AU2022378910A1 - Tricyclic heterocycles - Google Patents

Tricyclic heterocycles Download PDF

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Publication number
AU2022378910A1
AU2022378910A1 AU2022378910A AU2022378910A AU2022378910A1 AU 2022378910 A1 AU2022378910 A1 AU 2022378910A1 AU 2022378910 A AU2022378910 A AU 2022378910A AU 2022378910 A AU2022378910 A AU 2022378910A AU 2022378910 A1 AU2022378910 A1 AU 2022378910A1
Authority
AU
Australia
Prior art keywords
substituted
alkyl
unsubstituted
ring
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022378910A
Other languages
English (en)
Inventor
Emma Carswell
Jakub GUNERA
Timo Heinrich
Lisa KOETZNER
Carl Petersson
Sarah SCHLESIGER
Andrea Unzue Lopez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Cancer Research Technology Ltd
Original Assignee
Merck Patent GmbH
Cancer Research Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH, Cancer Research Technology Ltd filed Critical Merck Patent GmbH
Publication of AU2022378910A1 publication Critical patent/AU2022378910A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2022378910A 2021-10-29 2022-10-26 Tricyclic heterocycles Pending AU2022378910A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21205456 2021-10-29
EP21205456.3 2021-10-29
PCT/EP2022/079848 WO2023072974A1 (en) 2021-10-29 2022-10-26 Tricyclic heterocycles

Publications (1)

Publication Number Publication Date
AU2022378910A1 true AU2022378910A1 (en) 2024-06-13

Family

ID=78414452

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022378910A Pending AU2022378910A1 (en) 2021-10-29 2022-10-26 Tricyclic heterocycles

Country Status (7)

Country Link
EP (1) EP4423091A1 (https=)
JP (1) JP2024540187A (https=)
CN (1) CN118434743A (https=)
AU (1) AU2022378910A1 (https=)
CA (1) CA3236433A1 (https=)
IL (1) IL312303A (https=)
WO (1) WO2023072974A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119968359A (zh) 2022-09-29 2025-05-09 英矽智能科技知识产权有限公司 Tead抑制剂及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102079255B1 (ko) * 2013-06-18 2020-02-20 삼성디스플레이 주식회사 헤테로고리 화합물 및 이를 포함한 유기 발광 소자
WO2020096416A1 (ko) * 2018-11-09 2020-05-14 한국화학연구원 Yap-tead 결합을 저해하는 화합물 및 이를 유효 성분으로 함유하는 암의 예방 또는 치료용 약제학적 조성물
JP2023524863A (ja) * 2020-05-08 2023-06-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 三環式のヘテロ環

Also Published As

Publication number Publication date
CN118434743A (zh) 2024-08-02
EP4423091A1 (en) 2024-09-04
JP2024540187A (ja) 2024-10-31
IL312303A (en) 2024-06-01
CA3236433A1 (en) 2023-05-04
WO2023072974A1 (en) 2023-05-04

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