JP2026009862A5 - - Google Patents
Info
- Publication number
- JP2026009862A5 JP2026009862A5 JP2025114710A JP2025114710A JP2026009862A5 JP 2026009862 A5 JP2026009862 A5 JP 2026009862A5 JP 2025114710 A JP2025114710 A JP 2025114710A JP 2025114710 A JP2025114710 A JP 2025114710A JP 2026009862 A5 JP2026009862 A5 JP 2026009862A5
- Authority
- JP
- Japan
- Prior art keywords
- double
- pharmaceutical composition
- composition according
- rnai agent
- stranded rnai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410909405 | 2024-07-08 | ||
| CN2024109094050 | 2024-07-08 | ||
| CN202510037618.3A CN119752912B (zh) | 2024-07-08 | 2025-01-09 | 靶向调控HBV基因表达的siRNA及其应用 |
| CN2025100376183 | 2025-01-09 | ||
| CN202510039613.4A CN119799706B (zh) | 2024-07-08 | 2025-01-09 | 靶向调控HBV基因表达的siRNA及其应用 |
| CN2025100393920 | 2025-01-09 | ||
| CN2025100396134 | 2025-01-09 | ||
| CN202510039392.0A CN119799705B (zh) | 2024-07-08 | 2025-01-09 | 靶向调控HBV基因表达的siRNA及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026009862A JP2026009862A (ja) | 2026-01-21 |
| JP2026009862A5 true JP2026009862A5 (https=) | 2026-04-06 |
Family
ID=96343514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025114710A Pending JP2026009862A (ja) | 2024-07-08 | 2025-07-07 | ＨＢＶ遺伝子発現を標的にして調整・制御する二本鎖ＲＮＡｉ剤およびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4678747A3 (https=) |
| JP (1) | JP2026009862A (https=) |
| KR (1) | KR20260008676A (https=) |
| AU (1) | AU2025205193A1 (https=) |
| CA (1) | CA3279332A1 (https=) |
| IL (1) | IL322012A (https=) |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101728655B1 (ko) | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| US20100249214A1 (en) | 2009-02-11 | 2010-09-30 | Dicerna Pharmaceuticals | Multiplex dicer substrate rna interference molecules having joining sequences |
| KR101766408B1 (ko) | 2009-06-10 | 2017-08-10 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
| IL292159B1 (en) | 2012-12-05 | 2026-04-01 | Alnylam Pharmaceuticals Inc | PCSK9 iRNA compositions and methods of using them |
| HRP20230209T1 (hr) | 2015-10-28 | 2023-04-14 | Acuitas Therapeutics Inc. | Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina |
| EP4186888B1 (en) | 2017-03-15 | 2025-11-26 | ModernaTX, Inc. | Compound and compositions for intracellular delivery of therapeutic agents |
| JP7625512B2 (ja) * | 2018-08-13 | 2025-02-03 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | Ｂ型肝炎ウイルス（ＨＢＶ）ｄｓＲＮＡ物質組成物およびその使用方法 |
| WO2020163747A1 (en) * | 2019-02-07 | 2020-08-13 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for hepatitis b virus infection |
| MA55375A (fr) * | 2019-03-20 | 2022-01-26 | Arbutus Biopharma Corp | Méthodes thérapeutiques de traitement de l'hépatite b |
| JP7455336B2 (ja) * | 2019-03-26 | 2024-03-26 | 富士フイルム株式会社 | Ｂ型肝炎ウイルスタンパク質の産生を阻害する医薬組成物およびスクリーニング方法 |
| PH12021552870A1 (en) * | 2019-05-13 | 2022-03-21 | Vir Biotechnology Inc | Compositions and methods for treating hepatitis b virus (hbv) infection |
| WO2021110148A1 (zh) * | 2019-12-06 | 2021-06-10 | 南京明德新药研发有限公司 | siRNA缀合物、双链siRNA缀合物及其盐和应用 |
| TW202221122A (zh) * | 2020-08-05 | 2022-06-01 | 瑞士商赫孚孟拉羅股份公司 | Ｂ型肝炎患者之寡核苷酸治療 |
| EP4223876A4 (en) * | 2020-09-30 | 2025-12-10 | Fujifilm Corp | DOUBLE-STRANDED RNA THAT INHIBITS THE PRODUCTION OF A HEPATITIS B VIRUS PROTEIN, AND PHARMACEUTICAL COMPOSITION |
| US20240124879A1 (en) * | 2020-12-18 | 2024-04-18 | Olix Pharmaceuticals, Inc. | Rnai agent for inhibiting hbv expression and use thereof |
| CA3235672A1 (en) * | 2021-11-29 | 2023-06-01 | Shanghai Argo Biopharmaceutical Co., Ltd. | Compositions and methods for inhibiting expression of hepatitis b virus (hbv) protein |
| CN114044741B (zh) | 2022-01-13 | 2022-04-15 | 北京悦康科创医药科技股份有限公司 | 一种阳离子脂质化合物、包含其的组合物及用途 |
| CN115745820B (zh) | 2023-01-05 | 2023-04-28 | 北京悦康科创医药科技股份有限公司 | 长效低毒的新型阳离子脂质化合物及其组合物 |
| CN115677518B (zh) | 2023-01-05 | 2023-04-14 | 北京悦康科创医药科技股份有限公司 | 用于递送核酸的可电离阳离子脂质化合物和组合物及用途 |
| CN115784921B (zh) | 2023-02-08 | 2023-05-05 | 北京悦康科创医药科技股份有限公司 | 肝外靶向高效低毒的阳离子脂质化合物及其组合物 |
| CN116854754B (zh) | 2023-09-01 | 2023-12-12 | 北京悦康科创医药科技股份有限公司 | 一种含有核糖环或其衍生结构的GalNAc化合物及其寡核苷酸缀合物 |
-
2025
- 2025-07-07 KR KR1020250090998A patent/KR20260008676A/ko active Pending
- 2025-07-07 CA CA3279332A patent/CA3279332A1/en active Pending
- 2025-07-07 AU AU2025205193A patent/AU2025205193A1/en active Pending
- 2025-07-07 JP JP2025114710A patent/JP2026009862A/ja active Pending
- 2025-07-08 EP EP25188148.8A patent/EP4678747A3/en active Pending
- 2025-07-08 IL IL322012A patent/IL322012A/en unknown
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