JP2024534231A - Ck2媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 - Google Patents

Ck2媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 Download PDF

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JP2024534231A
JP2024534231A JP2024514574A JP2024514574A JP2024534231A JP 2024534231 A JP2024534231 A JP 2024534231A JP 2024514574 A JP2024514574 A JP 2024514574A JP 2024514574 A JP2024514574 A JP 2024514574A JP 2024534231 A JP2024534231 A JP 2024534231A
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seq
peptide
polypeptides
polypeptide
identified
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JP2024514574A
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JP2024534231A5 (https=
Inventor
ゴンザレス、ヨルダンカ マスフォロール
ペレス、ヒルダ、エリサ ガライ
アコスタ、オズワルド レジェス
ネグリン、ヤセル ペレラ
メネンデス、エヴェリン カバレロ
レぺス、ルイス、ハビエル ゴンザレス
ペレス、ウラジミール、アルマンド ベサーダ
ロドリゲス、シルビオ、エルネスト ペレア
ニエト、ジェラルド、エンリケ ギレン
ブランコ、ソニア ゴンザレス
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Centro de Ingenieria Genetica y Biotecnologia CIGB
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Centro de Ingenieria Genetica y Biotecnologia CIGB
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Publication of JP2024534231A publication Critical patent/JP2024534231A/ja
Publication of JP2024534231A5 publication Critical patent/JP2024534231A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11001Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
JP2024514574A 2021-07-09 2022-07-07 Ck2媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物 Pending JP2024534231A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU2021000058A CU24766B1 (es) 2021-07-09 2021-07-09 Péptidos lineales que inhiben la fosforilación mediada por ck2
CU2021-0058 2021-07-09
PCT/CU2022/050007 WO2023280330A1 (es) 2021-07-09 2022-07-07 Péptidos lineales que inhiben la fosforilación mediada por ck2 y composiciones que los comprenden

Publications (2)

Publication Number Publication Date
JP2024534231A true JP2024534231A (ja) 2024-09-18
JP2024534231A5 JP2024534231A5 (https=) 2025-05-23

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ID=83080989

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JP2024514574A Pending JP2024534231A (ja) 2021-07-09 2022-07-07 Ck2媒介リン酸化を阻害する線状ペプチド及びそれを含む組成物

Country Status (11)

Country Link
US (1) US20240317827A1 (https=)
EP (1) EP4368710A1 (https=)
JP (1) JP2024534231A (https=)
KR (1) KR20240032882A (https=)
CN (1) CN117795064A (https=)
AR (1) AR126388A1 (https=)
AU (1) AU2022308094A1 (https=)
CA (1) CA3225387A1 (https=)
CU (1) CU24766B1 (https=)
MX (1) MX2024000542A (https=)
WO (1) WO2023280330A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118290537B (zh) * 2024-05-09 2025-02-07 永州中古生物技术有限公司 一种在nci-h460细胞系中对ck2起到抑制作用的多肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23225A1 (es) 2001-12-20 2007-08-30 Ct Ingenieria Genetica Biotech PéPTIDOS PARA EL TRATAMIENTO DEL CáNCER ASOCIADO AL VIRUS PAPILOMA HUMANO (VPH) Y DE OTROS TUMORES EPITELIALES
WO2006020207A2 (en) * 2004-07-19 2006-02-23 University Of Cincinnati Compounds for control of appetite
CA2629751A1 (en) * 2004-11-12 2006-05-18 The University Of British Columbia Antimicrobial peptides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCI REP., vol. 9(1):11018, JPN6026014959, 2019, ISSN: 0005841827 *

Also Published As

Publication number Publication date
CU24766B1 (es) 2025-08-13
WO2023280330A1 (es) 2023-01-12
CU20210058A7 (es) 2023-02-13
US20240317827A1 (en) 2024-09-26
KR20240032882A (ko) 2024-03-12
AU2022308094A1 (en) 2024-02-01
MX2024000542A (es) 2024-02-02
EP4368710A1 (en) 2024-05-15
AR126388A1 (es) 2023-10-11
CN117795064A (zh) 2024-03-29
CA3225387A1 (en) 2023-01-12

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