JP2024538477A5 - - Google Patents

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Publication number
JP2024538477A5
JP2024538477A5 JP2023580572A JP2023580572A JP2024538477A5 JP 2024538477 A5 JP2024538477 A5 JP 2024538477A5 JP 2023580572 A JP2023580572 A JP 2023580572A JP 2023580572 A JP2023580572 A JP 2023580572A JP 2024538477 A5 JP2024538477 A5 JP 2024538477A5
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JP
Japan
Prior art keywords
specific
amino acid
amino acids
benign
pathogenicity
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2023580572A
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English (en)
Japanese (ja)
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JP2024538477A (ja
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Publication date
Priority claimed from US17/533,091 external-priority patent/US11538555B1/en
Application filed filed Critical
Priority claimed from PCT/US2022/045825 external-priority patent/WO2023059752A1/en
Publication of JP2024538477A publication Critical patent/JP2024538477A/ja
Publication of JP2024538477A5 publication Critical patent/JP2024538477A5/ja
Pending legal-status Critical Current

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JP2023580572A 2021-10-06 2022-10-05 タンパク質構造に基づくタンパク質言語モデル Pending JP2024538477A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202163253122P 2021-10-06 2021-10-06
US63/253,122 2021-10-06
US202163281579P 2021-11-19 2021-11-19
US202163281592P 2021-11-19 2021-11-19
US63/281,579 2021-11-19
US63/281,592 2021-11-19
US17/533,091 US11538555B1 (en) 2021-10-06 2021-11-22 Protein structure-based protein language models
US17/533,091 2021-11-22
US17/953,293 2022-09-26
US17/953,293 US20230108368A1 (en) 2021-10-06 2022-09-26 Combined and transfer learning of a variant pathogenicity predictor using gapped and non-gapped protein samples
US17/953,286 2022-09-26
US17/953,286 US20230108241A1 (en) 2021-10-06 2022-09-26 Predicting variant pathogenicity from evolutionary conservation using three-dimensional (3d) protein structure voxels
PCT/US2022/045825 WO2023059752A1 (en) 2021-10-06 2022-10-05 Protein structure-based protein language models

Publications (2)

Publication Number Publication Date
JP2024538477A JP2024538477A (ja) 2024-10-23
JP2024538477A5 true JP2024538477A5 (https=) 2025-10-17

Family

ID=89808344

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023580573A Pending JP2024538478A (ja) 2021-10-06 2022-10-05 ギャップ付き及び非ギャップタンパク質サンプルを使用した変異体病原性予測器の複合学習及び転移学習
JP2023580572A Pending JP2024538477A (ja) 2021-10-06 2022-10-05 タンパク質構造に基づくタンパク質言語モデル
JP2023579826A Pending JP2024538475A (ja) 2021-10-06 2022-10-05 三次元(3d)タンパク質構造ボクセルを用いた進化的保存からの変異体病原性の予測

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023580573A Pending JP2024538478A (ja) 2021-10-06 2022-10-05 ギャップ付き及び非ギャップタンパク質サンプルを使用した変異体病原性予測器の複合学習及び転移学習

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023579826A Pending JP2024538475A (ja) 2021-10-06 2022-10-05 三次元(3d)タンパク質構造ボクセルを用いた進化的保存からの変異体病原性の予測

Country Status (4)

Country Link
EP (3) EP4413577A1 (https=)
JP (3) JP2024538478A (https=)
KR (3) KR20240088641A (https=)
CN (2) CN117546242A (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117178327A (zh) * 2021-04-15 2023-12-05 因美纳有限公司 使用深度卷积神经网络来预测变体致病性的多通道蛋白质体素化
CN118629516B (zh) * 2024-05-17 2025-09-16 安徽农业大学 一种基于多模态特征和孪生网络的神经肽预测方法及系统
CN119560009B (zh) * 2025-01-22 2025-06-24 浙江工业大学 一种蛋白质翻译后修饰与疾病关联预测系统及方法

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