JP2024539193A5 - - Google Patents
Info
- Publication number
- JP2024539193A5 JP2024539193A5 JP2024523783A JP2024523783A JP2024539193A5 JP 2024539193 A5 JP2024539193 A5 JP 2024539193A5 JP 2024523783 A JP2024523783 A JP 2024523783A JP 2024523783 A JP2024523783 A JP 2024523783A JP 2024539193 A5 JP2024539193 A5 JP 2024539193A5
- Authority
- JP
- Japan
- Prior art keywords
- rnai agent
- nucleotide
- agent according
- modified
- nucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163270849P | 2021-10-22 | 2021-10-22 | |
| US63/270,849 | 2021-10-22 | ||
| US202263308289P | 2022-02-09 | 2022-02-09 | |
| US63/308,289 | 2022-02-09 | ||
| US202263345654P | 2022-05-25 | 2022-05-25 | |
| US63/345,654 | 2022-05-25 | ||
| PCT/US2022/078498 WO2023070082A2 (en) | 2021-10-22 | 2022-10-21 | Rnai agents for inhibiting expression of matrix metalloproteinase 7(mmp7), compositions thereof, and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024539193A JP2024539193A (ja) | 2024-10-28 |
| JP2024539193A5 true JP2024539193A5 (cg-RX-API-DMAC7.html) | 2025-10-28 |
Family
ID=86059695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523783A Pending JP2024539193A (ja) | 2021-10-22 | 2022-10-21 | マトリックスメタロプロテイナーゼ７（ＭＭＰ７）の発現を抑制するためのＲＮＡｉ剤、その組成物、及び使用の方法 |
Country Status (13)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202503060A (zh) * | 2023-06-13 | 2025-01-16 | 大陸商上海拓界生物醫藥科技有限公司 | 靶向ＭＭＰ７的ｓｉＲＮＡ、ｓｉＲＮＡ綴合物及其醫藥用途 |
| CN121693569A (zh) | 2023-07-28 | 2026-03-17 | 长春金赛药业有限责任公司 | siRNA及其组合物 |
| CN120309596A (zh) * | 2024-01-15 | 2025-07-15 | 武汉人福创新药物研发中心有限公司 | 靶向αvβ6的化合物及其用途 |
| WO2025228156A1 (zh) * | 2024-04-30 | 2025-11-06 | 北京炫景瑞医药科技有限公司 | 肾靶向的双链寡核苷酸缀合物及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030194704A1 (en) * | 2002-04-03 | 2003-10-16 | Penn Sharron Gaynor | Human genome-derived single exon nucleic acid probes useful for gene expression analysis two |
| US20050118625A1 (en) * | 2003-10-02 | 2005-06-02 | Mounts William M. | Nucleic acid arrays for detecting gene expression associated with human osteoarthritis and human proteases |
| WO2006092795A2 (en) * | 2005-03-01 | 2006-09-08 | Qbi Enterprises Ltd. | Oligoribonucleotides and methods of use thereof for treatment of ocular scarring and other fibrotic conditions |
| WO2019089765A1 (en) * | 2017-11-01 | 2019-05-09 | Arrowhead Pharmcaceuticals, Inc. | Integrin ligands and uses thereof |
| US12372530B2 (en) * | 2017-11-15 | 2025-07-29 | Beth Israel Deaconess Medical Center, Inc. | Markers for the diagnosis and treatment of non-alcoholic steatohepatitis (NASH) and advanced liver fibrosis |
| CN116783294A (zh) * | 2020-09-11 | 2023-09-19 | 箭头药业股份有限公司 | 整联蛋白靶向配体及其用途 |
-
2022
- 2022-10-21 US US18/048,577 patent/US20230265437A1/en active Pending
- 2022-10-21 CA CA3235224A patent/CA3235224A1/en active Pending
- 2022-10-21 IL IL312239A patent/IL312239A/en unknown
- 2022-10-21 WO PCT/US2022/078498 patent/WO2023070082A2/en not_active Ceased
- 2022-10-21 KR KR1020247016352A patent/KR20240099296A/ko active Pending
- 2022-10-21 EP EP22884722.4A patent/EP4419689A2/en active Pending
- 2022-10-21 AU AU2022368927A patent/AU2022368927A1/en active Pending
- 2022-10-21 MX MX2024004912A patent/MX2024004912A/es unknown
- 2022-10-21 TW TW111140110A patent/TW202334416A/zh unknown
- 2022-10-21 JP JP2024523783A patent/JP2024539193A/ja active Pending
- 2022-10-21 PE PE2024000898A patent/PE20241185A1/es unknown
-
2024
- 2024-04-15 CL CL2024001175A patent/CL2024001175A1/es unknown
- 2024-04-23 CO CONC2024/0005110A patent/CO2024005110A2/es unknown