JP2024524301A - 活性化肝星細胞（ｈｓｃ）の枯渇及びその使用 - Google Patents

活性化肝星細胞（ｈｓｃ）の枯渇及びその使用 Download PDF

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JP2024524301A
JP2024524301A JP2023579541A JP2023579541A JP2024524301A JP 2024524301 A JP2024524301 A JP 2024524301A JP 2023579541 A JP2023579541 A JP 2023579541A JP 2023579541 A JP2023579541 A JP 2023579541A JP 2024524301 A JP2024524301 A JP 2024524301A
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amino acid
acid sequence
binding molecule
binding
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JPWO2023274352A5 (enExample
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シャンヤン ルー、クリス
ジャスティン クー、シャン―ジュ
ミンファ チャン
チャン、ルイペン
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ラエクナ セラピューティクス シャンハイ カンパニー リミテッド
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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JP2023579541A 2021-07-02 2022-06-30 活性化肝星細胞（ｈｓｃ）の枯渇及びその使用 Pending JP2024524301A (ja)

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CNPCT/CN2021/104201 2021-07-02
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PCT/CN2022/102692 WO2023274352A1 (en) 2021-07-02 2022-06-30 Depletion of activated hepatic stellate cells (hscs) and uses thereof

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KR (1) KR20240070496A (enExample)
CN (2) CN119039440A (enExample)
AU (1) AU2022304943A1 (enExample)
CA (1) CA3222788A1 (enExample)
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CN115443150A (zh) 2019-12-17 2022-12-06 德克萨斯大学系统董事会 新型ddr1抗体和其用途
CN116492463B (zh) * 2023-03-31 2023-11-17 珠海市人民医院 Cd155分子在肝纤维化领域中的应用
TW202513591A (zh) * 2023-08-01 2025-04-01 大陸商來凱醫藥科技（上海）有限公司 抗acvr2b抗體及其用途
CN119930817B (zh) * 2024-12-24 2025-12-02 国科大杭州高等研究院 Tigit全人源抗体及其制备方法与应用

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US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US7317091B2 (en) * 2002-03-01 2008-01-08 Xencor, Inc. Optimized Fc variants
AU2011265460B2 (en) * 2003-01-09 2014-07-17 Macrogenics, Inc. Identification and engineering of antibodies with variant Fc regions and methods of using same
AU2012261721A1 (en) * 2006-03-17 2013-01-10 Gilead Sciences, Inc. Method of preventing and treating hepatic disease using A2B adenosine receptor antagonists
CA2827170A1 (en) * 2011-02-11 2012-08-16 David M. Hilbert Monovalent and multivalent multispecific complexes and uses thereof
CN104628866B (zh) * 2015-01-21 2018-03-27 中国药科大学 一种靶向vegfr2的抗体融合蛋白的制备及其用途
CN104592395B (zh) * 2015-01-27 2017-11-14 中国药科大学 Vegfr2单链抗体与mica融合蛋白的制备方法及用途
CA3007898A1 (en) * 2015-12-28 2017-07-06 Innate Pharma Variable regions for nkp46 binding proteins
SG11201901077RA (en) * 2016-08-17 2019-03-28 Compugen Ltd Anti-tigit antibodies, anti-pvrig antibodies and combinations thereof
AU2019225249A1 (en) * 2018-02-26 2020-09-17 Genentech, Inc. Dosing for treatment with anti-tigit and anti-PD-L1 antagonist antibodies
GB201809700D0 (en) * 2018-06-13 2018-08-01 Singapore Health Serv Pte Ltd IL-11 antibodies
JP2022532430A (ja) * 2019-05-16 2022-07-14 シャタック ラボ，インコーポレイテッド Ｎｋ細胞指向性キメラタンパク質

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CA3222788A1 (en) 2023-01-05
EP4363443A1 (en) 2024-05-08
CN117980328A (zh) 2024-05-03
MX2024000057A (es) 2024-04-02
IL309804A (en) 2024-02-01
AU2022304943A1 (en) 2024-01-18
KR20240070496A (ko) 2024-05-21
TW202317632A (zh) 2023-05-01
US20240254239A1 (en) 2024-08-01
CN119039440A (zh) 2024-11-29
WO2023274352A1 (en) 2023-01-05

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