JP2024535868A5 - - Google Patents
Info
- Publication number
- JP2024535868A5 JP2024535868A5 JP2024517052A JP2024517052A JP2024535868A5 JP 2024535868 A5 JP2024535868 A5 JP 2024535868A5 JP 2024517052 A JP2024517052 A JP 2024517052A JP 2024517052 A JP2024517052 A JP 2024517052A JP 2024535868 A5 JP2024535868 A5 JP 2024535868A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- nucleic acid
- recombinant nucleic
- acid molecule
- recombinant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163245661P | 2021-09-17 | 2021-09-17 | |
| US63/245,661 | 2021-09-17 | ||
| PCT/US2022/076618 WO2023044461A2 (en) | 2021-09-17 | 2022-09-16 | Switch receptors using il-9 signaling domains |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024535868A JP2024535868A (ja) | 2024-10-02 |
| JP2024535868A5 true JP2024535868A5 (https=) | 2025-09-25 |
Family
ID=83688655
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024517113A Pending JP2024535872A (ja) | 2021-09-17 | 2022-09-16 | Ｉｌ－９シグナル伝達ドメインを使用したスイッチ受容体 |
| JP2024517052A Pending JP2024535868A (ja) | 2021-09-17 | 2022-09-16 | Ｉｌ－９シグナル伝達ドメインを使用したスイッチ受容体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024517113A Pending JP2024535872A (ja) | 2021-09-17 | 2022-09-16 | Ｉｌ－９シグナル伝達ドメインを使用したスイッチ受容体 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US12202884B2 (https=) |
| EP (2) | EP4402162A2 (https=) |
| JP (2) | JP2024535872A (https=) |
| CN (2) | CN118251410A (https=) |
| AU (2) | AU2022348588A1 (https=) |
| CA (2) | CA3232668A1 (https=) |
| WO (2) | WO2023044457A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022202287A1 (en) | 2021-04-07 | 2022-10-27 | Wisconsin Alumni Research Foundation | Liquid Crystal-Infused Slippery Anti-Fouling Surfaces |
| AU2022348588A1 (en) | 2021-09-17 | 2024-04-04 | Parker Institute For Cancer Immunotherapy | Switch receptors using il-9 signaling domains |
| EP4402160A4 (en) * | 2021-09-17 | 2025-11-19 | Univ Pennsylvania | CHIMERIC ANTIGENIC RECEPTORS COMPRISING AN INTERLEUKIN-9 RECEPTOR SIGNALING DOMAIN |
| WO2024019984A1 (en) * | 2022-07-18 | 2024-01-25 | Cargo Therapeutics, Inc. | Cytokine receptor switch polypeptides and uses thereof |
| WO2025039159A1 (en) * | 2023-08-21 | 2025-02-27 | Hangzhou Hervor Therapeutics Co., Ltd | Synthetic cytokine signaling system, preparation method, and uses thereof |
| WO2025117789A1 (en) * | 2023-12-01 | 2025-06-05 | Parker Institute For Cancer Immunotherapy | Engineered immune signaling constructs |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| WO2010006111A2 (en) | 2008-07-10 | 2010-01-14 | Merck & Co., Inc. | Methods of using compositions comprising mir-192 and/or mir-215 for the treatment of cancer |
| WO2016127257A1 (en) | 2015-02-12 | 2016-08-18 | University Health Network | Chimeric antigen receptors |
| PT3328894T (pt) | 2015-08-06 | 2019-02-13 | Agency Science Tech & Res | Anticorpos de cadeia comum gama/il2rbeta |
| GB201514875D0 (en) * | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| CN117659160A (zh) | 2015-09-11 | 2024-03-08 | 小利兰·斯坦福大学托管委员会 | 生物相关正交细胞因子/受体对 |
| EP3827838B1 (en) | 2015-12-16 | 2023-06-07 | The Walter and Eliza Hall Institute of Medical Research | Inhibition of cytokine-induced sh2 protein in nk cells |
| AU2019215031C1 (en) | 2018-01-31 | 2026-02-26 | Novartis Ag | Combination therapy using a chimeric antigen receptor |
| CN111819192A (zh) | 2018-03-02 | 2020-10-23 | 艾洛基治疗公司 | 可诱导的嵌合细胞激素受体 |
| CN110615843B (zh) | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种包含第三信号受体的嵌合抗原受体及其应用 |
| JP2020110135A (ja) | 2019-01-09 | 2020-07-27 | エーテーハー チューリッヒＥｔｈ Ｚｕｒｉｃｈ | 汎用細胞外分子センサー |
| WO2020163634A1 (en) | 2019-02-08 | 2020-08-13 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Chimeric cytokine receptors |
| GB201911187D0 (en) * | 2019-08-05 | 2019-09-18 | Autolus Ltd | Receptor |
| WO2021050752A1 (en) | 2019-09-11 | 2021-03-18 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric orthogonal receptor proteins and methods of use |
| WO2021141986A1 (en) | 2020-01-07 | 2021-07-15 | St. Jude Children's Research Hospital, Inc. | Chimeric gmcsf-il18 receptor |
| CN115427440A (zh) | 2020-02-25 | 2022-12-02 | 圭尔医疗有限公司 | 用于工程化细胞的嵌合受体 |
| CA3179414A1 (en) | 2020-04-06 | 2021-10-14 | Synthekine, Inc. | Human immune cells genomically modified to express orthogonal receptors |
| WO2022192346A1 (en) | 2021-03-09 | 2022-09-15 | The Trustees Of The University Of Pennsylvania | Selective stimulation of t cells in solid tumors using oncolytic viral delivery of orthogonal il-2 |
| EP4402160A4 (en) | 2021-09-17 | 2025-11-19 | Univ Pennsylvania | CHIMERIC ANTIGENIC RECEPTORS COMPRISING AN INTERLEUKIN-9 RECEPTOR SIGNALING DOMAIN |
| AU2022348588A1 (en) | 2021-09-17 | 2024-04-04 | Parker Institute For Cancer Immunotherapy | Switch receptors using il-9 signaling domains |
| EP4554972A1 (en) | 2022-07-11 | 2025-05-21 | The Board of Trustees of the Leland Stanford Junior University | Tunable cytokine receptor signaling domains |
-
2022
- 2022-09-16 AU AU2022348588A patent/AU2022348588A1/en active Pending
- 2022-09-16 AU AU2022347445A patent/AU2022347445A1/en active Pending
- 2022-09-16 CA CA3232668A patent/CA3232668A1/en active Pending
- 2022-09-16 EP EP22786723.1A patent/EP4402162A2/en active Pending
- 2022-09-16 CN CN202280074481.3A patent/CN118251410A/zh active Pending
- 2022-09-16 CA CA3232664A patent/CA3232664A1/en active Pending
- 2022-09-16 US US17/946,916 patent/US12202884B2/en active Active
- 2022-09-16 CN CN202280074174.5A patent/CN118234746A/zh active Pending
- 2022-09-16 WO PCT/US2022/076612 patent/WO2023044457A1/en not_active Ceased
- 2022-09-16 JP JP2024517113A patent/JP2024535872A/ja active Pending
- 2022-09-16 EP EP22786722.3A patent/EP4402161A1/en active Pending
- 2022-09-16 JP JP2024517052A patent/JP2024535868A/ja active Pending
- 2022-09-16 WO PCT/US2022/076618 patent/WO2023044461A2/en not_active Ceased
- 2022-09-16 US US17/946,894 patent/US20230110313A1/en not_active Abandoned
-
2023
- 2023-06-02 US US18/328,473 patent/US12221469B2/en active Active
-
2024
- 2024-12-09 US US18/974,281 patent/US20250179148A1/en active Pending
- 2024-12-27 US US19/003,599 patent/US20250136664A1/en active Pending
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