JP2025106309A5 - - Google Patents

Info

Publication number
JP2025106309A5
JP2025106309A5 JP2025046395A JP2025046395A JP2025106309A5 JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5 JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5
Authority
JP
Japan
Prior art keywords
composition
car
subject
cells
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025046395A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025106309A (ja
Filing date
Publication date
Priority claimed from JP2021563033A external-priority patent/JP2022529380A/ja
Application filed filed Critical
Publication of JP2025106309A publication Critical patent/JP2025106309A/ja
Publication of JP2025106309A5 publication Critical patent/JP2025106309A5/ja
Pending legal-status Critical Current

Links

JP2025046395A 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用 Pending JP2025106309A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962839175P 2019-04-26 2019-04-26
US62/839,175 2019-04-26
JP2021563033A JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用
PCT/US2020/029768 WO2020219843A1 (en) 2019-04-26 2020-04-24 Chimeric antigen receptor constructs and their use in car-t cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021563033A Division JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Publications (2)

Publication Number Publication Date
JP2025106309A JP2025106309A (ja) 2025-07-15
JP2025106309A5 true JP2025106309A5 (enExample) 2025-10-27

Family

ID=72941305

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用
JP2025046395A Pending JP2025106309A (ja) 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Country Status (5)

Country Link
US (1) US12479890B2 (enExample)
EP (1) EP3959236A4 (enExample)
JP (2) JP2022529380A (enExample)
CN (1) CN114269777A (enExample)
WO (1) WO2020219843A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110225760B (zh) * 2016-09-15 2023-11-07 埃里西拉医疗公司 T细胞免疫疗法
US20230089392A1 (en) * 2021-09-20 2023-03-23 Immatics US, Inc. Monocyte depletion of t cells populations for t-cell therapy
EP4589005A1 (en) * 2022-09-13 2025-07-23 Cyto-Facto Inc. T cells for transplantation and production method thereof
WO2024236547A1 (en) * 2023-05-18 2024-11-21 Inceptor Bio, Llc Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
WO2026047626A1 (en) * 2024-08-30 2026-03-05 Inceptor Bio, Llc Compositions and methods involving immune cells engineered for binding bispecific antibodies for use in cell therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170241877A1 (en) * 2002-03-11 2017-08-24 Janusz B. Pawliszyn System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
US10246505B2 (en) * 2013-11-25 2019-04-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors to control HIV infection
WO2015092024A2 (en) 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
CN122399016A (zh) 2014-03-15 2026-07-17 诺华股份有限公司 使用嵌合抗原受体治疗癌症
US10577417B2 (en) * 2014-09-17 2020-03-03 Novartis Ag Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
RU2756247C2 (ru) 2014-11-17 2021-09-28 Эдисет Био, Инк. Генетически модифицированные гамма дельта т-клетки
RU2017125531A (ru) * 2014-12-19 2019-01-21 Дана-Фарбер Кэнсер Инститьют, Инк. Химерные антигенные рецепторы и способы их применения
CA2999070A1 (en) * 2015-09-17 2017-03-23 Novartis Ag Car t cell therapies with enhanced efficacy
MX2018008416A (es) * 2016-01-08 2019-11-11 Univ California Polipéptidos heterodímericos condicionalmente activos y métodos para su uso.
SG11201807489PA (en) 2016-03-04 2018-09-27 Novartis Ag Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
WO2017172952A1 (en) * 2016-04-01 2017-10-05 Promab Biotechnologies, Inc. Flag tagged cd19-car-t cells
EP3336107A1 (en) * 2016-12-15 2018-06-20 Miltenyi Biotec GmbH Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor
SG10202107808SA (en) * 2017-01-18 2021-08-30 F1 Oncology Inc Chimeric antigen receptors against axl or ror2 and methods of use thereof
CN110615842B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含共刺激受体的嵌合抗原受体及应用

Similar Documents

Publication Publication Date Title
EP4083073A1 (en) Novel chimeric antigen receptor and use thereof
JP7222600B2 (ja) 腫瘍細胞に特異的なキメラ抗原レセプター
JP2022529380A5 (enExample)
US20250136697A1 (en) Methods and compositions comprising b7h3 chimeric antigen receptors
CN112912401B (zh) 抗-l1细胞粘附分子抗体或其抗原结合片段及包含其的嵌合抗原受体
CN115403671B (zh) 靶向Claudin18.2的纳米抗体及其用途
CN114401989A (zh) 靶向bcma的抗体及嵌合抗原受体
JP2022542559A5 (enExample)
JP2018528786A5 (enExample)
CN113717942A (zh) 一种联合嵌合抗原受体和i型干扰素的免疫治疗方法及其应用
CN110461881A (zh) 嵌合抗原受体
AU2023415250A1 (en) Antibody or antibody fragment targeting b7-h3, and use thereof in field of chimeric antigen receptor immune cell therapy
WO2023107593A2 (en) In vivo delivery to immune cells
WO2022148410A1 (zh) 抗pd-l1/抗4-1bb天然抗体结构样异源二聚体形式双特异抗体及其制备
CA3158047A1 (en) Bi-functional antibody against pd-l1 and tgf?
KR20250080888A (ko) 신규한 항메소텔린 키메라 항원 수용체 및 변형 면역 세포
JP2025513626A (ja) Ｃｉｉｔａ遺伝子がノックアウトされた操作された免疫細胞及びその用途
JP2022529380A (ja) キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用
US20240299543A1 (en) Self-polarizing immune cells
US20230270858A1 (en) Novel co-stimulatory domain and use thereof
Battin et al. Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents
KR102393776B1 (ko) Cd22에 특이적인 인간화 항체 및 이를 이용한 키메라 항원 수용체
CN117430712A (zh) 靶向cxcr6的嵌合抗原受体及其用途
CN115806628A (zh) 一种自分泌IL-15与anti-TIGIT结合的融合蛋白及其应用
CN115873115A (zh) 一种抗4-1bb单克隆抗体在肿瘤免疫治疗上的应用