JP2025510901A5 - - Google Patents

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Publication number
JP2025510901A5
JP2025510901A5 JP2024557148A JP2024557148A JP2025510901A5 JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5 JP 2024557148 A JP2024557148 A JP 2024557148A JP 2024557148 A JP2024557148 A JP 2024557148A JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5
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JP
Japan
Prior art keywords
nucleic acid
variant pro
pro region
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024557148A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025510901A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/065162 external-priority patent/WO2023192953A1/en
Publication of JP2025510901A publication Critical patent/JP2025510901A/ja
Publication of JP2025510901A5 publication Critical patent/JP2025510901A5/ja
Pending legal-status Critical Current

Links

JP2024557148A 2022-04-01 2023-03-30 グラム陽性細菌細胞におけるタンパク質産生を強化するプロ領域突然変異 Pending JP2025510901A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263326615P 2022-04-01 2022-04-01
US63/326,615 2022-04-01
PCT/US2023/065162 WO2023192953A1 (en) 2022-04-01 2023-03-30 Pro-region mutations enhancing protein production in gram-positive bacterial cells

Publications (2)

Publication Number Publication Date
JP2025510901A JP2025510901A (ja) 2025-04-15
JP2025510901A5 true JP2025510901A5 (https=) 2026-03-13

Family

ID=86227005

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557148A Pending JP2025510901A (ja) 2022-04-01 2023-03-30 グラム陽性細菌細胞におけるタンパク質産生を強化するプロ領域突然変異

Country Status (6)

Country Link
US (1) US20250223623A1 (https=)
EP (1) EP4504756A1 (https=)
JP (1) JP2025510901A (https=)
KR (1) KR20240167690A (https=)
CN (1) CN119213015A (https=)
WO (1) WO2023192953A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026030345A1 (en) * 2024-07-29 2026-02-05 Danisco Us Inc. Signal and pro-region sequence variants for enhanced protease production in bacillus cells
WO2026050315A1 (en) 2024-08-29 2026-03-05 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429950A (en) 1992-03-30 1995-07-04 Genencor International, Inc. Heterologous gene expression in bacillus subtilis: fusion approach
WO2002014490A2 (en) 2000-08-11 2002-02-21 Genencor International, Inc. Bacillus transformation, transformants and mutant libraries
DK1495128T3 (da) 2002-03-29 2014-08-11 Genencor Int Forstærket proteinekspression i Bacillus
EP2129779B2 (en) * 2007-03-12 2018-12-26 Danisco US Inc. Modified proteases
AR076312A1 (es) 2009-04-24 2011-06-01 Danisco Us Inc Proteasas con regiones pro modificadas
WO2016205710A1 (en) 2015-06-17 2016-12-22 Danisco Us Inc. Proteases with modified propeptide regions
KR20200047668A (ko) 2017-09-13 2020-05-07 다니스코 유에스 인크. 바실러스에서 증가된 단백질 생산을 위한 변형된 5'-비번역 영역(utr) 서열

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