JP2024528503A5 - - Google Patents

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Publication number
JP2024528503A5
JP2024528503A5 JP2023579696A JP2023579696A JP2024528503A5 JP 2024528503 A5 JP2024528503 A5 JP 2024528503A5 JP 2023579696 A JP2023579696 A JP 2023579696A JP 2023579696 A JP2023579696 A JP 2023579696A JP 2024528503 A5 JP2024528503 A5 JP 2024528503A5
Authority
JP
Japan
Prior art keywords
nucleotides
dsrna agent
chain
nucleotide
agent according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023579696A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024528503A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/035561 external-priority patent/WO2023278607A1/en
Publication of JP2024528503A publication Critical patent/JP2024528503A/ja
Publication of JP2024528503A5 publication Critical patent/JP2024528503A5/ja
Pending legal-status Critical Current

Links

JP2023579696A 2021-06-29 2022-06-29 ロイシンリッチリピートキナーゼ2(LRRK2)iRNA剤組成物およびその使用方法 Pending JP2024528503A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163216119P 2021-06-29 2021-06-29
US63/216,119 2021-06-29
US202263353953P 2022-06-21 2022-06-21
US63/353,953 2022-06-21
PCT/US2022/035561 WO2023278607A1 (en) 2021-06-29 2022-06-29 Leucine-rich repeat kinase 2 (lrrk2) irna agent compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024528503A JP2024528503A (ja) 2024-07-30
JP2024528503A5 true JP2024528503A5 (enExample) 2025-07-07

Family

ID=84692073

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023579696A Pending JP2024528503A (ja) 2021-06-29 2022-06-29 ロイシンリッチリピートキナーゼ2(LRRK2)iRNA剤組成物およびその使用方法

Country Status (13)

Country Link
US (1) US20240301426A1 (enExample)
EP (1) EP4363588A1 (enExample)
JP (1) JP2024528503A (enExample)
KR (1) KR20240033237A (enExample)
AU (1) AU2022303358A1 (enExample)
BR (1) BR112023027446A2 (enExample)
CA (1) CA3225740A1 (enExample)
CL (3) CL2023003984A1 (enExample)
CO (1) CO2023018579A2 (enExample)
IL (1) IL309548A (enExample)
MX (1) MX2024000065A (enExample)
TW (1) TW202317149A (enExample)
WO (1) WO2023278607A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4709855A2 (en) * 2023-05-12 2026-03-18 Alnylam Pharmaceuticals, Inc. Single-stranded loop oligonucleotides
EP4731763A1 (en) * 2023-06-20 2026-04-29 Adarx Pharmaceuticals, Inc. Lrrk2-modulating compositions and methods of use thereof
AU2024353921A1 (en) 2023-09-27 2026-04-16 Neuro3 Therapeutics (Suzhou) Ltd. Novel sirna constructs, therapeutics, and modifications
CN120082552A (zh) * 2023-12-01 2025-06-03 艾码生物科技(南京)有限公司 初级-miRNA及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9840703B2 (en) * 2013-01-11 2017-12-12 Children's Medical Center Corporation Methods and compositions for the production of siRNAs
TWI833770B (zh) * 2018-06-27 2024-03-01 美商Ionis製藥公司 用於減少 lrrk2 表現之化合物及方法

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