the contrast agent is too much, an artifact is generated and delicate contrast agent control is required. Therefore, in the operation 2, the injection of the injector 10 is limited only during the scan period, and the continuous injection is not performed. That is, an injection command is given to the injector 10 in synchronization with the first and second scans. A CT tomographic image obtained by the second scan is obtained, and a measured CT value in the ROI region is obtained. The measured CT value and the reference CT value are displayed together, and the magnitude relationship is observed. In the figure, the reference CT value has not yet been reached. However, the deviation from both CT values is considered to exceed the reference CT value at the next third scan, so the third contrast medium injection is not performed. And the third
Comparison with the CT value after the second scan shows that a measured CT larger than the reference CT value was obtained. Hereinafter, the same is repeated. Normally, in the vascular system, a contrast effect appears about 3 seconds after the contrast injection, and the effect is within 2 to 4 seconds. Therefore, when the measurement sequence is performed at a cycle of 3 to 4 seconds and the amount of the injected contrast agent is optimized, the result of the contrast agent in the blood vessel can be kept almost constant.
尚、投入器10の投入指令から実際の投入動作に入るま
での期間は迅速であり、投入指令が与えられると直ちに
投入器10は応動し、投入動作を行うものとした。The period from the input command of the input device 10 to the start of the actual input operation is quick, and the input device 10 immediately responds to the input command to perform the input operation.
以上の動作1,2から明らかなように、基準CT値が測定C
T値よりも大きければ、造影剤の投入が直ちになされ、
逆に測定CT値が大きければ、造影剤の投入は停止する。
これによって、適正な造影剤の投入が行われ、この造影
剤による造影効果を伴ったCT断層像を得る。As is clear from the above operations 1 and 2, the reference CT value is measured C
If it is larger than the T value, the contrast agent is immediately injected,
Conversely, if the measured CT value is large, the injection of the contrast agent stops.
As a result, an appropriate contrast agent is supplied, and a CT tomographic image with a contrast effect by the contrast agent is obtained.
尚、造影剤の注入では、時間当りの注入量を少なくし
て長い時間かけて注入を行う場合と、時間当りの注入量
を少なくして短い期間に何回かにわけて注入する場合
と、がある。動作１は、前者に適し、動作２は後者に適
する。In contrast, in the injection of the contrast agent, the injection amount per time is reduced and the injection is performed over a long time, and the injection amount per time is reduced and the injection is performed several times in a short period, There is. Operation 1 is suitable for the former, and operation 2 is suitable for the latter.
尚、以上の実施例では、CRTに基準CT値と測定CT値と
の両者を表示し、操作者の観察により投入器の動作指定
を与えることとした。しかし、CRTに表示させずに、演
算器３内で自動的に比較し、投入必要ならば、自動的に
投入指令を与えるようにしてもよい。これは、ソフトウ
エアによって解決できる。また、CPU1でこの自動判定及
び投入指令を与えてもよい。これらの自動判定、自動指
令に際しては、ROI領域をアドレスとして指定してお
き、測定CT値の中でROI領域のCT値を読出して、判定を
行わせる。In the above embodiment, both the reference CT value and the measured CT value are displayed on the CRT, and the operation of the thrower is specified by the operator's observation. However, the comparison may be automatically performed in the computing unit 3 without displaying on the CRT, and if necessary, an input command may be automatically given. This can be solved by software. Further, the CPU 1 may give this automatic determination and injection command. At the time of these automatic determinations and automatic instructions, the ROI area is designated as an address, and the CT value of the ROI area is read out of the measured CT values to make a determination.
更に投入器の動作は、CT値の条件によっては動作パタ
ーンを変更する様にできるため、初めに動作２のパター
ンで動作させ、以後は動作１のパターンで動作させるよ
うにすることもできる。体内の測定CT値によっては又造
影剤が注入される事もできるし、一度基準CT値を越えた
ら注入器を完全に停止する事も可能である。これら色々
な要求に対応するために計測モードによっては動作パタ
ーンを幾つか設定しておき（プロトコル化）、適宜いず
れかを選択させるようにすればよい。Further, since the operation of the thrower can be changed in the operation pattern depending on the condition of the CT value, it can be operated first in the operation 2 pattern and thereafter in the operation 1 pattern. Depending on the measured CT value in the body, a contrast agent can be injected, or the injector can be stopped completely once the reference CT value is exceeded. In order to respond to these various demands, some operation patterns may be set (protocolized) depending on the measurement mode, and any one of them may be selected as appropriate.
更に、基準CT値を固定としたが、時間の推移に従って
基準CT値を曲線化させておくこともできる。第３図はそ
の一例を示す。Further, the reference CT value is fixed, but the reference CT value may be curved in accordance with the transition of time. FIG. 3 shows an example.
本発明によれば、Ｘ線CTに連動して造影剤注入器を動
作させることとしたため、基準CT値と測定CT値との大小
関係によって注入器による造影剤注入を自動的に投入で
きることとなった。これによって、造影剤の適正な注
入、アーチファクトの減少、操作員の負担の軽減をはか
ることができた。According to the present invention, since the contrast agent injector is operated in conjunction with the X-ray CT, the contrast agent injection by the injector can be automatically injected based on the magnitude relationship between the reference CT value and the measured CT value. Was. As a result, it was possible to properly inject the contrast agent, reduce artifacts, and reduce the burden on the operator.
第１図は本発明の実施例図、第２図はその動作タイムチ
ャート、第３図は基準CT値例図である。 １……CPU（プロセッサ）、３……演算器、10……造影
剤投入器（インジェクタ）。FIG. 1 is an embodiment diagram of the present invention, FIG. 2 is an operation time chart thereof, and FIG. 3 is an example diagram of reference CT values. 1 ... CPU (processor), 3 ... Calculator, 10 ... Contrast agent injector (injector).
Claims (1)
よる基準箇所での測定CT値と該基準個所での基準CT値と
の大小を比較する手段と、比較の結果、基準CT値が大き
い場合に上記造影剤注入器を制御して造影剤注入の制御
を行い、基準CT値が小さい場合には上記造影剤注入器に
よる造影剤注入を停止させる制御を行う制御手段と、よ
り成る造影剤濃度調節機能付CT装置。1. An X-ray CT, a contrast agent injector, and means for comparing the magnitude of a measured CT value at a reference location by the X-ray CT with a reference CT value at the reference location; When the reference CT value is large, controls the contrast agent injector to control the contrast agent injection, and when the reference CT value is small, the control means performs control to stop the contrast agent injection by the contrast agent injector, and , A CT device with contrast agent concentration control function.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63030074A JP2627294B2 (en) | 1988-02-13 | 1988-02-13 | CT device with contrast agent concentration control function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63030074A JP2627294B2 (en) | 1988-02-13 | 1988-02-13 | CT device with contrast agent concentration control function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01207038A JPH01207038A (en) | 1989-08-21 |
| JP2627294B2 true JP2627294B2 (en) | 1997-07-02 |
Family
ID=12293652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63030074A Expired - Fee Related JP2627294B2 (en) | 1988-02-13 | 1988-02-13 | CT device with contrast agent concentration control function |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2627294B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11342125A (en) * | 1998-03-30 | 1999-12-14 | Toshiba Corp | X-ray ct device |
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Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62216199A (en) * | 1986-03-18 | 1987-09-22 | Toshiba Corp | X-ray ct device |
-
1988
- 1988-02-13 JP JP63030074A patent/JP2627294B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11342125A (en) * | 1998-03-30 | 1999-12-14 | Toshiba Corp | X-ray ct device |
| JP4594459B2 (en) * | 1998-03-30 | 2010-12-08 | 株式会社東芝 | X-ray CT system |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01207038A (en) | 1989-08-21 |
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