JP2025513714A5 - - Google Patents

Info

Publication number
JP2025513714A5
JP2025513714A5 JP2024556078A JP2024556078A JP2025513714A5 JP 2025513714 A5 JP2025513714 A5 JP 2025513714A5 JP 2024556078 A JP2024556078 A JP 2024556078A JP 2024556078 A JP2024556078 A JP 2024556078A JP 2025513714 A5 JP2025513714 A5 JP 2025513714A5
Authority
JP
Japan
Prior art keywords
seq
antibody
antigen
binding fragment
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024556078A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025513714A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/057248 external-priority patent/WO2023180346A1/en
Publication of JP2025513714A publication Critical patent/JP2025513714A/ja
Publication of JP2025513714A5 publication Critical patent/JP2025513714A5/ja
Pending legal-status Critical Current

Links

JP2024556078A 2022-03-22 2023-03-21 Cd3に特異的な脱免疫抗体 Pending JP2025513714A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22163663.2 2022-03-22
EP22163663 2022-03-22
PCT/EP2023/057248 WO2023180346A1 (en) 2022-03-22 2023-03-21 Deimmunized antibodies specific for cd3

Publications (2)

Publication Number Publication Date
JP2025513714A JP2025513714A (ja) 2025-04-30
JP2025513714A5 true JP2025513714A5 (enExample) 2026-05-12

Family

ID=80930505

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024556078A Pending JP2025513714A (ja) 2022-03-22 2023-03-21 Cd3に特異的な脱免疫抗体

Country Status (9)

Country Link
US (1) US20250206819A1 (enExample)
EP (1) EP4496812A1 (enExample)
JP (1) JP2025513714A (enExample)
KR (1) KR20240158351A (enExample)
CN (1) CN118922448A (enExample)
AU (1) AU2023240297A1 (enExample)
CA (1) CA3246381A1 (enExample)
IL (1) IL315591A (enExample)
WO (1) WO2023180346A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025087681A1 (en) 2023-10-26 2025-05-01 Morphosys Ag Bispecific antibodies against cd3 and cd20
WO2025106469A1 (en) * 2023-11-14 2025-05-22 Regeneron Pharmaceuticals, Inc. Engineered heavy chain variable domains and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE255131T1 (de) 1991-06-14 2003-12-15 Genentech Inc Humanisierter heregulin antikörper
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
WO1998052976A1 (en) 1997-05-21 1998-11-26 Biovation Limited Method for the production of non-immunogenic proteins
JP3614866B2 (ja) 1997-06-12 2005-01-26 リサーチ コーポレイション テクノロジーズ,インコーポレイティド 人工抗体ポリペプチド
EP1051432B1 (en) 1998-12-08 2007-01-24 Biovation Limited Method for reducing immunogenicity of proteins
EP1990409A3 (en) 1999-07-20 2011-05-18 MorphoSys AG Bacteriophage
AU2003236728A1 (en) 2002-06-10 2003-12-22 Algonomics N.V. Method for predicting the binding affinity of mhc/peptide complexes
JP6040148B2 (ja) 2010-04-20 2016-12-07 ゲンマブ エー/エス ヘテロ二量体抗体Fc含有タンパク質およびその産生方法
CA3051311A1 (en) 2010-05-27 2011-12-01 Genmab A/S Monoclonal antibodies against her2
HRP20181811T1 (hr) 2010-11-19 2018-12-28 Morphosys Ag Zbirka sljedova protutijela i njezina upotreba
DK2771364T3 (da) 2011-10-27 2019-08-19 Genmab As Fremstilling af heterodimere proteiner
ES2742224T3 (es) * 2013-11-07 2020-02-13 Memorial Sloan Kettering Cancer Center Anticuerpos biespecíficos anti-WT1/HLA
RU2016151235A (ru) * 2014-05-28 2018-06-28 Ф. Хоффманн-Ля Рош Аг Антитела, связывающиеся с cd3 эпсилон человека и обезьян циномолгус
US11472880B2 (en) * 2017-08-14 2022-10-18 Morphosys Ag Humanized antibodies for CD3
CA3121699A1 (en) 2018-12-05 2020-06-11 Morphosys Ag Multispecific antigen-binding molecules

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