JP2026502231A - 補体因子ｂ阻害剤、その医薬組成物および使用 - Google Patents

補体因子ｂ阻害剤、その医薬組成物および使用

Info

Publication number
JP2026502231A
JP2026502231A JP2025538315A JP2025538315A JP2026502231A JP 2026502231 A JP2026502231 A JP 2026502231A JP 2025538315 A JP2025538315 A JP 2025538315A JP 2025538315 A JP2025538315 A JP 2025538315A JP 2026502231 A JP2026502231 A JP 2026502231A
Authority
JP
Japan
Prior art keywords
alkyl
alkylene
optionally substituted
cycloalkyl
membered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025538315A
Other languages
English (en)
Japanese (ja)
Other versions
JP2026502231A5 (enExample
Inventor
グ，チェンソン
ジ，ファンヤン
シャオ，シュンジエ
チョウ，ユアン
チェン，ジァオシァン
シュ，メンヤン
バイ，ルー
ルオ，ジエ
ファン，レイ
チェン，ビン
ワン，シャオヘイ
チァン，ペイユ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhuhai United Laboratories Co Ltd
Original Assignee
Zhuhai United Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhuhai United Laboratories Co Ltd filed Critical Zhuhai United Laboratories Co Ltd
Publication of JP2026502231A publication Critical patent/JP2026502231A/ja
Publication of JP2026502231A5 publication Critical patent/JP2026502231A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2025538315A 2022-12-31 2023-12-29 補体因子ｂ阻害剤、その医薬組成物および使用 Pending JP2026502231A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202211737515 2022-12-31
CN202211737515.0 2022-12-31
CN202310699631 2023-06-13
CN202310699631.6 2023-06-13
PCT/CN2023/143205 WO2024141011A1 (zh) 2022-12-31 2023-12-29 补体因子b抑制剂及其药物组合物和应用

Publications (2)

Publication Number Publication Date
JP2026502231A true JP2026502231A (ja) 2026-01-21
JP2026502231A5 JP2026502231A5 (enExample) 2026-05-08

Family

ID=91716537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025538315A Pending JP2026502231A (ja) 2022-12-31 2023-12-29 補体因子ｂ阻害剤、その医薬組成物および使用

Country Status (3)

Country Link
JP (1) JP2026502231A (enExample)
CN (1) CN120435467A (enExample)
WO (1) WO2024141011A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026002007A1 (zh) * 2024-06-25 2026-01-02 珠海联邦制药股份有限公司 补体因子b抑制剂及其药物组合物和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512134A (ja) * 2008-08-19 2012-05-31 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 冷感−メントール受容体拮抗剤
WO2012135697A2 (en) * 2011-03-30 2012-10-04 H. Lee Moffitt Cancer Center & Research Institute Inc. Novel rho kinase inhibitors and methods of use
WO2013129338A1 (ja) * 2012-02-29 2013-09-06 ポリプラスチックス株式会社 カメラモジュール用液晶性樹脂組成物
WO2016077240A2 (en) * 2014-11-10 2016-05-19 Forge Life Science, Llc Anti-hcmv compositions and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103402996B (zh) * 2011-01-04 2015-02-11 诺瓦提斯公司 可用于治疗年龄相关性黄斑变性(amd)的吲哚化合物或其类似物
SG11201406973PA (en) * 2012-05-04 2014-12-30 Novartis Ag Complement pathway modulators and uses thereof
JO3425B1 (ar) * 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
HRP20251596T1 (hr) * 2017-08-31 2026-01-30 Novartis Ag Nove upotrebe derivata piperidinil-indola
KR20230049115A (ko) * 2020-08-07 2023-04-12 상하이 메이유에 바이오테크 디벨롭먼트 컴퍼니 리미티드 보체 인자 b 억제제 및 이의 약학적 조성물, 제조 방법 및 용도

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512134A (ja) * 2008-08-19 2012-05-31 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 冷感−メントール受容体拮抗剤
WO2012135697A2 (en) * 2011-03-30 2012-10-04 H. Lee Moffitt Cancer Center & Research Institute Inc. Novel rho kinase inhibitors and methods of use
WO2013129338A1 (ja) * 2012-02-29 2013-09-06 ポリプラスチックス株式会社 カメラモジュール用液晶性樹脂組成物
WO2016077240A2 (en) * 2014-11-10 2016-05-19 Forge Life Science, Llc Anti-hcmv compositions and methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMISTRY & BIOLOGY 20, 370-378, 2013, JPN6026023872, ISSN: 0005881671 *

Also Published As

Publication number Publication date
CN120435467A (zh) 2025-08-05
WO2024141011A1 (zh) 2024-07-04

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