JP2614484B2 - Indoor air freshener with the effect of raising awareness level - Google Patents
Indoor air freshener with the effect of raising awareness levelInfo
- Publication number
- JP2614484B2 JP2614484B2 JP63083714A JP8371488A JP2614484B2 JP 2614484 B2 JP2614484 B2 JP 2614484B2 JP 63083714 A JP63083714 A JP 63083714A JP 8371488 A JP8371488 A JP 8371488A JP 2614484 B2 JP2614484 B2 JP 2614484B2
- Authority
- JP
- Japan
- Prior art keywords
- lemon
- effect
- indoor air
- air freshener
- raising
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Detergent Compositions (AREA)
- Fats And Perfumes (AREA)
Description
【発明の詳細な説明】 ［産業上の利用分野］ 本発明は、ヒトまたは動物の意識水準を高揚させる、
減圧蒸留により、気圧0.08mmHgの下で、100℃以前に留
出する部分を除いたレモン油分画部を吸入させることに
より、ヒトまたは動物の意識水準を高揚させる効果をも
つ室内用芳香剤に関するものである。DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention is to raise the level of human or animal consciousness,
An indoor air freshener that has the effect of raising the level of consciousness of humans or animals by inhaling the lemon oil fraction excluding the portion distilling before 100 ° C under reduced pressure distillation under the pressure of 0.08 mmHg. It is.
［従来の技術］ 従来から、香料などの芳香物質を吸入させることによ
り心身のコントロールを行う、いわゆるアロマテラピー
（芳香療法）という治療方法が知られている。このアロ
マテラピーの中で用いられてきた香料は古来からの伝承
をもとにした天然精油が中心であり、本発明で問題とし
ている「意識水準を高める効果」に関しては、はっか、
ユーカリレモン、ベルベナ、シトロネラ、カヤプテ、サ
ルビア、タイム、クローブ、ローズマリー、ヒソップ、
ベージル等の精油が効果が高いとされている（奥田 治
『アロマテラピー展望』香料;No.140（1983）pp.19−2
6） またP.Rovestiらの研究グループは、レモン、オレン
ジ、ベルベナ、シトロネラ、イランイラン等の単品精油
あるいはサンダルウッド、パッチュリー、ジャスミン、
クローブを基本とした混合物をエアゾールを用いて心理
的抑圧に悩む神経症患者に吸入投与したところ興奮剤を
あたえた時のような効果が得られたとしている。（S.P.
C Aug 475−478 1973） しかしながら、これらの効果は、主観的かつ定性的な
もので、有効性の点で必ずしも満足し得ないものであ
る。また上記の精油は、強い香りを持つものが多く、調
香により調合香料を作成する場合に全体の香りに影響を
与えてしまうことから、香りの強度及び嗜好性と効果発
現の有効量とのバランスについても必ずしも満足しえな
いものであった。上記の効果精油の中で、レモン精油
は、柑橘系の精油の中で最も重要な香料であり、日本の
消費者についての嗜好性も高く、製品香料に汎用される
ものであるが、特有のシトラス香の強度が非常につよい
ものであった。[Related Art] Conventionally, a treatment method called aromatherapy (aroma therapy) for controlling the mind and body by inhaling an aromatic substance such as a fragrance has been known. The fragrances used in this aromatherapy are mainly natural essential oils based on ancient traditions, and the "effect of raising the level of consciousness" which is a problem in the present invention is,
Eucalyptus lemon, verbena, citronella, kayapte, salvia, thyme, clove, rosemary, hyssop,
Essential oils such as basil are said to be highly effective (Osamu Okuda, Aromatherapy Outlook, fragrance; No. 140 (1983) pp. 19-2)
6) P.Rovesti et al.'S research group also included single essential oils such as lemon, orange, verbena, citronella, ylang-ylang, sandalwood, patchouli, jasmine,
The inhalation administration of a clove-based mixture to a neurotic patient suffering from psychological depression using an aerosol provided the effect as if a stimulant was given. (SP
C Aug 475-478 1973) However, these effects are subjective and qualitative and are not always satisfactory in terms of effectiveness. In addition, the above-mentioned essential oils often have a strong scent and affect the entire scent when a compounded fragrance is prepared by scenting. The balance was not always satisfactory. Among the above essential oils, lemon essential oil is the most important fragrance among citrus essential oils, has high palatability for Japanese consumers, and is widely used in product fragrances. The strength of the citrus scent was very strong.
［発明が解決しようとする課題］ 本発明者は上記事情に鑑み、香りの強度が比較的緩和
であり、真に意識水準を高揚させる効果に優れたレモン
精油を得るべく鋭意研究を重ねた結果、0.08mmHgの減圧
下で行う蒸留により、100℃以前に流出する部分を除い
たレモン分画部が、レモンの特有香がかなり微弱になっ
ているにもかかわらず、吸入により強力な意識水準を高
揚させる効果を有するという全く新規な事実を見出し、
この知見に基づいて本発明を完成するに至った。[Problems to be Solved by the Invention] In view of the above circumstances, the present inventors have conducted intensive studies to obtain a lemon essential oil having a relatively moderate fragrance intensity and an excellent effect of truly raising the level of consciousness. Due to distillation performed under reduced pressure of 0.08 mmHg, the lemon fraction except for the part flowing out before 100 ° C has a strong level of consciousness by inhalation despite the fact that the peculiar aroma of lemon has been considerably weakened. Finding a completely new fact that it has an uplifting effect,
Based on this finding, the present invention has been completed.
［課題を解決するための手段］ すなわち本発明は、減圧蒸留により、気圧0.08mmHgの
下で蒸留分画し、100℃以前に留出する部分を除いたレ
モン油分画部（以下、“レモン活性分画部”と略す。）
を有効成分として配合したことを特徴とするヒトまたは
動物の意識水準を高揚させる効果をもつ室内用芳香剤で
ある。[Means for Solving the Problems] That is, the present invention relates to a lemon oil fractionation section (hereinafter, referred to as “lemon activity”) which is fractionated by distillation under reduced pressure at a pressure of 0.08 mmHg and excluding a portion distilled off before 100 ° C. Fractionation unit.)
Is an indoor air freshener having an effect of raising the level of consciousness of humans or animals, characterized by containing as an active ingredient.
ここで言う意識水準を高揚させる効果とは、ヒトまた
は動物が日常生活で経験する眠け、疲労感惰気などの意
識水準の低下による生理心理的状態から開放し、気分を
爽快にするとともに精神活動を活発化させる効果を指す
ものである。The effect of raising the level of consciousness referred to here is to relieve the physio-psychological state of humans or animals from falling consciousness such as sleepiness, fatigue and inertia that they experience in their daily lives, refresh their mood, and excite their spirits. It refers to the effect of stimulating activities.
また、本発明でいう室内用芳香剤とは、“レモン活性
分画部”が有効量吸入され、嗅覚受容体を刺激もしくは
経気道的に体内に吸収されることにより効果が発現する
ものを指し、室内芳香剤などのフレグランス製品であ
る。In addition, the indoor air freshener referred to in the present invention refers to a substance which exerts its effect by inhaling an effective amount of “lemon active fraction” and stimulating the olfactory receptor or absorbing it into the body through the respiratory tract. And fragrance products such as indoor air fresheners.
以下本発明について詳しく説明する。 Hereinafter, the present invention will be described in detail.
本発明における“レモン活性分画部”は、公知の物質
であり、レモン油を気圧0.08mmHgの下で蒸留分画し、10
0℃以前に留出する部分を除いたレモン油分画部で、レ
モン精油の高沸点成分の混合物である。The “lemon active fractionation part” in the present invention is a known substance, and is obtained by distilling and fractionating lemon oil under a pressure of 0.08 mmHg.
It is a mixture of high-boiling components of lemon essential oil in the lemon oil fractionation section excluding the portion distilled off before 0 ° C.
レモン油分画部については、標準商業品種の、Lemon
Naardenized Ｓ oil（クエスト社）の分画部が本発
明に用いられるが、米国産、欧州産等全てのレモン油の
どのような成分組成を持つものの分画部でも用いること
が出来る。For the Lemon Oil Fraction, the standard commercial variety Lemon
The fractionation part of Naardenized S oil (Quest) is used in the present invention, but the fractionation part of any lemon oil having any component composition, such as from the United States and Europe, can be used.
さらに天然のレモン果皮から蒸留、抽出等の方法で得
られた精油の分画部を本発明に用いることが出来る。Furthermore, a fractionation part of essential oil obtained from a natural lemon peel by a method such as distillation or extraction can be used in the present invention.
従って、レモン（Citrus limon,及びその亜種）の果
皮から水蒸気蒸留、抽出など種々の手段により得られた
香料混合物を減圧蒸留することによって、効果分画部を
得ることも出来る。Therefore, the effective fractionation part can be obtained by subjecting the perfume mixture obtained from the peel of lemon (Citrus limon, and its subspecies) by various means such as steam distillation and extraction to vacuum distillation.
“レモン活性分画部”は減圧蒸留以外にも常圧蒸留、
カラムクロマトグラフィー、GC分取等の方法で得ること
が出来るが、工業的な観点からは減圧蒸留が望ましいと
考えられる。これらの“レモン活性分画部”は、単独ま
たは“レモン活性分画部”と混合可能な様々な媒体（例
えばエタノール、調香料、賦香製品）との混合組成物と
して用いられる。"Lemon active fractionation" is atmospheric distillation, in addition to vacuum distillation,
Although it can be obtained by a method such as column chromatography or GC fractionation, it is considered that vacuum distillation is desirable from an industrial viewpoint. These “lemon active fractions” are used alone or as a mixed composition with various media (eg, ethanol, flavoring, perfuming products) that can be mixed with the “lemon active fraction”.
媒体に調合香料を用いる場合は、調合香料全体の香り
は個々の成分の香りが寄与することとなるが、前述の通
り“レモン活性分画部”は微弱な柑橘系の芳香を有する
から調合香料全体の芳香のバランスに悪影響を与えな
い。When a mixed flavor is used as a medium, the scent of the individual ingredients contributes to the fragrance of the whole mixed flavor. However, as described above, since the “lemon active fractionation part” has a weak citrus fragrance, the mixed flavor is used. Does not adversely affect the overall aroma balance.
この点から“レモン活性分画部”の使用量はかなり自
由度が高く“レモン活性分画部”を重量比で１％以上調
合香料に配合しても全体の香調のバランスをそこなうこ
となく意識高揚効果を発現させることができる。From this point, the amount of the "lemon active fraction" used is quite flexible, and even if the "lemon active fraction" is blended with the flavoring compound by 1% or more by weight, the overall fragrance balance is maintained. The effect of raising awareness can be exhibited.
さらに意識高揚効果を顕著に発現させるという観点か
ら見た場合“レモン活性分画部”を重量比で５％から50
％の範囲で調合香料中に配合することが出来る。In addition, when viewed from the standpoint of remarkably expressing the consciousness-raising effect, the “lemon active fractionation part” is 5% to 50% by weight.
% Can be blended in the blended fragrance.
また、媒体として“レモン活性分画部”単独または上
に記載した“レモン活性分画部”を含有する香料組成物
をエチルアルコールと混合し、用いることも出来る。As a medium, a perfume composition containing "lemon active fraction" alone or the above-mentioned "lemon active fraction" may be mixed with ethyl alcohol and used.
また“レモン活性分画部”単独、または上に記載した
“レモン活性分画部”を含有する香料組成物を用いて、
担体としての賦香製品に賦香することもできる。そのよ
うな賦香製品としては、室内芳香剤、室内消臭剤、エア
ゾール製品などがある。Also, using the "lemon active fraction" alone or the fragrance composition containing the "lemon active fraction" described above,
Flavoring can also be performed on a flavoring product as a carrier. Such fragrance products include room fragrances, room deodorants, aerosol products and the like.
［薬理効果］ 1.マウスに対する麻酔薬作用時間延長効果 （１）実験方法 ICR系雄性マウス（６〜７週齢、体重30〜35g）に、下
記の被験物質を含む空気流（１〜2mgの被験物質を含む
空気を毎分21供給）を４時間吸入させた群と、物質を吸
入させない群のペントバルビタール睡眠時間（55mg/kg
腹注）の差を比較した。[Pharmacological effect] 1. Effect of prolonging the action of anesthetic on mice (1) Experimental method ICR male mice (6-7 weeks old, body weight 30-35 g) were air-flowed with the following test substances (1-2 mg). Pentobarbital sleep time (55 mg / kg) between the group in which the air containing the test substance was supplied at 21 min / min) for 4 hours and the group not inhaling the substance
Intravenous) were compared.
（２）被験物質 物質A:Lemon naardenized S oil（クエスト社より入
手） 物質B:“レモン活性分画部” 実験結果を表.1に示す。(2) Test substance Substance A: Lemon naardenized S oil (obtained from Quest) Substance B: “Lemon active fractionation part” The experimental results are shown in Table 1.
［投与方法、投与量］ 本発明は吸入による投与を特徴とするものであり経口
投与、皮下注射、筋肉注射などによる興奮剤とはとは異
なり、健常人に対して与えた場合に興奮剤よりも緩和な
意識鎮静効果を期待するものであるから上に述べた“レ
モン活性分画部”をアルコールあるいは香料などを含む
組成物の一部として、または賦香製品に用いられた香料
の組成物の一部として与えることが望ましい。 [Administration Method and Dosage] The present invention is characterized by administration by inhalation, and is different from stimulants by oral administration, subcutaneous injection, intramuscular injection, etc. The above-mentioned "lemon active fraction" is expected to have a mild consciousness-sedation effect, as a part of a composition containing alcohol or a fragrance, or a fragrance composition used in a perfume product It is desirable to give as a part of.
本発明の意識を高揚させる室内用芳香剤の効果は年齢
個人差、性別、心身状態などに影響されるので、場合に
よっては下記範囲外量を投与する場合も生ずるが、一般
に健常人を対象とする場合“レモン活性分画部”を0.1
％から５％含む賦香製品から揮散する香気により“レモ
ン活性分画部”を有効量一定時間あるいは継続的に吸入
投与することが好ましい。Since the effect of the indoor air freshener that enhances the consciousness of the present invention is affected by individual differences of age, sex, mental and physical condition, etc., in some cases, a dose outside the following range may be administered, but it is generally intended for healthy persons. If you use “lemon active fractionation” 0.1
The effective amount of the "lemon active fraction" is preferably administered by inhalation for a certain period of time or continuously due to the aroma volatilized from the flavoring product containing from 5% to 5%.
［実施例］ つぎに実施例をあげて、本発明を具体的に明らかにす
る。本発明はこれにより限定されるものではない。配合
量は重量％である。EXAMPLES Next, the present invention will be specifically described with reference to examples. The present invention is not limited by this. The compounding amount is% by weight.
実施例 室内用エアスプレー 以下の処方によりエアゾールに充填した。Example Indoor air spray An aerosol was filled according to the following formulation.
“レモン活性分画部”を15％含む調香料 ５ エチルアルコール95％ 56 スパン 85 ２ ツイン 81 １プロペラント 36 100 これらのエアゾールは香気吸入により、人間の意識水
準を高揚させる効果を持つ。Flavor containing 15% of "lemon active fraction" 5 Ethyl alcohol 95% 56 Span 85 2 Twin 81 1 Propellant 36 100 These aerosols have the effect of raising the level of human awareness by inhaling aroma.
［発明の効果］ 本発明は、ヒトまたは動物が日常生活で経験する眠
け、疲労感惰気などの意識水準の低下による生理心理的
状態から開放し、気分を爽快にするとともに精神活動を
活発化させるなどの意識水準を高揚させる効果を有する
ものである。[Effects of the Invention] The present invention relieves the physio-psychological state caused by a decrease in the level of consciousness, such as sleepiness and fatigue, that humans or animals experience in daily life, makes the mood refreshed, and activates mental activities. It has the effect of raising the level of consciousness, such as raising awareness.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 庁内整理番号 ＦＩ 技術表示箇所 Ｃ１１Ｂ 9/00 Ｃ１１Ｂ 9/00 Ｚ 9/02 9/02 Ｃ１１Ｄ 9/44 Ｃ１１Ｄ 9/44 (72)発明者 中山 靖久 神奈川県横浜市港北区新羽町1050番地 株式会社資生堂研究所内 (56)参考文献 特開 昭59−68399（ＪＰ，Ａ) 特開 昭58−127797（ＪＰ，Ａ) 特開 昭62−84194（ＪＰ，Ａ) 特開 昭61−91297（ＪＰ，Ａ) 特開 昭62−275199（ＪＰ，Ａ) 特開 昭56−70096（ＪＰ，Ａ) 特公 昭59−8391（ＪＰ，Ｂ２) 特公 昭60−6992（ＪＰ，Ｂ２) 特公 昭60−6993（ＪＰ，Ｂ２) 特公 昭60−19955（ＪＰ，Ｂ２) 特公 昭60−17479（ＪＰ，Ｂ２) 香料、ＮＯ．140，（1983），Ｐ．19 −26，奥田治、”アロマテラピー展望"──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 6 Identification code Agency reference number FI Technical display location C11B 9/00 C11B 9/00 Z 9/02 9/02 C11D 9/44 C11D 9/44 (72 ) Inventor Yasuhisa Nakayama 1050 Nippa-cho, Kohoku-ku, Yokohama City, Kanagawa Prefecture Inside Shiseido Research Laboratories Co., Ltd. (56) References JP-A-59-68399 (JP, A) 62-84194 (JP, A) JP-A-61-91297 (JP, A) JP-A-62-275199 (JP, A) JP-A-56-70096 (JP, A) JP-B-59-8391 (JP, A) B2) Japanese Patent Publication No. 60-6992 (JP, B2) Japanese Patent Publication No. 60-6993 (JP, B2) Japanese Patent Publication No. 60-19955 (JP, B2) Japanese Patent Publication No. 60-17479 (JP, B2) Fragrance, NO. 140, (1983), p. 19-26, Osamu Okuda, "Aromatherapy Prospects"
Claims (1)
℃以前に留出する部分を除いたレモン油分画部を有効成
分として配合したことを特長とする、ヒトまたは動物の
意識水準を高揚させる効果をもつ室内用芳香剤。(1) A vacuum distillation method under a pressure of 0.08 mmHg,
An indoor air freshener having an effect of raising the level of consciousness of humans or animals, characterized by containing as an active ingredient a lemon oil fraction excluding a portion distilled off before ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63083714A JP2614484B2 (en) | 1988-04-05 | 1988-04-05 | Indoor air freshener with the effect of raising awareness level |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63083714A JP2614484B2 (en) | 1988-04-05 | 1988-04-05 | Indoor air freshener with the effect of raising awareness level |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01254629A JPH01254629A (en) | 1989-10-11 |
| JP2614484B2 true JP2614484B2 (en) | 1997-05-28 |
Family
ID=13810172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63083714A Expired - Fee Related JP2614484B2 (en) | 1988-04-05 | 1988-04-05 | Indoor air freshener with the effect of raising awareness level |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2614484B2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5741481A (en) * | 1994-07-27 | 1998-04-21 | Picken, Jr.; Henry M. | Cosmetics containing citrus water distillate |
| US5853730A (en) * | 1996-08-22 | 1998-12-29 | Picken, Jr.; Henry M. | Cleaning solution using citrus water distillate |
| JP5053472B2 (en) * | 1999-07-09 | 2012-10-17 | 株式会社 資生堂 | Fragrance composition |
| WO2002030377A2 (en) * | 2000-10-09 | 2002-04-18 | Karen Croissant | Product for cleaning teeth and/or the mouth |
| KR100910728B1 (en) * | 2001-08-08 | 2009-08-05 | 가부시키가이샤 시세이도 | Perfume compositions |
| US20080096790A1 (en) * | 2006-10-23 | 2008-04-24 | Quest International Services B.V. | Fragrance compositions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5670096A (en) * | 1979-11-12 | 1981-06-11 | Takasago Perfumery Co Ltd | Manufacture of lemon oil having no phototoxicity |
| JPS58127797A (en) * | 1982-01-25 | 1983-07-29 | 小林香料株式会社 | Purification of bergamot oil |
| JPS598391A (en) * | 1982-07-05 | 1984-01-17 | 日本電気株式会社 | Solder plate for mounting planarly |
| JPS5968399A (en) * | 1982-10-13 | 1984-04-18 | 株式会社 小林コ−セ− | Manufacture of low sensitive low irritant jasmine oil |
| US4555700A (en) * | 1983-05-11 | 1985-11-26 | International Business Machines Corp. | Internal image and bit array for display and printing of graphics |
| JPS606992A (en) * | 1983-06-27 | 1985-01-14 | 株式会社日立製作所 | Display unit |
| DE3323761A1 (en) * | 1983-07-01 | 1985-01-03 | Robert Bosch Gmbh, 7000 Stuttgart | FUEL INJECTION PUMP FOR INTERNAL COMBUSTION ENGINES |
| JPH0762743B2 (en) * | 1983-07-09 | 1995-07-05 | キヤノン株式会社 | Liquid crystal device |
| JPH06919B2 (en) * | 1984-10-12 | 1994-01-05 | 鐘紡株式会社 | Method for producing ylang-ylang oil with excellent fragrance and low sensitization |
| JPS6284194A (en) * | 1985-10-08 | 1987-04-17 | カネボウ株式会社 | Production of iranian oil excellent in flavor and low in sensitivity |
| JPH0816232B2 (en) * | 1986-05-22 | 1996-02-21 | 長谷川香料株式会社 | Manufacturing method of non-phototoxic orange flower essential oil |
-
1988
- 1988-04-05 JP JP63083714A patent/JP2614484B2/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 香料、ＮＯ．１４０，（１９８３），Ｐ．１９−２６，奥田治、"アロマテラピー展望" |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01254629A (en) | 1989-10-11 |
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