JP2024541962A5 - - Google Patents

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Publication number
JP2024541962A5
JP2024541962A5 JP2024525211A JP2024525211A JP2024541962A5 JP 2024541962 A5 JP2024541962 A5 JP 2024541962A5 JP 2024525211 A JP2024525211 A JP 2024525211A JP 2024525211 A JP2024525211 A JP 2024525211A JP 2024541962 A5 JP2024541962 A5 JP 2024541962A5
Authority
JP
Japan
Application number
JP2024525211A
Other languages
Japanese (ja)
Other versions
JPWO2023081687A5 (https=
JP2024541962A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/079121 external-priority patent/WO2023081687A1/en
Publication of JP2024541962A publication Critical patent/JP2024541962A/ja
Publication of JPWO2023081687A5 publication Critical patent/JPWO2023081687A5/ja
Publication of JP2024541962A5 publication Critical patent/JP2024541962A5/ja
Pending legal-status Critical Current

Links

JP2024525211A 2021-11-03 2022-11-02 遺伝子編集のための修飾ガイドrna Pending JP2024541962A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163275426P 2021-11-03 2021-11-03
US63/275,426 2021-11-03
US202263352161P 2022-06-14 2022-06-14
US63/352,161 2022-06-14
PCT/US2022/079121 WO2023081687A1 (en) 2021-11-03 2022-11-02 Modified guide rnas for gene editing

Publications (3)

Publication Number Publication Date
JP2024541962A JP2024541962A (ja) 2024-11-13
JPWO2023081687A5 JPWO2023081687A5 (https=) 2026-02-26
JP2024541962A5 true JP2024541962A5 (https=) 2026-02-26

Family

ID=84820251

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525211A Pending JP2024541962A (ja) 2021-11-03 2022-11-02 遺伝子編集のための修飾ガイドrna

Country Status (12)

Country Link
US (1) US20240299583A1 (https=)
EP (1) EP4426836A1 (https=)
JP (1) JP2024541962A (https=)
KR (1) KR20240114295A (https=)
AU (1) AU2022381173A1 (https=)
CA (1) CA3236001A1 (https=)
CL (1) CL2024001330A1 (https=)
CO (1) CO2024006996A2 (https=)
IL (1) IL312507A (https=)
MX (1) MX2024005241A (https=)
TW (1) TW202334419A (https=)
WO (1) WO2023081687A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024324870A1 (en) 2023-08-14 2026-02-12 Intellia Therapeutics, Inc. Compositions and methods for genetically modifying transforming growth factor beta receptor type 2 (tgfβr2)
TW202521564A (zh) 2023-08-14 2025-06-01 美商英特利亞醫療公司 用於基於細胞之療法的cd70 car-t組合物及方法
TW202515994A (zh) 2023-08-14 2025-04-16 美商英特利亞醫療公司 用於對cd70進行基因修飾之組合物及方法
WO2025049481A1 (en) * 2023-08-28 2025-03-06 Intellia Therapeutics, Inc. Methods of editing an hla-a gene in vitro
WO2025049432A1 (en) * 2023-08-28 2025-03-06 Intellia Therapeutics, Inc. Methods for editing hla-a in cells pre-screened for the absence of one or both alleles of hla-h*01
TW202540417A (zh) 2023-11-10 2025-10-16 美商英特利亞醫療公司 用於基因體編輯之組合物、方法及系統
WO2025137301A1 (en) 2023-12-20 2025-06-26 Intellia Therapeutics, Inc. Methods for rapid engineering of cells
WO2025166323A2 (en) * 2024-02-02 2025-08-07 Editas Medicine, Inc. Crispr-related methods and compositions targeting lipoprotein (a) expression
WO2025255308A1 (en) 2024-06-07 2025-12-11 Intellia Therapeutics, Inc. Cd8 co-receptor chimeric polypeptides in tcr cell therapy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10900034B2 (en) * 2014-12-03 2021-01-26 Agilent Technologies, Inc. Guide RNA with chemical modifications
EP3159407A1 (en) * 2015-10-23 2017-04-26 Silence Therapeutics (London) Ltd Guide rnas, methods and uses
US11518994B2 (en) * 2016-01-30 2022-12-06 Bonac Corporation Artificial single guide RNA and use thereof
AU2017374044B2 (en) * 2016-12-08 2023-11-30 Intellia Therapeutics, Inc. Modified guide RNAs
AU2018364993B2 (en) * 2017-11-10 2022-10-06 University Of Massachusetts Targeted CRISPR delivery platforms
WO2019237069A1 (en) * 2018-06-08 2019-12-12 Intellia Therapeutics, Inc. Modified guide rnas for gene editing
EP3823633A4 (en) * 2018-06-29 2023-05-03 Editas Medicine, Inc. SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
MX2022006950A (es) * 2019-12-11 2022-11-07 Intellia Therapeutics Inc Arn guía modificados para edición de genes.
CR20230305A (es) * 2020-12-11 2023-11-10 Intellia Therapeutics Inc Polinucleótidos, composiciones y métodos para la edición del genoma que implican desaminación
KR20240032013A (ko) * 2021-06-10 2024-03-08 인텔리아 테라퓨틱스, 인크. 유전자 편집을 위한 내부 링커를 포함하는 변형된 가이드 rna

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