JP2024526820A - Ａｃｔｒｉｉタンパク質およびその用途 - Google Patents

Ａｃｔｒｉｉタンパク質およびその用途 Download PDF

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Publication number
JP2024526820A
JP2024526820A JP2024502611A JP2024502611A JP2024526820A JP 2024526820 A JP2024526820 A JP 2024526820A JP 2024502611 A JP2024502611 A JP 2024502611A JP 2024502611 A JP2024502611 A JP 2024502611A JP 2024526820 A JP2024526820 A JP 2024526820A
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JP
Japan
Prior art keywords
patient
polypeptide
telangiectasia
actrii
actrii polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2024502611A
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English (en)
Japanese (ja)
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JP2024526820A5 (https=
JPWO2023003815A5 (https=
Inventor
デ・オリヴェイラ・ペーナ，ジャネーテ
Original Assignee
アクセルロン ファーマ インコーポレイテッド
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Application filed by アクセルロン ファーマ インコーポレイテッド filed Critical アクセルロン ファーマ インコーポレイテッド
Publication of JP2024526820A publication Critical patent/JP2024526820A/ja
Publication of JP2024526820A5 publication Critical patent/JP2024526820A5/ja
Publication of JPWO2023003815A5 publication Critical patent/JPWO2023003815A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP2024502611A 2021-07-19 2022-07-18 Ａｃｔｒｉｉタンパク質およびその用途 Pending JP2024526820A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163223265P 2021-07-19 2021-07-19
US63/223,265 2021-07-19
PCT/US2022/037479 WO2023003815A1 (en) 2021-07-19 2022-07-18 Actrii proteins and uses thereof

Publications (3)

Publication Number Publication Date
JP2024526820A true JP2024526820A (ja) 2024-07-19
JP2024526820A5 JP2024526820A5 (https=) 2025-07-17
JPWO2023003815A5 JPWO2023003815A5 (https=) 2025-07-17

Family

ID=84979535

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024502611A Pending JP2024526820A (ja) 2021-07-19 2022-07-18 Ａｃｔｒｉｉタンパク質およびその用途

Country Status (18)

Country Link
US (1) US20240327494A1 (https=)
EP (1) EP4373577A4 (https=)
JP (1) JP2024526820A (https=)
KR (1) KR20240049857A (https=)
CN (1) CN117957014A (https=)
AU (1) AU2022316103A1 (https=)
CA (1) CA3225613A1 (https=)
CL (1) CL2024000151A1 (https=)
CO (1) CO2024001551A2 (https=)
CR (1) CR20240061A (https=)
DO (1) DOP2024000016A (https=)
EC (1) ECSP24012819A (https=)
GE (1) GEAP202416461A (https=)
IL (1) IL310141A (https=)
JO (1) JOP20240010A1 (https=)
MX (1) MX2024000829A (https=)
PE (1) PE20240777A1 (https=)
WO (1) WO2023003815A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021189010A1 (en) 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Methods of using activin receptor type iib variants
IL296394A (en) 2020-03-20 2022-11-01 Keros Therapeutics Inc Type ii activin receptor chimeras and methods of using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180055822A1 (en) * 2015-03-13 2018-03-01 Repoceuticals Aps Melatonin for Preventing and Treating Radiation Cystitis
CA3005975A1 (en) * 2015-11-23 2017-06-01 Acceleron Pharma Inc. Methods for treating eye disorders
HRP20210694T1 (hr) * 2016-07-15 2021-09-17 Acceleron Pharma, Inc. Pripravci koji sadrže actriia polipeptide za uporabu za liječenje plućne hipertenzije

Also Published As

Publication number Publication date
CR20240061A (es) 2024-05-02
EP4373577A4 (en) 2025-05-14
CL2024000151A1 (es) 2024-08-09
CA3225613A1 (en) 2023-01-26
WO2023003815A9 (en) 2023-05-11
KR20240049857A (ko) 2024-04-17
PE20240777A1 (es) 2024-04-17
IL310141A (en) 2024-03-01
WO2023003815A1 (en) 2023-01-26
AU2022316103A1 (en) 2024-02-08
EP4373577A1 (en) 2024-05-29
ECSP24012819A (es) 2024-03-01
US20240327494A1 (en) 2024-10-03
GEAP202416461A (en) 2024-04-25
JOP20240010A1 (ar) 2024-01-18
MX2024000829A (es) 2024-04-12
CO2024001551A2 (es) 2024-03-07
CN117957014A (zh) 2024-04-30
DOP2024000016A (es) 2024-06-16

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