JP2024540187A - 三環式のヘテロ環 - Google Patents

三環式のヘテロ環 Download PDF

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Publication number
JP2024540187A
JP2024540187A JP2024525680A JP2024525680A JP2024540187A JP 2024540187 A JP2024540187 A JP 2024540187A JP 2024525680 A JP2024525680 A JP 2024525680A JP 2024525680 A JP2024525680 A JP 2024525680A JP 2024540187 A JP2024540187 A JP 2024540187A
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JP
Japan
Prior art keywords
substituted
unsubstituted
alkyl
independently
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525680A
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English (en)
Japanese (ja)
Other versions
JP2024540187A5 (https=
Inventor
ハインリッヒ，ティモ
シュレーシガー，サラー
グネラ，ヤークップ
パターソン，カール
ケッツナー，リサ
カルスウェル，エマ
ロペス，アンドレア アンズエ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Cancer Research Technology Ltd
Original Assignee
Merck Patent GmbH
Cancer Research Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH, Cancer Research Technology Ltd filed Critical Merck Patent GmbH
Publication of JP2024540187A publication Critical patent/JP2024540187A/ja
Publication of JP2024540187A5 publication Critical patent/JP2024540187A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2024525680A 2021-10-29 2022-10-26 三環式のヘテロ環 Pending JP2024540187A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21205456 2021-10-29
EP21205456.3 2021-10-29
PCT/EP2022/079848 WO2023072974A1 (en) 2021-10-29 2022-10-26 Tricyclic heterocycles

Publications (2)

Publication Number Publication Date
JP2024540187A true JP2024540187A (ja) 2024-10-31
JP2024540187A5 JP2024540187A5 (https=) 2025-10-31

Family

ID=78414452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525680A Pending JP2024540187A (ja) 2021-10-29 2022-10-26 三環式のヘテロ環

Country Status (7)

Country Link
EP (1) EP4423091A1 (https=)
JP (1) JP2024540187A (https=)
CN (1) CN118434743A (https=)
AU (1) AU2022378910A1 (https=)
CA (1) CA3236433A1 (https=)
IL (1) IL312303A (https=)
WO (1) WO2023072974A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119968359A (zh) 2022-09-29 2025-05-09 英矽智能科技知识产权有限公司 Tead抑制剂及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102079255B1 (ko) * 2013-06-18 2020-02-20 삼성디스플레이 주식회사 헤테로고리 화합물 및 이를 포함한 유기 발광 소자
WO2020096416A1 (ko) * 2018-11-09 2020-05-14 한국화학연구원 Yap-tead 결합을 저해하는 화합물 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약제학적 조성물
JP2023524863A (ja) * 2020-05-08 2023-06-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 三環式のヘテロ環

Also Published As

Publication number Publication date
AU2022378910A1 (en) 2024-06-13
CN118434743A (zh) 2024-08-02
EP4423091A1 (en) 2024-09-04
IL312303A (en) 2024-06-01
CA3236433A1 (en) 2023-05-04
WO2023072974A1 (en) 2023-05-04

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Legal Events

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A521 Request for written amendment filed

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Effective date: 20251023

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Effective date: 20251023