JP2025507894A5 - - Google Patents
Info
- Publication number
- JP2025507894A5 JP2025507894A5 JP2024552144A JP2024552144A JP2025507894A5 JP 2025507894 A5 JP2025507894 A5 JP 2025507894A5 JP 2024552144 A JP2024552144 A JP 2024552144A JP 2024552144 A JP2024552144 A JP 2024552144A JP 2025507894 A5 JP2025507894 A5 JP 2025507894A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- mrna sequence
- independently
- motif
- ivt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263315323P | 2022-03-01 | 2022-03-01 | |
| US63/315,323 | 2022-03-01 | ||
| US202363485753P | 2023-02-17 | 2023-02-17 | |
| US63/485,753 | 2023-02-17 | ||
| PCT/US2023/014183 WO2023167880A2 (en) | 2022-03-01 | 2023-02-28 | Compositions and methods for capping rnas |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025507894A JP2025507894A (ja) | 2025-03-21 |
| JP2025507894A5 true JP2025507894A5 (enExample) | 2026-03-10 |
Family
ID=87884204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024552144A Pending JP2025507894A (ja) | 2022-03-01 | 2023-02-28 | Ｒｎａをキャッピングするための組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250084409A1 (enExample) |
| EP (1) | EP4486355A4 (enExample) |
| JP (1) | JP2025507894A (enExample) |
| CN (1) | CN119137271A (enExample) |
| WO (1) | WO2023167880A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN121311491A (zh) * | 2023-06-26 | 2026-01-09 | 埃洛诺瓦株式会社 | 新型修饰三核苷酸加帽衍生物以及引入加帽衍生物的mRNA |
| WO2025054401A2 (en) * | 2023-09-06 | 2025-03-13 | Trilink Biotechnologies, Llc | Cap analogs and methods of use thereof |
| CN116987137B (zh) * | 2023-09-26 | 2024-01-02 | 江苏申基生物科技有限公司 | 一种加帽化合物及其在mRNA加帽中的应用 |
| WO2025168058A1 (zh) * | 2024-02-08 | 2025-08-14 | 江苏申基生物科技有限公司 | 新的mRNA加帽化合物及其应用 |
| WO2026009929A1 (ja) * | 2024-07-03 | 2026-01-08 | 富士フイルム株式会社 | 化合物、ｒｎａ合成開始剤、およびそれらの利用 |
| CN119306779A (zh) * | 2024-12-13 | 2025-01-14 | 上海科泽永欣生物科技有限公司 | 一种含r构型的起始加帽寡核苷酸引物及其合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120842296A (zh) * | 2015-09-21 | 2025-10-28 | 垂林克生物技术有限公司 | 用于合成5’-加帽rna的组合物和方法 |
| WO2017066797A1 (en) * | 2015-10-16 | 2017-04-20 | Modernatx, Inc. | Trinucleotide mrna cap analogs |
| ES2763822T3 (es) * | 2015-12-09 | 2020-06-01 | Novartis Ag | Análisis exento de marcas de la eficacia de la adición de caperuzas al arn utilizando rnasa h, sondas y cromatografía líquida/espectrometría de masas |
| PL415967A1 (pl) * | 2016-01-29 | 2017-07-31 | Univ Warszawski | 5'-tiofosforanowe analogi końca 5' mRNA (kapu), sposób ich otrzymywania i zastosowanie |
| US10487105B2 (en) * | 2016-10-19 | 2019-11-26 | Arcturus Therapeutics, Inc. | Trinucleotide MRNA cap analogs |
| KR20200143391A (ko) * | 2018-03-15 | 2020-12-23 | 비온테크 알엔에이 파마슈티컬스 게엠베하 | 5'-캡-트리뉴클레오티드- 또는 고차의 올리고뉴클레오티드 화합물 및 이들의 rna 안정화, 단백질 발현 및 치료에서의 사용 |
| PL432884A1 (pl) * | 2020-02-12 | 2021-08-16 | Uniwersytet Warszawski | Nowe analogi kapu końca 5' mRNA, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA i peptydu |
| PL248416B1 (pl) * | 2020-02-12 | 2025-12-08 | Explorna Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia | Nowe analogi kapu końca 5’ mRNA, cząsteczka RNA je zawierająca, ich zastosowania i sposób syntezy cząsteczki RNA i peptydu |
| EP4208549A4 (en) * | 2020-09-04 | 2025-04-16 | Verve Therapeutics, Inc. | Compositions and methods for capping RNAs |
| US20250108066A1 (en) * | 2022-01-27 | 2025-04-03 | Trilink Biotechnologies, Llc | Trinucleotide cap analogs and methods of use thereof |
-
2023
- 2023-02-28 JP JP2024552144A patent/JP2025507894A/ja active Pending
- 2023-02-28 CN CN202380034551.7A patent/CN119137271A/zh active Pending
- 2023-02-28 EP EP23763863.0A patent/EP4486355A4/en active Pending
- 2023-02-28 WO PCT/US2023/014183 patent/WO2023167880A2/en not_active Ceased
-
2024
- 2024-11-25 US US18/819,275 patent/US20250084409A1/en active Pending
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