JP2024541962A5 - - Google Patents
Info
- Publication number
- JP2024541962A5 JP2024541962A5 JP2024525211A JP2024525211A JP2024541962A5 JP 2024541962 A5 JP2024541962 A5 JP 2024541962A5 JP 2024525211 A JP2024525211 A JP 2024525211A JP 2024525211 A JP2024525211 A JP 2024525211A JP 2024541962 A5 JP2024541962 A5 JP 2024541962A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotides
- region
- optionally
- nucleotide
- grna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163275426P | 2021-11-03 | 2021-11-03 | |
| US63/275,426 | 2021-11-03 | ||
| US202263352161P | 2022-06-14 | 2022-06-14 | |
| US63/352,161 | 2022-06-14 | ||
| PCT/US2022/079121 WO2023081687A1 (en) | 2021-11-03 | 2022-11-02 | Modified guide rnas for gene editing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024541962A JP2024541962A (ja) | 2024-11-13 |
| JP2024541962A5 true JP2024541962A5 (https=) | 2026-02-26 |
Family
ID=84820251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024525211A Pending JP2024541962A (ja) | 2021-11-03 | 2022-11-02 | 遺伝子編集のための修飾ガイドｒｎａ |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240299583A1 (https=) |
| EP (1) | EP4426836A1 (https=) |
| JP (1) | JP2024541962A (https=) |
| KR (1) | KR20240114295A (https=) |
| AU (1) | AU2022381173A1 (https=) |
| CA (1) | CA3236001A1 (https=) |
| CL (1) | CL2024001330A1 (https=) |
| CO (1) | CO2024006996A2 (https=) |
| IL (1) | IL312507A (https=) |
| MX (1) | MX2024005241A (https=) |
| TW (1) | TW202334419A (https=) |
| WO (1) | WO2023081687A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025038646A1 (en) | 2023-08-14 | 2025-02-20 | Intellia Therapeutics, Inc. | Cd70 car-t compositions and methods for cell-based therapy |
| WO2025038642A1 (en) | 2023-08-14 | 2025-02-20 | Intellia Therapeutics, Inc. | Compositions and methods for genetically modifying cd70 |
| IL326191A (en) | 2023-08-14 | 2026-03-01 | Intellia Therapeutics Inc | Compositions and methods for genetic modification of transforming growth factor beta receptor type 2 (tgfβr2) |
| WO2025049432A1 (en) * | 2023-08-28 | 2025-03-06 | Intellia Therapeutics, Inc. | Methods for editing hla-a in cells pre-screened for the absence of one or both alleles of hla-h*01 |
| WO2025049481A1 (en) * | 2023-08-28 | 2025-03-06 | Intellia Therapeutics, Inc. | Methods of editing an hla-a gene in vitro |
| WO2025101994A2 (en) | 2023-11-10 | 2025-05-15 | Intellia Therapeutics, Inc. | Compositions, methods, and systems for genomic editing |
| WO2025137301A1 (en) | 2023-12-20 | 2025-06-26 | Intellia Therapeutics, Inc. | Methods for rapid engineering of cells |
| WO2025166325A1 (en) * | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025255308A1 (en) | 2024-06-07 | 2025-12-11 | Intellia Therapeutics, Inc. | Cd8 co-receptor chimeric polypeptides in tcr cell therapy |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2969619A1 (en) * | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| EP3159407A1 (en) * | 2015-10-23 | 2017-04-26 | Silence Therapeutics (London) Ltd | Guide rnas, methods and uses |
| CN109072224B (zh) * | 2016-01-30 | 2022-07-15 | 株式会社博纳克 | 人工单导rna及其用途 |
| SG10202106058WA (en) * | 2016-12-08 | 2021-07-29 | Intellia Therapeutics Inc | Modified guide rnas |
| IL317505A (en) * | 2017-11-10 | 2025-02-01 | Univ Massachusetts | CRISPR-directed delivery platforms |
| AU2019282824C1 (en) * | 2018-06-08 | 2026-04-23 | Intellia Therapeutics, Inc. | Modified guide RNAS for gene editing |
| EP3823633A4 (en) * | 2018-06-29 | 2023-05-03 | Editas Medicine, Inc. | SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO |
| EP4073249A1 (en) * | 2019-12-11 | 2022-10-19 | Intellia Therapeutics, Inc. | Modified guide rnas for gene editing |
| IL303506A (en) * | 2020-12-11 | 2023-08-01 | Intellia Therapeutics Inc | Polynucleotides, compositions, and methods for genome editing involving deamination |
| WO2022261292A1 (en) * | 2021-06-10 | 2022-12-15 | Intellia Therapeutics, Inc. | Modified guide rnas comprising an internal linker for gene editing |
-
2022
- 2022-11-02 IL IL312507A patent/IL312507A/en unknown
- 2022-11-02 KR KR1020247018180A patent/KR20240114295A/ko active Pending
- 2022-11-02 AU AU2022381173A patent/AU2022381173A1/en active Pending
- 2022-11-02 JP JP2024525211A patent/JP2024541962A/ja active Pending
- 2022-11-02 TW TW111141866A patent/TW202334419A/zh unknown
- 2022-11-02 MX MX2024005241A patent/MX2024005241A/es unknown
- 2022-11-02 WO PCT/US2022/079121 patent/WO2023081687A1/en not_active Ceased
- 2022-11-02 CA CA3236001A patent/CA3236001A1/en active Pending
- 2022-11-02 EP EP22836372.7A patent/EP4426836A1/en active Pending
-
2024
- 2024-04-30 CL CL2024001330A patent/CL2024001330A1/es unknown
- 2024-05-01 US US18/652,176 patent/US20240299583A1/en active Pending
- 2024-05-31 CO CONC2024/0006996A patent/CO2024006996A2/es unknown
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