JP2024543481A5 - - Google Patents

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Publication number
JP2024543481A5
JP2024543481A5 JP2024528467A JP2024528467A JP2024543481A5 JP 2024543481 A5 JP2024543481 A5 JP 2024543481A5 JP 2024528467 A JP2024528467 A JP 2024528467A JP 2024528467 A JP2024528467 A JP 2024528467A JP 2024543481 A5 JP2024543481 A5 JP 2024543481A5
Authority
JP
Japan
Prior art keywords
nucleic acid
endonuclease
target nucleic
synthesized
nick
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024528467A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024543481A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/079567 external-priority patent/WO2023086834A1/en
Publication of JP2024543481A publication Critical patent/JP2024543481A/ja
Publication of JP2024543481A5 publication Critical patent/JP2024543481A5/ja
Pending legal-status Critical Current

Links

JP2024528467A 2021-11-12 2022-11-09 直接置き換えゲノム編集 Pending JP2024543481A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163278886P 2021-11-12 2021-11-12
US63/278,886 2021-11-12
US202263341200P 2022-05-12 2022-05-12
US63/341,200 2022-05-12
PCT/US2022/079567 WO2023086834A1 (en) 2021-11-12 2022-11-09 Direct replacement genome editing

Publications (2)

Publication Number Publication Date
JP2024543481A JP2024543481A (ja) 2024-11-21
JP2024543481A5 true JP2024543481A5 (https=) 2025-11-13

Family

ID=86324212

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024528467A Pending JP2024543481A (ja) 2021-11-12 2022-11-09 直接置き換えゲノム編集

Country Status (8)

Country Link
US (2) US20230151353A1 (https=)
EP (1) EP4430207A4 (https=)
JP (1) JP2024543481A (https=)
AU (1) AU2022387615A1 (https=)
CA (1) CA3237317A1 (https=)
IL (1) IL312727A (https=)
MX (1) MX2024005787A (https=)
WO (1) WO2023086834A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024233949A1 (en) * 2023-05-11 2024-11-14 Replace Therapeutics, Llc Revision of genetic material using direct replacement editing
AU2024347035A1 (en) * 2023-09-22 2026-04-02 Revision Bio Corporation Dna-dependent dna polymerase compositions, methods, and uses thereof
AU2024344127A1 (en) * 2023-09-22 2026-04-02 Revision Bio Corporation Dna ligase compositions, methods, and uses thereof
WO2025226730A1 (en) * 2024-04-22 2025-10-30 Transit Therapeutics, Inc. Revision of genetic material using direct replacement editing
WO2025235828A2 (en) * 2024-05-08 2025-11-13 The General Hospital Corporation Engineered prime editors for treating genetic deafness

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10221442B2 (en) * 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US20190330659A1 (en) * 2016-07-15 2019-10-31 Zymergen Inc. Scarless dna assembly and genome editing using crispr/cpf1 and dna ligase
US11649442B2 (en) * 2017-09-08 2023-05-16 The Regents Of The University Of California RNA-guided endonuclease fusion polypeptides and methods of use thereof
JP7663513B2 (ja) * 2019-05-16 2025-04-16 トラスティーズ オブ ボストン ユニバーシティ 調節された合成遺伝子発現システム
US20230008217A1 (en) * 2019-12-17 2023-01-12 Agilent Technologies, Inc. Ligation-based gene editing using crispr nickase
EP4081260A4 (en) * 2019-12-23 2024-01-17 The Broad Institute Inc. Programmable dna nuclease-associated ligase and methods of use thereof
JP2023518395A (ja) * 2020-03-19 2023-05-01 インテリア セラピューティクス,インコーポレイテッド 指向性ゲノム編集のための方法及び組成物

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