JP2024526938A5 - - Google Patents

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Publication number
JP2024526938A5
JP2024526938A5 JP2024503838A JP2024503838A JP2024526938A5 JP 2024526938 A5 JP2024526938 A5 JP 2024526938A5 JP 2024503838 A JP2024503838 A JP 2024503838A JP 2024503838 A JP2024503838 A JP 2024503838A JP 2024526938 A5 JP2024526938 A5 JP 2024526938A5
Authority
JP
Japan
Prior art keywords
exogenous polypeptide
polypeptide
exogenous
split intein
dystrophin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024503838A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024526938A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/038032 external-priority patent/WO2023004125A2/en
Publication of JP2024526938A publication Critical patent/JP2024526938A/ja
Publication of JP2024526938A5 publication Critical patent/JP2024526938A5/ja
Pending legal-status Critical Current

Links

JP2024503838A 2021-07-23 2022-07-22 複数のベクターを共送達することによる、大きなタンパク質の産生方法 Pending JP2024526938A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163225212P 2021-07-23 2021-07-23
US63/225,212 2021-07-23
US202163256819P 2021-10-18 2021-10-18
US63/256,819 2021-10-18
PCT/US2022/038032 WO2023004125A2 (en) 2021-07-23 2022-07-22 Generation of large proteins by co-delivery of multiple vectors

Publications (2)

Publication Number Publication Date
JP2024526938A JP2024526938A (ja) 2024-07-19
JP2024526938A5 true JP2024526938A5 (cg-RX-API-DMAC7.html) 2025-07-29

Family

ID=84978755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024503838A Pending JP2024526938A (ja) 2021-07-23 2022-07-22 複数のベクターを共送達することによる、大きなタンパク質の産生方法

Country Status (4)

Country Link
US (1) US20250099616A1 (cg-RX-API-DMAC7.html)
EP (1) EP4373949A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024526938A (cg-RX-API-DMAC7.html)
WO (1) WO2023004125A2 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025015036A1 (en) * 2023-07-10 2025-01-16 Kate Therapeutics, Inc. Aav gene therapy approach for treating lgmd2b/dysferlinopathy
WO2025017169A1 (en) 2023-07-20 2025-01-23 Genethon Novel mididystrophins
WO2025160497A1 (en) * 2024-01-26 2025-07-31 The Trustees Of Indiana University Aav delivery system for full-length dystrophin
WO2025217117A1 (en) * 2024-04-08 2025-10-16 The Trustees Of The University Of Pennsylvania Compositions with cardiac and skeletal muscle-specific targeting motifs and uses thereof
WO2026109723A1 (en) * 2024-11-22 2026-05-28 Katholieke Universiteit Leuven Efficient intein splicing in dual aav gene delivery

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544786B1 (en) * 1999-10-15 2003-04-08 University Of Pittsburgh Of The Commonwealth Of Higher Education Method and vector for producing and transferring trans-spliced peptides
JP6177780B2 (ja) * 2011-09-28 2017-08-09 エラ、ビオテック、ソシエダッド、アノニマＥｒａ Ｂｉｏｔｅｃｈ， Ｓ．Ａ． スプリットインテインおよびその使用
WO2018226602A1 (en) * 2017-06-05 2018-12-13 Research Institute At Nationwide Children's Hospital Enhanced modified viral capsid proteins
CA3116606A1 (en) * 2018-10-15 2020-04-23 Fondazione Telethon Intein proteins and uses thereof

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