JP2025504984A - Covid後症状の治療における使用のためのイブジラスト - Google Patents

Covid後症状の治療における使用のためのイブジラスト Download PDF

Info

Publication number
JP2025504984A
JP2025504984A JP2024545781A JP2024545781A JP2025504984A JP 2025504984 A JP2025504984 A JP 2025504984A JP 2024545781 A JP2024545781 A JP 2024545781A JP 2024545781 A JP2024545781 A JP 2024545781A JP 2025504984 A JP2025504984 A JP 2025504984A
Authority
JP
Japan
Prior art keywords
day
ibudilast
pharma
acceptable salt
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024545781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504984A5 (https=
Inventor
和子 松田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicinova Inc
Original Assignee
Medicinova Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicinova Inc filed Critical Medicinova Inc
Publication of JP2025504984A publication Critical patent/JP2025504984A/ja
Publication of JP2025504984A5 publication Critical patent/JP2025504984A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024545781A 2022-02-01 2023-01-31 Covid後症状の治療における使用のためのイブジラスト Pending JP2025504984A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263305483P 2022-02-01 2022-02-01
US63/305,483 2022-02-01
PCT/US2023/011931 WO2023150093A1 (en) 2022-02-01 2023-01-31 Ibudilast for use in the treatment of post-covid conditions

Publications (2)

Publication Number Publication Date
JP2025504984A true JP2025504984A (ja) 2025-02-19
JP2025504984A5 JP2025504984A5 (https=) 2026-02-03

Family

ID=85382992

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024545781A Pending JP2025504984A (ja) 2022-02-01 2023-01-31 Covid後症状の治療における使用のためのイブジラスト

Country Status (6)

Country Link
US (1) US12171752B2 (https=)
EP (1) EP4472631A1 (https=)
JP (1) JP2025504984A (https=)
CN (1) CN118973574A (https=)
CA (1) CA3251194A1 (https=)
WO (1) WO2023150093A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12005049B2 (en) 2021-07-26 2024-06-11 Medicinova, Inc. Methods of preventing cancer metastasis
US12042485B2 (en) 2021-10-07 2024-07-23 Medicinova, Inc. Methods of minimizing cancer metastasis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395747B1 (en) 1998-08-10 2002-05-28 Sauro Sakoda Remedies for multiple sclerosis
JP4954085B2 (ja) 2004-12-06 2012-06-13 メディシノバ, インコーポレイテッド 神経障害性疼痛及びその関連する症状を治療するためのイブジラスト
US20090197823A1 (en) 2006-05-09 2009-08-06 Braincells, Inc. Aliskiren modulation of neurogenesis
WO2007142924A1 (en) 2006-05-31 2007-12-13 Avigen, Inc. Ibudilast for inhibiting macrophage migration inhibitory factor (mif) activity
US8138201B2 (en) 2007-07-11 2012-03-20 Medicinova, Inc. Treatment of progressive neurodegenerative disease with ibudilast
CA3174413A1 (en) 2020-04-06 2021-10-14 Yuichi Iwaki Methods of reducing plasma level of macrophage migratory inhibitory factor in patients with ibudilast
GB202005890D0 (en) * 2020-04-22 2020-06-03 Aivivo Ltd New uses
WO2022181219A1 (ja) 2021-02-24 2022-09-01 国立大学法人九州大学 新興ウイルス感染症治療薬

Also Published As

Publication number Publication date
EP4472631A1 (en) 2024-12-11
CN118973574A (zh) 2024-11-15
WO2023150093A1 (en) 2023-08-10
US12171752B2 (en) 2024-12-24
US20230285367A1 (en) 2023-09-14
CA3251194A1 (en) 2023-08-10

Similar Documents

Publication Publication Date Title
CN101848712B (zh) 用异丁地特治疗渐进性神经变性疾病
US12171752B2 (en) Methods of treating post-COVID condition(s)
KR20190073365A (ko) 사이토카인 과분비 및 바이러스성 감염의 치료를 위한 비만 세포 안정화제
JP6177765B2 (ja) 肺動脈性高血圧症の治療のためのfk506の利用
JP2010506904A (ja) 精神障害の治療における抗精神病薬およびテトラサイクリンの併用療法
JP2021512921A (ja) 癌療法に対するイブジラストおよび第二の薬剤を使用した方法ならびに投与レジメン
US20210177812A1 (en) Methods of suppressing myeloid-derived suppressor cells in patients
JP7652763B2 (ja) イブジラスト経口製剤およびその使用方法
US20230090534A1 (en) Methods of treating glioblastoma multiforme using combination therapy
US12005049B2 (en) Methods of preventing cancer metastasis
US20220241252A1 (en) Methods of treating chemical gas exposure
JP7430719B2 (ja) イブジラストを用いて眼疾患/障害または損傷を治療する方法
US10946071B2 (en) Combination of ibudilast and interferon-beta and methods of using same
SK7592002A3 (en) Method and compositions for treating pulmonary diseases
US12042485B2 (en) Methods of minimizing cancer metastasis
US20250288561A1 (en) Nezulcitinib for delivery by nebulized oral inhalation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260126

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20260126