JP2024542592A5 - - Google Patents

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Publication number
JP2024542592A5
JP2024542592A5 JP2024531425A JP2024531425A JP2024542592A5 JP 2024542592 A5 JP2024542592 A5 JP 2024542592A5 JP 2024531425 A JP2024531425 A JP 2024531425A JP 2024531425 A JP2024531425 A JP 2024531425A JP 2024542592 A5 JP2024542592 A5 JP 2024542592A5
Authority
JP
Japan
Prior art keywords
alkylene
pharmaceutically acceptable
binding group
alkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024531425A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542592A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/050952 external-priority patent/WO2023097038A1/en
Publication of JP2024542592A publication Critical patent/JP2024542592A/ja
Publication of JP2024542592A5 publication Critical patent/JP2024542592A5/ja
Pending legal-status Critical Current

Links

JP2024531425A 2021-11-26 2022-11-23 細胞表面受容体を標的とする開裂可能放射性リガンド及びその使用 Pending JP2024542592A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163283361P 2021-11-26 2021-11-26
US63/283,361 2021-11-26
PCT/US2022/050952 WO2023097038A1 (en) 2021-11-26 2022-11-23 Cleavable radioligands for targeting cell surface receptors and uses thereof

Publications (2)

Publication Number Publication Date
JP2024542592A JP2024542592A (ja) 2024-11-15
JP2024542592A5 true JP2024542592A5 (https=) 2025-11-27

Family

ID=86540347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024531425A Pending JP2024542592A (ja) 2021-11-26 2022-11-23 細胞表面受容体を標的とする開裂可能放射性リガンド及びその使用

Country Status (10)

Country Link
US (2) US12214059B2 (https=)
EP (1) EP4436979A1 (https=)
JP (1) JP2024542592A (https=)
KR (1) KR20240121775A (https=)
CN (1) CN118451091A (https=)
AU (1) AU2022397307A1 (https=)
CA (1) CA3238734A1 (https=)
CL (1) CL2024001560A1 (https=)
MX (1) MX2024005950A (https=)
WO (1) WO2023097038A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018204872A2 (en) * 2017-05-05 2018-11-08 Fusion Pharmaceuticals Inc. Igf-1r monoclonal antibodies and uses thereof
AU2022397307A1 (en) 2021-11-26 2024-06-06 Full-Life Technologies Uk Limited Cleavable radioligands for targeting cell surface receptors and uses thereof
WO2024126687A1 (en) * 2022-12-16 2024-06-20 Silence Therapeutics Gmbh Nucleic acids conjugated to an albumin binding moiety
CN121219017A (zh) * 2023-05-31 2025-12-26 辐联科技香港有限公司 缀合物及其用途
AU2024282578A1 (en) * 2023-05-31 2025-12-04 Full-Life Technologies Uk Limited Radioligands for targeting cell surface receptors and uses thereof
TW202540073A (zh) * 2023-11-30 2025-10-16 大陸商輻聯科技香港有限公司 靶向sstr受體的放射性化合物及其用途
CN118240015B (zh) * 2024-03-21 2025-03-21 中国科学院近代物理研究所 一种针对脑胶质瘤的靶向多肽及放射性示踪剂
WO2026002208A1 (zh) * 2024-06-28 2026-01-02 思路迪生物医药(上海)有限公司 前列腺特异性膜抗原小分子抑制剂及其放射性核素配合物的制备及应用
WO2026080432A1 (en) * 2024-10-07 2026-04-16 Beth Israel Deaconess Medical Center, Inc. Dimeric p-selectin inhibitors and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021556A (en) 1987-07-22 1991-06-04 Neorx Corporation Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides
US5075099A (en) 1988-05-31 1991-12-24 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US5364613A (en) 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5367080A (en) 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
US5886142A (en) 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
CA2721183C (en) * 2008-04-11 2019-07-16 Alnylam Pharmaceuticals, Inc. Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
EP3609541A4 (en) * 2017-04-05 2021-04-07 Cornell University Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies
CA3060143A1 (en) * 2017-05-24 2018-11-29 Itm Isotopen Technologien Munchen Ag Novel psma-binding agents and uses thereof
AU2022397307A1 (en) 2021-11-26 2024-06-06 Full-Life Technologies Uk Limited Cleavable radioligands for targeting cell surface receptors and uses thereof

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