JP2025081549A5 - - Google Patents
Info
- Publication number
- JP2025081549A5 JP2025081549A5 JP2025025886A JP2025025886A JP2025081549A5 JP 2025081549 A5 JP2025081549 A5 JP 2025081549A5 JP 2025025886 A JP2025025886 A JP 2025025886A JP 2025025886 A JP2025025886 A JP 2025025886A JP 2025081549 A5 JP2025081549 A5 JP 2025081549A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- amino acid
- light chain
- chimeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962874287P | 2019-07-15 | 2019-07-15 | |
| US62/874,287 | 2019-07-15 | ||
| JP2022502245A JP7695228B2 (ja) | 2019-07-15 | 2020-07-15 | ヒト及びイヌctla-4に対するイヌ化抗体 |
| PCT/EP2020/069924 WO2021009188A1 (en) | 2019-07-15 | 2020-07-15 | Caninized antibodies to human and canine ctla-4 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502245A Division JP7695228B2 (ja) | 2019-07-15 | 2020-07-15 | ヒト及びイヌctla-4に対するイヌ化抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025081549A JP2025081549A (ja) | 2025-05-27 |
| JP2025081549A5 true JP2025081549A5 (https=) | 2025-10-10 |
Family
ID=71620455
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502245A Active JP7695228B2 (ja) | 2019-07-15 | 2020-07-15 | ヒト及びイヌctla-4に対するイヌ化抗体 |
| JP2025025886A Pending JP2025081549A (ja) | 2019-07-15 | 2025-02-20 | ヒト及びイヌctla-4に対するイヌ化抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502245A Active JP7695228B2 (ja) | 2019-07-15 | 2020-07-15 | ヒト及びイヌctla-4に対するイヌ化抗体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12552864B2 (https=) |
| EP (1) | EP3999539A1 (https=) |
| JP (2) | JP7695228B2 (https=) |
| CN (2) | CN114174336B (https=) |
| AU (1) | AU2020312687A1 (https=) |
| BR (1) | BR112022000604A2 (https=) |
| CA (1) | CA3145347A1 (https=) |
| WO (1) | WO2021009188A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021009188A1 (en) * | 2019-07-15 | 2021-01-21 | Intervet International B.V. | Caninized antibodies to human and canine ctla-4 |
| US20240209096A1 (en) | 2022-12-27 | 2024-06-27 | Invetx, Inc. | Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use |
| AU2024210302A1 (en) | 2023-01-20 | 2025-09-04 | Invetx, Inc. | Bispecific binding agents for use in companion animals |
| CN120137035A (zh) * | 2023-12-06 | 2025-06-13 | 北京伟杰信生物科技有限公司 | 一种抗犬pd-1抗体及其用途 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| EP0216846B2 (en) | 1985-04-01 | 1995-04-26 | Celltech Limited | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| GB9818110D0 (en) | 1998-08-19 | 1998-10-14 | Weston Medical Ltd | Needleless injectors and other devices |
| US6096002A (en) | 1998-11-18 | 2000-08-01 | Bioject, Inc. | NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method |
| US6682736B1 (en) * | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
| CZ302706B6 (cs) | 1998-12-23 | 2011-09-14 | Pfizer Inc. | Lidská monoklonální protilátka, farmaceutická kompozice tuto protilátku obsahující, bunecná linie produkující tuto protilátku, izolovaná molekula kódující težký nebo lehký retezec uvedené protilátky, hostitelská bunka obsahující tuto izolovanou molek |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| EP1212422B1 (en) * | 1999-08-24 | 2007-02-21 | Medarex, Inc. | Human ctla-4 antibodies and their uses |
| US6703360B2 (en) * | 2000-04-07 | 2004-03-09 | Heska Corporation | Compositions and methods related to canine IgG and canine IL-13 receptors |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| US7261890B2 (en) * | 2001-12-21 | 2007-08-28 | Idexx Laboratories, Inc. | Methods for using canine immunoglobulin variable domains and caninized antibodies |
| BRPI0509274A (pt) | 2004-03-26 | 2007-09-04 | Pfizer Prod Inc | usos de anticorpos anti-ctla-4 |
| PL2108132T3 (pl) * | 2007-01-15 | 2018-08-31 | Rapiscan Systems, Inc. | Systemy wykrywające |
| GB0903325D0 (en) | 2009-02-26 | 2009-04-08 | Univ Aberdeen | Antibody molecules |
| CA2754408A1 (en) | 2009-03-30 | 2010-10-14 | Boehringer Ingelheim International Gmbh | Fusion proteins comprising canine fc portions |
| US9616120B2 (en) * | 2010-03-04 | 2017-04-11 | Vet Therapeutics, Inc. | Monoclonal antibodies directed to CD20 |
| GB201103955D0 (en) | 2011-03-09 | 2011-04-20 | Antitope Ltd | Antibodies |
| US8790651B2 (en) * | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
| WO2013054127A1 (en) * | 2011-10-13 | 2013-04-18 | Nvip Pty Ltd | Canine/feline cd20 binding epitope and compositions for binding thereto |
| CA2875783C (en) | 2012-06-06 | 2018-12-11 | Zoetis Llc | Caninized anti-ngf antibodies and methods thereof |
| CN106029697B (zh) | 2013-12-20 | 2021-06-04 | 英特维特国际股份有限公司 | 具有经修饰的ch2-ch3序列的犬抗体 |
| CN107074952B (zh) | 2014-09-30 | 2021-04-09 | 英特维特国际股份有限公司 | 结合犬pd-l1的pd-l1抗体 |
| CA2980087A1 (en) * | 2015-04-02 | 2016-10-06 | Intervet International B.V. | Antibodies to canine interleukin-4 receptor alpha |
| WO2017062615A2 (en) | 2015-10-08 | 2017-04-13 | Macrogenics, Inc. | Combination therapy for the treatment of cancer |
| IL260021B (en) * | 2015-12-14 | 2022-09-01 | Macrogenics Inc | Bispecific molecules that are immunoreactive for pd1 and ctla4 and methods for using them |
| CA3005696A1 (en) | 2015-12-18 | 2017-06-22 | Intervet International B.V. | Caninized human antibodies to human and canine il-4r alpha |
| NL2017270B1 (en) | 2016-08-02 | 2018-02-09 | Aduro Biotech Holdings Europe B V | New anti-hCTLA-4 antibodies |
| WO2018037092A1 (en) * | 2016-08-26 | 2018-03-01 | Sanofi | Multispecific antibodies facilitating selective light chain pairing |
| JP2022500037A (ja) * | 2018-09-14 | 2022-01-04 | キンドレッド バイオサイエンシズ インコーポレイテッド | 獣医学的使用のための抗il4受容体抗体 |
| WO2021009188A1 (en) * | 2019-07-15 | 2021-01-21 | Intervet International B.V. | Caninized antibodies to human and canine ctla-4 |
-
2020
- 2020-07-15 WO PCT/EP2020/069924 patent/WO2021009188A1/en not_active Ceased
- 2020-07-15 BR BR112022000604A patent/BR112022000604A2/pt unknown
- 2020-07-15 CN CN202080050832.8A patent/CN114174336B/zh active Active
- 2020-07-15 US US17/626,242 patent/US12552864B2/en active Active
- 2020-07-15 JP JP2022502245A patent/JP7695228B2/ja active Active
- 2020-07-15 AU AU2020312687A patent/AU2020312687A1/en active Pending
- 2020-07-15 EP EP20740613.3A patent/EP3999539A1/en active Pending
- 2020-07-15 CN CN202411315030.1A patent/CN119307505A/zh active Pending
- 2020-07-15 CA CA3145347A patent/CA3145347A1/en active Pending
-
2025
- 2025-02-20 JP JP2025025886A patent/JP2025081549A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025081549A5 (https=) | ||
| AU2018203170B2 (en) | Multimeric Fusion Protein Vaccine And Immunotherapeutic | |
| US7786269B2 (en) | Antibody to latent membrane proteins and uses thereof | |
| JP2021524270A5 (https=) | ||
| JP2025109759A5 (https=) | ||
| EP3048115B1 (en) | Monoclonal antibodies for ebola and marburg viruses | |
| JP2021524275A5 (https=) | ||
| JP2022505445A5 (https=) | ||
| CN102690789B (zh) | 分泌破伤风外毒素单克隆抗体的杂交瘤细胞株及由其制备的单克隆抗体、Fab抗体与应用 | |
| JP2026510999A (ja) | Cd19/cd38多重特異性抗体 | |
| CN115461078A (zh) | 通过与改变的Fc片段形成融合蛋白增强蛋白/肽抗原免疫原性的方法 | |
| EP4628095A1 (en) | Fusion protein and granulated antigen comprising same | |
| CN117903301A (zh) | 特异性结合轮状病毒的抗体或其抗原结合片段 | |
| WO2014043215A1 (en) | Bi-specifc diabodies for masking and targeting vaccines | |
| CN113549147B (zh) | 抗柯萨奇a6型病毒的单克隆抗体及其应用 | |
| CA2539172C (fr) | Procede a haut rendement pour l'obtention d'anticorps humains neutralisant l'activite biologique d'une cytokine humaine | |
| CN102558306B (zh) | 旋毛虫副肌球蛋白b细胞抗原表位、其组合物及用途 | |
| JPWO2020071554A5 (https=) | ||
| CN118085082A (zh) | 抗猫TNF-α单克隆抗体及其应用 | |
| CN116444665A (zh) | 针对新冠病毒SARS-CoV-2糖蛋白RBD区域的单克隆抗体及其应用 | |
| WO2008107641A1 (en) | Liposome preparation | |
| JP6756950B2 (ja) | ヒトヘルペスウイルス6b抗原組成物 | |
| CN120904320B (zh) | 一种牙鲆弹状病毒重组单链可变区抗体及其应用 | |
| JP5435539B2 (ja) | 抗体産生細胞の活性化ペプチド | |
| RU2024118310A (ru) | Канинизированные антитела против человеческого ctla-4 |