JP2024546107A5 - - Google Patents

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Publication number
JP2024546107A5
JP2024546107A5 JP2024534260A JP2024534260A JP2024546107A5 JP 2024546107 A5 JP2024546107 A5 JP 2024546107A5 JP 2024534260 A JP2024534260 A JP 2024534260A JP 2024534260 A JP2024534260 A JP 2024534260A JP 2024546107 A5 JP2024546107 A5 JP 2024546107A5
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JP
Japan
Prior art keywords
group
optionally substituted
alkyl
cyano
occurrence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024534260A
Other languages
English (en)
Japanese (ja)
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JP2024546107A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/081236 external-priority patent/WO2023108103A1/en
Publication of JP2024546107A publication Critical patent/JP2024546107A/ja
Publication of JP2024546107A5 publication Critical patent/JP2024546107A5/ja
Pending legal-status Critical Current

Links

JP2024534260A 2021-12-09 2022-12-09 Rafキナーゼ阻害剤及びその使用方法 Pending JP2024546107A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163287866P 2021-12-09 2021-12-09
US63/287,866 2021-12-09
US202263393440P 2022-07-29 2022-07-29
US63/393,440 2022-07-29
PCT/US2022/081236 WO2023108103A1 (en) 2021-12-09 2022-12-09 Raf kinase inhibitors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024546107A JP2024546107A (ja) 2024-12-17
JP2024546107A5 true JP2024546107A5 (enExample) 2025-12-16

Family

ID=85018968

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024534260A Pending JP2024546107A (ja) 2021-12-09 2022-12-09 Rafキナーゼ阻害剤及びその使用方法

Country Status (8)

Country Link
US (1) US20230357179A1 (enExample)
EP (1) EP4444430A1 (enExample)
JP (1) JP2024546107A (enExample)
CN (1) CN119585242A (enExample)
AU (1) AU2022405115A1 (enExample)
CA (1) CA3240192A1 (enExample)
TW (1) TW202342442A (enExample)
WO (1) WO2023108103A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3746059B1 (en) 2018-01-31 2026-03-04 Deciphera Pharmaceuticals, LLC Combination therapy for the treatment of gastrointestinal stromal tumors
CN121419963A (zh) * 2023-06-13 2026-01-27 德西费拉制药有限责任公司 双重raf及微管蛋白抑制剂及其使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1505064A1 (en) * 2003-08-05 2005-02-09 Bayer HealthCare AG 2-Aminopyrimidine derivatives
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
US8906944B2 (en) * 2009-09-03 2014-12-09 Allergan, Inc. Compounds as tyrosine kinase modulators
AR090151A1 (es) 2012-03-07 2014-10-22 Lilly Co Eli Compuestos inhibidores de raf
WO2016038582A1 (en) * 2014-09-12 2016-03-17 Novartis Ag Compounds and compositions as raf kinase inhibitors
CN113874381A (zh) * 2019-03-22 2021-12-31 金耐特生物制药公司 Raf激酶的抑制剂
BR112022007612A2 (pt) * 2019-10-24 2022-09-20 Kinnate Biopharma Inc Inibidores de raf quinases
US11407737B2 (en) * 2020-09-18 2022-08-09 Kinnate Biopharma Inc. Inhibitors of RAF kinases

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