JP2025509780A5 - - Google Patents

Info

Publication number
JP2025509780A5
JP2025509780A5 JP2024555210A JP2024555210A JP2025509780A5 JP 2025509780 A5 JP2025509780 A5 JP 2025509780A5 JP 2024555210 A JP2024555210 A JP 2024555210A JP 2024555210 A JP2024555210 A JP 2024555210A JP 2025509780 A5 JP2025509780 A5 JP 2025509780A5
Authority
JP
Japan
Prior art keywords
composition according
inhibitor
inhibitors
stem cells
combinations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024555210A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025509780A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/015644 external-priority patent/WO2023177919A1/en
Publication of JP2025509780A publication Critical patent/JP2025509780A/ja
Publication of JP2025509780A5 publication Critical patent/JP2025509780A5/ja
Pending legal-status Critical Current

Links

JP2024555210A 2022-03-18 2023-03-20 中脳ドーパミンニューロンのインビボ生存を改善するための方法及び組成物 Pending JP2025509780A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263321507P 2022-03-18 2022-03-18
US63/321,507 2022-03-18
PCT/US2023/015644 WO2023177919A1 (en) 2022-03-18 2023-03-20 Methods and compositions for improving in vivo survival of midbrain dopamine neurons

Publications (2)

Publication Number Publication Date
JP2025509780A JP2025509780A (ja) 2025-04-11
JP2025509780A5 true JP2025509780A5 (https=) 2026-04-14

Family

ID=88024262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024555210A Pending JP2025509780A (ja) 2022-03-18 2023-03-20 中脳ドーパミンニューロンのインビボ生存を改善するための方法及び組成物

Country Status (5)

Country Link
US (1) US20250017979A1 (https=)
EP (1) EP4493275A4 (https=)
JP (1) JP2025509780A (https=)
CA (1) CA3254712A1 (https=)
WO (1) WO2023177919A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3693455A1 (en) * 2011-11-04 2020-08-12 Memorial Sloan-Kettering Cancer Center Midbrain dopamine (da) neurons for engraftment
IL270835B2 (en) * 2017-06-12 2025-01-01 Sinai Health Sys Allograft tolerance without the need for systemic immunosuppression
WO2020097380A1 (en) * 2018-11-07 2020-05-14 Berg Llc Methods for treating parkinson's disease
CA3193273A1 (en) * 2020-08-27 2022-03-03 Enosi Therapeutics Corporation Methods and compositions to treat autoimmune diseases and cancer

Similar Documents

Publication Publication Date Title
US11760978B2 (en) Cell culture medium for culturing organoid, culture method, and organoid
US12428623B2 (en) Generation of midbrain-specific organoids from human pluripotent stem cells
JP6869554B2 (ja) ヒト下痢症ウイルスの感染・増殖培養用2dオルガノイド及びその使用
KR102679619B1 (ko) 중간뇌 도파민(mda) 뉴런의 시험관내 분화 방법
JP6494515B2 (ja) 幹細胞を1又は2以上の細胞系列に分化させる方法
JP2020501534A (ja) 結腸オルガノイドならびにその作製方法および使用方法
Humphreys et al. Optogenetic control of the BMP signaling pathway
CN112585262B (zh) 肠神经前体细胞的制造方法
CN115449506A (zh) 多能干细胞分化成肠中肠内胚层细胞
EP3974519A1 (en) Expansion culture method for cartilage or bone precursor cells
JP7682470B2 (ja) オルガノイドの製造方法
JP2024028791A (ja) 上皮細胞培養用培養容器及びその使用
CN116716236A (zh) 一种宫颈癌类器官的构建方法及应用
JP2025509780A5 (https=)
Qiao et al. SEPHS1 is dispensable for pluripotency maintenance but indispensable for cardiac differentiation in mouse embryonic stem cells
JP2024538786A (ja) 軟骨及び骨を産生する方法
US12344862B2 (en) Human intestinal epithelium model and method for preparing same
JP7620293B2 (ja) 脳オルガノイド及びその使用
US20220135950A1 (en) Human intestinal epithelium model and method for preparing same
CN111213057A (zh) 用于底板中脑多巴胺能祖细胞的单细胞蛋白质表达谱分析的方法
TW202600811A (zh) 生成內皮細胞的方法
Reich et al. Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling
Zhu et al. Early development of porcine parthenogenetic embryos and reduced expression of primed pluripotent marker genes under the effect of lysophosphatidic acid
CN117487743B (zh) 一种诱导鸡胚成纤维细胞为鸡多能干细胞的化学诱导剂及诱导方法
WO2023177919A1 (en) Methods and compositions for improving in vivo survival of midbrain dopamine neurons