JP2024543217A - 多能性幹細胞から機能的膵島を生成する方法 - Google Patents

多能性幹細胞から機能的膵島を生成する方法 Download PDF

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JP2024543217A
JP2024543217A JP2024532849A JP2024532849A JP2024543217A JP 2024543217 A JP2024543217 A JP 2024543217A JP 2024532849 A JP2024532849 A JP 2024532849A JP 2024532849 A JP2024532849 A JP 2024532849A JP 2024543217 A JP2024543217 A JP 2024543217A
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cells
culture medium
inhibitor
hpsc
islets
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JP2024543217A5 (https=
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デン，ホンクイ
ドゥ，ユエンユエン
リアン，ジェン
ワン，シャオフェン
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Hangzhou Reprogenix Bioscience Inc
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Hangzhou Reprogenix Bioscience Inc
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JP2024532849A 2021-11-30 2021-11-30 多能性幹細胞から機能的膵島を生成する方法 Pending JP2024543217A (ja)

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PCT/CN2021/134632 WO2023097513A1 (en) 2021-11-30 2021-11-30 Method of generating functional islets from pluripotent stem cells

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JP2024543217A5 JP2024543217A5 (https=) 2024-12-09

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US (1) US20250002863A1 (https=)
EP (1) EP4440585A4 (https=)
JP (1) JP2024543217A (https=)
KR (1) KR20240146656A (https=)
CN (1) CN118355109A (https=)
AU (1) AU2021476471A1 (https=)
CA (1) CA3239460A1 (https=)
IL (1) IL313150A (https=)
WO (1) WO2023097513A1 (https=)

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Publication number Priority date Publication date Assignee Title
CN117511847A (zh) * 2023-11-06 2024-02-06 西安添易秦悦生物科技有限公司 一种自体诱导多能干细胞体外制备胰岛细胞团的方法
CN120158422B (zh) * 2025-05-20 2025-08-19 四川大学华西医院 一种共分化的血管化胰岛类器官及其构建方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019506153A (ja) * 2016-01-08 2019-03-07 マサチューセッツ インスティテュート オブ テクノロジー 分化した腸内分泌細胞およびインスリン産生細胞の作製
WO2020033879A1 (en) * 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
GB201216796D0 (en) * 2012-09-20 2012-11-07 Cambridge Entpr Ltd In vitro pancreatic differentiation
CN120796168A (zh) * 2013-06-11 2025-10-17 哈佛学院校长同事会 SC-β细胞以及用于产生其的组合物和方法
EP3411471B1 (en) * 2016-02-04 2021-01-06 Société des Produits Nestlé S.A. In vitro production of pancreatic beta cells
CN111246864A (zh) * 2017-07-21 2020-06-05 森玛治疗公司 干细胞衍生的胰腺β细胞的重聚
JP7646182B2 (ja) * 2018-05-16 2025-03-17 ワシントン・ユニバーシティ 内胚葉系統の細胞およびベータ細胞を生成するための方法および組成物、ならびにそれらの使用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019506153A (ja) * 2016-01-08 2019-03-07 マサチューセッツ インスティテュート オブ テクノロジー 分化した腸内分泌細胞およびインスリン産生細胞の作製
WO2020033879A1 (en) * 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation

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CN118355109A (zh) 2024-07-16
WO2023097513A1 (en) 2023-06-08
KR20240146656A (ko) 2024-10-08
EP4440585A4 (en) 2025-10-08
EP4440585A1 (en) 2024-10-09
IL313150A (en) 2024-07-01
AU2021476471A1 (en) 2024-06-20
CA3239460A1 (en) 2023-06-08
US20250002863A1 (en) 2025-01-02

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