JP2025511869A - 大環状ペプチド抗生物質の結晶形態 - Google Patents

大環状ペプチド抗生物質の結晶形態 Download PDF

Info

Publication number
JP2025511869A
JP2025511869A JP2024559427A JP2024559427A JP2025511869A JP 2025511869 A JP2025511869 A JP 2025511869A JP 2024559427 A JP2024559427 A JP 2024559427A JP 2024559427 A JP2024559427 A JP 2024559427A JP 2025511869 A JP2025511869 A JP 2025511869A
Authority
JP
Japan
Prior art keywords
xrpd
wavenumbers
crystalline
atr
ray powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024559427A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025511869A5 (enExample
Inventor
ディオドネ，ラルフ
エグリ，アンドレ
エンケルマン，デニス・ディモ
リンデマー，ミヒェル・ドミニク
シュタデルマン，バレンティン・アンドレアス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2025511869A publication Critical patent/JP2025511869A/ja
Publication of JP2025511869A5 publication Critical patent/JP2025511869A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024559427A 2022-04-07 2023-04-05 大環状ペプチド抗生物質の結晶形態 Pending JP2025511869A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22167057.3 2022-04-07
EP22167057 2022-04-07
PCT/EP2023/058906 WO2023194418A1 (en) 2022-04-07 2023-04-05 Crystalline forms of a macrocyclic peptide antibiotic

Publications (2)

Publication Number Publication Date
JP2025511869A true JP2025511869A (ja) 2025-04-16
JP2025511869A5 JP2025511869A5 (enExample) 2026-04-13

Family

ID=81448543

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024559427A Pending JP2025511869A (ja) 2022-04-07 2023-04-05 大環状ペプチド抗生物質の結晶形態

Country Status (10)

Country Link
EP (1) EP4504749A1 (enExample)
JP (1) JP2025511869A (enExample)
KR (1) KR20240169690A (enExample)
CN (1) CN118974073A (enExample)
AU (1) AU2023250008A1 (enExample)
CA (1) CA3255726A1 (enExample)
IL (1) IL315686A (enExample)
MX (1) MX2024012228A (enExample)
TW (1) TW202404991A (enExample)
WO (1) WO2023194418A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026154152A1 (en) * 2025-01-20 2026-07-23 F. Hoffmann-La Roche Ag Pharmaceutical compositions comprising an antibiotic macrocyclic peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11819532B2 (en) 2018-04-23 2023-11-21 Hoffmann-La Roche Inc. Peptide macrocycles against Acinetobacter baumannii

Also Published As

Publication number Publication date
CN118974073A (zh) 2024-11-15
CA3255726A1 (en) 2023-10-12
EP4504749A1 (en) 2025-02-12
IL315686A (en) 2024-11-01
MX2024012228A (es) 2024-11-08
WO2023194418A1 (en) 2023-10-12
TW202404991A (zh) 2024-02-01
KR20240169690A (ko) 2024-12-03
AU2023250008A1 (en) 2024-10-03

Similar Documents

Publication Publication Date Title
CN101903371B (zh) N-(叔-丁氧基羰基)-3-甲基-l-缬氨酰-(4r)-4-((7-氯-4-甲氧基-1-异喹啉基)氧基)-n-((1r，2s)-1-((环丙基磺酰基)氨甲酰基)-2-乙烯基环丙基)-l-脯氨酰胺的晶型
JP5701246B2 (ja) 有機化合物
CN107056813B (zh) 德罗格韦钠盐的晶型及其制备方法
KR20240169690A (ko) 거대고리 펩티드 항생제의 결정질 형태
CA2881958C (en) Pharmaceutical formulations containing 3-(4-cinnamyl-1-piperazinyl) amino derivatives of 3-formylrifamycin sv and 3-formylrifamycin s and a process of their preparation
HK40114674A (en) Crystalline forms of a macrocyclic peptide antibiotic
CZ217694A3 (en) 3/2 hydrate and anhydrate of 7-/(7-(s)-amino-5-azaspiro/2.4/heptan-5-yl/-8-chloro-6-fluoro-1-/(1r,2s) 2-fluorocyclopropyl/-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, processes of selective production of 3/2 hydrate, crystals thereof and antibacterial agents based thereon
CN111094313B (zh) 盐酸伊达比星一水合物的晶型
AU2010277947A1 (en) R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl- 6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and L-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same for antimicrobial
CN114096522A (zh) 化合物的晶型和制备化合物的晶型的方法
HK1149754A (en) Process for purifying staurosporine

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260403

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20260403