JP2622056B2 - Spray liquid container - Google Patents

Abstract

The vessel (1) for perfusion liquids of the type which is closed at one extremity (4) and having a filling orifice (6) at the other (5) with a zone (8) for the insertion of a syringe or abstraction needle of the catheter supply tube, the vessel (1) being characterized by having incorporated therein integrally and inviolably a microfilter (7) for wet filtration preventing the passage of air under atmospheric pressure and permitting its correct functioning without dismantling the sterilized assembly. <IMAGE>

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a spray liquid (perfusion liquid).
ds) for improvement of containers.

[0002]

2. Description of the Related Art Spray liquid containers are widely used to contain various fluids that are to be sprayed or poured onto the human body.
A particular requirement of such a container is that the fluid be contained in the container under sterile conditions that must be maintained until the moment of using the fluid in clinical surgery. It is customary today to sterilize containers that already contain fluids used for therapeutic purposes. This fluid must be able to withstand the procedure. Or, conversely, the container is sterilized before filling with the fluid, and the sterilized container is filled. In this case, the sterilization state required for the fluid to be filled into the container,
And the container itself must be able to maintain its sterile condition.

[0003]

The present invention does not require (or does not have such a requirement for) a sterile enclosure as described above to sterilize the liquid contained in the container, a significant advantage over existing containers. It is an object of the present invention to provide an improved container for spray liquid having the following. The invention also provides a container for the spray liquid, wherein the sterilization is maintained until the moment of use and which is equipped with an automatic control device for executing the procedure correctly.

[0004]

Accordingly, a container for a spray liquid according to the present invention for achieving the above object has, in particular, a filling tube for filling the container. The fill tube has a porous sterile membrane filter with pores of approximately 0.20 to 0.25 microns. The filter bore is integrally and inviolably connected to the filling tube. The holes allow a sterilization action with the filling of the container, generate considerable capillary forces from the micro-channels and allow the airflow to be shut off unless subjected to pressures of the order of 3 bar, with a maximum of 0,0.
Preferably it is 22 microns. This phenomenon proves the correct operation of the filter and consequently completes it.
This controls the exact operation of the filter. This is because the pressure is required to overcome this tension and allow air to enter the container due to surface tension in the microchannels of the filter. Therefore, in order to test the effectiveness of the filter, after filling the container, air pressure equivalent to the surface tension generated by the filter is applied, and it is observed that no bubbles are generated in the container at that point. I just need. This bubble point observation, which can be measured by air pressure due to the resistance of the filter, is a simple way to determine the integrity of the filter itself.

More specifically, a spray liquid container according to the invention is closed at one end and has an opening for filling the container at the other end and inserts a withdrawal needle of an injector or a catheter supply tube. Integrated and non-intrusively provided with a wet-type micro filter which is composed of a flat body having a region for performing It is characterized by. The sterilizing filter is composed of two plates having a circular groove or a curved groove which are connected to each other with the grooves facing each other, one plate having a filling tube, and the other plate having the filling tube. It is preferred to have a connecting member bonded or welded to the tube united into the container. A tubular inlet parallel to the united tube, the tubular inlet having a closure member and a thin septum for introducing a withdrawal needle for a syringe or catheter supply at a distance therefrom; It is preferred to have In the container of the present invention, the tubular inlet for discharging the fluid preferably has a manually openable closing member at its upper end. The container of the invention has a removable element having two tubular bodies at the upper end, one of said tubular bodies receiving a tube for filling said container and the other of said tubular bodies for feeding a catheter. It is preferred to have a septum that can be pierced by a withdrawal needle and a closure tab that can be manually operated. Hereinafter, preferred examples are given,
The present invention will be described in more detail with reference to the drawings.

[0006]

BRIEF DESCRIPTION OF THE DRAWINGS As can be seen from the drawings, the present invention comprises a container 1, which is formed of a generally flat, clinically compatible synthetic material. The front face 2 and the back face 3 are each generally planar with upper and lower areas 4,5, and the upper and lower areas 4,5 have semi-circular or similar ridges to give the area adequate rigidity and strength. Or a projection is formed. The upper region 5 integrally houses therein a filling tube 6 provided with a sterilizing filter 7 thereon, and the sterilizing filter 7 forms a part of a non-removable non-invasive system. The sterile filter 7 has 0.20 to 0.25 micron pores. The holes serve to fill the spray liquid through the filling tube 6, and the passage of the fluid passing through the sterilizing filter 7 exhibits a sterilizing effect.
Preferably does not exceed 0.22 microns in order to act as a stop or lid against the ingress of air. This microporous filter does not allow air to pass unless a pressure of up to about 3 bar is applied. This feature also effectively controls the sterilization characteristics of the sterilization filter 7 described below.

[0007] The container has an access pipe 8 parallel to the filling pipe 6.
And the access tube 8 incorporates a thin septum 9 that can be pierced by the needle of the spray catheter supply tube. At the top of the orifice of the access tube 8, a stopper or plug 10 having a tab 11 is fixed. The stopper serves to facilitate its opening and to secure its lid until use. FIG. 3 shows a sterile membrane filter 7 having two flat elements 12, 13 joined by welding or pressing. The element 13 has a filling tube 14 as part of it, and the element 12 extends through a tubular connection 15 which is connected to the upper end of the filling tube 6 by welding or gluing.

[0008]

According to the present invention having the above structure, the container 1 can be filled without sterilizing the surroundings, simplifying the operation, increasing safety and reducing costs. Moreover, due to the nature of the sterile filter, sterilization during and after filling prevents the invasion of particles that do not exceed the dimensions intended for the sterilizing effect, as described above, while effectively blocking the entry of external air and filtering. Enable monitoring of effects.

[Brief description of the drawings]

FIG. 1 is a front view of a container in a vertical position according to the present invention.

FIG. 2 is a plan view of the container of FIG.

FIG. 3 is a detailed vertical sectional view of a filling tube assembly incorporating a filter according to the present invention.

FIG. 4 is a transverse sectional view taken along the line IV-IV in FIG. 3;

FIG. 5 is a sectional view taken along the line VV of FIG. 3;

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 ... Container 2 ... Front surface 3 ... Back surface 4 ... Upper region 5 ... Lower region 6 ... Filling tube 7 ... Sterilization filter 8 ... Access tube 9 ... Partition wall 10 ... Stopper or plug 11 ... Tab 12, 13 ... Flat element 14 ... Filling tube 15 ... tubular connection

Claims (6)

(57) [Claims] 1. A flat body closed at one end and having an opening for filling a container at the other end and having an area for inserting a withdrawal needle of an injector or a catheter supply tube, A container for containing a spray liquid, which is integrally and inviolably provided with a wet microfilter that prevents the passage of air under atmospheric pressure and performs an accurate sterilization function without removing a sterilization assembly. . 2. The container of claim 1, wherein said microfilter is a porous filter having pores of about 0.20 to 0.25 microns, preferably up to 0.22 microns. 3. The sterilizing filter comprises two plates having a circular groove or a curved groove which are connected to each other with the grooves facing each other, one of which has a filling tube, and the other has a filling tube. 3. The container of claim 2 wherein said plate has a connecting member bonded or welded to a tube integrated into said container. 4. A tubular inlet parallel to said united tube, said tubular inlet having a closure member and introducing a withdrawal needle of an injector or catheter supply tube at a predetermined distance therefrom. The container of claim 1 having a thin septum for forming. 5. The container of claim 4, wherein said tubular inlet for discharging fluid has a manually openable closure at its upper end. 6. A removable element having at its upper end two tubular bodies, one of said tubular bodies receiving a tube for filling said container and the other of said tubular bodies being a catheter feed tube. 6. The container of claim 5 having a septum piercable by the extraction needle of claim 1 and a lid operable manually.