JP2025512469A5 - - Google Patents

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Publication number
JP2025512469A5
JP2025512469A5 JP2024560676A JP2024560676A JP2025512469A5 JP 2025512469 A5 JP2025512469 A5 JP 2025512469A5 JP 2024560676 A JP2024560676 A JP 2024560676A JP 2024560676 A JP2024560676 A JP 2024560676A JP 2025512469 A5 JP2025512469 A5 JP 2025512469A5
Authority
JP
Japan
Prior art keywords
antibody
light chain
seq
heavy chain
constant region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024560676A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512469A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/065764 external-priority patent/WO2023201324A1/en
Publication of JP2025512469A publication Critical patent/JP2025512469A/ja
Publication of JP2025512469A5 publication Critical patent/JP2025512469A5/ja
Pending legal-status Critical Current

Links

JP2024560676A 2022-04-15 2023-04-14 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用 Pending JP2025512469A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263331716P 2022-04-15 2022-04-15
US63/331,716 2022-04-15
PCT/US2023/065764 WO2023201324A1 (en) 2022-04-15 2023-04-14 Muscle targeting complexes and uses thereof for treating myotonic dystrophy

Publications (2)

Publication Number Publication Date
JP2025512469A JP2025512469A (ja) 2025-04-17
JP2025512469A5 true JP2025512469A5 (enExample) 2026-02-02

Family

ID=88330384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560676A Pending JP2025512469A (ja) 2022-04-15 2023-04-14 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用

Country Status (10)

Country Link
US (1) US20250249116A1 (enExample)
EP (1) EP4508091A1 (enExample)
JP (1) JP2025512469A (enExample)
KR (1) KR20250004769A (enExample)
CN (1) CN119256008A (enExample)
AU (1) AU2023253710A1 (enExample)
CA (1) CA3248961A1 (enExample)
IL (1) IL315944A (enExample)
MX (1) MX2024012737A (enExample)
WO (1) WO2023201324A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
WO2020028832A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
EP3830259A4 (en) 2018-08-02 2022-05-04 Dyne Therapeutics, Inc. MUSCLE TARGETED COMPLEXES AND THEIR USES IN THE TREATMENT OF FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
WO2021154477A1 (en) 2020-01-31 2021-08-05 Dyne Therapeutics, Inc. Anti-transferrin receptor (tfr) antibody and uses thereof
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
WO2023283623A1 (en) 2021-07-09 2023-01-12 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating dystrophinopathies
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG186451A1 (en) * 2010-07-12 2013-01-30 Covx Technologies Ireland Ltd Multifunctional antibody conjugates
MX2023000958A (es) * 2020-07-23 2023-04-14 Dyne Therapeutics Inc Complejos dirigidos al musculo y usos de estos para el tratamiento de la distrofia miotonica.

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