JP2024528503A5 - - Google Patents
Info
- Publication number
- JP2024528503A5 JP2024528503A5 JP2023579696A JP2023579696A JP2024528503A5 JP 2024528503 A5 JP2024528503 A5 JP 2024528503A5 JP 2023579696 A JP2023579696 A JP 2023579696A JP 2023579696 A JP2023579696 A JP 2023579696A JP 2024528503 A5 JP2024528503 A5 JP 2024528503A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotides
- dsrna agent
- chain
- nucleotide
- agent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163216119P | 2021-06-29 | 2021-06-29 | |
| US63/216,119 | 2021-06-29 | ||
| US202263353953P | 2022-06-21 | 2022-06-21 | |
| US63/353,953 | 2022-06-21 | ||
| PCT/US2022/035561 WO2023278607A1 (en) | 2021-06-29 | 2022-06-29 | Leucine-rich repeat kinase 2 (lrrk2) irna agent compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024528503A JP2024528503A (ja) | 2024-07-30 |
| JP2024528503A5 true JP2024528503A5 (cg-RX-API-DMAC10.html) | 2025-07-07 |
Family
ID=84692073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023579696A Pending JP2024528503A (ja) | 2021-06-29 | 2022-06-29 | ロイシンリッチリピートキナーゼ２（ＬＲＲＫ２）ｉＲＮＡ剤組成物およびその使用方法 |
Country Status (13)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024238385A2 (en) * | 2023-05-12 | 2024-11-21 | Alnylam Pharmaceuticals, Inc. | Single-stranded loop oligonucleotides |
| CN121712891A (zh) * | 2023-06-20 | 2026-03-20 | 阿达尔克斯制药有限公司 | Lrrk2调节组合物及其使用方法 |
| CN122074089A (zh) | 2023-09-27 | 2026-05-22 | 三晟医药公司 | 新型siRNA构建体、治疗剂和修饰 |
| CN120082552A (zh) * | 2023-12-01 | 2025-06-03 | 艾码生物科技(南京)有限公司 | 初级-miRNA及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007124096A2 (en) * | 2006-04-21 | 2007-11-01 | The Trustees Of Columbia University In The City Of New York | Lrrk2 regulaton of neuronal process morphology |
| GB201105137D0 (en) * | 2011-03-28 | 2011-05-11 | Isis Innovation | Therapeutic molecules for use in the suppression of Parkinson's disease |
| WO2014110205A1 (en) * | 2013-01-11 | 2014-07-17 | Children's Medical Center Corporation | Methods and compositions for the production of sirnas |
| EP3400300A4 (en) * | 2016-01-05 | 2019-08-07 | Ionis Pharmaceuticals, Inc. | PROCESS FOR REDUCING LRRK2 EXPRESSION |
| CA3098623A1 (en) * | 2018-05-07 | 2019-11-14 | Alnylam Pharmaceuticals, Inc. | Extrahepatic delivery |
| TWI833770B (zh) * | 2018-06-27 | 2024-03-01 | 美商Ionis製藥公司 | 用於減少 lrrk2 表現之化合物及方法 |
| EP3769768A1 (en) * | 2019-07-23 | 2021-01-27 | Consejo Superior de Investigaciones Cientificas (CSIC) | Compounds useful for the treatment of parkinson s disease |
-
2022
- 2022-06-29 KR KR1020247003234A patent/KR20240033237A/ko active Pending
- 2022-06-29 JP JP2023579696A patent/JP2024528503A/ja active Pending
- 2022-06-29 IL IL309548A patent/IL309548A/en unknown
- 2022-06-29 BR BR112023027446A patent/BR112023027446A2/pt unknown
- 2022-06-29 EP EP22834164.0A patent/EP4363588A4/en active Pending
- 2022-06-29 US US18/575,157 patent/US20240301426A1/en active Pending
- 2022-06-29 CA CA3225740A patent/CA3225740A1/en active Pending
- 2022-06-29 AU AU2022303358A patent/AU2022303358A1/en active Pending
- 2022-06-29 WO PCT/US2022/035561 patent/WO2023278607A1/en not_active Ceased
- 2022-06-29 TW TW111124391A patent/TW202317149A/zh unknown
- 2022-06-29 MX MX2024000065A patent/MX2024000065A/es unknown
-
2023
- 2023-12-28 CO CONC2023/0018579A patent/CO2023018579A2/es unknown
- 2023-12-29 CL CL2023003984A patent/CL2023003984A1/es unknown
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2025
- 2025-01-20 CL CL2025000168A patent/CL2025000168A1/es unknown
- 2025-10-28 CL CL2025003326A patent/CL2025003326A1/es unknown