JP2024542188A - 新規イオン化可能な脂質および脂質ナノ粒子ならびにそれらを使用する方法 - Google Patents

新規イオン化可能な脂質および脂質ナノ粒子ならびにそれらを使用する方法 Download PDF

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JP2024542188A
JP2024542188A JP2024529348A JP2024529348A JP2024542188A JP 2024542188 A JP2024542188 A JP 2024542188A JP 2024529348 A JP2024529348 A JP 2024529348A JP 2024529348 A JP2024529348 A JP 2024529348A JP 2024542188 A JP2024542188 A JP 2024542188A
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JPWO2023091490A5 (https=
JP2024542188A5 (https=
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アレッサンドラ バルトロッツィ
ジョン プラウドフット
ローマン エルトマン
シッダルト パテル
アライナ ハウ
ドミニク サレルノ
サンミット アディカリ
ローマン ボゴラード
アリジット アディカリ
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セイル バイオメディシンズ インコーポレイテッド
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    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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JP2024529348A 2021-11-16 2022-11-16 新規イオン化可能な脂質および脂質ナノ粒子ならびにそれらを使用する方法 Pending JP2024542188A (ja)

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CN (1) CN118829625A (https=)
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US12491261B2 (en) 2016-10-26 2025-12-09 Acuitas Therapeutics, Inc. Lipid nanoparticle formulations
JP7543259B2 (ja) 2018-10-18 2024-09-02 アクイタス セラピューティクス インコーポレイテッド 活性剤の脂質ナノ粒子送達のための脂質
WO2022016070A1 (en) 2020-07-16 2022-01-20 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
US12311033B2 (en) 2023-05-31 2025-05-27 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
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