JP2024530926A - 低アレルゲン性ピーナッツアレルゲン、その製造方法、及びその使用 - Google Patents
低アレルゲン性ピーナッツアレルゲン、その製造方法、及びその使用 Download PDFInfo
- Publication number
- JP2024530926A JP2024530926A JP2024506789A JP2024506789A JP2024530926A JP 2024530926 A JP2024530926 A JP 2024530926A JP 2024506789 A JP2024506789 A JP 2024506789A JP 2024506789 A JP2024506789 A JP 2024506789A JP 2024530926 A JP2024530926 A JP 2024530926A
- Authority
- JP
- Japan
- Prior art keywords
- seq
- recombinant
- arahl
- mutant polypeptide
- ara
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163228604P | 2021-08-03 | 2021-08-03 | |
| US202163228606P | 2021-08-03 | 2021-08-03 | |
| US63/228,604 | 2021-08-03 | ||
| US63/228,606 | 2021-08-03 | ||
| US202163284108P | 2021-11-30 | 2021-11-30 | |
| US63/284,108 | 2021-11-30 | ||
| US202163292441P | 2021-12-22 | 2021-12-22 | |
| US63/292,441 | 2021-12-22 | ||
| US202263311117P | 2022-02-17 | 2022-02-17 | |
| US63/311,117 | 2022-02-17 | ||
| US202263319393P | 2022-03-14 | 2022-03-14 | |
| US202263319394P | 2022-03-14 | 2022-03-14 | |
| US63/319,393 | 2022-03-14 | ||
| US63/319,394 | 2022-03-14 | ||
| PCT/IB2022/057144 WO2023012652A2 (en) | 2021-08-03 | 2022-08-02 | Hypoallergenic peanut allergens, production and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024530926A true JP2024530926A (ja) | 2024-08-27 |
| JP2024530926A5 JP2024530926A5 (https=) | 2025-07-28 |
Family
ID=85155450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024506789A Pending JP2024530926A (ja) | 2021-08-03 | 2022-08-02 | 低アレルゲン性ピーナッツアレルゲン、その製造方法、及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20240390485A1 (https=) |
| EP (1) | EP4380957A4 (https=) |
| JP (1) | JP2024530926A (https=) |
| AU (1) | AU2022323847A1 (https=) |
| CA (1) | CA3226900A1 (https=) |
| WO (1) | WO2023012652A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024224738A1 (en) * | 2023-02-23 | 2025-09-18 | The General Hospital Corporation, D/B/A Massachusetts General Hospital | Mutant ara h 2 and ara h 6 proteins and uses thereof |
| WO2024256749A1 (en) | 2023-06-12 | 2024-12-19 | Desentum Oy | Hypoallergenic variants of major peanut allergen, ara h 2 |
| WO2026080920A1 (en) | 2024-10-13 | 2026-04-16 | Ukko Inc. | Mrna vaccine for peanut allergy treatment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002306850A1 (en) * | 2001-03-16 | 2002-10-03 | Panacea Pharmaceuticals | Methods and reagents for decreasing clinical reaction to allergy |
| US8057800B2 (en) * | 2004-06-10 | 2011-11-15 | Circassia Limited | Immunointeractive molecules and uses thereof |
| EP2664624A1 (en) * | 2012-05-15 | 2013-11-20 | Biomay Ag | Allergen variants |
| US20200124615A1 (en) * | 2016-12-29 | 2020-04-23 | Ukko Inc. | Methods for identifying and de-epitoping allergenic polypeptides |
| EP3793595A1 (en) * | 2018-05-15 | 2021-03-24 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising allergens |
-
2022
- 2022-08-02 JP JP2024506789A patent/JP2024530926A/ja active Pending
- 2022-08-02 WO PCT/IB2022/057144 patent/WO2023012652A2/en not_active Ceased
- 2022-08-02 CA CA3226900A patent/CA3226900A1/en active Pending
- 2022-08-02 EP EP22852444.3A patent/EP4380957A4/en active Pending
- 2022-08-02 US US18/292,959 patent/US20240390485A1/en active Pending
- 2022-08-02 AU AU2022323847A patent/AU2022323847A1/en active Pending
-
2023
- 2023-11-29 US US18/522,706 patent/US20240117020A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022323847A1 (en) | 2024-02-15 |
| WO2023012652A2 (en) | 2023-02-09 |
| EP4380957A4 (en) | 2025-09-03 |
| CA3226900A1 (en) | 2023-02-09 |
| US20240117020A1 (en) | 2024-04-11 |
| WO2023012652A3 (en) | 2023-04-06 |
| US20240390485A1 (en) | 2024-11-28 |
| EP4380957A2 (en) | 2024-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250717 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250717 |