JP2024539474A - 多剤耐性に関連付けられるvanA及び/又はvanB遺伝子を検出するための組成物及び方法 - Google Patents

多剤耐性に関連付けられるvanA及び/又はvanB遺伝子を検出するための組成物及び方法 Download PDF

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Publication number
JP2024539474A
JP2024539474A JP2024530466A JP2024530466A JP2024539474A JP 2024539474 A JP2024539474 A JP 2024539474A JP 2024530466 A JP2024530466 A JP 2024530466A JP 2024530466 A JP2024530466 A JP 2024530466A JP 2024539474 A JP2024539474 A JP 2024539474A
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Prior art keywords
seq
primer
oligonucleotide sequence
complement
vanb
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JP2024530466A
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Japanese (ja)
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JP2024539474A5 (cg-RX-API-DMAC10.html
Inventor
シー.キャディー カイル
チャン ライアン
ホー-チェン チウ シャロン
リン パトリック
モグハッダシ アッラシュ
スパイアー ユージーン
スン チンタオ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of JP2024539474A publication Critical patent/JP2024539474A/ja
Publication of JP2024539474A5 publication Critical patent/JP2024539474A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024530466A 2021-11-22 2022-11-21 多剤耐性に関連付けられるvanA及び/又はvanB遺伝子を検出するための組成物及び方法 Pending JP2024539474A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163264380P 2021-11-22 2021-11-22
US63/264,380 2021-11-22
PCT/EP2022/082684 WO2023089186A1 (en) 2021-11-22 2022-11-21 Compositions and methods for detecting vana and/or vanb genes associated with multidrug resistance

Publications (2)

Publication Number Publication Date
JP2024539474A true JP2024539474A (ja) 2024-10-28
JP2024539474A5 JP2024539474A5 (cg-RX-API-DMAC10.html) 2025-10-23

Family

ID=84487868

Family Applications (1)

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JP2024530466A Pending JP2024539474A (ja) 2021-11-22 2022-11-21 多剤耐性に関連付けられるvanA及び/又はvanB遺伝子を検出するための組成物及び方法

Country Status (5)

Country Link
US (1) US20250011882A1 (cg-RX-API-DMAC10.html)
EP (1) EP4437142A1 (cg-RX-API-DMAC10.html)
JP (1) JP2024539474A (cg-RX-API-DMAC10.html)
CN (1) CN118339315A (cg-RX-API-DMAC10.html)
WO (1) WO2023089186A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111433177B (zh) * 2017-12-04 2024-04-16 科慕埃弗西有限公司 用于制备1,1,3-三氯-4,4,4-三氟丁-1-烯和(e)-1,1,1,4,4,4-六氟丁-2-烯的方法和中间体
KR102714821B1 (ko) * 2023-07-27 2024-10-14 드림디엑스 주식회사 항생제 내성 세균 검출용 조성물 및 이를 이용한 검출방법

Family Cites Families (25)

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AU596068B2 (en) 1983-02-22 1990-04-26 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4996143A (en) 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5035996A (en) 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5683896A (en) 1989-06-01 1997-11-04 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP1067134B1 (en) 1991-11-07 2004-07-28 Nanotronics, Inc. Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
EP1442794B1 (en) 1996-06-04 2006-03-29 University Of Utah Research Foundation System and method for carrying out and monitoring biological processes
DE69739357D1 (de) 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
DK0866071T3 (da) 1997-03-20 2005-01-17 Hoffmann La Roche Modificerede primere
CA2348042A1 (en) 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
CA2624917C (en) 2005-10-05 2013-07-09 F. Hoffmann-La Roche Ag Non-fluorescent energy transfer
US7838221B2 (en) 2005-10-11 2010-11-23 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA)
US8535888B2 (en) 2006-12-29 2013-09-17 Mayo Foundation For Medical Education And Research Compositions and methods for detecting methicillin-resistant S. aureus
WO2012027302A2 (en) * 2010-08-21 2012-03-01 The Regents Of The University Of California Systems and methods for detecting antibiotic resistance
US9034581B2 (en) 2011-05-26 2015-05-19 Roche Molecular Systems, Inc. Compositions and methods for detection of Staphylococcus aureus
CA2894632A1 (en) * 2012-11-15 2014-05-22 Todd WALLACH Pcr reaction mixtures and methods of using same
CN106574295A (zh) * 2014-03-13 2017-04-19 奥普金公司 检测多重抗药性生物体的方法
US9920381B2 (en) 2014-12-02 2018-03-20 Roche Molecular Systems, Inc. Compositions and methods for detecting MECC-containing methicillin-resistant Staphylococcus aureus
EP4081666B1 (en) * 2019-12-27 2024-08-21 F. Hoffmann-La Roche AG Compositions and methods for detecting methicillin-resistant staphylococcus aureus

Also Published As

Publication number Publication date
US20250011882A1 (en) 2025-01-09
WO2023089186A1 (en) 2023-05-25
EP4437142A1 (en) 2024-10-02
CN118339315A (zh) 2024-07-12

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