JP2025518522A5 - - Google Patents
Info
- Publication number
- JP2025518522A5 JP2025518522A5 JP2024568256A JP2024568256A JP2025518522A5 JP 2025518522 A5 JP2025518522 A5 JP 2025518522A5 JP 2024568256 A JP2024568256 A JP 2024568256A JP 2024568256 A JP2024568256 A JP 2024568256A JP 2025518522 A5 JP2025518522 A5 JP 2025518522A5
- Authority
- JP
- Japan
- Prior art keywords
- antisense oligonucleotide
- oligonucleotide according
- sequence
- group
- cholesterol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22174186 | 2022-05-18 | ||
| EP22174186.1 | 2022-05-18 | ||
| PCT/EP2023/063442 WO2023222858A1 (en) | 2022-05-18 | 2023-05-18 | Improved oligonucleotides targeting rna binding protein sites |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025518522A JP2025518522A (ja) | 2025-06-17 |
| JP2025518522A5 true JP2025518522A5 (OSRAM) | 2026-05-21 |
Family
ID=82308571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024568256A Pending JP2025518522A (ja) | 2022-05-18 | 2023-05-18 | Ｒｎａ結合タンパク質部位を標的とする改善されたオリゴヌクレオチド |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20250290068A2 (OSRAM) |
| EP (1) | EP4526445A1 (OSRAM) |
| JP (1) | JP2025518522A (OSRAM) |
| KR (1) | KR20250011958A (OSRAM) |
| CN (1) | CN119213124A (OSRAM) |
| AR (1) | AR129362A1 (OSRAM) |
| AU (1) | AU2023270744A1 (OSRAM) |
| CA (1) | CA3257367A1 (OSRAM) |
| CL (1) | CL2024003521A1 (OSRAM) |
| CO (1) | CO2024017326A2 (OSRAM) |
| CR (1) | CR20240492A (OSRAM) |
| IL (1) | IL316608A (OSRAM) |
| MX (1) | MX2024014159A (OSRAM) |
| PE (1) | PE20250394A1 (OSRAM) |
| TW (1) | TW202409276A (OSRAM) |
| WO (1) | WO2023222858A1 (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7836475B1 (ja) | 2024-03-05 | 2026-03-26 | 武田薬品工業株式会社 | Ｕｎｃ１３ａのスプライシングモジュレーションのための組成物および方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| CA2303299C (en) | 1997-09-12 | 2016-02-23 | Exiqon A/S | Oligonucleotide analogues |
| PT1152009E (pt) | 1999-02-12 | 2005-03-31 | Sankyo Co | Novos analogos de nucleosidos e oligonucleotidos |
| NZ514348A (en) | 1999-05-04 | 2004-05-28 | Exiqon As | L-ribo-LNA analogues |
| US6617442B1 (en) | 1999-09-30 | 2003-09-09 | Isis Pharmaceuticals, Inc. | Human Rnase H1 and oligonucleotide compositions thereof |
| US9045518B2 (en) | 2002-11-18 | 2015-06-02 | Santaris Pharma A/S | Amino-LNA, thio-LNA and alpha-L-oxy-LN |
| ES2351674T3 (es) | 2006-01-27 | 2011-02-09 | Isis Pharmaceuticals, Inc. | Análogos de ácidos nucleicos bicíclicos modificados en la posición 6. |
| US7666854B2 (en) | 2006-05-11 | 2010-02-23 | Isis Pharmaceuticals, Inc. | Bis-modified bicyclic nucleic acid analogs |
| CA2651453C (en) | 2006-05-11 | 2014-10-14 | Isis Pharmaceuticals, Inc. | 5'-modified bicyclic nucleic acid analogs |
| EP2170917B1 (en) | 2007-05-30 | 2012-06-27 | Isis Pharmaceuticals, Inc. | N-substituted-aminomethylene bridged bicyclic nucleic acid analogs |
| EP2173760B2 (en) | 2007-06-08 | 2015-11-04 | Isis Pharmaceuticals, Inc. | Carbocyclic bicyclic nucleic acid analogs |
| EP2176280B2 (en) | 2007-07-05 | 2015-06-24 | Isis Pharmaceuticals, Inc. | 6-disubstituted bicyclic nucleic acid analogs |
| WO2009067647A1 (en) | 2007-11-21 | 2009-05-28 | Isis Pharmaceuticals, Inc. | Carbocyclic alpha-l-bicyclic nucleic acid analogs |
| US8501805B2 (en) | 2008-09-24 | 2013-08-06 | Isis Pharmaceuticals, Inc. | Substituted alpha-L-bicyclic nucleosides |
| US9012421B2 (en) | 2009-08-06 | 2015-04-21 | Isis Pharmaceuticals, Inc. | Bicyclic cyclohexose nucleic acid analogs |
| WO2011156202A1 (en) | 2010-06-08 | 2011-12-15 | Isis Pharmaceuticals, Inc. | Substituted 2 '-amino and 2 '-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom |
| EP2850092B1 (en) | 2012-04-09 | 2017-03-01 | Ionis Pharmaceuticals, Inc. | Tricyclic nucleic acid analogs |
| SG10201804331TA (en) | 2012-11-15 | 2018-07-30 | Roche Innovation Ct Copenhagen As | Oligonucleotide conjugates |
| JP2017505623A (ja) | 2014-01-30 | 2017-02-23 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 生物切断性コンジュゲートを有するポリオリゴマー化合物 |
| US11833168B2 (en) | 2018-06-14 | 2023-12-05 | Ionis Pharmaceuticals, Inc. | Compounds and methods for increasing STMN2 expression |
| MX2021005357A (es) * | 2018-11-08 | 2021-06-30 | Aligos Therapeutics Inc | Polimeros oligonucleotidos que inhiben el transporte de antigeno s y metodos. |
| WO2022018187A1 (en) * | 2020-07-23 | 2022-01-27 | F. Hoffmann-La Roche Ag | Oligonucleotides targeting rna binding protein sites |
| CN118434858A (zh) * | 2021-12-07 | 2024-08-02 | 豪夫迈·罗氏有限公司 | 靶向actl6b的反义寡核苷酸 |
-
2023
- 2023-05-18 KR KR1020247041783A patent/KR20250011958A/ko active Pending
- 2023-05-18 IL IL316608A patent/IL316608A/en unknown
- 2023-05-18 CR CR20240492A patent/CR20240492A/es unknown
- 2023-05-18 PE PE2024002546A patent/PE20250394A1/es unknown
- 2023-05-18 AR ARP230101237A patent/AR129362A1/es unknown
- 2023-05-18 TW TW112118586A patent/TW202409276A/zh unknown
- 2023-05-18 JP JP2024568256A patent/JP2025518522A/ja active Pending
- 2023-05-18 CN CN202380040019.6A patent/CN119213124A/zh active Pending
- 2023-05-18 AU AU2023270744A patent/AU2023270744A1/en active Pending
- 2023-05-18 WO PCT/EP2023/063442 patent/WO2023222858A1/en not_active Ceased
- 2023-05-18 EP EP23723219.4A patent/EP4526445A1/en active Pending
- 2023-05-18 CA CA3257367A patent/CA3257367A1/en active Pending
-
2024
- 2024-11-15 MX MX2024014159A patent/MX2024014159A/es unknown
- 2024-11-15 US US18/948,897 patent/US20250290068A2/en active Pending
- 2024-11-18 CL CL2024003521A patent/CL2024003521A1/es unknown
- 2024-12-17 CO CONC2024/0017326A patent/CO2024017326A2/es unknown
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