CA3255726A1 - CRYSTALLINE FORMS OF A MACROCYCLIC PEPTIDE ANTIBIOTIC - Google Patents

CRYSTALLINE FORMS OF A MACROCYCLIC PEPTIDE ANTIBIOTIC

Info

Publication number
CA3255726A1
CA3255726A1 CA3255726A CA3255726A CA3255726A1 CA 3255726 A1 CA3255726 A1 CA 3255726A1 CA 3255726 A CA3255726 A CA 3255726A CA 3255726 A CA3255726 A CA 3255726A CA 3255726 A1 CA3255726 A1 CA 3255726A1
Authority
CA
Canada
Prior art keywords
theta
wavenumbers
xrpd
absorption bands
atr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3255726A
Other languages
English (en)
French (fr)
Inventor
Ralph Diodone
André Egli
Dennis Dimo Enkelmann
Michel Dominik LINDEMER
Valentin Andreas STADELMANN
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA3255726A1 publication Critical patent/CA3255726A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3255726A 2022-04-07 2023-04-05 CRYSTALLINE FORMS OF A MACROCYCLIC PEPTIDE ANTIBIOTIC Pending CA3255726A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22167057.3 2022-04-07
EP22167057 2022-04-07
PCT/EP2023/058906 WO2023194418A1 (en) 2022-04-07 2023-04-05 Crystalline forms of a macrocyclic peptide antibiotic

Publications (1)

Publication Number Publication Date
CA3255726A1 true CA3255726A1 (en) 2023-10-12

Family

ID=81448543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3255726A Pending CA3255726A1 (en) 2022-04-07 2023-04-05 CRYSTALLINE FORMS OF A MACROCYCLIC PEPTIDE ANTIBIOTIC

Country Status (10)

Country Link
EP (1) EP4504749A1 (enExample)
JP (1) JP2025511869A (enExample)
KR (1) KR20240169690A (enExample)
CN (1) CN118974073A (enExample)
AU (1) AU2023250008A1 (enExample)
CA (1) CA3255726A1 (enExample)
IL (1) IL315686A (enExample)
MX (1) MX2024012228A (enExample)
TW (1) TW202404991A (enExample)
WO (1) WO2023194418A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026154152A1 (en) * 2025-01-20 2026-07-23 F. Hoffmann-La Roche Ag Pharmaceutical compositions comprising an antibiotic macrocyclic peptide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11819532B2 (en) 2018-04-23 2023-11-21 Hoffmann-La Roche Inc. Peptide macrocycles against Acinetobacter baumannii

Also Published As

Publication number Publication date
CN118974073A (zh) 2024-11-15
EP4504749A1 (en) 2025-02-12
IL315686A (en) 2024-11-01
MX2024012228A (es) 2024-11-08
WO2023194418A1 (en) 2023-10-12
TW202404991A (zh) 2024-02-01
KR20240169690A (ko) 2024-12-03
AU2023250008A1 (en) 2024-10-03
JP2025511869A (ja) 2025-04-16

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