CN118974073A - 大环肽抗生素的结晶形式 - Google Patents

大环肽抗生素的结晶形式 Download PDF

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Publication number
CN118974073A
CN118974073A CN202380032881.2A CN202380032881A CN118974073A CN 118974073 A CN118974073 A CN 118974073A CN 202380032881 A CN202380032881 A CN 202380032881A CN 118974073 A CN118974073 A CN 118974073A
Authority
CN
China
Prior art keywords
xrpd
crystalline
atr
ray powder
powder diffraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380032881.2A
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English (en)
Chinese (zh)
Inventor
R·迪奥多恩
A·埃格利
D·D·恩克尔曼
M·D·林德莫尔
V·A·施塔德尔曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN118974073A publication Critical patent/CN118974073A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN202380032881.2A 2022-04-07 2023-04-05 大环肽抗生素的结晶形式 Pending CN118974073A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22167057.3 2022-04-07
EP22167057 2022-04-07
PCT/EP2023/058906 WO2023194418A1 (en) 2022-04-07 2023-04-05 Crystalline forms of a macrocyclic peptide antibiotic

Publications (1)

Publication Number Publication Date
CN118974073A true CN118974073A (zh) 2024-11-15

Family

ID=81448543

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380032881.2A Pending CN118974073A (zh) 2022-04-07 2023-04-05 大环肽抗生素的结晶形式

Country Status (10)

Country Link
EP (1) EP4504749A1 (enExample)
JP (1) JP2025511869A (enExample)
KR (1) KR20240169690A (enExample)
CN (1) CN118974073A (enExample)
AU (1) AU2023250008A1 (enExample)
CA (1) CA3255726A1 (enExample)
IL (1) IL315686A (enExample)
MX (1) MX2024012228A (enExample)
TW (1) TW202404991A (enExample)
WO (1) WO2023194418A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026154152A1 (en) * 2025-01-20 2026-07-23 F. Hoffmann-La Roche Ag Pharmaceutical compositions comprising an antibiotic macrocyclic peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11819532B2 (en) 2018-04-23 2023-11-21 Hoffmann-La Roche Inc. Peptide macrocycles against Acinetobacter baumannii

Also Published As

Publication number Publication date
CA3255726A1 (en) 2023-10-12
EP4504749A1 (en) 2025-02-12
IL315686A (en) 2024-11-01
MX2024012228A (es) 2024-11-08
WO2023194418A1 (en) 2023-10-12
TW202404991A (zh) 2024-02-01
KR20240169690A (ko) 2024-12-03
AU2023250008A1 (en) 2024-10-03
JP2025511869A (ja) 2025-04-16

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