JP2024546763A - イヌインターロイキン－３１受容体アルファｉに対するイヌ化抗体 - Google Patents

イヌインターロイキン－３１受容体アルファｉに対するイヌ化抗体 Download PDF

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JP2024546763A
JP2024546763A JP2024534474A JP2024534474A JP2024546763A JP 2024546763 A JP2024546763 A JP 2024546763A JP 2024534474 A JP2024534474 A JP 2024534474A JP 2024534474 A JP2024534474 A JP 2024534474A JP 2024546763 A JP2024546763 A JP 2024546763A
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seq
amino acid
acid sequence
antibody
canine
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JP2024534474A
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JP2024546763A5 (https=
Inventor
モーシー，モハマド
ジャン，ユアンジェン
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インターベット インターナショナル ベー． フェー．
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Publication of JP2024546763A5 publication Critical patent/JP2024546763A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024534474A 2021-12-16 2022-12-15 イヌインターロイキン－３１受容体アルファｉに対するイヌ化抗体 Pending JP2024546763A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163290256P 2021-12-16 2021-12-16
US202163290259P 2021-12-16 2021-12-16
US63/290,259 2021-12-16
US63/290,256 2021-12-16
US202263341443P 2022-05-13 2022-05-13
US63/341,443 2022-05-13
PCT/EP2022/086084 WO2023111148A1 (en) 2021-12-16 2022-12-15 Caninized antibodies to canine interleukin-31 receptor alpha 1

Publications (2)

Publication Number Publication Date
JP2024546763A true JP2024546763A (ja) 2024-12-26
JP2024546763A5 JP2024546763A5 (https=) 2025-12-19

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ID=84923386

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2024534474A Pending JP2024546763A (ja) 2021-12-16 2022-12-15 イヌインターロイキン－３１受容体アルファｉに対するイヌ化抗体
JP2024534465A Pending JP2024546759A (ja) 2021-12-16 2022-12-15 イヌインターロイキン－３１受容体アルファｉｉに対するイヌ化抗体

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JP2024534465A Pending JP2024546759A (ja) 2021-12-16 2022-12-15 イヌインターロイキン－３１受容体アルファｉｉに対するイヌ化抗体

Country Status (7)

Country Link
US (2) US20250340653A1 (https=)
EP (2) EP4448572A1 (https=)
JP (2) JP2024546763A (https=)
AU (2) AU2022409603A1 (https=)
CA (2) CA3239826A1 (https=)
MX (2) MX2024007090A (https=)
WO (2) WO2023111148A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4208157A1 (en) 2020-09-04 2023-07-12 Elanco Us Inc. Palatable formulations
WO2025174998A1 (en) * 2024-02-13 2025-08-21 Invetx, Inc. Anti-il-31ra antibodies and uses thereof

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US7696222B2 (en) 2005-08-12 2010-04-13 Merck Frosst Canada Ltd Indole derivatives as CRTH2 receptor antagonists
KR101335843B1 (ko) 2008-08-20 2013-12-02 조에티스 엘엘씨 피롤로[2,3-ｄ]피리미딘 화합물
WO2010031182A1 (en) 2008-09-22 2010-03-25 Merck Frosst Canada Ltd. Indole derivatives as crth2 receptor antagonists
CA2736571A1 (en) 2008-09-22 2010-03-25 Merck Frosst Canada Ltd. Azaindole derivatives as crth2 receptor antagonists
KR101445012B1 (ko) 2009-12-17 2014-09-26 머크 샤프 앤드 돔 코포레이션 Ｓｙｋ 억제제로서의 아미노피리미딘
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
CN106029697B (zh) 2013-12-20 2021-06-04 英特维特国际股份有限公司 具有经修饰的ch2-ch3序列的犬抗体
US20200181258A1 (en) * 2016-10-17 2020-06-11 Vetoquinol Sa Modified antibody constant region
JP7116063B2 (ja) 2016-12-14 2022-08-09 インターベット インターナショナル ベー． フェー． 選択的ヤヌスキナーゼ阻害剤としてのアミノピラゾール類
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Also Published As

Publication number Publication date
EP4448571A1 (en) 2024-10-23
MX2024007090A (es) 2024-08-22
CA3239826A1 (en) 2023-06-22
US20250340654A1 (en) 2025-11-06
US20250340653A1 (en) 2025-11-06
WO2023111148A1 (en) 2023-06-22
AU2022409610A1 (en) 2024-05-30
EP4448572A1 (en) 2024-10-23
WO2023111128A1 (en) 2023-06-22
JP2024546759A (ja) 2024-12-26
MX2024007089A (es) 2024-08-22
AU2022409603A1 (en) 2024-06-27
CA3239307A1 (en) 2023-06-22

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