JP2024532619A5 - - Google Patents

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Publication number
JP2024532619A5
JP2024532619A5 JP2024537306A JP2024537306A JP2024532619A5 JP 2024532619 A5 JP2024532619 A5 JP 2024532619A5 JP 2024537306 A JP2024537306 A JP 2024537306A JP 2024537306 A JP2024537306 A JP 2024537306A JP 2024532619 A5 JP2024532619 A5 JP 2024532619A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
receptor antibody
acid sequence
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024537306A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024532619A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/075545 external-priority patent/WO2023028606A1/en
Publication of JP2024532619A publication Critical patent/JP2024532619A/ja
Publication of JP2024532619A5 publication Critical patent/JP2024532619A5/ja
Pending legal-status Critical Current

Links

JP2024537306A 2021-08-27 2022-08-26 併用療法 Pending JP2024532619A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163238068P 2021-08-27 2021-08-27
US63/238,068 2021-08-27
US202263301012P 2022-01-19 2022-01-19
US63/301,012 2022-01-19
US202263333351P 2022-04-21 2022-04-21
US63/333,351 2022-04-21
PCT/US2022/075545 WO2023028606A1 (en) 2021-08-27 2022-08-26 Combination therapies

Publications (2)

Publication Number Publication Date
JP2024532619A JP2024532619A (ja) 2024-09-05
JP2024532619A5 true JP2024532619A5 (https=) 2025-09-01

Family

ID=83897998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537306A Pending JP2024532619A (ja) 2021-08-27 2022-08-26 併用療法

Country Status (10)

Country Link
US (1) US20240325530A1 (https=)
EP (1) EP4392137A1 (https=)
JP (1) JP2024532619A (https=)
KR (1) KR20240099142A (https=)
AU (1) AU2022332306A1 (https=)
CA (1) CA3229355A1 (https=)
IL (1) IL310919A (https=)
MX (1) MX2024002467A (https=)
TW (1) TW202323296A (https=)
WO (1) WO2023028606A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021189019A1 (en) 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Activin receptor type ii chimeras and methods of use thereof
WO2021189010A1 (en) 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Methods of using activin receptor type iib variants
PT4408840T (pt) 2021-09-27 2025-10-07 Terns Pharmaceuticals Inc Ácidos benzimidazolocarboxílicos como agonistas de glp-1r
CN118401519A (zh) 2021-10-25 2024-07-26 拓臻制药公司 作为glp-1r激动剂的化合物
TW202339798A (zh) * 2022-01-19 2023-10-16 美商維紗妮絲生物公司 Actrii抗體之治療
CN119095843A (zh) 2022-02-23 2024-12-06 拓臻制药公司 作为glp-1r激动剂的化合物
JP2025529933A (ja) 2022-08-26 2025-09-09 バーサニス・バイオ・インコーポレイテッド ActRII抗体固定単位用量の治療
EP4568664B1 (en) 2023-04-07 2026-04-01 Terns Pharmaceuticals, Inc. Combination comprising a thr-beta agonist and a glp-1r agonist for use in treating obesity
WO2025027052A1 (en) 2023-07-31 2025-02-06 Sixpeaks Bio Ag Antibody conjugates and fusion proteins
WO2025106773A1 (en) * 2023-11-17 2025-05-22 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea with a combination of a glp-1 agonist and a second active agent
TW202535467A (zh) * 2023-12-29 2025-09-16 大陸商江蘇恆瑞醫藥股份有限公司 抗體-多肽偶聯物及其醫藥用途
WO2025147483A1 (en) * 2024-01-02 2025-07-10 Keros Therapeutics, Inc. Methods of using activin receptor type ii chimeras
WO2025183966A1 (en) 2024-02-28 2025-09-04 Versanis Bio, Inc. Actrii antibodies with extended half life
WO2025217521A1 (en) * 2024-04-12 2025-10-16 Jnana Therapeutics Inc. Treating chronic kidney disease with a combination of a slc6a19 inhibitor and a glp-1 agonist
WO2025247309A1 (zh) * 2024-05-31 2025-12-04 上海齐鲁制药研究中心有限公司 融合蛋白分子及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20120532A1 (es) 2009-04-27 2012-05-18 Novartis Ag ANTICUERPOS ANTI-ActRIIB
JOP20190152A1 (ar) 2016-12-21 2019-06-20 Novartis Ag مضادات الميوستاتين، الآكتيفين أو مستقبلات الآكتيفين للاستخدام في علاج السمنة والحالات ذات الصلة
PT3565592T (pt) * 2017-01-06 2023-05-31 Scholar Rock Inc Tratamento de doenças metabólicas através da inibição da ativação da miostatina

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