JP2609780B2 - Diabetes treatment - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention is intended to reduce blood sugar levels naturally by reducing or eliminating various symptoms of an estimated 2 million diabetic patients, and to reliably prevent blood sugar levels from re-elevating. The present invention relates to a drug for treating diabetes.

[0002]

2. Description of the Related Art As a therapeutic agent for diabetes, human insulin by genetic manipulation is used, and as an oral diabetes agent, there are various agents such as sulfonylureas, sulfonamides, biguanides, etc. It is also intended to reduce or eliminate various symptoms of diabetes by lowering the blood sugar level of diabetic patients, and to reduce the blood sugar level by reducing or eliminating various symptoms of diabetes. There was nothing before.

[0003] In addition, it has been reported that cyclosporin A, an immunosuppressant, is administered to patients with early-stage insulin-type diabetes to ameliorate the condition, but there are concerns about side effects.

[0004]

In the case of diabetes, glucose level (blood glucose level) in blood increases due to insufficient action of insulin secreted from β cells of the islets of Langerhans of the pancreas.
It presents various symptoms, and according to the WHO expert committee's classification, insulin-dependent (IDDM), non-insulin-dependent (NIDDM), and malnourished (MRD)
M), other types, the estimated number of diabetic patients is 2
It is said to be one million, of which 90% are non-insulin dependent patients.

[0005] Also, a problem as a reserve diabetes army is impaired glucose tolerance (IGT) gestational diabetes mellitus (GDM), and it is estimated that the number of those including the reserve diabetes army will reach 4 million.

[0006] Diabetes occupies an important position as a risk factor for atherosclerotic diseases, and also plays an important role in many diseases and causes of death.

[0007] The blood sugar level, which is known as a numerical value indicating the symptoms of diabetes, is normally maintained at 70 to 140 mg / dl by the action of many hormones such as insulin and glucagon, but it is less than half the normal value. When it comes to life will be threatened. For this reason, diet therapy, exercise therapy, insulin therapy, drug therapy and the like are often used in combination.

[0008] It is an object of the present invention to provide a remedy for diabetes capable of lowering blood sugar levels by alleviating or eliminating various symptoms of diabetes and preventing a rise in blood sugar levels for a long time. I do.

As a means for achieving the above object, the present invention relates to a plant Nitobegiku, a plant Kidachinbai, or a mixture of these plants with a plant butterfly and a plant Mexican sunflower, or a mixture of a plant Mexican sunflower and a plant butterfly. The present invention is to provide a remedy for diabetes comprising a decoction or an extract thereof.

[0010] The decoction or extract can be taken as a powder, tablets or granules by freeze-drying or the like.

The plant Nitobegiku is a plant belonging to the family Chrysanthemum, whose scientific names are Tissonia diversifolia (hemsul) A and gray (Tithonia diversifolia (H).
emsl) A, Gray), and Tsonia Fraticosa Canby and Rose (Ti)
thonia fruticosaCanby & R
ose), Tissonia Scaverimaa Bence (Tit)
honia scabarima Benth), Tissonia Rongeradayata (Bartle) break (T
Ithonia longerdiatiata (Bert
ol) Blake), and so on.

[0012] The plant Mexican sunflower is a plant belonging to the family Chrysanthemum of the same family as the plant Nitobegiku, and its scientific name is Tissonia rotundifolia (mill) break (Tithonia rot).
unfolia (Mill) Blake), which is unique to Japan, is native to part of Kyushu, and is sold as a houseplant.

[0013] The plant Kidachikinbai is a plant belonging to the genus Asclepiadaceae, and has a scientific name of Ludwigia octovalbis raben (Ludwigia octovalvi).
s Raven).

[0014] The plant Asteraceae is a plant belonging to the genus Asteraceae, which belongs to the genus Asteraceae, and has a scientific name of Ludwigia prostrata Rox.
b).

When taking it, first, a decoction based on the plant Nitobegiku of the Chrysanthemum family or the plant Mexican sunflower or its extract is used continuously for two months. Subsequently, a decoction or an extract thereof based on a plant of the family Acabolidae (Kidachikinbai) or a plant of Clover is used for one month.

The amount of decoction is, in the case of an adult, in the case of a plant nitobegiku per day, in severe cases (AC 200 mg / day).
/ Dl or more), add 50 g of crude drug to 3000 CC of water and decoction until it is almost 1/3, and plant Kida Chicken Bai will add 20 g of crude drug to 1800 CC of water regardless of symptoms, and it will be almost 1/3 Up to decoction, but when symptoms are moderate (AC 150-200 mg / d
l) In the case of crude drug 40g in 3000CC water, 3000cc water in case of mild (AC 150mg / dl or less)
It is preferable to use 20 grams of crude drug, but the present invention is not limited to this. In addition, the content of the extract, the method of ingestion, the amount of infusion, and the like may be appropriately increased or decreased according to the symptoms.

[0017] It is preferable to use 20 grams of a crude drug in 1800 CC of water regardless of the condition of the plant.

When drinking, the decoction must be warmed and consumed mainly on an empty stomach, and the radish must not be eaten during the drinking period. Also, it is important not to make more than 3 days and store it in the refrigerator.

[0019]

Embodiments of the present invention will be described below. Example 1 Branches (stems) and leaves of the plant Nitobegiku are collected, dried and cut into small pieces to facilitate decoction. In the case of an adult, add 50 grams daily to 3,000 cc of water, heat at high heat first, and then boil to low heat when boiling, then add 1,000 grams of liquid.
Take out the decoction when it reaches 0 cc. Next, after the decoction is taken out, 600 cc of water is again added and decocted.
Remove 00cc. Mix 1,000 cc of the first decoction and 200 cc of the latter to make the daily amount. It has subjective symptoms of malaise, polyuria, and thirst, and urine sugar: (++
+), White blood cell count in urine residue: 15 to 25 / HPF, white blood cell count (WBC): 11,800 / cmm, blood glucose test: AC
(Fasting) 226 mg / dl, PC (2 hours after meal) 4
59 mg / dl diabetic patients were given several doses on an empty stomach and continued for 2 months. One month after the administration, the symptoms were alleviated and disappeared completely at the second month.

Next, a plant kid's fever is prepared in the same manner, and 20 grams per day is placed in 800 cc of water and decocted to obtain 400 cc of decoction. 400 cc of water was again added to the raw material and decoction was made to make 200 cc of decoction, and both were mixed to give a daily dose, and the patient was continued to take several doses on an empty stomach for one month.

The inspection results at that time were as follows. Subjective symptoms: Complete disappearance of various symptoms, good physical condition, urine sugar:
(-), White blood cell count in urine residue: 2 to 4 / HPF, white blood cell count (WBC): 10,000 / cmm, blood glucose test: AC
(Fasting) 88 mg / dl, PC (2 hours after meal) 15
5 mg / dl.

The test results 3 months after the completion of the administration of the plant Kidachikinibai were as follows. Subjective symptoms: none, urine sugar: (-), leukocyte count in urine residue: 1
~ 2 / HPF, blood glucose test: AC (fasting) 62 mg / d
1, PC (2 hours after meal) 96 mg / dl.

The test results 4 months after the completion of the administration of the plant Kida Chicken Bai were as follows. Subjective symptoms: none, urine sugar: (-), leukocyte count in urine residue: 0
２2 / HPF, blood glucose test: AC (fasting) 79 mg / d
1, PC (2 hours after meal): 111 mg / dl, urinary tract infection characteristic of diabetes was cured at this time.

The results of the tests 4 years after the completion of taking the plant Kidachikinibai were as follows. In addition, to confirm whether the diabetes recurs, the dog was drunk and eaten for one week before the test. Subjective symptoms: none, urine glucose: (-), blood glucose test: AC (fasting) 97 mg / dl, PC (2 hours after meal) 140 mg
/ Dl.

If the decoction of the plant Nitobegiku or its extract is taken, the symptoms disappear, but the symptoms recur unless the decoction of the plant kidachikinbai or its extract is taken. Therefore, it is necessary to take both. This is the same in the second, third and fourth embodiments.

Example 2 When a diabetic patient was drunk with the plant Nitobegiku and the Aspergillus niger in the same manner as in Example 1, almost the same results were obtained.

Example 3 A plant Mexican sunflower and a plant Kidachikinbai were used in Example 1.
When a diabetic patient was drunk in the same manner as described above, almost the same results were obtained.

Example 4 When a diabetic patient was drunk with the plant Mexican sunflower and the plant mushroom in the same manner as in Example 1, almost the same results were obtained.

The remedy for diabetes of the present invention is constituted as described above, and is based on a decoction based on a plant Nitobegiku or a plant Mexican sunflower, or an extract thereof, or a plant Nitobegiku and a plant Chojitade. Taking decoction, extract, etc., or decoction, extract, etc. based on the plant Mexican sunflower and the plant Kidachikinbai, or decoction, extract, etc. based on the plant Mexican sunflower and the plant clover, may cause various diabetes. Symptoms are reduced / eliminated, and then urine sugar and blood sugar levels spontaneously fall to normal levels and are completely cured.

The antidiabetic agent of the present invention naturally reduces urinary glucose and blood glucose level by reducing or eliminating various symptoms of diabetes, and forcibly lowers blood glucose level as in the conventional case. It is safe because it does not cause hypoglycemia, and can prevent a rise in blood glucose level for a long time thereafter.

The mechanism of its action is not clear, but it is considered that its administration causes an insulin-like effect directly on peripheral tissue cells such as liver and adipocytes. It is also presumed that an antibody that acts on a substance that suppresses glucose metabolism and suppresses its action is formed in the body by an antigen-antibody reaction.

Further, it is considered that the crude drug component acts on a substance that reduces the absorption capacity of blood insulin of a diabetic patient as a medicinal mechanism, and further, the crude drug component contains a certain protein, This is likely to bind to insulin, enter cells through cell membranes, reduce glucose metabolism abnormalities, and lead to healing.

Claims (5)

(57) [Claims] 1. A remedy for diabetes comprising a decoction or an extract thereof based on the plant Nitobegiku. 2. A remedy for diabetes based on the plant Kidachikinbai . 3. A remedy for diabetes comprising a decoction or an extract thereof based on a plant Nitobegiku and a plant Clovenia . 4. Plant Mexican sunflower and plant Kidachikin
Anti- diabetic drug based on bi . 5. A plant Mexican sunflower and a plant Chometa
De-based antidiabetic drug.