JP2024527313A5 - - Google Patents
Info
- Publication number
- JP2024527313A5 JP2024527313A5 JP2023580435A JP2023580435A JP2024527313A5 JP 2024527313 A5 JP2024527313 A5 JP 2024527313A5 JP 2023580435 A JP2023580435 A JP 2023580435A JP 2023580435 A JP2023580435 A JP 2023580435A JP 2024527313 A5 JP2024527313 A5 JP 2024527313A5
- Authority
- JP
- Japan
- Prior art keywords
- raav
- vector
- sequence
- pharmaceutical composition
- capsid protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163215833P | 2021-06-28 | 2021-06-28 | |
| US63/215,833 | 2021-06-28 | ||
| US202263267440P | 2022-02-02 | 2022-02-02 | |
| US63/267,440 | 2022-02-02 | ||
| US202263342240P | 2022-05-16 | 2022-05-16 | |
| US63/342,240 | 2022-05-16 | ||
| PCT/US2022/035091 WO2023278305A1 (en) | 2021-06-28 | 2022-06-27 | Methods and compositions for tau reduction gene therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024527313A JP2024527313A (ja) | 2024-07-24 |
| JP2024527313A5 true JP2024527313A5 (enExample) | 2025-06-25 |
Family
ID=82694082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023580435A Pending JP2024527313A (ja) | 2021-06-28 | 2022-06-27 | タウ低減遺伝子療法のための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240269161A1 (enExample) |
| EP (1) | EP4362986A1 (enExample) |
| JP (1) | JP2024527313A (enExample) |
| AU (1) | AU2022301044A1 (enExample) |
| CA (1) | CA3223506A1 (enExample) |
| WO (1) | WO2023278305A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12630842B2 (en) | 2020-05-13 | 2026-05-19 | Voyager Therapeutics, Inc. | Redirection of tropism of AAV capsids |
| EP4754256A1 (en) * | 2023-08-02 | 2026-06-10 | Consejo Nacional de Investigaciones Científicas Y Técnicas (CONICET) | Micrornas designed against the microtubule-associated protein tau for the treatment of tauopathies |
| WO2025122644A1 (en) * | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for regulating mapt |
| WO2025128817A1 (en) * | 2023-12-15 | 2025-06-19 | Genzyme Corporation | Artificial micrornas targeting tau |
| WO2025212467A1 (en) | 2024-03-31 | 2025-10-09 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of microtubule associated protein tau (mapt), compositions thereof, and methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004514407A (ja) | 2000-04-28 | 2004-05-20 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 異種キャプシド中にシュードタイピングされたａａｖ５キャプシドおよびａａｖ５ベクターを含む組換えａａｖベクター |
| DE10120265A1 (de) | 2001-04-25 | 2002-11-14 | Deutsches Krebsforsch | AAV-Helferplasmide zur Helfervirus-freien Verpackung und Pseudotypisierung von AAV-Vektoren |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| US9951330B2 (en) * | 2013-07-11 | 2018-04-24 | The Trustees Of Columbia University In The City Of New York | Micrornas that silence tau expression |
| MX2020004005A (es) * | 2017-10-03 | 2020-10-05 | Prevail Therapeutics Inc | Terapias genicas para los trastornos lisosomales. |
| BR112021020157A2 (pt) * | 2019-04-10 | 2021-12-14 | Prevail Therapeutics Inc | Terapias gênicas para transtornos lisossomais |
| WO2021092518A1 (en) * | 2019-11-08 | 2021-05-14 | The Board Of Regents Of The University Of Texas | Transgene cassettes, aav vectors and aav viral vectors for the expression of human codon-optimized slc6a1 |
-
2022
- 2022-06-27 US US18/569,019 patent/US20240269161A1/en active Pending
- 2022-06-27 EP EP22747202.4A patent/EP4362986A1/en active Pending
- 2022-06-27 AU AU2022301044A patent/AU2022301044A1/en active Pending
- 2022-06-27 WO PCT/US2022/035091 patent/WO2023278305A1/en not_active Ceased
- 2022-06-27 CA CA3223506A patent/CA3223506A1/en active Pending
- 2022-06-27 JP JP2023580435A patent/JP2024527313A/ja active Pending