JP2025510901A5 - - Google Patents
Info
- Publication number
- JP2025510901A5 JP2025510901A5 JP2024557148A JP2024557148A JP2025510901A5 JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5 JP 2024557148 A JP2024557148 A JP 2024557148A JP 2024557148 A JP2024557148 A JP 2024557148A JP 2025510901 A5 JP2025510901 A5 JP 2025510901A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- variant pro
- pro region
- amino acid
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263326615P | 2022-04-01 | 2022-04-01 | |
| US63/326,615 | 2022-04-01 | ||
| PCT/US2023/065162 WO2023192953A1 (en) | 2022-04-01 | 2023-03-30 | Pro-region mutations enhancing protein production in gram-positive bacterial cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025510901A JP2025510901A (ja) | 2025-04-15 |
| JP2025510901A5 true JP2025510901A5 (https=) | 2026-03-13 |
Family
ID=86227005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024557148A Pending JP2025510901A (ja) | 2022-04-01 | 2023-03-30 | グラム陽性細菌細胞におけるタンパク質産生を強化するプロ領域突然変異 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250223623A1 (https=) |
| EP (1) | EP4504756A1 (https=) |
| JP (1) | JP2025510901A (https=) |
| KR (1) | KR20240167690A (https=) |
| CN (1) | CN119213015A (https=) |
| WO (1) | WO2023192953A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026030345A1 (en) * | 2024-07-29 | 2026-02-05 | Danisco Us Inc. | Signal and pro-region sequence variants for enhanced protease production in bacillus cells |
| WO2026050315A1 (en) | 2024-08-29 | 2026-03-05 | Danisco Us Inc. | Subtilisin variants and methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5429950A (en) | 1992-03-30 | 1995-07-04 | Genencor International, Inc. | Heterologous gene expression in bacillus subtilis: fusion approach |
| WO2002014490A2 (en) | 2000-08-11 | 2002-02-21 | Genencor International, Inc. | Bacillus transformation, transformants and mutant libraries |
| DK1495128T3 (da) | 2002-03-29 | 2014-08-11 | Genencor Int | Forstærket proteinekspression i Bacillus |
| EP2129779B2 (en) * | 2007-03-12 | 2018-12-26 | Danisco US Inc. | Modified proteases |
| AR076312A1 (es) | 2009-04-24 | 2011-06-01 | Danisco Us Inc | Proteasas con regiones pro modificadas |
| WO2016205710A1 (en) | 2015-06-17 | 2016-12-22 | Danisco Us Inc. | Proteases with modified propeptide regions |
| KR20200047668A (ko) | 2017-09-13 | 2020-05-07 | 다니스코 유에스 인크. | 바실러스에서 증가된 단백질 생산을 위한 변형된 5'-비번역 영역(utr) 서열 |
-
2023
- 2023-03-30 EP EP23720024.1A patent/EP4504756A1/en active Pending
- 2023-03-30 JP JP2024557148A patent/JP2025510901A/ja active Pending
- 2023-03-30 WO PCT/US2023/065162 patent/WO2023192953A1/en not_active Ceased
- 2023-03-30 CN CN202380040804.1A patent/CN119213015A/zh active Pending
- 2023-03-30 KR KR1020247035890A patent/KR20240167690A/ko active Pending
- 2023-03-30 US US18/851,026 patent/US20250223623A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113366108B (zh) | 新颖启动子序列及其增强芽孢杆菌属细胞蛋白生产的方法 | |
| CN103898080B (zh) | 具有增加产率的支链淀粉酶变体 | |
| JP7605902B2 (ja) | 誘導基質の非存在下における糸状菌細胞内でのタンパク質の産生 | |
| JP7787077B2 (ja) | バチルス・リケニフォルミス(bacillus licheniformis)における強化したタンパク質産生のための組成物及び方法 | |
| US11299522B2 (en) | Method of producing proteins in filamentous fungi with decreased CLR2 activity | |
| JP2025510901A5 (https=) | ||
| JP2019528797A5 (https=) | ||
| CN111670244B (zh) | 突变的和遗传修饰的芽孢杆菌属细胞及其用于增加蛋白质产生的方法 | |
| KR102826031B1 (ko) | 향상된 단백질 생산 및 이의 방법 | |
| US10597429B2 (en) | Method of producing proteins in filamentous fungi with decreased CLR1 activity | |
| CN117881772A (zh) | 编码新型核酸酶的多核苷酸、其组合物及其从蛋白质制剂中消除dna的方法 | |
| CN114667350A (zh) | 包含蛋白质生产率提高表型的真菌菌株及其方法 | |
| JP7799621B2 (ja) | 糸状菌細胞におけるタンパク質産生の増強のための組成物及び方法 | |
| US20240376511A1 (en) | Compositions and methods for enhanced protein production in fungal cells | |
| US20250320512A1 (en) | Compositions and methods for enhanced protein production in fungal cells | |
| Yoshino-Yasuda et al. | Sequence analysis and heterologous expression of polygalacturonase gene (AspecA) from a shoyu koji mold, Aspergillus sojae KBN1340 | |
| JP2025537244A (ja) | タンパク質生産性が増強された表現型を含む糸状菌株及びその方法 | |
| CN118256493A (zh) | 增强受柠檬酸钠诱导的启动子的活性的核酸分子及其应用 |